His main research concerns Biochemistry, Proteomics, Oxidative stress, Alzheimer's disease and Kinase. Biochemistry connects with themes related to Neurodegeneration in his study. His studies deal with areas such as Proteome, Biomarker identification and Ultracentrifuge as well as Proteomics.
His Alzheimer's disease research is multidisciplinary, relying on both Amyloid and Protein oxidation. His work deals with themes such as Apoptosis, Protein kinase B, Phosphorylation and Cancer research, which intersect with Kinase. His Protein kinase B study combines topics in areas such as Molecular biology and Phosphatidylinositol.
His primary scientific interests are in Proteomics, Internal medicine, Biochemistry, Endocrinology and Molecular biology. His Proteomics research includes themes of Proteome, Bioinformatics and Computational biology. His studies in Proteome integrate themes in fields like Biomarker, Polyacrylamide gel electrophoresis and Urinary system.
His work in the fields of Internal medicine, such as Kidney, Renal function and Hemodialysis, intersects with other areas such as In patient. His research in Biochemistry intersects with topics in Neurodegeneration and Cell biology. In his study, Cancer research and Apoptosis is strongly linked to Kinase, which falls under the umbrella field of Molecular biology.
His scientific interests lie mostly in Pathology, Proteomics, Internal medicine, Immunology and Proteome. His Pathology research incorporates themes from Focal segmental glomerulosclerosis, Membranoproliferative glomerulonephritis and Glomerulonephritis. His Proteomics research includes elements of Malignancy, Bioinformatics, Immune system, Cell biology and Neuroscience.
He frequently studies issues relating to Molecular biology and Cell biology. His research on Internal medicine often connects related topics like Endocrinology. His study looks at the relationship between Proteome and fields such as Kidney, as well as how they intersect with chemical problems.
Jon B. Klein mainly focuses on Internal medicine, Albuminuria, Renal function, Oxidative stress and Endocrinology. His work on Cohort, Disease and Clinical trial as part of general Internal medicine research is often related to Diagnosis code and Genome-wide association study, thus linking different fields of science. Jon B. Klein interconnects Type 1 diabetes, Diabetic nephropathy, Microalbuminuria and Case-control study in the investigation of issues within Albuminuria.
His studies deal with areas such as Urine, Urinary system, Kidney disease and Urology as well as Renal function. His Oxidative stress research entails a greater understanding of Biochemistry. As part of his studies on Endocrinology, he often connects relevant subjects like Kinase.
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M-type phospholipase A2 receptor as target antigen in idiopathic membranous nephropathy.
Laurence H. Beck;Ramon G.B. Bonegio;Gérard Lambeau;David M. Beck.
The New England Journal of Medicine (2009)
Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part II: dihydropyrimidinase-related protein 2, α-enolase and heat shock cognate 71
Alessandra Castegna;Michael Aksenov;Visith Thongboonkerd;Jon B. Klein.
Journal of Neurochemistry (2002)
Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part I: creatine kinase BB, glutamine synthase, and ubiquitin carboxy-terminal hydrolase L-1.
Alessandra Castegna;Michael Aksenov;Marina Aksenova;Visith Thongboonkerd.
Free Radical Biology and Medicine (2002)
Proteomic identification of nitrated proteins in Alzheimer's disease brain.
Alessandra Castegna;Visith Thongboonkerd;Jon B. Klein;Bert Lynn.
Journal of Neurochemistry (2003)
Thrombospondin Type-1 Domain-Containing 7A in Idiopathic Membranous Nephropathy
Nicola M Tomas;Laurence H Beck;Catherine Meyer-Schwesinger;Barbara Seitz-Polski.
The New England Journal of Medicine (2014)
Heat shock protein 27 controls apoptosis by regulating Akt activation.
Madhavi J. Rane;Yong Pan;Saurabh Singh;David W. Powell.
Journal of Biological Chemistry (2003)
Proteomic analysis of normal human urinary proteins isolated by acetone precipitation or ultracentrifugation
Visith Thongboonkerd;Kenneth R. Mcleish;Kenneth R. Mcleish;Kenneth R. Mcleish;John M. Arthur;John M. Arthur;John M. Arthur;Jon B. Klein;Jon B. Klein;Jon B. Klein.
Kidney International (2002)
Identification of nitrated proteins in Alzheimer's disease brain using a redox proteomics approach.
Rukhsana Sultana;H. Fai Poon;Jian Cai;William M. Pierce.
Neurobiology of Disease (2006)
Redox proteomics identification of oxidatively modified hippocampal proteins in mild cognitive impairment: Insights into the development of Alzheimer's disease
D. Allan Butterfield;H. Fai Poon;Daret St. Clair;Jeffery N. Keller.
Neurobiology of Disease (2006)
Granulocyte-Macrophage Colony-Stimulating Factor Delays Neutrophil Constitutive Apoptosis Through Phosphoinositide 3-Kinase and Extracellular Signal-Regulated Kinase Pathways
Jon B. Klein;Madhavi J. Rane;Janice A. Scherzer;Patricia Y. Coxon.
Journal of Immunology (2000)
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