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Biology and Biochemistry
Sweden
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
63
Citations
13489
World Ranking
10264
National Ranking
145

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Sweden Leader Award

Overview

Per-Åke Nygren is affiliated with the Royal Institute of Technology in Sweden and has contributed extensively to the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their research primarily focuses on Molecular Biology, Radiology, Nuclear Medicine and Imaging, Immunology, Oncology, and Epidemiology.

The scientist's work covers a range of main topics, including:

  • Monoclonal and Polyclonal Antibodies Research
  • Glycosylation and Glycoproteins Research
  • Immune Cell Function and Interaction
  • Peptidase Inhibition and Analysis
  • Immunotherapy and Immune Responses
  • RNA Research and Splicing
  • RNA modifications and cancer

Nygren's recent academic output includes papers published in several notable journals, with topics spanning cancer therapy, molecular imaging, and immunological studies. Selected publications include:

  • "Progress and Future Directions with Peptide-Drug Conjugates for Targeted Cancer Therapy," 2021, Molecules
  • "Discovery, optimization and biodistribution of an Affibody molecule for imaging of CD69," 2021, Scientific Reports
  • "Caprin-1 binding to the critical stress granule protein G3BP1 is influenced by pH," 2023, Open Biology
  • "Efficient Labeling of Native Human IgG by Proximity-Based Sortase-Mediated Isopeptide Ligation," 2021, Bioconjugate Chemistry
  • "Tuning antiviral CD8 T-cell response via proline-altered peptide ligand vaccination," 2020, PLoS Pathogens

The scientist frequently publishes in journals such as Scientific Reports, Blood, Molecules, Open Biology, and Bioconjugate Chemistry, reflecting a diverse engagement with both clinical and biochemical research communities.

Collaboration is a significant aspect of Nygren's academic work. Frequent coauthors include Johan Nilvebrant, Kim Anh Giang, Adnane Achour, Fredrik Lehmann, and Yumei Diao, with whom they have contributed multiple research articles.

Best Publications

  • Binding proteins selected from combinatorial libraries of an alpha-helical bacterial receptor domain.

    Karin Nord;Elin Gunneriusson;Jenny Ringdahl;Stefan Ståhl

  • Affinity Fusion Strategies for Detection, Purification, and Immobilization of Recombinant Proteins☆

    Joakim Nilsson;Stefan Ståhl;Joakim Lundeberg;Mathias Uhlén

  • Alternative binding proteins: Affibody binding proteins developed from a small three‐helix bundle scaffold

    Per-Åke Nygren

  • Specific binding of proinsulin C-peptide to human cell membranes

    R. Rigler;A. Pramanik;P. Jonasson;G. Kratz

  • Consequences of Membrane Protein Overexpression in Escherichia coli

    Samuel Wagner;Louise Baars;A. Jimmy Ytterberg;Anja Klussmeier

  • A combinatorial library of an alpha-helical bacterial receptor domain.

    Karin Nord;Joakim Nilsson;Björn Nilsson;Mathias Uhlén

  • Display of proteins on bacteria.

    Patrik Samuelson;Elin Gunneriusson;Per Ake Nygren;Stefan Ståhl

  • Affibody Molecules in Biotechnological and Medical Applications.

    Stefan Ståhl;Torbjörn Gräslund;Amelie Eriksson Karlström;Fredrik Y. Frejd

  • Scaffolds for engineering novel binding sites in proteins

    Per-Åke Nygren;Mathias Uhlén

  • Binding proteins from alternative scaffolds.

    Per-Åke Nygren;Arne Skerra

  • Engineering of a femtomolar affinity binding protein to human serum albumin

    Andreas Jonsson;Jakob Dogan;Nina Herne;Lars Abrahmsén

  • All individual domains of staphylococcal protein A show Fab binding

    Birger Jansson;Mathias Uhlén;Per-Åke Nygren

  • ProteomeBinders: planning a European resource of affinity reagents for analysis of the human proteome

    Michael J. Taussig;Oda Stoevesandt;Carl A. K. Carl A K Borrebaeck;Andrew R. Bradbury

  • Real-time monitoring of DNA manipulations using biosensor technology.

    Peter Nilsson;Björn Persson;Mathias Uhlen;Per-Åke Nygren

  • Engineering proteins to facilitate bioprocessing

    Per-Åke Nygren;Ståhl Stefan;Mathias Uhlén

  • Användning av stabiliserade protein- eller peptidkonjugat för framställning av ett läkemedel

    Nygren Per-Aake;Wigzell Hans;Uhlen Mathias

  • Analysis and use of the serum albumin binding domains of streptococcal protein G.

    Per-Åke Nygren;Margareta Eliasson;Lars Abrahmsén;Mathias Uhlén

  • Design and production of recombinant subunit vaccines

    Marianne Hansson;Per-Åke Nygren;Stefan Ståhl

  • Affinity maturation of a Taq DNA polymerase specific affibody by helix shuffling

    E. Gunneriusson;K. Nord;M. Uhlén;P.-Å. Nygren

  • Consequences of membrane protein overexpression in Escherichia coli

    Samuel Wagner;Louise Baars;A. Jimmy Ytterberg;Anja Klußmeier

Frequent Co-Authors

Mathias Uhlén
Mathias Uhlén Royal Institute of Technology
Stefan Ståhl
Stefan Ståhl Royal Institute of Technology
Hans Binz
Hans Binz University of Zurich
Peter Nilsson
Peter Nilsson Royal Institute of Technology
Sophia Hober
Sophia Hober Royal Institute of Technology
Birgitta Henriques-Normark
Birgitta Henriques-Normark Karolinska Institute
Jan Johansson
Jan Johansson Karolinska Institute
Joakim Lundeberg
Joakim Lundeberg Royal Institute of Technology
Pierre Boulanger
Pierre Boulanger Claude Bernard University Lyon 1
Silvère M. van der Maarel
Silvère M. van der Maarel Leiden University Medical Center

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