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Andreas Plückthun

Andreas Plückthun

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Biology and Biochemistry
Switzerland
2026

D-Index & Metrics

Biology and Biochemistry

D-Index
135
Citations
61604
World Ranking
353
National Ranking
10

Andreas Plückthun publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Andreas Plückthun sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 592 publications — 97th percentile

97% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Andreas Plückthun D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Andreas Plückthun sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 135 D-Index — 98th percentile

98% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in Switzerland Leader Award
  • 2025 - Research.com Biology and Biochemistry in Switzerland Leader Award
  • 2023 - Research.com Biology and Biochemistry in Switzerland Leader Award
  • 2022 - Research.com Biology and Biochemistry in Switzerland Leader Award
  • 2003 - German National Academy of Sciences Leopoldina - Deutsche Akademie der Naturforscher Leopoldina – Nationale Akademie der Wissenschaften Biochemistry and Biophysics
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Andreas Plückthun is affiliated with the University of Zurich in Switzerland. Their research spans biochemistry, genetics, molecular biology, and medicine, with particular emphasis on molecular biology, oncology, radiology, nuclear medicine and imaging, genetics, and cell biology.

The main topics of their scientific work include:

  • Monoclonal and Polyclonal Antibodies Research
  • Receptor Mechanisms and Signaling
  • Virus-based gene therapy research
  • Viral Infectious Diseases and Gene Expression in Insects
  • CAR-T cell therapy research
  • RNA and protein synthesis mechanisms
  • Neuropeptides and Animal Physiology

Andreas Plückthun has contributed to numerous scientific publications. Recent papers include:

  • Cryo-EM structure of an activated GPCR-G protein complex in lipid nanodiscs, 2021, Nature Structural & Molecular Biology
  • Flavonol-mediated stabilization of PIN efflux complexes regulates polar auxin transport, 2020, The EMBO Journal
  • Animal-free alternatives and the antibody iceberg, 2020, Nature Biotechnology
  • Crystal structure of the human oxytocin receptor, 2020, Science Advances
  • Engineering Af1521 improves ADP-ribose binding and identification of ADP-ribosylated proteins, 2020, Nature Communications

The scientist frequently publishes in several venues, including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Science Advances
  • Nature Structural & Molecular Biology
  • mAbs

Significant collaborative relationships are evident through co-authorship with:

  • Birgit Dreier
  • Jonas V. Schaefer
  • Patrick C. Freitag
  • Dominik Brücher
  • Patrick Erñst

Awards received include membership in the German National Academy of Sciences Leopoldina, recognized in biochemistry and biophysics, awarded in 2003, as well as membership in the European Molecular Biology Organization (EMBO).

Best Publications

  • In vitro selection and evolution of functional proteins by using ribosome display.

    Jozef Hanes;Andreas Plückthun

  • Assembly of a functional immunoglobulin Fv fragment in Escherichia coli.

    Arne Skerra;Andreas Plückthun

  • Fully synthetic human combinatorial antibody libraries (HuCAL) based on modular consensus frameworks and CDRs randomized with trinucleotides.

    Achim Knappik;Liming Ge;Annemarie Honegger;Peter Pack

  • Induction and Exhaustion of Lymphocytic Choriomeningitis Virus–specific Cytotoxic T Lymphocytes Visualized Using Soluble Tetrameric Major Histocompatibility Complex Class I–Peptide Complexes

    Awen Gallimore;Ann Glithero;Andrew Godkin;Alain C. Tissot

  • Engineering novel binding proteins from nonimmunoglobulin domains

    H Kaspar Binz;Patrick Amstutz;Andreas Plückthun

  • High-affinity binders selected from designed ankyrin repeat protein libraries.

    H Kaspar Binz;Patrick Amstutz;Andreas Kohl;Michael T Stumpp

  • In vitro generated antibodies specific for telomeric guanine-quadruplex DNA react with Stylonychia lemnae macronuclei.

    Christiane Schaffitzel;Imre Berger;Jan Postberg;Jozef Hanes

  • Stability engineering of antibody single-chain Fv fragments.

    Arne Wörn;Andreas Plückthun

  • Designing repeat proteins: well-expressed, soluble and stable proteins from combinatorial libraries of consensus ankyrin repeat proteins.

    H.Kaspar Binz;Michael T Stumpp;Patrik Forrer;Patrick Amstutz

  • Reliable cloning of functional antibody variable domains from hybridomas and spleen cell repertoires employing a reengineered phage display system

    Anke Krebber;Susanne Bornhauser;Jörg Burmester;Annemarie Honegger

  • Reproducibility: Standardize antibodies used in research

    Andrew Bradbury;Andreas Plückthun

  • Designed Ankyrin Repeat Proteins (DARPins): Binding Proteins for Research, Diagnostics, and Therapy

    Andreas Plückthun

  • Antibodies from Escherichia coli

    A. Plückthun

  • Yet Another Numbering Scheme for Immunoglobulin Variable Domains: An Automatic Modeling and Analysis Tool

    Annemarie Honegger;Andreas Plückthun

  • Picomolar affinity antibodies from a fully synthetic naive library selected and evolved by ribosome display

    Jozef Hanes;Christiane Schaffitzel;Achim Knappik;Andreas Plückthun

  • New protein engineering approaches to multivalent and bispecific antibody fragments

    Andreas Plückthun;Peter Pack

  • Stability improvement of antibodies for extracellular and intracellular applications: CDR grafting to stable frameworks and structure-based framework engineering.

    Stefan Ewert;Annemarie Honegger;Andreas Plückthun

  • In-vitro protein evolution by ribosome display and mRNA display

    Dasa Lipovsek;Andreas Plückthun

  • Miniantibodies: use of amphipathic helices to produce functional, flexibly linked dimeric FV fragments with high avidity in Escherichia coli.

    P Pack;A Plückthun

  • Trinucleotide phosphoramidites: ideal reagents for the synthesis of mixed oligonucleotides for random mutagenesis

    B Virnekäs;L Ge;A Plückthun;K C Schneider

Frequent Co-Authors

Annemarie Honegger
Annemarie Honegger University of Zurich
Uwe Zangemeister-Wittke
Uwe Zangemeister-Wittke University of Bern
Markus G. Grütter
Markus G. Grütter University of Zurich
Edward A. Dennis
Edward A. Dennis University of California, San Diego
Andrew Bradbury
Andrew Bradbury Los Alamos National Laboratory
Daniel Scott
Daniel Scott University of Waterloo
Hans Binz
Hans Binz University of Zurich
Arne Skerra
Arne Skerra Technical University of Munich
Amedeo Caflisch
Amedeo Caflisch University of Zurich

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