What is he best known for?
The fields of study he is best known for:
Eukaryotic translation, Eukaryotic initiation factor, Biochemistry, Cell biology and Start codon are his primary areas of study.
While the research belongs to areas of Eukaryotic translation, Jon R. Lorsch spends his time largely on the problem of EIF1, intersecting his research to questions surrounding eIF2.
His Eukaryotic initiation factor research focuses on Initiation factor and how it relates to Prokaryotic initiation factor-2 and EIF4E.
His study in the field of Enzyme and Binding site is also linked to topics like Ribozyme, DEAD box and Protein domain.
His Cell biology study frequently links to adjacent areas such as Molecular biology.
His study connects Eukaryotic Small Ribosomal Subunit and Start codon.
His most cited work include:
- The molecular mechanics of eukaryotic translation (472 citations)
- The Mechanism of Eukaryotic Translation Initiation: New Insights and Challenges (317 citations)
- A mechanistic overview of translation initiation in eukaryotes (275 citations)
What are the main themes of his work throughout his whole career to date?
Jon R. Lorsch mainly investigates Eukaryotic translation, Eukaryotic initiation factor, Cell biology, Start codon and Biochemistry.
His Eukaryotic translation research includes themes of Translational regulation and Eukaryotic Small Ribosomal Subunit, Ribosome.
His work deals with themes such as eIF2, Five prime untranslated region, Eukaryotic Initiation Factor-2, Eukaryotic Ribosome and Initiation factor, which intersect with Eukaryotic initiation factor.
His Cell biology study often links to related topics such as Molecular biology.
In the subject of general Start codon, his work in EIF1 and Shine-Dalgarno sequence is often linked to Genetics, thereby combining diverse domains of study.
His study in the field of Protein biosynthesis, DNA and Binding site also crosses realms of Laboratory methods.
He most often published in these fields:
- Eukaryotic translation (47.24%)
- Eukaryotic initiation factor (40.16%)
- Cell biology (39.37%)
What were the highlights of his more recent work (between 2016-2020)?
- Cell biology (39.37%)
- Translation (20.47%)
- Start codon (33.07%)
In recent papers he was focusing on the following fields of study:
His primary areas of study are Cell biology, Translation, Start codon, Eukaryotic translation and eIF4A.
His study in the fields of Ribosome profiling under the domain of Translation overlaps with other disciplines such as Yeast.
His EIF1 study, which is part of a larger body of work in Start codon, is frequently linked to Genetics, bridging the gap between disciplines.
His research investigates the connection between Eukaryotic translation and topics such as Transfer RNA that intersect with issues in eIF2.
His research in eIF4A tackles topics such as EIF4E which are related to areas like EIF4G.
His work focuses on many connections between P-site and other disciplines, such as Eukaryotic initiation factor, that overlap with his field of interest in Ribosomal binding site.
Between 2016 and 2020, his most popular works were:
- eIF1A residues implicated in cancer stabilize translation preinitiation complexes and favor suboptimal initiation sites in yeast. (45 citations)
- Translational initiation factor eIF5 replaces eIF1 on the 40S ribosomal subunit to promote start-codon recognition. (37 citations)
- Rps3/uS3 promotes mRNA binding at the 40S ribosome entry channel and stabilizes preinitiation complexes at start codons. (32 citations)
In his most recent research, the most cited papers focused on:
Jon R. Lorsch spends much of his time researching Cell biology, Start codon, Ribosome, Translation and Untranslated region.
Jon R. Lorsch undertakes interdisciplinary study in the fields of Cell biology and Transcription preinitiation complex through his research.
His work on Ribosome is being expanded to include thematically relevant topics such as Eukaryotic translation.
In the field of Translation, his study on Ribosome profiling overlaps with subjects such as Context, Genetics, Chemical biology and Yeast.
As part of one scientific family, Jon R. Lorsch deals mainly with the area of Untranslated region, narrowing it down to issues related to the RNA Helicase A, and often Eukaryotic Ribosome.
His biological study spans a wide range of topics, including Transfer RNA, EIF1 and eIF2.
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