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Roger Schibli

Roger Schibli

D-Index & Metrics

Chemistry

D-Index
74
Citations
19597
World Ranking
4690
National Ranking
107

Overview

Roger Schibli is a researcher affiliated with ETH Zurich in Switzerland. Their academic contributions span primarily within the field of Medicine, with a notable focus on subfields such as Radiology, Nuclear Medicine and Imaging, Oncology, Pulmonary and Respiratory Medicine, Molecular Biology, and Epidemiology.

Their research work extensively covers several major topics, including Radiopharmaceutical Chemistry and Applications, Medical Imaging Techniques and Applications, Peptidase Inhibition and Analysis, Neuroendocrine Tumor Research Advances, Prostate Cancer Treatment and Research, Lung Cancer Research Studies, and Neuroscience and Neuropharmacology Research.

Schibli's recent papers include:

  • Tauvid™: The First FDA-Approved PET Tracer for Imaging Tau Pathology in Alzheimer's Disease (2021, Pharmaceuticals)
  • Development of a new class of PSMA radioligands comprising ibuprofen as an albumin-binding entity (2020, Theranostics)
  • Combination of terbium-161 with somatostatin receptor antagonists-a potential paradigm shift for the treatment of neuroendocrine neoplasms (2021, European Journal of Nuclear Medicine and Molecular Imaging)
  • First-in-Humans Application of 161Tb: A Feasibility Study Using 161Tb-DOTATOC (2021, Journal of Nuclear Medicine)
  • On the consensus nomenclature rules for radiopharmaceutical chemistry - Reconsideration of radiochemical conversion (2020, Nuclear Medicine and Biology)

Frequent co-authors in Schibli's publications include Cristina Müller, Linjing Mu, Nicholas P. van der Meulen, Martin Béhé, and Pascal V. Grundler. These collaborative efforts indicate a consistent teamwork presence in their research output.

Schibli has contributed to various publication venues, with the largest number of works appearing in Nuclear Medicine and Biology, European Journal of Nuclear Medicine and Molecular Imaging, and Journal of Nuclear Medicine. Other publication venues include Cancers and EJNMMI Research.

  • Nuclear Medicine and Biology
  • European Journal of Nuclear Medicine and Molecular Imaging
  • Journal of Nuclear Medicine
  • Cancers
  • EJNMMI Research

The diversity of Schibli's research topics and publication outlets illustrates a multidisciplinary approach primarily anchored in nuclear medicine and oncological imaging techniques, with applications ranging from neurodegenerative disease imaging to cancer treatment research. This profile reflects an ongoing engagement with both fundamental radiopharmaceutical chemistry and applied clinical imaging.

Best Publications

  • A Novel Organometallic Aqua Complex of Technetium for the Labeling of Biomolecules: Synthesis of [99mTc(OH2)3(CO)3]+ from [99mTcO4]- in Aqueous Solution and Its Reaction with a Bifunctional Ligand

    Roger Alberto;Roger Schibli;and André Egli;August P. Schubiger

  • Synthesis and properties of boranocarbonate: a convenient in situ CO source for the aqueous preparation of [(99m)Tc(OH(2))3(CO)3]+.

    Roger Alberto;Kirstin Ortner;Nigel Wheatley;Roger Schibli

  • Metal chelating systems synthesized using the copper(I) catalyzed azide-alkyne cycloaddition.

    Harriet Struthers;Thomas L. Mindt;Roger Schibli

  • Influence of the denticity of ligand systems on the in vitro and in vivo behavior of (99m)Tc(I)-tricarbonyl complexes: a hint for the future functionalization of biomolecules.

    R Schibli;R La Bella;R Alberto;E Garcia-Garayoa

  • Basic aqueous chemistry of [M(OH2)3(CO)3]+ (M=Re, Tc) directed towards radiopharmaceutical application

    Roger Alberto;Roger Schibli;Robert Waibel;Ulrich Abram

  • "Click to chelate": synthesis and installation of metal chelates into biomolecules in a single step.

    Thomas L. Mindt;Harriet Struthers;Luc Brans;Todor Anguelov

  • Current use and future potential of organometallic radiopharmaceuticals

    Roger Schibli;August P. Schubiger

  • Stable one-step technetium-99m labeling of His-tagged recombinant proteins with a novel Tc(I)-carbonyl complex.

    R Waibel;R Alberto;J Willuda;R Finnern

  • Site-specific and stoichiometric modification of antibodies by bacterial transglutaminase.

    Simone Jeger;Kurt Zimmermann;Alain Blanc;Jürgen Grünberg

  • Efficient tumor targeting with high-affinity designed ankyrin repeat proteins: effects of affinity and molecular size.

    Christian Zahnd;Martin Kawe;Michael T. Stumpp;Christine de Pasquale

  • Transglutaminase-Based Chemo-Enzymatic Conjugation Approach Yields Homogeneous Antibody–Drug Conjugates

    Patrick Dennler;Aristeidis Chiotellis;Eliane Fischer;Delphine Brégeon

  • In vivo anti-tumor activity of the organometallic ruthenium(II)-arene complex [Ru(eta(6)-p-cymene)-Cl-2(pta)] (RAPTA-C) in human ovarian and colorectal carcinomas

    Andrea Weiss;Andrea Weiss;Robert H. Berndsen;Maxime Dubois;Cristina Müller

  • A Unique Matched Quadruplet of Terbium Radioisotopes for PET and SPECT and for α- and β−-Radionuclide Therapy: An In Vivo Proof-of-Concept Study with a New Receptor-Targeted Folate Derivative

    Christina Müller;Konstantin Zhernosekov;Ulli Köster;Karl Johnston

  • Steps toward high specific activity labeling of biomolecules for therapeutic application: preparation of precursor [(188)Re(H(2)O)(3)(CO)(3)](+) and synthesis of tailor-made bifunctional ligand systems.

    Roger Schibli;Rolf Schwarzbach;Roger Alberto;Kirstin Ortner

  • “Click-to-Chelate”: Design and Incorporation of Triazole-Containing Metal-Chelating Systems into Biomolecules of Diagnostic and Therapeutic Interest

    Harriet Struthers;Harriet Struthers;Bernhard Spingler;Thomas L. Mindt;Roger Schibli;Roger Schibli

  • Transplantation and Tracking of Human-Induced Pluripotent Stem Cells in a Pig Model of Myocardial Infarction Assessment of Cell Survival, Engraftment, and Distribution by Hybrid Single Photon Emission Computed Tomography/Computed Tomography of Sodium Iodide Symporter Transgene Expression

    Christian Templin;Robert Zweigerdt;Kristin Schwanke;Ruth Olmer

  • Promising Prospects for 44Sc-/47Sc-Based Theragnostics: Application of 47Sc for Radionuclide Tumor Therapy in Mice

    Cristina Müller;Maruta Bunka;Maruta Bunka;Stephanie Haller;Ulli Köster

  • Organometallic 99mTc-aquaion labels peptide to an unprecedented high specific activity.

    A Egli;R Alberto;L Tannahill;R Schibli

  • Terbium-161 for PSMA-targeted radionuclide therapy of prostate cancer

    Cristina Müller;Christoph A. Umbricht;Nadezda Gracheva;Viviane J. Tschan

  • The low-energy β− and electron emitter 161Tb as an alternative to 177Lu for targeted radionuclide therapy

    Silvia Lehenberger;Christoph Barkhausen;Susan Cohrs;Eliane Fischer

  • Folic Acid Conjugates for Nuclear Imaging of Folate Receptor–Positive Cancer

    Cristina Müller;Roger Schibli

  • Reactions with the technetium and rhenium carbonyl complexes (NEt4)2[MX3(CO)3]. Synthesis and structure of [Tc(CN-But)3(CO)3](NO3) and (NEt4)[Tc2(μ-SCH2CH2OH)3(CO)6]

    Roger Alberto;Roger Schibli;P. August Schubiger;Ulrich Abram

Frequent Co-Authors

Andreas Türler
Andreas Türler University of Bern
Roger Alberto
Roger Alberto University of Zurich
Dirk Tourwé
Dirk Tourwé Vrije Universiteit Brussel
Philipp A. Kaufmann
Philipp A. Kaufmann University of Zurich
Wynn A. Volkert
Wynn A. Volkert University of Missouri
Bernhard Spingler
Bernhard Spingler University of Zurich
Rolf Gruetter
Rolf Gruetter École Polytechnique Fédérale de Lausanne
Oliver Distler
Oliver Distler University of Zurich
Marion de Jong
Marion de Jong Erasmus University Rotterdam
Alfred Buck
Alfred Buck University of Zurich

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