World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
113
Citations
40453
World Ranking
869
National Ranking
542

Research.com Recognitions

  • 1999 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Edward J. Goetzl is affiliated with the University of California, San Francisco in the United States. Their research spans multiple fields primarily within Medicine and Biochemistry, Genetics and Molecular Biology, contributing notably to Molecular Biology and Neurology subfields. The scientist's work also touches on Physiology, Infectious Diseases, and Rheumatology.

The core topics of their research include:

  • Extracellular vesicles in disease
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Alzheimer's disease research and treatments
  • Long-Term Effects of COVID-19
  • GDF15 and Related Biomarkers
  • COVID-19 Clinical Research Studies
  • Circular RNAs in diseases

Edward J. Goetzl has published extensively in various scientific journals, with frequent appearances in:

  • The American Journal of Medicine
  • The FASEB Journal
  • Alzheimer's Research & Therapy
  • Cells
  • Translational Psychiatry

Their notable recent papers include:

  • "SARS-CoV-2 and Mitochondrial Proteins in Neural-Derived Exosomes of COVID-19", 2022, Annals of Neurology
  • "Astrocyte- and Neuron-Derived Extracellular Vesicles from Alzheimer's Disease Patients Effect Complement-Mediated Neurotoxicity", 2020, Cells
  • "Abnormal levels of mitochondrial proteins in plasma neuronal extracellular vesicles in major depressive disorder", 2021, Molecular Psychiatry
  • "Neuronal and Astrocytic Extracellular Vesicle Biomarkers in Blood Reflect Brain Pathology in Mouse Models of Alzheimer's Disease", 2021, Cells
  • "Traumatic brain injury increases plasma astrocyte-derived exosome levels of neurotoxic complement proteins", 2020, The FASEB Journal

Frequent collaborators of Edward J. Goetzl include:

  • Dimitrios Kapogiannis
  • Carlos Nogueras-Ortiz
  • Francheska Delgado-Peraza
  • Pamela J. Yao
  • Maja Mustapić

Edward J. Goetzl was awarded the distinction of Fellow of the American Association for the Advancement of Science (AAAS) in 1999.

Best Publications

  • Identification of preclinical Alzheimer's disease by a profile of pathogenic proteins in neurally derived blood exosomes: A case-control study

    Massimo S. Fiandaca;Dimitrios Kapogiannis;Mark Mapstone;Adam Boxer

  • Characterization of a Novel Subtype of Human G Protein-coupled Receptor for Lysophosphatidic Acid

    Songzhu An;Thieu Bleu;Olivia G. Hallmark;Edward J. Goetzl

  • Sphingosine 1-phosphate and its receptors: an autocrine and paracrine network

    Hugh Rosen;Edward J. Goetzl

  • Diversity of cellular receptors and functions for the lysophospholipid growth factors lysophosphatidic acid and sphingosine 1-phosphate

    Edward J. Goetzl;Songzhu An

  • Matrix metalloproteinases in immunity.

    E J Goetzl;M J Banda;D Leppert

  • The immunosuppressant FTY720 down-regulates sphingosine 1-phosphate G-protein-coupled receptors

    Markus H. Gräler;Edward J. Goetzl

  • International Union of Pharmacology. XXXIV. Lysophospholipid Receptor Nomenclature

    Jerold Chun;Edward J. Goetzl;Timothy Hla;Yasuyuki Igarashi

  • Molecular and cellular mechanisms of leukocyte chemotaxis.

    Ralph Snyderman;Edward J. Goetzl

  • O3-induced change in bronchial reactivity to methacholine and airway inflammation in humans

    J. Seltzer;B. G. Bigby;M. Stulbarg;M. J. Holtzman

  • Altered lysosomal proteins in neural-derived plasma exosomes in preclinical Alzheimer disease

    Edward J. Goetzl;Adam Boxer;Janice B. Schwartz;Erin L. Abner

  • Stimulation of human eosinophil and neutrophil polymorphonuclear leukocyte chemotaxis and random migration by 12-L-hydroxy-5,8,10,14-eicosatetraenoic acid.

    Edward J. Goetzl;Janet M. Woods;Robert R. Gorman

  • Plasma Extracellular Vesicles Enriched for Neuronal Origin: A Potential Window into Brain Pathologic Processes.

    Maja Mustapic;Erez Eitan;John K. Werner;John K. Werner;Sean T. Berkowitz

  • Leukotriene B4 produces hyperalgesia that is dependent on polymorphonuclear leukocytes.

    Jon D. Levine;Wai Lau;Geoffrey Kwiat;Edward J. Goetzl

  • Identification of cDNAs encoding two G protein‐coupled receptors for lysosphingolipids

    Songzhu An;Thieu Bleu;Wei Huang;Olivia G Hallmark

  • Human neutrophil chemotactic and degranulating activities of leukotriene B5 (LTB5) derived from eicosapentaenoic acid

    D.W. Goldman;D.W. Goldman;W.C. Pickett;E.J. Goetzl;E.J. Goetzl

  • Specificity of expression and effects of eicosanoid mediators in normal physiology and human diseases.

    Edward J. Goetzl;Sonczhu An;William L. Smith

  • Molecular Cloning of the Human Edg2 Protein and Its Identification as a Functional Cellular Receptor for Lysophosphatidic Acid

    An S;Dickens Ma;Bleu T;Hallmark Og

  • Substance P recognition by a subset of human T lymphocytes.

    D G Payan;D R Brewster;A Missirian-Bastian;E J Goetzl

  • Lysophosphatidic Acid Induction of Vascular Endothelial Growth Factor Expression in Human Ovarian Cancer Cells

    Yu Long Hu;Meng Kian Tee;Edward J. Goetzl;Nelly Auersperg

  • Predominant generation of 15-lipoxygenase metabolites of arachidonic acid by epithelial cells from human trachea.

    J A Hunter;W E Finkbeiner;J A Nadel;E J Goetzl

Frequent Co-Authors

Dimitrios Kapogiannis
Dimitrios Kapogiannis National Institutes of Health
Bruce L. Miller
Bruce L. Miller University of California, San Francisco
Menghang Xia
Menghang Xia National Institutes of Health
Christoph W. Turck
Christoph W. Turck Max Planck Society
K. Frank Austen
K. Frank Austen Brigham and Women's Hospital
Donald G. Payan
Donald G. Payan Sunesis (United States)
Stephen I. Wasserman
Stephen I. Wasserman University of California, San Diego
Jon D. Levine
Jon D. Levine University of California, San Francisco
Ronald C. Petersen
Ronald C. Petersen University of Pennsylvania
Mark P. Mattson
Mark P. Mattson Johns Hopkins University

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