World's Best Scientists 2026 revealed!

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Microbiology

D-Index
103
Citations
33035
World Ranking
357
National Ranking
42

Overview

Gad Frankel is affiliated with Imperial College London in the United Kingdom, focusing primarily on research within biochemistry, genetics, and molecular biology. Their body of work encompasses a wide range of studies, demonstrated by more than 110 publications in these fields.

The scientist has contributed extensively to several subfields, including molecular biology, endocrinology, immunology, molecular medicine, and genetics. These areas reflect a multidisciplinary approach to understanding biological systems and mechanisms.

Frankel's research topics cover critical aspects of microbiology and bacterial interactions. Notable topics include:

  • Antibiotic resistance in bacteria
  • Escherichia coli research studies
  • Bacterial genetics and biotechnology
  • Bacteriophages and microbial interactions
  • Vibrio bacteria research studies
  • Gut microbiota and health
  • Viral gastroenteritis research and epidemiology

The scientist's most recent publications highlight a focus on bacterial virulence and intestinal biology, with papers appearing in high-profile journals. Selected recent works include:

  • "Trained ILC3 responses promote intestinal defense" (2022, Science)
  • "Type III secretion system effectors form robust and flexible intracellular virulence networks" (2021, Science)
  • "Mating pair stabilization mediates bacterial conjugation species specificity" (2022, Nature Microbiology)
  • "The type III secretion system effector network hypothesis" (2021, Trends in Microbiology)
  • "Endothelial sensing of AHR ligands regulates intestinal homeostasis" (2023, Nature)

Frankel frequently publishes in venues such as bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, Gut Microbes, Proceedings of the National Academy of Sciences, and Cellular Microbiology. The highest number of publications have appeared in bioRxiv, with 20 contributions.

Collaborations form an important part of Frankel's scientific output. Frequent coauthors include Joshua L. C. Wong, Julia Sanchez-Garrido, Konstantinos Beis, Wen Wen Low, and Chloe Seddon, with collaboration counts ranging from 11 to 26 joint publications.

Best Publications

  • Fresh fruit and vegetables as vehicles for the transmission of human pathogens

    Cedric N. Berger;Samir V. Sodha;Robert K. Shaw;Patricia M. Griffin

  • Enteropathogenic and enterohaemorrhagic Escherichia coli : more subversive elements

    Gad Frankel;Alan D. Phillips;Ilan Rosenshine;Gordon Dougan

  • NLRP6 Inflammasome Orchestrates the Colonic Host-Microbial Interface by Regulating Goblet Cell Mucus Secretion

    Marta Wlodarska;Christoph A. Thaiss;Roni Nowarski;Jorge Henao-Mejia

  • A novel EspA-associated surface organelle of enteropathogenic Escherichia coli involved in protein translocation into epithelial cells

    Stuart Knutton;Ilan Rosenshine;Mark J. Pallen;Israel Nisan

  • Citrobacter rodentium of mice and man

    Rosanna Mundy;Thomas T. MacDonald;Gordon Dougan;Gad Frankel

  • Citrobacter rodentium: infection, inflammation and the microbiota

    James W. Collins;Kristie M. Keeney;Valerie F. Crepin;Vijay A. K. Rathinam

  • Enteropathogenic and enterohemorrhagic Escherichia coli infections: translocation, translocation, translocation.

    Junkal Garmendia;Gad Frankel;Valérie F. Crepin

  • An extensive repertoire of type III secretion effectors in Escherichia coli O157 and the role of lambdoid phages in their dissemination

    Toru Tobe;Scott A. Beatson;Scott A. Beatson;Hisaaki Taniguchi;Hiroyuki Abe

  • Enteropathogenic Escherichia coli: unravelling pathogenesis

    Huiwen Deborah Chen;Gad Frankel

  • Infection strategies of enteric pathogenic Escherichia coli

    Abigail Clements;Joanna C. Young;Nicholas Constantinou;Gad Frankel

  • Detection of Intimins α, β, γ, and δ, Four Intimin Derivatives Expressed by Attaching and Effacing Microbial Pathogens

    Jeannette Adu-Bobie;Gad Frankel;Christopher Bain;Azizedite Guedes Goncalves

  • Enteropathogenic and enterohaemorrhagic Escherichia coli: even more subversive elements.

    Alexander R. C. Wong;Jaclyn S. Pearson;Michael D. Bright;Diana Munera

  • Complete Genome Sequence and Comparative Genome Analysis of Enteropathogenic Escherichia coli O127:H6 Strain E2348/69

    Atsushi Iguchi;Nicholas R. Thomson;Yoshitoshi Ogura;David L Saunders

  • TccP is an enterohaemorrhagic Escherichia coli O157:H7 type III effector protein that couples Tir to the actin-cytoskeleton.

    Junkal Garmendia;Alan D. Phillips;Marie-France Carlier;Yuwen Chong

  • Citrobacter rodentium Infection in Mice Elicits a Mucosal Th1 Cytokine Response and Lesions Similar to Those in Murine Inflammatory Bowel Disease

    Lisa M. Higgins;Gad Frankel;Gill Douce;Gordon Dougan

  • A type III effector antagonizes death receptor signalling during bacterial gut infection

    Jaclyn S Pearson;Cristina Giogha;Sze Ying Ong;Catherine Lydia Kennedy

  • Enteropathogenic Escherichia coli (EPEC) adhesion to intestinal epithelial cells: role of bundle-forming pili (BFP), EspA filaments and intimin.

    Jennifer Cleary;Li-Ching Lai;Robert K. Shaw;Anna Straatman-Iwanowska

  • Binding of intimin from enteropathogenic Escherichia coli to Tir and to host cells.

    Elizabeth L. Hartland;Miranda Batchelor;Robin M. Delahay;Christine Hale

  • Organ specificity, colonization and clearance dynamics in vivo following oral challenges with the murine pathogen Citrobacter rodentium.

    Siouxsie Wiles;Simon Clare;James Harker;Alan Huett

  • Enterohaemorrhagic Escherichia coli O157:H7 target Peyer's patches in humans and cause attaching/effacing lesions in both human and bovine intestine.

    A D Phillips;S Navabpour;S Hicks;G Dougan

Frequent Co-Authors

Gordon Dougan
Gordon Dougan University of Cambridge
Elizabeth L. Hartland
Elizabeth L. Hartland Hudson Institute of Medical Research
Stuart Knutton
Stuart Knutton University of Birmingham
Alan D. Phillips
Alan D. Phillips University College London
Mark J. Pallen
Mark J. Pallen University of East Anglia
Mark P. Stevens
Mark P. Stevens University of Edinburgh
Claire Jenkins
Claire Jenkins Public Health England
Stephen Matthews
Stephen Matthews Imperial College London
Thomas T. MacDonald
Thomas T. MacDonald University of Southampton
Cameron P. Simmons
Cameron P. Simmons University College London

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