D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Molecular Biology D-index 71 Citations 21,547 109 World Ranking 833 National Ranking 458

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • RNA
  • Messenger RNA

Eukaryotic initiation factor, Internal ribosome entry site, Initiation factor, Eukaryotic translation and Cell biology are his primary areas of study. His Eukaryotic initiation factor research is multidisciplinary, relying on both eIF2, EIF1, EIF4G, Eukaryotic Small Ribosomal Subunit and Eukaryotic Ribosome. In his study, which falls under the umbrella issue of Initiation factor, Untranslated region and Start codon is strongly linked to Transfer RNA.

His Eukaryotic translation study combines topics in areas such as Molecular biology and eIF4A. His Molecular biology study combines topics from a wide range of disciplines, such as Eukaryotic translation initiation factor 4 gamma, Ribosome, RNA, Hepatitis C virus internal ribosome entry site and Picornavirus. His Cell biology study which covers Eukaryotic initiation factor 4F that intersects with Five prime untranslated region.

His most cited work include:

  • The mechanism of eukaryotic translation initiation and principles of its regulation (1757 citations)
  • Internal ribosome entry sites in eukaryotic mRNA molecules (873 citations)
  • A prokaryotic-like mode of cytoplasmic eukaryotic ribosome binding to the initiation codon during internal translation initation of hepatitis C and classical swine fever virus RNAs (652 citations)

What are the main themes of his work throughout his whole career to date?

His main research concerns Eukaryotic initiation factor, Cell biology, Eukaryotic translation, Internal ribosome entry site and Initiation factor. His research in Eukaryotic initiation factor intersects with topics in eIF2, EIF4G, EIF1, Molecular biology and Eukaryotic Small Ribosomal Subunit. His biological study spans a wide range of topics, including A-site and Translation, EIF4E, Messenger RNA, Eukaryotic Ribosome.

His study explores the link between Eukaryotic translation and topics such as Eukaryotic translation initiation factor 4 gamma that cross with problems in EIF4A1. His studies in Internal ribosome entry site integrate themes in fields like Ribosomal binding site, Picornavirus and eIF4A. Within one scientific family, he focuses on topics pertaining to Prokaryotic initiation factor under Initiation factor, and may sometimes address concerns connected to Translational regulation.

He most often published in these fields:

  • Eukaryotic initiation factor (54.95%)
  • Cell biology (52.25%)
  • Eukaryotic translation (48.65%)

What were the highlights of his more recent work (between 2013-2021)?

  • Cell biology (52.25%)
  • Ribosome (29.73%)
  • Internal ribosome entry site (48.65%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are Cell biology, Ribosome, Internal ribosome entry site, Initiation factor and Eukaryotic Ribosome. His Cell biology research includes themes of Exosome complex, RNA, Transfer RNA, Eukaryotic Small Ribosomal Subunit and Messenger RNA. His studies deal with areas such as Eukaryotic translation, Protein subunit and EIF4E as well as Eukaryotic Small Ribosomal Subunit.

The Internal ribosome entry site study combines topics in areas such as Nucleic acid structure, Eukaryotic initiation factor, EIF4G and Start codon. His work in Eukaryotic initiation factor is not limited to one particular discipline; it also encompasses Molecular biology. Christopher U.T. Hellen interconnects eIF4A, eIF2, EIF1 and Virology in the investigation of issues within EIF4G.

Between 2013 and 2021, his most popular works were:

  • Structure of mammalian eIF3 in the context of the 43S preinitiation complex (139 citations)
  • Inhibition of translation by IFIT family members is determined by their ability to interact selectively with the 5′-terminal regions of cap0-, cap1- and 5′ppp- mRNAs (111 citations)
  • The mechanism of translation initiation on Type 1 picornavirus IRESs (95 citations)

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

The mechanism of eukaryotic translation initiation and principles of its regulation

Richard J. Jackson;Christopher U. T. Hellen;Tatyana V. Pestova.
Nature Reviews Molecular Cell Biology (2010)

2741 Citations

Internal ribosome entry sites in eukaryotic mRNA molecules

Christopher U.T. Hellen;Peter Sarnow.
Genes & Development (2001)

1416 Citations

Molecular mechanisms of translation initiation in eukaryotes.

Tatyana V. Pestova;Victoria G. Kolupaeva;Ivan B. Lomakin;Evgeny V. Pilipenko.
Proceedings of the National Academy of Sciences of the United States of America (2001)

976 Citations

A prokaryotic-like mode of cytoplasmic eukaryotic ribosome binding to the initiation codon during internal translation initation of hepatitis C and classical swine fever virus RNAs

Tatyana V. Pestova;Ivan N. Shatsky;Simon P. Fletcher;Richard J. Jackson.
Genes & Development (1998)

899 Citations

Genetics of poliovirus.

Eckard Wimmer;Christopher U. T. Hellen;Xuemei Cao.
Annual Review of Genetics (1993)

743 Citations

Canonical eukaryotic initiation factors determine initiation of translation by internal ribosomal entry

T. V. Pestova;C. U. T. Hellen;I. N. Shatsky.
Molecular and Cellular Biology (1996)

627 Citations

Eukaryotic ribosomes require initiation factors 1 and 1A to locate initiation codons

Tatyana V. Pestova;Tatyana V. Pestova;Sergei I. Borukhov;Christopher U. T. Hellen.
Nature (1998)

525 Citations

The joining of ribosomal subunits in eukaryotes requires eIF5B

Tatyana V. Pestova;Ivan B. Lomakin;Joon H. Lee;Sang Ki Choi.
Nature (2000)

517 Citations

Functional dissection of eukaryotic initiation factor 4F: the 4A subunit and the central domain of the 4G subunit are sufficient to mediate internal entry of 43S preinitiation complexes.

T. V. Pestova;I. N. Shatsky;C. U. T. Hellen.
Molecular and Cellular Biology (1996)

505 Citations

Initiation of protein synthesis from the A site of the ribosome.

Joan E Wilson;Tatyana V Pestova;Christopher U.T Hellen;Peter Sarnow.
Cell (2000)

480 Citations

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