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D-Index & Metrics

Biology and Biochemistry

D-Index
55
Citations
10526
World Ranking
15095
National Ranking
277

Overview

Hans Binz is affiliated with the University of Zurich in Switzerland. Their research spans several main fields including Medicine and Biochemistry, Genetics and Molecular Biology, with a particular focus on subfields such as Molecular Biology, Infectious Diseases, Oncology, Radiology, Nuclear Medicine and Imaging, and Immunology.

The scientist's work centers heavily on topics related to SARS-CoV-2 and COVID-19 Research, RNA Interference and Gene Delivery, as well as Monoclonal and Polyclonal Antibodies Research. Additional research interests include CAR-T cell therapy, Biosimilars and Bioanalytical Methods, PARP inhibition in cancer therapy, and Advanced biosensing and bioanalysis techniques.

Hans Binz has published in several venues multiple times. Their frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • BioDrugs
  • Nature Biotechnology

Recent papers authored or co-authored by Hans Binz include:

  • "Beyond Antibodies: The DARPin® Drug Platform," 2020, BioDrugs
  • "The trispecific DARPin ensovibep inhibits diverse SARS-CoV-2 variants," 2022, Nature Biotechnology
  • "Highly potent anti-SARS-CoV-2 multivalent DARPin therapeutic candidates," 2020, bioRxiv (Cold Spring Harbor Laboratory)
  • "Ensovibep, a novel trispecific DARPin candidate that protects against SARS-CoV-2 variants," 2021, bioRxiv (Cold Spring Harbor Laboratory)

Throughout their research career, Hans Binz has collaborated frequently with several co-authors, including:

  • Keith M. Dawson
  • Sylvia Rothenberger
  • Daniel L. Hurdiss
  • Marcel Walser
  • Jennifer Mayor

Best Publications

  • Engineering novel binding proteins from nonimmunoglobulin domains

    H Kaspar Binz;Patrick Amstutz;Andreas Plückthun

  • High-affinity binders selected from designed ankyrin repeat protein libraries.

    H Kaspar Binz;Patrick Amstutz;Andreas Kohl;Michael T Stumpp

  • Designing repeat proteins: well-expressed, soluble and stable proteins from combinatorial libraries of consensus ankyrin repeat proteins.

    H.Kaspar Binz;Michael T Stumpp;Patrik Forrer;Patrick Amstutz

  • Designed to be stable: Crystal structure of a consensus ankyrin repeat protein

    Andreas Kohl;H. Kaspar Binz;Patrik Forrer;Michael T. Stumpp

  • Efficient tumor targeting with high-affinity designed ankyrin repeat proteins: effects of affinity and molecular size.

    Christian Zahnd;Martin Kawe;Michael T. Stumpp;Christine de Pasquale

  • Antigen-Binding, Idiotypic T-Lymphocyte Receptors

    Hans Binz;Hans Wigzell

  • Aggregate of repeat protein including repeat module

    Michael Tobias Stumpp;マイケル・トビアス・スタンプ;Patrick Forrer;パトリック・フォーラー

  • Two different VH gene products make up the T-cell receptors.

    C. A. Janeway;H. Wigzell;H. Binz

  • Shared idiotypic determinants on B and T lymphocytes reactive against the same antigenic determinants. V. Biochemical and serological characteristics of naturally occurring, soluble antigen-binding T-lymphocyte-derived molecules.

    Hans Binz;Hans Wigzell

  • A novel strategy to design binding molecules harnessing the modular nature of repeat proteins.

    Patrik Forrer;Michael T. Stumpp;H.Kaspar Binz;Andreas Plückthun

  • Folding and Unfolding Mechanism of Highly Stable Full-Consensus Ankyrin Repeat Proteins

    Svava K. Wetzel;Giovanni Settanni;Manca Kenig;H. Kaspar Binz

  • Induction of Protective Immunity in Rodents by Vaccination with a Prokaryotically Expressed Recombinant Fusion Protein Containing a Respiratory Syncytial Virus G Protein Fragment

    Ultan F. Power;Hélène Plotnicky-Gilquin;Thierry Huss;Alain Robert

  • Inhibition of Caspase-2 by a Designed Ankyrin Repeat Protein: Specificity, Structure, and Inhibition Mechanism.

    Andreas Schweizer;Heidi Roschitzki-Voser;Patrick Amstutz;Christophe Briand

  • Consensus design of repeat proteins.

    Patrik Forrer;H. Kaspar Binz;Michael T. Stumpp;Andreas Plückthun

  • T-cell idiotypes are linked to immunoglobulin heavy chain genes.

    Hans Binz;Hans Wigzell;Herve Bazin

  • Expression of recombinant proteins on the surface of the coagulase-negative bacterium Staphylococcus xylosus.

    M. Hansson;S. Ståhl;Thien Ngoc Nguyen;T. Bächi

  • Epitope mapping by chemical modification of free and antibody-bound protein antigen.

    Andre Burnens;Stephane Demotz;Giampietro Corradin;Hans Binz

  • BINDINGSPROTEINER TIL INHIBERING AF VEGF-A-RECEPTORINTERAKTIONEN

    Stumpp Michael Tobias;Binz Hans Kaspar;Forrer Patrik

  • Cell-surface display of heterologous epitopes on Staphylococcus xylosus as a potential delivery system for oral vaccination.

    Thien Ngoc Nguyen;Marianne Hansson;Stefan Ståhl;Thomas Bächi

  • Allosteric Inhibition of Aminoglycoside Phosphotransferase by a Designed Ankyrin Repeat Protein

    Andreas Kohl;Patrick Amstutz;Petra Parizek;H. Kaspar Binz

Frequent Co-Authors

Hans Wigzell
Hans Wigzell Karolinska Institute
Mathias Uhlén
Mathias Uhlén Royal Institute of Technology
Stefan Ståhl
Stefan Ståhl Royal Institute of Technology
Per-Åke Nygren
Per-Åke Nygren Royal Institute of Technology
Andreas Plückthun
Andreas Plückthun University of Zurich
Leif C. Andersson
Leif C. Andersson University of Helsinki
Charles A. Janeway
Charles A. Janeway Yale University
Pekka Häyry
Pekka Häyry University of Helsinki
Harvey Cantor
Harvey Cantor Harvard University
Adriano Fontana
Adriano Fontana University of Zurich

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