D-Index & Metrics Best Publications
Immunology
UK
2023

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Immunology D-index 101 Citations 31,811 386 World Ranking 409 National Ranking 37
Medicine D-index 102 Citations 32,821 438 World Ranking 4572 National Ranking 447

Research.com Recognitions

Awards & Achievements

2023 - Research.com Immunology in United Kingdom Leader Award

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Immune system
  • Internal medicine

Thomas T. MacDonald mainly investigates Immunology, Inflammatory bowel disease, Cytokine, Tumor necrosis factor alpha and Immune system. As part of his studies on Immunology, Thomas T. MacDonald frequently links adjacent subjects like Lamina propria. His Inflammatory bowel disease research incorporates elements of Interferon, Colitis and Ulcerative colitis.

His biological study spans a wide range of topics, including T cell, Interleukin 21 and Hyperplasia. Thomas T. MacDonald combines subjects such as Cancer research and Matrix metalloproteinase, Metalloproteinase with his study of Tumor necrosis factor alpha. His Immune system research is multidisciplinary, relying on both Signal transduction and Microbiology.

His most cited work include:

  • Immunity, Inflammation, and Allergy in the Gut (827 citations)
  • Tumour necrosis factor alpha in stool as a marker of intestinal inflammation (608 citations)
  • Tumor necrosis factor α-producing cells in the intestinal mucosa of children with inflammatory bowel disease (508 citations)

What are the main themes of his work throughout his whole career to date?

Thomas T. MacDonald mainly focuses on Immunology, Inflammatory bowel disease, Cytokine, Immune system and Lamina propria. Thomas T. MacDonald has included themes like Crohn's disease and Disease in his Immunology study. His studies deal with areas such as Proinflammatory cytokine, Cancer research, Colitis and Ulcerative colitis as well as Inflammatory bowel disease.

His study explores the link between Cytokine and topics such as Interleukin 21 that cross with problems in IL-2 receptor. His Immune system study combines topics from a wide range of disciplines, such as Antigen and Microbiology. His studies examine the connections between Lamina propria and genetics, as well as such issues in T cell, with regards to Molecular biology.

He most often published in these fields:

  • Immunology (56.21%)
  • Inflammatory bowel disease (24.83%)
  • Cytokine (21.67%)

What were the highlights of his more recent work (between 2012-2021)?

  • Immunology (56.21%)
  • Inflammatory bowel disease (24.83%)
  • Cytokine (21.67%)

In recent papers he was focusing on the following fields of study:

His primary areas of investigation include Immunology, Inflammatory bowel disease, Cytokine, Ulcerative colitis and Internal medicine. His study looks at the relationship between Immunology and fields such as Ex vivo, as well as how they intersect with chemical problems. The Inflammatory bowel disease study combines topics in areas such as Tumor necrosis factor alpha, Colitis, STAT1, Neutrophil elastase and Crohn's disease.

His study on Cytokine also encompasses disciplines like

  • Intestinal mucosa that connect with fields like Interleukin 21 and Molecular biology,
  • Cancer research that intertwine with fields like Cell growth and Cytotoxic T cell. His Ulcerative colitis research includes elements of Lamina propria, Elastase, Human neutrophil, Elafin and Kinase. His Internal medicine research focuses on subjects like Gastroenterology, which are linked to Barrier function.

Between 2012 and 2021, his most popular works were:

  • Human Intestinal Barrier Function in Health and Disease. (284 citations)
  • Th17-type cytokines, IL-6 and TNF-α synergistically activate STAT3 and NF-kB to promote colorectal cancer cell growth. (228 citations)
  • Homeostasis of the Gut Barrier and Potential Biomarkers. (162 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Immune system
  • Internal medicine

The scientist’s investigation covers issues in Immunology, Immune system, Inflammatory bowel disease, Tumor necrosis factor alpha and Ulcerative colitis. His study in Cytokine, Inflammation, Interleukin 17, Interleukin and Proinflammatory cytokine is carried out as part of his Immunology studies. As a member of one scientific family, Thomas T. MacDonald mostly works in the field of Cytokine, focusing on Intestinal mucosa and, on occasion, Interleukin 21 and Flow cytometry.

His Inflammatory bowel disease study integrates concerns from other disciplines, such as Irritable bowel syndrome, Adalimumab, Lamina propria, Autoantibody and Barrier function. He interconnects Biopsy, Transcription factor and Pathogenesis in the investigation of issues within Tumor necrosis factor alpha. Thomas T. MacDonald focuses mostly in the field of Ulcerative colitis, narrowing it down to topics relating to Crohn's disease and, in certain cases, Pulmonary fibrosis.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Immunity, Inflammation, and Allergy in the Gut

Thomas T. MacDonald;Giovanni Monteleone.
Science (2005)

1274 Citations

Tumour necrosis factor alpha in stool as a marker of intestinal inflammation

C.P. Braegger;S. Nicholls;S.H. Murch;T.T. MacDonald.
The Lancet (1992)

869 Citations

Tumor necrosis factor α-producing cells in the intestinal mucosa of children with inflammatory bowel disease

Emma J. Breese;Colin A. Michie;Stuart W. Nicholls;Simon H. Murch.
Gastroenterology (1994)

724 Citations

Blocking Smad7 restores TGF-β1 signaling in chronic inflammatory bowel disease

Giovanni Monteleone;Andrea Kumberova;Nicholas M. Croft;Catriona McKenzie.
Journal of Clinical Investigation (2001)

707 Citations

Location of tumour necrosis factor alpha by immunohistochemistry in chronic inflammatory bowel disease.

S H Murch;C P Braegger;J A Walker-Smith;T T MacDonald.
Gut (1993)

644 Citations

Tumour necrosis factor-alpha and interferon-gamma production measured at the single cell level in normal and inflamed human intestine.

T T MacDonald;P Hutchings;M Y Choy;S Murch.
Clinical and Experimental Immunology (2008)

594 Citations

Serum concentrations of tumour necrosis factor alpha in childhood chronic inflammatory bowel disease.

S H Murch;V A Lamkin;M O Savage;J A Walker-Smith.
Gut (1991)

587 Citations

Human Intestinal Barrier Function in Health and Disease.

Julia König;Jerry Wells;Patrice D. Cani;Clara L. García-Ródenas.
Clinical and translational gastroenterology (2016)

561 Citations

Curcumin as a therapeutic agent: the evidence from in vitro, animal and human studies

Jenny Epstein;Ian R. Sanderson;Thomas T. MacDonald.
British Journal of Nutrition (2010)

545 Citations

Citrobacter rodentium of mice and man

Rosanna Mundy;Thomas T. MacDonald;Gordon Dougan;Gad Frankel.
Cellular Microbiology (2005)

534 Citations

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