His primary areas of investigation include Eukaryotic initiation factor, Eukaryotic translation, Cell biology, Initiation factor and Internal ribosome entry site. As part of his Genetics and Biochemistry and Eukaryotic initiation factor studies, Yuri V. Svitkin is studying Eukaryotic initiation factor. His Eukaryotic translation research incorporates themes from RNA, Ribosome and Protein biosynthesis.
His work carried out in the field of Protein biosynthesis brings together such families of science as Poliovirus and Virology. His biological study spans a wide range of topics, including Translation and Molecular biology. His Internal ribosome entry site research focuses on subjects like EIF4E, which are linked to Rotavirus translation.
Yuri V. Svitkin mainly focuses on Translation, Molecular biology, EIF4E, Cell biology and Protein biosynthesis. Within one scientific family, Yuri V. Svitkin focuses on topics pertaining to RNA under Translation, and may sometimes address concerns connected to Virus and Virology. As part of one scientific family, Yuri V. Svitkin deals mainly with the area of Molecular biology, narrowing it down to issues related to the Gene expression, and often P-bodies.
His research integrates issues of Five prime untranslated region, Eukaryotic Initiation Factor-4E, Eukaryotic initiation factor and EIF4G in his study of EIF4E. The study incorporates disciplines such as Eukaryotic translation initiation factor 4 gamma, Eukaryotic translation, eIF4A and Initiation factor in addition to Eukaryotic initiation factor. His Cell biology research integrates issues from Poly-binding protein, Binding protein, Cap binding complex, microRNA and Repressor.
Yuri V. Svitkin focuses on Cell biology, EIF4E, Translation, Molecular biology and Eukaryotic translation. His research in Cell biology intersects with topics in In vitro, Gene expression, P-bodies, Messenger RNA and Initiation factor. Yuri V. Svitkin interconnects Five prime untranslated region and Internal ribosome entry site in the investigation of issues within Initiation factor.
His studies in Translation integrate themes in fields like Proteasome inhibitor, Cell culture and Protein biosynthesis. His work investigates the relationship between Molecular biology and topics such as Eukaryotic Initiation Factor-4E that intersect with problems in EIF4EBP1. His Eukaryotic translation study integrates concerns from other disciplines, such as Eukaryotic initiation factor, Ribosome and eIF4A.
Yuri V. Svitkin focuses on EIF4E, Molecular biology, Eukaryotic initiation factor, Cell biology and Translational regulation. His EIF4E research includes elements of Repressor and Protein biosynthesis. His work deals with themes such as NF-κB, IκBα, Phosphorylation and Five-prime cap, which intersect with Molecular biology.
The various areas that Yuri V. Svitkin examines in his Eukaryotic initiation factor study include Initiation factor, Five prime untranslated region, Eukaryotic translation initiation factor 4 gamma and Eukaryotic translation. His study in Cell biology is interdisciplinary in nature, drawing from both P-bodies, Rotavirus translation, Cap binding complex and Gene expression. His Translational regulation study combines topics from a wide range of disciplines, such as Ubiquitin, Gene knockdown, Internal ribosome entry site, eIF4A and Eukaryotic Ribosome.
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Rapamycin blocks the phosphorylation of 4E-BP1 and inhibits cap-dependent initiation of translation.
Laura Beretta;Anne Claude Gingras;Yuri V. Svitkin;Michael N. Hall.
The EMBO Journal (1996)
MicroRNA inhibition of translation initiation in vitro by targeting the cap-binding complex eIF4F
Géraldine Mathonnet;Marc R. Fabian;Yuri V. Svitkin;Armen Parsyan.
La autoantigen enhances and corrects aberrant translation of poliovirus RNA in reticulocyte lysate.
K. Meerovitch;Y. V. Svitkin;H. S. Lee;F. Lejbkowicz.
Journal of Virology (1993)
Mammalian poly(A)-binding protein is a eukaryotic translation initiation factor, which acts via multiple mechanisms
Avak Kahvejian;Yuri V. Svitkin;Rami Sukarieh;Marie-Noël M'Boutchou.
Genes & Development (2005)
The requirement for eukaryotic initiation factor 4A (elF4A) in translation is in direct proportion to the degree of mRNA 5' secondary structure.
Yuri V. Svitkin;Arnim Pause;Ashkan Haghighat;Stéphane Pyronnet.
Mammalian miRNA RISC Recruits CAF1 and PABP to Affect PABP-Dependent Deadenylation
Marc R. Fabian;Géraldine Mathonnet;Thomas Sundermeier;Hansruedi Mathys.
Molecular Cell (2009)
Proteolysis of human eukaryotic translation initiation factor eIF4GII, but not eIF4GI, coincides with the shutoff of host protein synthesis after poliovirus infection
Alessandra Gradi;Yuri V. Svitkin;Hiroaki Imataka;Nahum Sonenberg.
Proceedings of the National Academy of Sciences of the United States of America (1998)
Dominant negative mutants of mammalian translation initiation factor eIF-4A define a critical role for eIF-4F in cap-dependent and cap-independent initiation of translation.
Arnim Pause;Nathalie Méthot;Yuri Svitkin;William C. Merrick.
The EMBO Journal (1994)
A Novel Functional Human Eukaryotic Translation Initiation Factor 4G
Alessandra Gradi;Hiroaki Imataka;Yuri V. Svitkin;Eran Rom.
Molecular and Cellular Biology (1998)
Cap and cap-binding proteins in the control of gene expression.
Ivan Topisirovic;Yuri V. Svitkin;Nahum Sonenberg;Aaron J. Shatkin.
Wiley Interdisciplinary Reviews - Rna (2011)
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