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Molecular Biology

D-Index
48
Citations
9548
World Ranking
2679
National Ranking
4

Research.com Recognitions

  • 2012 - Member of Academia Europaea

Overview

Ivan N. Shatsky is affiliated with Lomonosov Moscow State University in the Russian Federation. Their research primarily falls within the field of Biochemistry, Genetics and Molecular Biology, with a substantial focus on Molecular Biology as a subfield. The scientist's work encompasses several specialized research topics including RNA and protein synthesis mechanisms, RNA modifications and cancer, RNA research and splicing, molecular biology techniques and applications, CRISPR and genetic engineering, genomics and phylogenetic studies, and viral infections and immunology research.

Recent publications by Ivan N. Shatsky cover various aspects of translation initiation and RNA biology. These include:

  • Non-AUG translation initiation in mammals, 2022, published in Genome Biology
  • Unusually efficient CUG initiation of an overlapping reading frame in POLG mRNA yields novel protein POLGARF, 2020, Proceedings of the National Academy of Sciences
  • Ribosomal leaky scanning through a translated uORF requires eIF4G2, 2021, Nucleic Acids Research
  • Specific mechanisms of translation initiation in higher eukaryotes: the eIF4G2 story, 2022, RNA
  • Guidelines for minimal reporting requirements, design and interpretation of experiments involving the use of eukaryotic dual gene expression reporters (MINDR), 2025, Nature Structural & Molecular Biology

The scientist has collaborated frequently with several researchers including Dmitry E. Andreev, Ilya M. Terenin, Gary Loughran, Pavel V. Baranov, and Ekaterina D. Shestakova. These collaborations have contributed to the breadth and depth of their work in molecular biology and related fields.

Ivan N. Shatsky's publications appear in diverse venues, with multiple works published in the International Journal of Molecular Sciences, as well as contributions to Genome Biology, Nature Structural & Molecular Biology, Proceedings of the National Academy of Sciences, and Nucleic Acids Research.

Award recognition includes their membership in Academia Europaea, which was conferred in 2012.

Best Publications

  • Molecular mechanisms of translation initiation in eukaryotes.

    Tatyana V. Pestova;Victoria G. Kolupaeva;Ivan B. Lomakin;Evgeny V. Pilipenko

  • A prokaryotic-like mode of cytoplasmic eukaryotic ribosome binding to the initiation codon during internal translation initation of hepatitis C and classical swine fever virus RNAs

    Tatyana V. Pestova;Ivan N. Shatsky;Simon P. Fletcher;Richard J. Jackson

  • Canonical eukaryotic initiation factors determine initiation of translation by internal ribosomal entry

    T. V. Pestova;C. U. T. Hellen;I. N. Shatsky

  • Functional dissection of eukaryotic initiation factor 4F: the 4A subunit and the central domain of the 4G subunit are sufficient to mediate internal entry of 43S preinitiation complexes.

    T. V. Pestova;I. N. Shatsky;C. U. T. Hellen

  • Specific interaction of eukaryotic translation initiation factor 3 with the 5' nontranslated regions of hepatitis C virus and classical swine fever virus RNAs.

    Daria V. Sizova;Victoria G. Kolupaeva;Victoria G. Kolupaeva;Tatyana V. Pestova;Tatyana V. Pestova;Ivan N. Shatsky

  • Lipoxygenase mRNA silencing in erythroid differentiation: The 3'UTR regulatory complex controls 60S ribosomal subunit joining.

    Dirk H Ostareck;Antje Ostareck-Lederer;Ivan N Shatsky;Matthias W Hentze

  • Translation of 5' leaders is pervasive in genes resistant to eIF2 repression

    Dmitry E Andreev;Patrick B F O'Connor;Ciara Fahey;Elaine M Kenny

  • Translation Eukaryotic Initiation Factor 4G Recognizes a Specific Structural Element within the Internal Ribosome Entry Site of Encephalomyocarditis Virus RNA

    Victoria G. Kolupaeva;Victoria G. Kolupaeva;Tatyana V. Pestova;Tatyana V. Pestova;Christopher U.T. Hellen;Ivan N. Shatsky

  • Eukaryotic translation initiation machinery can operate in a bacterial-like mode without eIF2.

    Ilya M Terenin;Sergey E Dmitriev;Dmitry E Andreev;Ivan N Shatsky

  • GTP-independent tRNA Delivery to the Ribosomal P-site by a Novel Eukaryotic Translation Factor

    Sergey E. Dmitriev;Ilya M. Terenin;Dmitri E. Andreev;Pavel A. Ivanov

  • PSF acts through the human immunodeficiency virus type 1 mRNA instability elements to regulate virus expression.

    Andrei S. Zolotukhin;Daniel Michalowski;Jenifer Bear;Sergey V. Smulevitch

  • Efficient Translation Initiation Directed by the 900-Nucleotide-Long and GC-Rich 5 Untranslated Region of the Human Retrotransposon LINE-1 mRNA Is Strictly Cap Dependent Rather than Internal Ribosome Entry Site Mediated

    Sergey E. Dmitriev;Dmitri E. Andreev;Ilya M. Terenin;Ivan A. Olovnikov

  • Structural analysis of the interaction of the pyrimidine tract-binding protein with the internal ribosomal entry site of encephalomyocarditis virus and foot-and-mouth disease virus RNAs.

    V G Kolupaeva;C U Hellen;I N Shatsky

  • Insights into the mechanisms of eukaryotic translation gained with ribosome profiling.

    Dmitry E. Andreev;Patrick B. F. O'Connor;Gary Loughran;Sergey E. Dmitriev

  • Functional and Structural Similarities between the Internal Ribosome Entry Sites of Hepatitis C Virus and Porcine Teschovirus, a Picornavirus

    Andrey V. Pisarev;Louisa S. Chard;Yoshihiro Kaku;Helen L. Johns

  • Cap- and IRES-independent scanning mechanism of translation initiation as an alternative to the concept of cellular IRESs.

    Ivan N. Shatsky;Sergey E. Dmitriev;Ilya M. Terenin;D.E. Andreev

  • Oxygen and glucose deprivation induces widespread alterations in mRNA translation within 20 minutes

    Dmitry E Andreev;Dmitry E Andreev;Patrick B F O'Connor;Alexander V Zhdanov;Ruslan I Dmitriev

  • Distinctive Properties of the 5′-Untranslated Region of Human Hsp70 mRNA

    Maria P. Rubtsova;Daria V. Sizova;Sergei E. Dmitriev;Dmitri S. Ivanov

  • Cap-Independent Translation: What's in a Name?

    Ivan N. Shatsky;Ilya M. Terenin;Victoria V. Smirnova;Dmitri E. Andreev

  • Assembly of 48S Translation Initiation Complexes from Purified Components with mRNAs That Have Some Base Pairing within Their 5′ Untranslated Regions

    Sergei E. Dmitriev;Ilya M. Terenin;Yan E. Dunaevsky;William C. Merrick

Frequent Co-Authors

Tatyana V. Pestova
Tatyana V. Pestova SUNY Downstate Medical Center
Christopher U.T. Hellen
Christopher U.T. Hellen SUNY Downstate Medical Center
William C. Merrick
William C. Merrick Case Western Reserve University
Dmitri B. Papkovsky
Dmitri B. Papkovsky University College Cork
Graham J. Belsham
Graham J. Belsham University of Copenhagen
Derek W. Morris
Derek W. Morris University of Galway
John F. Atkins
John F. Atkins University College Cork
Dieter Glebe
Dieter Glebe University of Giessen
Vadim I. Agol
Vadim I. Agol Lomonosov Moscow State University
Alexander Goesmann
Alexander Goesmann University of Giessen

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