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Microbiology

D-Index
60
Citations
11609
World Ranking
3157
National Ranking
234

Overview

Hubert Hilbi is affiliated with the University of Zurich in Switzerland. Their research primarily falls within the field of Biochemistry, Genetics and Molecular Biology, with significant contributions in related subfields such as Endocrinology, Molecular Biology, Immunology, Epidemiology, and Health, Toxicology and Mutagenesis.

The scientist's work focuses on several main topics, including:

  • Legionella and Acanthamoeba research
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • Bacterial biofilms and quorum sensing
  • Vibrio bacteria research studies
  • Water Treatment and Disinfection
  • Heme Oxygenase-1 and Carbon Monoxide
  • Autophagy in Disease and Therapy

Hubert Hilbi has been published frequently in a variety of scientific venues. The most common publication outlets include:

  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • bioRxiv (Cold Spring Harbor Laboratory)
  • mBio
  • Cellular Microbiology
  • EMBO Reports

Some of the recent papers associated with this researcher are:

  • Systematic exploration of Escherichia coli phage-host interactions with the BASEL phage collection, 2021, PLoS Biology
  • Bacterial quorum sensing and phenotypic heterogeneity: how the collective shapes the individual, 2021, Trends in Microbiology
  • The ABC transporter MsbA adopts the wide inward-open conformation in E. coli cells, 2022, Science Advances
  • Quorum sensing controls persistence, resuscitation, and virulence of Legionella subpopulations in biofilms, 2020, The ISME Journal
  • Phosphoinositides and the Fate of Legionella in Phagocytes, 2020, Frontiers in Immunology

Frequent collaborators in their research include:

  • Simone Vormittag
  • Dario Hüsler
  • A. Leoni Swart
  • Bianca Striednig
  • François Letourneur

Best Publications

  • Molecular Pathogenesis of Shigella spp.: Controlling Host Cell Signaling, Invasion, and Death by Type III Secretion

    Gunnar N. Schroeder;Hubert Hilbi

  • Shigella-induced Apoptosis Is Dependent on Caspase-1 Which Binds to IpaB

    Hubert Hilbi;Jeremy E. Moss;David Hersh;Yajing Chen

  • Legionella pneumophila exploits PI(4)P to anchor secreted effector proteins to the replicative vacuole.

    Stefan S Weber;Curdin Ragaz;Katrin Reus;Yves Nyfeler

  • Rab1 Guanine Nucleotide Exchange Factor SidM Is a Major Phosphatidylinositol 4-Phosphate-binding Effector Protein of Legionella pneumophila

    Eva Brombacher;Simon Urwyler;Curdin Ragaz;Stefan S. Weber

  • The Legionella pneumophila phosphatidylinositol-4 phosphate-binding type IV substrate SidC recruits endoplasmic reticulum vesicles to a replication-permissive vacuole

    Curdin Ragaz;Holger Pietsch;Simon Urwyler;André Tiaden

  • Systematic exploration of Escherichia coli phage-host interactions with the BASEL phage collection.

    Enea Maffei;Aisylu Shaidullina;Marco Burkolter;Yannik Heyer

  • IFNs Modify the Proteome of Legionella-Containing Vacuoles and Restrict Infection Via IRG1-Derived Itaconic Acid.

    Jan Naujoks;Christoph Tabeling;Brian D. Dill;Christine Hoffmann

  • Environmental predators as models for bacterial pathogenesis

    Hubert Hilbi;Stefan S. Weber;Curdin Ragaz;Yves Nyfeler

  • Legionella pneumophila Modulates Mitochondrial Dynamics to Trigger Metabolic Repurposing of Infected Macrophages

    Pedro Escoll;Ok-Ryul Song;Flávia Viana;Bernhard Steiner

  • Proteome analysis of Legionella vacuoles purified by magnetic immunoseparation reveals secretory and endosomal GTPases.

    Simon Urwyler;Yves Nyfeler;Curdin Ragaz;Hookeun Lee;Hookeun Lee

  • The Legionella pneumophila response regulator LqsR promotes host cell interactions as an element of the virulence regulatory network controlled by RpoS and LetA.

    André Tiaden;Thomas Spirig;Stefan S. Weber;Holger Brüggemann

  • Icm/Dot-dependent upregulation of phagocytosis by Legionella pneumophila

    Hubert Hilbi;Gil Segal;Howard A. Shuman

  • The interleukin 1beta-converting enzyme, caspase 1, is activated during Shigella flexneri-induced apoptosis in human monocyte-derived macrophages.

    Hubert Hilbi;Yajing Chen;Kavitha Thirumalai;Arturo Zychlinsky

  • Formation of a pathogen vacuole according to Legionella pneumophila: how to kill one bird with many stones

    Ivo Finsel;Hubert Hilbi;Hubert Hilbi

  • The Legionella Effector RidL Inhibits Retrograde Trafficking to Promote Intracellular Replication

    Ivo Finsel;Curdin Ragaz;Christine Hoffmann;Christopher F. Harrison

  • Planktonic Replication Is Essential for Biofilm Formation by Legionella pneumophila in a Complex Medium under Static and Dynamic Flow Conditions

    Jörg Mampel;Thomas Spirig;Stefan S. Weber;Janus A. J. Haagensen

  • The inositol polyphosphate 5-phosphatase OCRL1 restricts intracellular growth of Legionella, localizes to the replicative vacuole and binds to the bacterial effector LpnE.

    Stefan S. Weber;Curdin Ragaz;Hubert Hilbi

  • Pathogen trafficking pathways and host phosphoinositide metabolism.

    Stefan S. Weber;Curdin Ragaz;Hubert Hilbi

  • Macroautophagy is dispensable for intracellular replication of Legionella pneumophila in Dictyostelium discoideum.

    Grant P. Otto;Mary Y. Wu;Margaret Clarke;Hao Lu

  • A novel role for neutrophils as critical activators of NK cells

    Roman Spörri;Nicole Joller;Hubert Hilbi;Annette Oxenius

Frequent Co-Authors

Carmen Buchrieser
Carmen Buchrieser Institut Pasteur
Thierry Soldati
Thierry Soldati University of Geneva
Peter Dimroth
Peter Dimroth ETH Zurich
Pierre Cosson
Pierre Cosson University of Geneva
Leonardo Scapozza
Leonardo Scapozza University of Geneva
Michael Berg
Michael Berg Swiss Federal Institute of Aquatic Science and Technology
Howard A. Shuman
Howard A. Shuman University of Chicago
Søren Molin
Søren Molin Technical University of Denmark

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