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Yuri V. Svitkin

Yuri V. Svitkin

D-Index & Metrics

Biology and Biochemistry

D-Index
58
Citations
14819
World Ranking
13020
National Ranking
442

Overview

Yuri V. Svitkin is affiliated with McGill University in Canada and has contributed to the fields of Biochemistry, Genetics and Molecular Biology, as well as Medicine. Their main research areas include Molecular Biology, Cardiology and Cardiovascular Medicine, Infectious Diseases, Epidemiology, and Genetics.

Their work broadly covers topics such as RNA and protein synthesis mechanisms, Viral Infections and Immunology Research, Viral gastroenteritis research and epidemiology, Cervical Cancer and HPV Research, Virus-based gene therapy research, RNA Research and Splicing, and RNA regulation and disease.

Recent publications by Yuri V. Svitkin include:

  • Membrane-dependent relief of translation elongation arrest on pseudouridine- and N1-methyl-pseudouridine-modified mRNAs (2021, Nucleic Acids Research)
  • High-risk human papillomavirus-18 uses an mRNA sequence to synthesize oncoprotein E6 in tumors (2021, Proceedings of the National Academy of Sciences)
  • ITAF 45 is a pervasive trans-acting factor for picornavirus Type II IRES elements (2025, Proceedings of the National Academy of Sciences)
  • Alexander Spirin (1931-2020): A visionary scientist, a teacher, a colleague, a friend (2021, Proceedings of the National Academy of Sciences)

Frequent coauthors collaborating with Svitkin include:

  • Nahum Sonenberg
  • Anne-Claude Gingras
  • Alejandra García
  • Giovanna Maldonado
  • José L. González

The scientist's work is often published in the following venues:

  • Proceedings of the National Academy of Sciences
  • Nucleic Acids Research

Best Publications

  • Rapamycin blocks the phosphorylation of 4E-BP1 and inhibits cap-dependent initiation of translation.

    Laura Beretta;Anne Claude Gingras;Yuri V. Svitkin;Michael N. Hall

  • MicroRNA inhibition of translation initiation in vitro by targeting the cap-binding complex eIF4F

    Géraldine Mathonnet;Marc R. Fabian;Yuri V. Svitkin;Armen Parsyan

  • Mammalian poly(A)-binding protein is a eukaryotic translation initiation factor, which acts via multiple mechanisms

    Avak Kahvejian;Yuri V. Svitkin;Rami Sukarieh;Marie-Noël M'Boutchou

  • La autoantigen enhances and corrects aberrant translation of poliovirus RNA in reticulocyte lysate.

    K. Meerovitch;Y. V. Svitkin;H. S. Lee;F. Lejbkowicz

  • The requirement for eukaryotic initiation factor 4A (elF4A) in translation is in direct proportion to the degree of mRNA 5' secondary structure.

    Yuri V. Svitkin;Arnim Pause;Ashkan Haghighat;Stéphane Pyronnet

  • Mammalian miRNA RISC Recruits CAF1 and PABP to Affect PABP-Dependent Deadenylation

    Marc R. Fabian;Géraldine Mathonnet;Thomas Sundermeier;Hansruedi Mathys

  • Dominant negative mutants of mammalian translation initiation factor eIF-4A define a critical role for eIF-4F in cap-dependent and cap-independent initiation of translation.

    Arnim Pause;Nathalie Méthot;Yuri Svitkin;William C. Merrick

  • Proteolysis of human eukaryotic translation initiation factor eIF4GII, but not eIF4GI, coincides with the shutoff of host protein synthesis after poliovirus infection

    Alessandra Gradi;Yuri V. Svitkin;Hiroaki Imataka;Nahum Sonenberg

  • Cap and cap-binding proteins in the control of gene expression.

    Ivan Topisirovic;Yuri V. Svitkin;Nahum Sonenberg;Aaron J. Shatkin

  • A Novel Functional Human Eukaryotic Translation Initiation Factor 4G

    Alessandra Gradi;Hiroaki Imataka;Yuri V. Svitkin;Eran Rom

  • mRNA helicases:the tacticians of translational control

    Armen Parsyan;Yuri Svitkin;David Shahbazian;Christos Gkogkas

  • Translational control of the innate immune response through IRF-7

    Rodney Colina;Mauro Costa-Mattioli;Ryan J. O. Dowling;Maritza Jaramillo

  • The major mRNA‐associated protein YB‐1 is a potent 5′ cap‐dependent mRNA stabilizer

    Valentina Evdokimova;Valentina Evdokimova;Peter Ruzanov;Peter Ruzanov;Hiroaki Imataka;Brian Raught

  • Prokaryotic-like cis elements in the cap-independent internal initiation of translation on picornavirus RNA.

    Evgeny V. Pilipenko;Anatoly P. Gmyl;Svetlana V. Maslova;Yuri V. Svitkin

  • Activation of the translational suppressor 4E-BP1 following infection with encephalomyocarditis virus and poliovirus.

    Anne-Claude Gingras;Yuri Svitkin;Graham J. Belsham;Arnim Pause

  • Eukaryotic translation initiation factor 4E (eIF4E) binding site and the middle one-third of eIF4GI constitute the core domain for cap-dependent translation, and the C-terminal one-third functions as a modulatory region.

    Shigenobu Morino;Hiroaki Imataka;Yuri V. Svitkin;Tatyana V. Pestova

  • Translational Repression by a Novel Partner of Human Poly(A) Binding Protein, Paip2

    Kianoush Khaleghpour;Yuri V Svitkin;Andrew W Craig;Christine T DeMaria

  • La-related Protein 1 (LARP1) Represses Terminal Oligopyrimidine (TOP) mRNA Translation Downstream of mTOR Complex 1 (mTORC1)

    Bruno D. Fonseca;Chadi Zakaria;Jian Jun Jia;Tyson E. Graber

  • Eukaryotic Translation Initiation Factor 4E Availability Controls the Switch between Cap-Dependent and Internal Ribosomal Entry Site-Mediated Translation

    Yuri V. Svitkin;Barbara Herdy;Mauro Costa-Mattioli;Anne-Claude Gingras

  • General RNA binding proteins render translation cap dependent.

    Y V Svitkin;L P Ovchinnikov;G Dreyfuss;N Sonenberg

Frequent Co-Authors

Nahum Sonenberg
Nahum Sonenberg McGill University
Vadim I. Agol
Vadim I. Agol Lomonosov Moscow State University
Graham J. Belsham
Graham J. Belsham University of Copenhagen
Arnim Pause
Arnim Pause McGill University
Anne-Claude Gingras
Anne-Claude Gingras Lunenfeld-Tanenbaum Research Institute
Tatyana V. Pestova
Tatyana V. Pestova SUNY Downstate Medical Center
Ivan Topisirovic
Ivan Topisirovic McGill University
William C. Merrick
William C. Merrick Case Western Reserve University
Jerry Pelletier
Jerry Pelletier McGill University
Brian Raught
Brian Raught Princess Margaret Cancer Centre

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