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Molecular Biology

D-Index
50
Citations
7789
World Ranking
2579
National Ranking
199

Overview

Martin Lowe is affiliated with the University of Manchester in the United Kingdom. Their research spans several interconnected fields within biochemistry, genetics, molecular biology, and medicine. The scientist's work has a significant focus on cell biology, molecular biology, physiology, surgery, and immunology.

Their research topics cover a range of areas including cellular transport and secretion, endoplasmic reticulum stress and disease, inflammasome and immune disorders, biomedical research and pathophysiology, pancreatic function and diabetes, retinal development and disorders, and heme oxygenase-1 and carbon monoxide.

Recent notable publications by Martin Lowe include:

  • The NLRP3-inflammasome as a sensor of organelle dysfunction (2020), The Journal of Cell Biology
  • Membrane trafficking in health and disease (2020), Disease Models & Mechanisms
  • PCYT2-regulated lipid biosynthesis is critical to muscle health and ageing (2023), Nature Metabolism
  • Disruptions in endocytic traffic contribute to the activation of the NLRP3 inflammasome (2023), Science Signaling
  • Cell-Based Phenotypic Drug Screening Identifies Luteolin as Candidate Therapeutic for Nephropathic Cystinosis (2020), Journal of the American Society of Nephrology

Martin Lowe frequently publishes in venues such as bioRxiv (Cold Spring Harbor Laboratory), The Journal of Cell Biology, Journal of Cell Science, Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature, and Disease Models & Mechanisms.

Their collaboration network includes frequent co-authorships with Rebecca Yarwood, Anthony Jackson-Crawford, Paula I. Seoane, David Brough, and Rachel Lennon.

Best Publications

  • A Role for Giantin in Docking COPI Vesicles to Golgi Membranes

    Birte Sönnichsen;Martin Lowe;Tim Levine;Eija Jämsä

  • The coiled-coil membrane protein golgin-84 is a novel rab effector required for Golgi ribbon formation

    Aipo Diao;Dinah Rahman;Darryl J.C. Pappin;John Lucocq

  • Caspase-mediated cleavage of the stacking protein GRASP65 is required for Golgi fragmentation during apoptosis.

    Jon D. Lane;John Lucocq;James Pryde;Francis A. Barr

  • Lowe Syndrome Protein OCRL1 Interacts with Clathrin and Regulates Protein Trafficking between Endosomes and the Trans-Golgi Network

    Rawshan Choudhury;Aipo Diao;Fang Zhang;Evan Eisenberg

  • The mitotic phosphorylation cycle of the cis-Golgi matrix protein GM130.

    Martin Lowe;Nicholas K. Gonatas;Graham Warren

  • Membrane targeting and activation of the Lowe syndrome protein OCRL1 by rab GTPases.

    Noora Hyvola;Aipo Diao;Eddie McKenzie;Alison Skippen

  • Structure and Function of the Lowe Syndrome Protein OCRL1

    Martin Lowe

  • Golgins and GRASPs: holding the Golgi together.

    Irene Barinaga-Rementeria Ramirez;Martin Lowe

  • The localization of human cyclins B1 and B2 determines CDK1 substrate specificity and neither enzyme requires MEK to disassemble the Golgi apparatus

    Viji Mythily Draviam;Simona Orrechia;Martin Lowe;Ruggero Pardi

  • Structural organization of the Golgi apparatus

    Martin Lowe

  • Autophagosome-lysosome fusion triggers a lysosomal response mediated by TLR9 and controlled by OCRL.

    Maria Giovanna De Leo;Leopoldo Staiano;Mariella Vicinanza;Alessandro Luciani

  • Inheritance and biogenesis of organelles in the secretory pathway

    Martin Lowe;Francis A. Barr

  • In Vitro Assembly and Disassembly of Coatomer

    Martin Lowe;Thomas E. Kreis

  • The Cellular and Physiological Functions of the Lowe Syndrome Protein OCRL1

    Zenobia B Mehta;Zenobia B Mehta;Grzegorz Pietka;Martin Lowe

  • Dissecting the role of the ARF guanine nucleotide exchange factor GBF1 in Golgi biogenesis and protein trafficking.

    Tomasz Szul;Robert Grabski;Susan Lyons;Yuichi Morohashi

  • Regulation of membrane traffic in animal cells by COPI.

    Martin Lowe;Thomas E. Kreis

  • Dissociation of Coatomer from Membranes Is Required for Brefeldin A–induced Transfer of Golgi Enzymes to the Endoplasmic Reticulum

    Jochen Scheel;Rainer Pepperkok;Martin Lowe;Gareth Griffiths

  • The Golgin Family of Coiled-Coil Tethering Proteins

    Tomasz M. Witkos;Martin Lowe

  • The NLRP3-inflammasome as a sensor of organelle dysfunction.

    Paula I. Seoane;Paula I. Seoane;Bali Lee;Bali Lee;Christopher Hoyle;Christopher Hoyle;Shi Yu;Shi Yu

  • Membrane trafficking in health and disease.

    Rebecca Yarwood;John Hellicar;Philip G. Woodman;Martin Lowe

Frequent Co-Authors

Francis A. Barr
Francis A. Barr University of Oxford
Uwe Kornak
Uwe Kornak University of Göttingen
Alexander A. Mironov
Alexander A. Mironov University of Manchester
Ralph R. Isberg
Ralph R. Isberg Tufts University
John M. Lucocq
John M. Lucocq University of St Andrews
Eija Jokitalo
Eija Jokitalo University of Helsinki
Timothy P. Levine
Timothy P. Levine University College London
Philip L. Beales
Philip L. Beales University College London
Stefan Mundlos
Stefan Mundlos Max Planck Society

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