Eukaryotic initiation factor, Internal ribosome entry site, Initiation factor, Eukaryotic translation and Cell biology are his primary areas of study. His Eukaryotic initiation factor research is multidisciplinary, relying on both eIF2, EIF1, EIF4G, Eukaryotic Small Ribosomal Subunit and Eukaryotic Ribosome. In his study, which falls under the umbrella issue of Initiation factor, Untranslated region and Start codon is strongly linked to Transfer RNA.
His Eukaryotic translation study combines topics in areas such as Molecular biology and eIF4A. His Molecular biology study combines topics from a wide range of disciplines, such as Eukaryotic translation initiation factor 4 gamma, Ribosome, RNA, Hepatitis C virus internal ribosome entry site and Picornavirus. His Cell biology study which covers Eukaryotic initiation factor 4F that intersects with Five prime untranslated region.
His main research concerns Eukaryotic initiation factor, Cell biology, Eukaryotic translation, Internal ribosome entry site and Initiation factor. His research in Eukaryotic initiation factor intersects with topics in eIF2, EIF4G, EIF1, Molecular biology and Eukaryotic Small Ribosomal Subunit. His biological study spans a wide range of topics, including A-site and Translation, EIF4E, Messenger RNA, Eukaryotic Ribosome.
His study explores the link between Eukaryotic translation and topics such as Eukaryotic translation initiation factor 4 gamma that cross with problems in EIF4A1. His studies in Internal ribosome entry site integrate themes in fields like Ribosomal binding site, Picornavirus and eIF4A. Within one scientific family, he focuses on topics pertaining to Prokaryotic initiation factor under Initiation factor, and may sometimes address concerns connected to Translational regulation.
His primary areas of study are Cell biology, Ribosome, Internal ribosome entry site, Initiation factor and Eukaryotic Ribosome. His Cell biology research includes themes of Exosome complex, RNA, Transfer RNA, Eukaryotic Small Ribosomal Subunit and Messenger RNA. His studies deal with areas such as Eukaryotic translation, Protein subunit and EIF4E as well as Eukaryotic Small Ribosomal Subunit.
The Internal ribosome entry site study combines topics in areas such as Nucleic acid structure, Eukaryotic initiation factor, EIF4G and Start codon. His work in Eukaryotic initiation factor is not limited to one particular discipline; it also encompasses Molecular biology. Christopher U.T. Hellen interconnects eIF4A, eIF2, EIF1 and Virology in the investigation of issues within EIF4G.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
The mechanism of eukaryotic translation initiation and principles of its regulation
Richard J. Jackson;Christopher U. T. Hellen;Tatyana V. Pestova.
Nature Reviews Molecular Cell Biology (2010)
Internal ribosome entry sites in eukaryotic mRNA molecules
Christopher U.T. Hellen;Peter Sarnow.
Genes & Development (2001)
Molecular mechanisms of translation initiation in eukaryotes.
Tatyana V. Pestova;Victoria G. Kolupaeva;Ivan B. Lomakin;Evgeny V. Pilipenko.
Proceedings of the National Academy of Sciences of the United States of America (2001)
A prokaryotic-like mode of cytoplasmic eukaryotic ribosome binding to the initiation codon during internal translation initation of hepatitis C and classical swine fever virus RNAs
Tatyana V. Pestova;Ivan N. Shatsky;Simon P. Fletcher;Richard J. Jackson.
Genes & Development (1998)
Genetics of poliovirus.
Eckard Wimmer;Christopher U. T. Hellen;Xuemei Cao.
Annual Review of Genetics (1993)
Canonical eukaryotic initiation factors determine initiation of translation by internal ribosomal entry
T. V. Pestova;C. U. T. Hellen;I. N. Shatsky.
Molecular and Cellular Biology (1996)
Eukaryotic ribosomes require initiation factors 1 and 1A to locate initiation codons
Tatyana V. Pestova;Tatyana V. Pestova;Sergei I. Borukhov;Christopher U. T. Hellen.
Nature (1998)
The joining of ribosomal subunits in eukaryotes requires eIF5B
Tatyana V. Pestova;Ivan B. Lomakin;Joon H. Lee;Sang Ki Choi.
Nature (2000)
Functional dissection of eukaryotic initiation factor 4F: the 4A subunit and the central domain of the 4G subunit are sufficient to mediate internal entry of 43S preinitiation complexes.
T. V. Pestova;I. N. Shatsky;C. U. T. Hellen.
Molecular and Cellular Biology (1996)
Initiation of protein synthesis from the A site of the ribosome.
Joan E Wilson;Tatyana V Pestova;Christopher U.T Hellen;Peter Sarnow.
Cell (2000)
If you think any of the details on this page are incorrect, let us know.
We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:
SUNY Downstate Medical Center
Stony Brook University
Lomonosov Moscow State University
Harvard University
Columbia University
Cleveland State University
University of Liverpool
Stanford University
Rutgers, The State University of New Jersey
McGill University
University of Minnesota
Colorado State University
University of Tennessee at Knoxville
Royal Veterinary College
University of Ottawa
Chinese Academy of Sciences
James Cook University
Max Planck Society
Met Office
University of Michigan–Ann Arbor
University of Vienna
Columbia University
Vanderbilt University Medical Center
University of Campania "Luigi Vanvitelli"
University of Illinois at Chicago
National Institute for Nuclear Physics