D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Chemistry D-index 67 Citations 15,788 296 World Ranking 3125 National Ranking 86

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Organic chemistry
  • Internal medicine

His main research concerns Folate receptor, Conjugate, Biochemistry, Chelation and Click chemistry. His Folate receptor study incorporates themes from Specific activity, Biodistribution, Radionuclide therapy, Positron emission tomography and Spect imaging. Roger Schibli has included themes like Radiochemistry and DOTA in his Radionuclide therapy study.

His Chelation research includes themes of Substitution reaction, Ligand, Metal, Stereochemistry and Amine gas treating. Click chemistry is a subfield of Combinatorial chemistry that Roger Schibli explores. As a part of the same scientific family, Roger Schibli mostly works in the field of In vitro, focusing on Distribution and, on occasion, Cancer research, Cancer and Folic acid.

His most cited work include:

  • A Novel Organometallic Aqua Complex of Technetium for the Labeling of Biomolecules: Synthesis of [99mTc(OH2)3(CO)3]+ from [99mTcO4]- in Aqueous Solution and Its Reaction with a Bifunctional Ligand (546 citations)
  • Synthesis and properties of boranocarbonate: a convenient in situ CO source for the aqueous preparation of [(99m)Tc(OH(2))3(CO)3]+. (346 citations)
  • Metal chelating systems synthesized using the copper(I) catalyzed azide-alkyne cycloaddition. (313 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of study are In vitro, Biodistribution, Biochemistry, Folate receptor and Stereochemistry. While the research belongs to areas of In vitro, Roger Schibli spends his time largely on the problem of Pathology, intersecting his research to questions surrounding Positron emission tomography and Preclinical imaging. His Biodistribution research focuses on Pharmacology and how it connects with Albumin and Kidney.

His Folate receptor study integrates concerns from other disciplines, such as Pemetrexed, Cancer research and Radionuclide therapy. His Stereochemistry study combines topics from a wide range of disciplines, such as Medicinal chemistry, Chelation, Ligand, Rhenium and Derivative. His Chelation research is multidisciplinary, incorporating elements of Combinatorial chemistry and Click chemistry.

He most often published in these fields:

  • In vitro (36.70%)
  • Biodistribution (27.96%)
  • Biochemistry (22.52%)

What were the highlights of his more recent work (between 2017-2021)?

  • Biodistribution (27.96%)
  • In vitro (36.70%)
  • Receptor (18.06%)

In recent papers he was focusing on the following fields of study:

Biodistribution, In vitro, Receptor, Radioligand and Cancer research are his primary areas of study. The various areas that Roger Schibli examines in his Biodistribution study include Ex vivo, Molecular biology, Albumin, Pharmacology and Folate receptor. His work focuses on many connections between Folate receptor and other disciplines, such as Pet tracer, that overlap with his field of interest in Biochemistry.

Roger Schibli combines subjects such as Radiochemistry and Biophysics with his study of In vitro. His biological study spans a wide range of topics, including Insulinoma, Stereochemistry, Positron emission tomography and Peptidomimetic, Peptide. His Cancer research research focuses on Radionuclide therapy and how it relates to DOTA, Chelation, Therapeutic effect, Specific activity and Radiation therapy.

Between 2017 and 2021, his most popular works were:

  • Albumin-Binding PSMA Ligands: Optimization of the Tissue Distribution Profile. (41 citations)
  • Albumin-Binding PSMA Ligands: Optimization of the Tissue Distribution Profile. (41 citations)
  • Preclinical Development of Novel PSMA-Targeting Radioligands: Modulation of Albumin-Binding Properties to Improve Prostate Cancer Therapy (35 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Organic chemistry
  • Internal medicine

Roger Schibli mainly focuses on Biodistribution, Radioligand, Radionuclide therapy, Prostate cancer and In vitro. His research integrates issues of Ex vivo, Brachytherapy, Receptor, Antagonist and Stereochemistry in his study of Biodistribution. Roger Schibli conducts interdisciplinary study in the fields of Stereochemistry and Conjugate through his works.

His Radionuclide therapy research incorporates elements of Yield, Extraction, Chelation, DOTA and Radiochemistry. His research in In vitro is mostly focused on Viability assay. His research investigates the connection between Nuclear medicine and topics such as Urinary bladder that intersect with issues in Folate receptor.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

A Novel Organometallic Aqua Complex of Technetium for the Labeling of Biomolecules: Synthesis of [99mTc(OH2)3(CO)3]+ from [99mTcO4]- in Aqueous Solution and Its Reaction with a Bifunctional Ligand

Roger Alberto;Roger Schibli;and André Egli;August P. Schubiger.
Journal of the American Chemical Society (1998)

842 Citations

Synthesis and properties of boranocarbonate: a convenient in situ CO source for the aqueous preparation of [(99m)Tc(OH(2))3(CO)3]+.

Roger Alberto;Kirstin Ortner;Nigel Wheatley;Roger Schibli.
Journal of the American Chemical Society (2001)

526 Citations

Metal chelating systems synthesized using the copper(I) catalyzed azide-alkyne cycloaddition.

Harriet Struthers;Thomas L. Mindt;Roger Schibli.
Dalton Transactions (2010)

479 Citations

Influence of the denticity of ligand systems on the in vitro and in vivo behavior of (99m)Tc(I)-tricarbonyl complexes: a hint for the future functionalization of biomolecules.

R Schibli;R La Bella;R Alberto;E Garcia-Garayoa.
Bioconjugate Chemistry (2000)

468 Citations

Basic aqueous chemistry of [M(OH2)3(CO)3]+ (M=Re, Tc) directed towards radiopharmaceutical application

Roger Alberto;Roger Schibli;Robert Waibel;Ulrich Abram.
Coordination Chemistry Reviews (1999)

405 Citations

Current use and future potential of organometallic radiopharmaceuticals

Roger Schibli;August P. Schubiger.
European Journal of Nuclear Medicine and Molecular Imaging (2002)

384 Citations

"Click to chelate": synthesis and installation of metal chelates into biomolecules in a single step.

Thomas L. Mindt;Harriet Struthers;Luc Brans;Todor Anguelov.
Journal of the American Chemical Society (2006)

384 Citations

Stable one-step technetium-99m labeling of His-tagged recombinant proteins with a novel Tc(I)-carbonyl complex.

R Waibel;R Alberto;J Willuda;R Finnern.
Nature Biotechnology (1999)

382 Citations

Efficient tumor targeting with high-affinity designed ankyrin repeat proteins: effects of affinity and molecular size.

Christian Zahnd;Martin Kawe;Michael T. Stumpp;Christine de Pasquale.
Cancer Research (2010)

297 Citations

Site-specific and stoichiometric modification of antibodies by bacterial transglutaminase.

Simone Jeger;Kurt Zimmermann;Alain Blanc;Jürgen Grünberg.
Angewandte Chemie (2010)

274 Citations

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