Eukaryotic initiation factor, Eukaryotic translation, Internal ribosome entry site, Initiation factor and Molecular biology are her primary areas of study. Her study in Eukaryotic initiation factor is interdisciplinary in nature, drawing from both EIF1 and EIF4G. Her Eukaryotic translation research incorporates elements of Eukaryotic Small Ribosomal Subunit, Biochemistry and eIF4A.
Her study looks at the relationship between Internal ribosome entry site and fields such as eIF2, as well as how they intersect with chemical problems. Her research integrates issues of Eukaryotic translation initiation factor 4 gamma and Cell biology in her study of Initiation factor. Tatyana V. Pestova has included themes like Ribosome, Hepatitis C virus internal ribosome entry site, Five prime untranslated region, EIF4E and Picornavirus in her Molecular biology study.
The scientist’s investigation covers issues in Eukaryotic initiation factor, Eukaryotic translation, Initiation factor, Internal ribosome entry site and Cell biology. Tatyana V. Pestova interconnects eIF2, EIF1, Molecular biology, Eukaryotic Small Ribosomal Subunit and Eukaryotic Ribosome in the investigation of issues within Eukaryotic initiation factor. Her Eukaryotic translation study combines topics from a wide range of disciplines, such as Eukaryotic translation initiation factor 4 gamma, GTPase, Biochemistry, Peptide Termination Factors and Biophysics.
Her Initiation factor research incorporates themes from Genetics, Prokaryotic initiation factor, Five prime untranslated region, Eukaryotic Initiation Factor-2 and EIF4A1. In her study, which falls under the umbrella issue of Internal ribosome entry site, Picornaviridae is strongly linked to Picornavirus. Her work carried out in the field of Cell biology brings together such families of science as Translation, EIF4E, Eukaryotic initiation factor 4F, EIF4G and Start codon.
Her primary areas of study are Cell biology, Ribosome, Initiation factor, Eukaryotic Ribosome and Internal ribosome entry site. Her biological study spans a wide range of topics, including eIF4A and Exosome complex. The concepts of her Ribosome study are interwoven with issues in Transfer RNA and GTPase.
Tatyana V. Pestova has researched Initiation factor in several fields, including Molecular biology, Eukaryotic translation, Eukaryotic initiation factor and Start codon. Her Eukaryotic initiation factor research includes elements of Eukaryotic Small Ribosomal Subunit, EIF1 and EIF4G. Her research investigates the connection with Internal ribosome entry site and areas like Genetics which intersect with concerns in Picornavirus and Viral evolution.
Tatyana V. Pestova spends much of her time researching Eukaryotic initiation factor, Initiation factor, Molecular biology, Ribosome and Transfer RNA. Her Initiation factor research integrates issues from Eukaryotic translation and Eukaryotic Small Ribosomal Subunit. Her research in Eukaryotic translation intersects with topics in Eukaryotic translation initiation factor 4 gamma, Rotavirus translation, Five prime untranslated region, Untranslated region and EIF4E.
Her Eukaryotic Small Ribosomal Subunit study integrates concerns from other disciplines, such as Eukaryotic Initiation Factor-2 and Cell biology. Her Molecular biology research is multidisciplinary, incorporating perspectives in Translation, Eukaryotic initiation factor 4F, Eukaryotic Initiation Factor-4E and RNA-binding protein. The various areas that Tatyana V. Pestova examines in her P-site study include Translation reinitiation, Ribosome Subunits, Internal ribosome entry site and Biochemistry, Protein biosynthesis.
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The mechanism of eukaryotic translation initiation and principles of its regulation
Richard J. Jackson;Christopher U. T. Hellen;Tatyana V. Pestova.
Nature Reviews Molecular Cell Biology (2010)
5′ UTR m6A Promotes Cap-Independent Translation
Kate D. Meyer;Deepak P. Patil;Jun Zhou;Alexandra Zinoviev.
Molecular mechanisms of translation initiation in eukaryotes.
Tatyana V. Pestova;Victoria G. Kolupaeva;Ivan B. Lomakin;Evgeny V. Pilipenko.
Proceedings of the National Academy of Sciences of the United States of America (2001)
A prokaryotic-like mode of cytoplasmic eukaryotic ribosome binding to the initiation codon during internal translation initation of hepatitis C and classical swine fever virus RNAs
Tatyana V. Pestova;Ivan N. Shatsky;Simon P. Fletcher;Richard J. Jackson.
Genes & Development (1998)
The roles of individual eukaryotic translation initiation factors in ribosomal scanning and initiation codon selection.
Tatyana V. Pestova;Victoria G. Kolupaeva.
Genes & Development (2002)
Canonical eukaryotic initiation factors determine initiation of translation by internal ribosomal entry
T. V. Pestova;C. U. T. Hellen;I. N. Shatsky.
Molecular and Cellular Biology (1996)
Eukaryotic ribosomes require initiation factors 1 and 1A to locate initiation codons
Tatyana V. Pestova;Tatyana V. Pestova;Sergei I. Borukhov;Christopher U. T. Hellen.
The joining of ribosomal subunits in eukaryotes requires eIF5B
Tatyana V. Pestova;Ivan B. Lomakin;Joon H. Lee;Sang Ki Choi.
Functional dissection of eukaryotic initiation factor 4F: the 4A subunit and the central domain of the 4G subunit are sufficient to mediate internal entry of 43S preinitiation complexes.
T. V. Pestova;I. N. Shatsky;C. U. T. Hellen.
Molecular and Cellular Biology (1996)
Initiation of protein synthesis from the A site of the ribosome.
Joan E Wilson;Tatyana V Pestova;Christopher U.T Hellen;Peter Sarnow.
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