D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 77 Citations 18,271 346 World Ranking 13544 National Ranking 7022

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Internal medicine

His primary areas of investigation include Internal medicine, Endocrinology, Diabetic cardiomyopathy, Diabetes mellitus and Oxidative stress. His research integrates issues of Apoptosis, Downregulation and upregulation, Kinase and Type 2 diabetes in his study of Internal medicine. Lu Cai specializes in Endocrinology, namely Streptozotocin.

His Diabetic cardiomyopathy research includes themes of NADPH oxidase, Angiotensin II and Plasminogen activator inhibitor-1. His Diabetes mellitus study combines topics in areas such as Glycogen synthase, Insulin, Zinc deficiency and Pathogenesis. His Oxidative stress research incorporates themes from Cardiology, Reactive oxygen species, Bioinformatics and Hyperlipidemia.

His most cited work include:

  • Hyperglycemia-Induced Apoptosis in Mouse Myocardium: Mitochondrial Cytochrome c–Mediated Caspase-3 Activation Pathway (508 citations)
  • Biological stress response terminology: Integrating the concepts of adaptive response and preconditioning stress within a hormetic dose-response framework (477 citations)
  • Oxidative stress and diabetic cardiomyopathy: a brief review. (296 citations)

What are the main themes of his work throughout his whole career to date?

Internal medicine, Endocrinology, Diabetes mellitus, Oxidative stress and Diabetic cardiomyopathy are his primary areas of study. Lu Cai has researched Internal medicine in several fields, including Downregulation and upregulation and Programmed cell death. His Endocrinology research is multidisciplinary, relying on both Protein kinase B and Metallothionein.

His Diabetes mellitus research integrates issues from Zinc deficiency, Insulin and Pathology. His research investigates the connection between Oxidative stress and topics such as Lipid metabolism that intersect with issues in AMPK. His Diabetic cardiomyopathy study combines topics from a wide range of disciplines, such as Cardiac function curve and Bioinformatics.

He most often published in these fields:

  • Internal medicine (94.84%)
  • Endocrinology (89.40%)
  • Diabetes mellitus (50.14%)

What were the highlights of his more recent work (between 2018-2021)?

  • Internal medicine (94.84%)
  • Endocrinology (89.40%)
  • Diabetes mellitus (50.14%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are Internal medicine, Endocrinology, Diabetes mellitus, Oxidative stress and Inflammation. His research ties Fatty acid and Internal medicine together. His research integrates issues of AMPK and Protein kinase B in his study of Endocrinology.

The study incorporates disciplines such as Acquired immune system, Angiogenesis, Diabetic cardiomyopathy and Bone remodeling in addition to Diabetes mellitus. The various areas that Lu Cai examines in his Oxidative stress study include Fibrosis and Steatosis. Lu Cai interconnects Autophagy, Cardiomyopathy, Intermittent hypoxia, Glycation and Pharmacology in the investigation of issues within Inflammation.

Between 2018 and 2021, his most popular works were:

  • Mechanisms of diabetic cardiomyopathy and potential therapeutic strategies: preclinical and clinical evidence (48 citations)
  • Curcuminoids: Implication for inflammation and oxidative stress in cardiovascular diseases. (27 citations)
  • Role of sirtuin-1 in diabetic nephropathy (27 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Internal medicine

Lu Cai mainly focuses on Internal medicine, Endocrinology, Inflammation, Oxidative stress and Pathogenesis. His work carried out in the field of Internal medicine brings together such families of science as Palmitic acid and Streptozotocin. His research is interdisciplinary, bridging the disciplines of Fatty acid and Endocrinology.

As a part of the same scientific study, he usually deals with the Inflammation, concentrating on Pharmacology and frequently concerns with Fibrosis. His Oxidative stress study frequently draws connections between adjacent fields such as Diabetes mellitus. His studies deal with areas such as Clinical trial, Bioinformatics, Diabetic cardiomyopathy and Heart failure as well as Diabetes mellitus.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Hyperglycemia-Induced Apoptosis in Mouse Myocardium: Mitochondrial Cytochrome c–Mediated Caspase-3 Activation Pathway

Lu Cai;Wei Li;Guangwu Wang;Luping Guo.
Diabetes (2002)

848 Citations

Biological stress response terminology: Integrating the concepts of adaptive response and preconditioning stress within a hormetic dose-response framework

Edward J. Calabrese;Kenneth A. Bachmann;A. John Bailer;P. Michael Bolger.
Toxicology and Applied Pharmacology (2007)

680 Citations

Oxidative stress and diabetic cardiomyopathy: a brief review.

L Cai;Y J Kang;Y J Kang.
Cardiovascular Toxicology (2001)

492 Citations

Attenuation by Metallothionein of Early Cardiac Cell Death via Suppression of Mitochondrial Oxidative Stress Results in a Prevention of Diabetic Cardiomyopathy

Lu Cai;Lu Cai;Yuehui Wang;Guihua Zhou;Teresa Chen.
Journal of the American College of Cardiology (2006)

424 Citations

Diabetic Downregulation of Nrf2 Activity via ERK Contributes to Oxidative Stress–Induced Insulin Resistance in Cardiac Cells In Vitro and In Vivo

Yi Tan;Tomonaga Ichikawa;Jinqing Li;Qiusheng Si.
Diabetes (2011)

351 Citations

miRNAS in cardiovascular diseases: potential biomarkers, therapeutic targets and challenges

Shan-shan Zhou;Jing-peng Jin;Ji-qun Wang;Ji-qun Wang;Zhi-guo Zhang;Zhi-guo Zhang.
Acta Pharmacologica Sinica (2018)

345 Citations

Nrf2 is critical in defense against high glucose-induced oxidative damage in cardiomyocytes

Xiaoqing He;Hong Kan;Lu Cai;Qiang Ma.
Journal of Molecular and Cellular Cardiology (2009)

301 Citations

Prevention by sulforaphane of diabetic cardiomyopathy is associated with up-regulation of Nrf2 expression and transcription activation

Yang Bai;Wenpeng Cui;Wenpeng Cui;Ying Xin;Ying Xin;Xiao Miao;Xiao Miao.
Journal of Molecular and Cellular Cardiology (2013)

248 Citations

Cardiac Metallothionein Induction Plays the Major Role in the Prevention of Diabetic Cardiomyopathy by Zinc Supplementation

Jianxun Wang;Ye Song;Laila Elsherif;Zhenyuan Song.
Circulation (2006)

247 Citations

Advanced Glycation End-Products Induce Connective Tissue Growth Factor-Mediated Renal Fibrosis Predominantly through Transforming Growth Factor β-Independent Pathway

Guihua Zhou;Cai Li;Lu Cai;Lu Cai.
American Journal of Pathology (2004)

236 Citations

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