World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
113
Citations
40571
World Ranking
439
National Ranking
39

Medicine

D-Index
113
Citations
40739
World Ranking
5009
National Ranking
492

Thomas T. MacDonald publication distribution in Immunology in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Immunology in 2026. The highlighted bar marks where Thomas T. MacDonald sits on this spectrum.

62–71 publications: 9 scientists 72–81 publications: 23 scientists 82–91 publications: 40 scientists 92–101 publications: 72 scientists 102–111 publications: 86 scientists 112–121 publications: 108 scientists 122–131 publications: 150 scientists 132–141 publications: 160 scientists 142–151 publications: 159 scientists 152–161 publications: 189 scientists 162–171 publications: 166 scientists 172–181 publications: 181 scientists 182–191 publications: 188 scientists 192–201 publications: 187 scientists 202–211 publications: 178 scientists 212–221 publications: 158 scientists 222–231 publications: 168 scientists 232–241 publications: 159 scientists 242–251 publications: 160 scientists 252–261 publications: 148 scientists 262–271 publications: 116 scientists 272–281 publications: 125 scientists 282–291 publications: 115 scientists 292–301 publications: 111 scientists 302–311 publications: 95 scientists 312–321 publications: 97 scientists 322–331 publications: 97 scientists 332–341 publications: 99 scientists 342–351 publications: 96 scientists 352–361 publications: 68 scientists 362–371 publications: 76 scientists 372–381 publications: 71 scientists 382–391 publications: 71 scientists 392–401 publications: 62 scientists 402–411 publications: 54 scientists 412–421 publications: 41 scientists 422–431 publications: 63 scientists 432–441 publications: 53 scientists 442–451 publications: 31 scientists 452–461 publications: 42 scientists 462–471 publications: 40 scientists 472–481 publications: 29 scientists 482–491 publications: 34 scientists 492–501 publications: 30 scientists 502–511 publications: 23 scientists 512–521 publications: 41 scientists 522–531 publications: 29 scientists 532–541 publications: 28 scientists 542–551 publications: 16 scientists 552–561 publications: 18 scientists 562–571 publications: 18 scientists 572–581 publications: 17 scientists 582–591 publications: 17 scientists 592–601 publications: 17 scientists 602–611 publications: 19 scientists 612–621 publications: 13 scientists 622–631 publications: 12 scientists 632–641 publications: 11 scientists 642–651 publications: 16 scientists 652–661 publications: 9 scientists 662–671 publications: 5 scientists 672–681 publications: 13 scientists 682–691 publications: 12 scientists 692–701 publications: 6 scientists 702–711 publications: 6 scientists 712–721 publications: 9 scientists 722–731 publications: 9 scientists 732–741 publications: 6 scientists 742–751 publications: 11 scientists 752–761 publications: 10 scientists 762–771 publications: 7 scientists 772–781 publications: 12 scientists 782–791 publications: 7 scientists 792–801 publications: 5 scientists 802–806 publications: 1 scientists 807+ publications: 100 scientists
62 publications 807+

This scientist: 514 publications — 90th percentile

90% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 807 publications or more.

Thomas T. MacDonald D-index placement in Immunology in 2026

The chart shows the D-index (discipline H-index) distribution of Immunology scientists ranked by Research.com in 2026. The highlighted bar marks where Thomas T. MacDonald sits on this spectrum.

40–41 D-Index: 28 scientists 42–43 D-Index: 91 scientists 44–45 D-Index: 157 scientists 46–47 D-Index: 192 scientists 48–49 D-Index: 175 scientists 50–51 D-Index: 188 scientists 52–53 D-Index: 177 scientists 54–55 D-Index: 155 scientists 56–57 D-Index: 194 scientists 58–59 D-Index: 201 scientists 60–61 D-Index: 197 scientists 62–63 D-Index: 201 scientists 64–65 D-Index: 173 scientists 66–67 D-Index: 167 scientists 68–69 D-Index: 172 scientists 70–71 D-Index: 199 scientists 72–73 D-Index: 184 scientists 74–75 D-Index: 133 scientists 76–77 D-Index: 162 scientists 78–79 D-Index: 127 scientists 80–81 D-Index: 121 scientists 82–83 D-Index: 125 scientists 84–85 D-Index: 121 scientists 86–87 D-Index: 102 scientists 88–89 D-Index: 96 scientists 90–91 D-Index: 75 scientists 92–93 D-Index: 72 scientists 94–95 D-Index: 74 scientists 96–97 D-Index: 66 scientists 98–99 D-Index: 68 scientists 100–101 D-Index: 49 scientists 102–103 D-Index: 60 scientists 104–105 D-Index: 54 scientists 106–107 D-Index: 36 scientists 108–109 D-Index: 23 scientists 110–111 D-Index: 52 scientists 112–113 D-Index: 41 scientists 114–115 D-Index: 34 scientists 116–117 D-Index: 25 scientists 118–119 D-Index: 28 scientists 120–121 D-Index: 11 scientists 122–123 D-Index: 20 scientists 124–125 D-Index: 27 scientists 126–127 D-Index: 19 scientists 128–129 D-Index: 20 scientists 130–131 D-Index: 16 scientists 132–133 D-Index: 17 scientists 134–135 D-Index: 14 scientists 136–137 D-Index: 15 scientists 138–139 D-Index: 9 scientists 140–141 D-Index: 11 scientists 142–143 D-Index: 9 scientists 144–145 D-Index: 9 scientists 146–147 D-Index: 7 scientists 148–149 D-Index: 7 scientists 150–151 D-Index: 7 scientists 152–153 D-Index: 5 scientists 154–155 D-Index: 8 scientists 156 D-Index: 6 scientists 157+ D-Index: 96 scientists
40 D-Index 157+

This scientist: 113 D-Index — 91st percentile

91% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 157 D-Index or more.

Overview

Thomas T. MacDonald is a researcher affiliated with Queen Mary University of London in the United Kingdom. Their work spans several interconnected fields, mainly focusing on medicine, biochemistry, genetics, molecular biology, immunology, and microbiology.

Their research contributions are concentrated particularly within the study of inflammatory bowel disease and related immunological and molecular mechanisms. Key topics in their work include:

  • Inflammatory Bowel Disease
  • Galectins and Cancer Biology
  • Protein Degradation and Inhibitors
  • Ubiquitin and Proteasome Pathways
  • Multiple Myeloma Research and Treatments
  • Psoriasis: Treatment and Pathogenesis
  • Whipple's Disease and Interleukins

MacDonald has published research in a variety of journals, reflecting a diverse range of biological and clinical topics. Frequent publication venues include:

  • Communications Biology
  • Nature Communications
  • Journal of Inflammation Research
  • Scientific Reports
  • APOPTOSIS

They have collaborated repeatedly with several coauthors, indicating ongoing partnerships in their scientific work. Frequent coauthors include:

  • Anna Vossenkämper
  • Antonio Di Sabatino
  • Pamela A. Haile
  • Bartholomew J. Votta
  • Allison M. Beal

Selected research papers illustrate the scope and scale of their contributions:

  • "Extended pharmacodynamic responses observed upon PROTAC-mediated degradation of RIPK2," 2020, Communications Biology
  • "Interleukin-22 regulates neutrophil recruitment in ulcerative colitis and is associated with resistance to ustekinumab therapy," 2022, Nature Communications
  • "Human Neutrophil Elastase Proteolytic Activity in Ulcerative Colitis Favors the Loss of Function of Therapeutic Monoclonal Antibodies," 2020, Journal of Inflammation Research
  • "Preclinical development of a bispecific TNFα/IL-23 neutralising domain antibody as a novel oral treatment for inflammatory bowel disease," 2021, Scientific Reports
  • "BindingDB Entry 50008194: Discovery of a First-in-Class Receptor Interacting Protein 2 (RIP2) Kinase Specific Clinical Candidate, 2-((4-(Benzo[," 2021, PubMed

Their work primarily addresses mechanisms underlying inflammatory and immune-mediated diseases using molecular biology techniques. This includes examining cytokine pathways, protein degradation mechanisms, and therapeutic antibody resistance relevant to clinical conditions such as ulcerative colitis and multiple myeloma.

Best Publications

  • Immunity, Inflammation, and Allergy in the Gut

    Thomas T. MacDonald;Giovanni Monteleone

  • Tumour necrosis factor alpha in stool as a marker of intestinal inflammation

    C.P. Braegger;S. Nicholls;S.H. Murch;T.T. MacDonald

  • Human Intestinal Barrier Function in Health and Disease.

    Julia König;Jerry Wells;Patrice D. Cani;Clara L. García-Ródenas

  • Blocking Smad7 restores TGF-β1 signaling in chronic inflammatory bowel disease

    Giovanni Monteleone;Andrea Kumberova;Nicholas M. Croft;Catriona McKenzie

  • Tumor necrosis factor α-producing cells in the intestinal mucosa of children with inflammatory bowel disease

    Emma J. Breese;Colin A. Michie;Stuart W. Nicholls;Simon H. Murch

  • Aryl Hydrocarbon Receptor-Induced Signals Up-regulate IL-22 Production and Inhibit Inflammation in the Gastrointestinal Tract

    Ivan Monteleone;Angelamaria Rizzo;Massimiliano Sarra;Giuseppe Sica

  • Location of tumour necrosis factor alpha by immunohistochemistry in chronic inflammatory bowel disease.

    S H Murch;C P Braegger;J A Walker-Smith;T T MacDonald

  • Th17-type cytokines, IL-6 and TNF-α synergistically activate STAT3 and NF-kB to promote colorectal cancer cell growth.

    V De Simone;E Franzè;G Ronchetti;A Colantoni

  • Homeostasis of the Gut Barrier and Potential Biomarkers.

    Jerry M. Wells;Robert J. Brummer;Muriel Derrien;Thomas T. MacDonald

  • Curcumin as a therapeutic agent: the evidence from in vitro, animal and human studies

    Jenny Epstein;Ian R. Sanderson;Thomas T. MacDonald

  • Tumour necrosis factor-alpha and interferon-gamma production measured at the single cell level in normal and inflamed human intestine.

    T T MacDonald;P Hutchings;M Y Choy;S Murch

  • Serum concentrations of tumour necrosis factor alpha in childhood chronic inflammatory bowel disease.

    S H Murch;V A Lamkin;M O Savage;J A Walker-Smith

  • Citrobacter rodentium of mice and man

    Rosanna Mundy;Thomas T. MacDonald;Gordon Dougan;Gad Frankel

  • Inflammatory processes have differential effects on claudins 2, 3 and 4 in colonic epithelial cells

    Shyam Prasad;Roberto Mingrino;Katri Kaukinen;Katherine L Hayes

  • Mucosal healing and a fall in mucosal pro-inflammatory cytokine mRNA induced by a specific oral polymeric diet in paediatric Crohn's disease.

    J. M. E. Fell;M. Paintin;F. Arnaud-Battandier;R. M. Beattie

  • Can probiotics modulate human disease by impacting intestinal barrier function

    Peter A. Bron;Michiel Kleerebezem;Robert Jan Brummer;Patrice D. Cani

  • Characterisation of acute murine dextran sodium sulphate colitis: cytokine profile and dose dependency

    Bernhard Egger;Mona Bajaj-Elliott;Thomas T. MacDonald;Roman Inglin

  • Evidence that activated mucosal T cells play a role in the pathogenesis of enteropathy in human small intestine.

    T T MacDonald;J Spencer

  • Discovery of a First-in-Class Receptor Interacting Protein 1 (RIP1) Kinase Specific Clinical Candidate (GSK2982772) for the Treatment of Inflammatory Diseases

    Philip A. Harris;Scott B. Berger;Jae U. Jeong;Rakesh Nagilla

  • Interleukin-2- and interferon-gamma-secreting T cells in normal and diseased human intestinal mucosa.

    E Breese;C P Braegger;C J Corrigan;J A Walker-Smith

  • S1731 Differential Regulation of Interleukin-17 and Interferon-γ Production in Inflammatory Bowel Disease

    L. Rovedatti;T. Kudo;P. Biancheri;M. Sarra

Frequent Co-Authors

Giovanni Monteleone
Giovanni Monteleone University of Rome Tor Vergata
Francesco Pallone
Francesco Pallone University of Rome Tor Vergata
Gino Roberto Corazza
Gino Roberto Corazza University of Pavia
Massimo Fantini
Massimo Fantini Precision Biologics
Graham M. Lord
Graham M. Lord University of Manchester
Jo Spencer
Jo Spencer King's College London
Gad Frankel
Gad Frankel Imperial College London
Markus F. Neurath
Markus F. Neurath University of Erlangen-Nuremberg
Gordon Dougan
Gordon Dougan University of Cambridge
Giovanna Lombardi
Giovanna Lombardi King's College London

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