His primary areas of investigation include Internal medicine, Endocrinology, Diabetic cardiomyopathy, Diabetes mellitus and Oxidative stress. His research integrates issues of Apoptosis, Downregulation and upregulation, Kinase and Type 2 diabetes in his study of Internal medicine. Lu Cai specializes in Endocrinology, namely Streptozotocin.
His Diabetic cardiomyopathy research includes themes of NADPH oxidase, Angiotensin II and Plasminogen activator inhibitor-1. His Diabetes mellitus study combines topics in areas such as Glycogen synthase, Insulin, Zinc deficiency and Pathogenesis. His Oxidative stress research incorporates themes from Cardiology, Reactive oxygen species, Bioinformatics and Hyperlipidemia.
Internal medicine, Endocrinology, Diabetes mellitus, Oxidative stress and Diabetic cardiomyopathy are his primary areas of study. Lu Cai has researched Internal medicine in several fields, including Downregulation and upregulation and Programmed cell death. His Endocrinology research is multidisciplinary, relying on both Protein kinase B and Metallothionein.
His Diabetes mellitus research integrates issues from Zinc deficiency, Insulin and Pathology. His research investigates the connection between Oxidative stress and topics such as Lipid metabolism that intersect with issues in AMPK. His Diabetic cardiomyopathy study combines topics from a wide range of disciplines, such as Cardiac function curve and Bioinformatics.
His primary areas of study are Internal medicine, Endocrinology, Diabetes mellitus, Oxidative stress and Inflammation. His research ties Fatty acid and Internal medicine together. His research integrates issues of AMPK and Protein kinase B in his study of Endocrinology.
The study incorporates disciplines such as Acquired immune system, Angiogenesis, Diabetic cardiomyopathy and Bone remodeling in addition to Diabetes mellitus. The various areas that Lu Cai examines in his Oxidative stress study include Fibrosis and Steatosis. Lu Cai interconnects Autophagy, Cardiomyopathy, Intermittent hypoxia, Glycation and Pharmacology in the investigation of issues within Inflammation.
Lu Cai mainly focuses on Internal medicine, Endocrinology, Inflammation, Oxidative stress and Pathogenesis. His work carried out in the field of Internal medicine brings together such families of science as Palmitic acid and Streptozotocin. His research is interdisciplinary, bridging the disciplines of Fatty acid and Endocrinology.
As a part of the same scientific study, he usually deals with the Inflammation, concentrating on Pharmacology and frequently concerns with Fibrosis. His Oxidative stress study frequently draws connections between adjacent fields such as Diabetes mellitus. His studies deal with areas such as Clinical trial, Bioinformatics, Diabetic cardiomyopathy and Heart failure as well as Diabetes mellitus.
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Hyperglycemia-Induced Apoptosis in Mouse Myocardium: Mitochondrial Cytochrome c–Mediated Caspase-3 Activation Pathway
Lu Cai;Wei Li;Guangwu Wang;Luping Guo.
Biological stress response terminology: Integrating the concepts of adaptive response and preconditioning stress within a hormetic dose-response framework
Edward J. Calabrese;Kenneth A. Bachmann;A. John Bailer;P. Michael Bolger.
Toxicology and Applied Pharmacology (2007)
Oxidative stress and diabetic cardiomyopathy: a brief review.
L Cai;Y J Kang;Y J Kang.
Cardiovascular Toxicology (2001)
Attenuation by Metallothionein of Early Cardiac Cell Death via Suppression of Mitochondrial Oxidative Stress Results in a Prevention of Diabetic Cardiomyopathy
Lu Cai;Lu Cai;Yuehui Wang;Guihua Zhou;Teresa Chen.
Journal of the American College of Cardiology (2006)
Diabetic Downregulation of Nrf2 Activity via ERK Contributes to Oxidative Stress–Induced Insulin Resistance in Cardiac Cells In Vitro and In Vivo
Yi Tan;Tomonaga Ichikawa;Jinqing Li;Qiusheng Si.
miRNAS in cardiovascular diseases: potential biomarkers, therapeutic targets and challenges
Shan-shan Zhou;Jing-peng Jin;Ji-qun Wang;Ji-qun Wang;Zhi-guo Zhang;Zhi-guo Zhang.
Acta Pharmacologica Sinica (2018)
Nrf2 is critical in defense against high glucose-induced oxidative damage in cardiomyocytes
Xiaoqing He;Hong Kan;Lu Cai;Qiang Ma.
Journal of Molecular and Cellular Cardiology (2009)
Prevention by sulforaphane of diabetic cardiomyopathy is associated with up-regulation of Nrf2 expression and transcription activation
Yang Bai;Wenpeng Cui;Wenpeng Cui;Ying Xin;Ying Xin;Xiao Miao;Xiao Miao.
Journal of Molecular and Cellular Cardiology (2013)
Cardiac Metallothionein Induction Plays the Major Role in the Prevention of Diabetic Cardiomyopathy by Zinc Supplementation
Jianxun Wang;Ye Song;Laila Elsherif;Zhenyuan Song.
Advanced Glycation End-Products Induce Connective Tissue Growth Factor-Mediated Renal Fibrosis Predominantly through Transforming Growth Factor β-Independent Pathway
Guihua Zhou;Cai Li;Lu Cai;Lu Cai.
American Journal of Pathology (2004)
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