D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 55 Citations 13,355 74 World Ranking 10330 National Ranking 354

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • RNA
  • Messenger RNA

His primary areas of investigation include Eukaryotic initiation factor, Eukaryotic translation, Cell biology, Initiation factor and Internal ribosome entry site. As part of his Genetics and Biochemistry and Eukaryotic initiation factor studies, Yuri V. Svitkin is studying Eukaryotic initiation factor. His Eukaryotic translation research incorporates themes from RNA, Ribosome and Protein biosynthesis.

His work carried out in the field of Protein biosynthesis brings together such families of science as Poliovirus and Virology. His biological study spans a wide range of topics, including Translation and Molecular biology. His Internal ribosome entry site research focuses on subjects like EIF4E, which are linked to Rotavirus translation.

His most cited work include:

  • Rapamycin blocks the phosphorylation of 4E-BP1 and inhibits cap-dependent initiation of translation. (611 citations)
  • MicroRNA inhibition of translation initiation in vitro by targeting the cap-binding complex eIF4F (452 citations)
  • La autoantigen enhances and corrects aberrant translation of poliovirus RNA in reticulocyte lysate. (413 citations)

What are the main themes of his work throughout his whole career to date?

Yuri V. Svitkin mainly focuses on Translation, Molecular biology, EIF4E, Cell biology and Protein biosynthesis. Within one scientific family, Yuri V. Svitkin focuses on topics pertaining to RNA under Translation, and may sometimes address concerns connected to Virus and Virology. As part of one scientific family, Yuri V. Svitkin deals mainly with the area of Molecular biology, narrowing it down to issues related to the Gene expression, and often P-bodies.

His research integrates issues of Five prime untranslated region, Eukaryotic Initiation Factor-4E, Eukaryotic initiation factor and EIF4G in his study of EIF4E. The study incorporates disciplines such as Eukaryotic translation initiation factor 4 gamma, Eukaryotic translation, eIF4A and Initiation factor in addition to Eukaryotic initiation factor. His Cell biology research integrates issues from Poly-binding protein, Binding protein, Cap binding complex, microRNA and Repressor.

He most often published in these fields:

  • Translation (45.33%)
  • Molecular biology (45.33%)
  • EIF4E (42.67%)

What were the highlights of his more recent work (between 2009-2021)?

  • Cell biology (40.00%)
  • EIF4E (42.67%)
  • Translation (45.33%)

In recent papers he was focusing on the following fields of study:

Yuri V. Svitkin focuses on Cell biology, EIF4E, Translation, Molecular biology and Eukaryotic translation. His research in Cell biology intersects with topics in In vitro, Gene expression, P-bodies, Messenger RNA and Initiation factor. Yuri V. Svitkin interconnects Five prime untranslated region and Internal ribosome entry site in the investigation of issues within Initiation factor.

His studies in Translation integrate themes in fields like Proteasome inhibitor, Cell culture and Protein biosynthesis. His work investigates the relationship between Molecular biology and topics such as Eukaryotic Initiation Factor-4E that intersect with problems in EIF4EBP1. His Eukaryotic translation study integrates concerns from other disciplines, such as Eukaryotic initiation factor, Ribosome and eIF4A.

Between 2009 and 2021, his most popular works were:

  • Cap and cap-binding proteins in the control of gene expression. (252 citations)
  • mRNA helicases:the tacticians of translational control (242 citations)
  • La-related Protein 1 (LARP1) Represses Terminal Oligopyrimidine (TOP) mRNA Translation Downstream of mTOR Complex 1 (mTORC1) (130 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • RNA
  • Messenger RNA

Yuri V. Svitkin focuses on EIF4E, Molecular biology, Eukaryotic initiation factor, Cell biology and Translational regulation. His EIF4E research includes elements of Repressor and Protein biosynthesis. His work deals with themes such as NF-κB, IκBα, Phosphorylation and Five-prime cap, which intersect with Molecular biology.

The various areas that Yuri V. Svitkin examines in his Eukaryotic initiation factor study include Initiation factor, Five prime untranslated region, Eukaryotic translation initiation factor 4 gamma and Eukaryotic translation. His study in Cell biology is interdisciplinary in nature, drawing from both P-bodies, Rotavirus translation, Cap binding complex and Gene expression. His Translational regulation study combines topics from a wide range of disciplines, such as Ubiquitin, Gene knockdown, Internal ribosome entry site, eIF4A and Eukaryotic Ribosome.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Rapamycin blocks the phosphorylation of 4E-BP1 and inhibits cap-dependent initiation of translation.

Laura Beretta;Anne Claude Gingras;Yuri V. Svitkin;Michael N. Hall.
The EMBO Journal (1996)

864 Citations

MicroRNA inhibition of translation initiation in vitro by targeting the cap-binding complex eIF4F

Géraldine Mathonnet;Marc R. Fabian;Yuri V. Svitkin;Armen Parsyan.
Science (2007)

743 Citations

La autoantigen enhances and corrects aberrant translation of poliovirus RNA in reticulocyte lysate.

K. Meerovitch;Y. V. Svitkin;H. S. Lee;F. Lejbkowicz.
Journal of Virology (1993)

624 Citations

Mammalian poly(A)-binding protein is a eukaryotic translation initiation factor, which acts via multiple mechanisms

Avak Kahvejian;Yuri V. Svitkin;Rami Sukarieh;Marie-Noël M'Boutchou.
Genes & Development (2005)

617 Citations

The requirement for eukaryotic initiation factor 4A (elF4A) in translation is in direct proportion to the degree of mRNA 5' secondary structure.

Yuri V. Svitkin;Arnim Pause;Ashkan Haghighat;Stéphane Pyronnet.
RNA (2001)

536 Citations

Mammalian miRNA RISC Recruits CAF1 and PABP to Affect PABP-Dependent Deadenylation

Marc R. Fabian;Géraldine Mathonnet;Thomas Sundermeier;Hansruedi Mathys.
Molecular Cell (2009)

493 Citations

Proteolysis of human eukaryotic translation initiation factor eIF4GII, but not eIF4GI, coincides with the shutoff of host protein synthesis after poliovirus infection

Alessandra Gradi;Yuri V. Svitkin;Hiroaki Imataka;Nahum Sonenberg.
Proceedings of the National Academy of Sciences of the United States of America (1998)

461 Citations

Dominant negative mutants of mammalian translation initiation factor eIF-4A define a critical role for eIF-4F in cap-dependent and cap-independent initiation of translation.

Arnim Pause;Nathalie Méthot;Yuri Svitkin;William C. Merrick.
The EMBO Journal (1994)

453 Citations

A Novel Functional Human Eukaryotic Translation Initiation Factor 4G

Alessandra Gradi;Hiroaki Imataka;Yuri V. Svitkin;Eran Rom.
Molecular and Cellular Biology (1998)

398 Citations

Cap and cap-binding proteins in the control of gene expression.

Ivan Topisirovic;Yuri V. Svitkin;Nahum Sonenberg;Aaron J. Shatkin.
Wiley Interdisciplinary Reviews - Rna (2011)

346 Citations

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