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Immunology

D-Index
66
Citations
18341
World Ranking
2735
National Ranking
241

Overview

Jo Spencer is affiliated with King's College London in the United Kingdom. Their research primarily centers on the fields of Immunology and Microbiology, Medicine, and Biochemistry, Genetics, and Molecular Biology. Throughout their career, they have contributed extensively to subfields such as Immunology, Molecular Biology, Oncology, Infectious Diseases, and Surgery.

The main topics covered in their work include:

  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • Cancer Immunotherapy and Biomarkers
  • Immunotherapy and Immune Responses
  • Single-cell and spatial transcriptomics
  • Colorectal Cancer Treatments and Studies
  • SARS-CoV-2 and COVID-19 Research

Jo Spencer has published research in several venues, with notable frequent publications in:

  • Zenodo (CERN European Organization for Nuclear Research)
  • bioRxiv (Cold Spring Harbor Laboratory)
  • The Journal of Experimental Medicine
  • Nature Communications
  • Clinical & Experimental Immunology

Some of their recent papers include:

  • Human gut-associated lymphoid tissues (GALT); diversity, structure, and function (2021), published in Mucosal Immunology
  • Immunogenomics of Colorectal Cancer Response to Checkpoint Blockade: Analysis of the KEYNOTE 177 Trial and Validation Cohorts (2021), Gastroenterology
  • Asplenia and spleen hypofunction (2022), Nature Reviews Disease Primers
  • Human marginal zone B cell development from early T2 progenitors (2020), The Journal of Experimental Medicine
  • Gut-associated lymphoid tissue: a microbiota-driven hub of B cell immunity (2024), Trends in Immunology

Frequent co-authors who have collaborated with Jo Spencer include:

  • Lucia Montorsi
  • Francesca D. Ciccarelli
  • Michael J. Pitcher
  • Michele Bortolomeazzi
  • Manuel Rodríguez-Justo

Best Publications

  • Immunoproliferative small-intestinal disease. An immunohistochemical study.

    Peter G. Isaacson;Ahmet Dogan;Stephen K. Price;Jo Spencer

  • The response of cells from low-grade B-cell gastric lymphomas of mucosa-associated lymphoid tissue to Helicobacter pylori

    T Hussell;P G Isaacson;J E Crabtree;J Spencer

  • Malignant lymphoma of mucosa‐associated lymphoid tissue

    P. G. Isaacson;J. Spencer

  • Ectopic Lymphoid Structures Support Ongoing Production of Class-Switched Autoantibodies in Rheumatoid Synovium

    Frances Humby;Michele Bombardieri;Antonio Manzo;Stephen Kelly

  • HELICOBACTER PYLORI‐SPECIFIC TUMOUR‐INFILTRATING T CELLS PROVIDE CONTACT DEPENDENT HELP FOR THE GROWTH OF MALIGNANT B CELLS IN LOW‐GRADE GASTRIC LYMPHOMA OF MUCOSA‐ASSOCIATED LYMPHOID TISSUE

    Tracey Hussell;Peter G. Isaacson;Jean E. Crabtree;Jo Spencer

  • Evidence that activated mucosal T cells play a role in the pathogenesis of enteropathy in human small intestine.

    T T MacDonald;J Spencer

  • MALIGNANT HISTIOCYTOSIS OF THE INTESTINE: A T-CELL LYMPHOMA

    P.G. Isaacson;Jo Spencer;C.E. Connolly;D.J. Pollock

  • Analysis of mutations in immunoglobulin heavy chain variable region genes of microdissected marginal zone (MGZ) B cells suggests that the MGZ of human spleen is a reservoir of memory B cells.

    D K Dunn-Walters;P G Isaacson;J Spencer

  • Human gut-associated lymphoid tissues (GALT); diversity, structure, and function.

    Urs M Mörbe;Peter B Jørgensen;Thomas M Fenton;Nicole von Burg

  • Expression of disulfide-linked and non-disulfide-linked forms of the T cell receptor γ/δ heterodimer in human intestinal intraepithelial lymphocytes

    Jo Spencer;Peter G. Isaacson;Tim C. Diss;Thomas T. Macdonald

  • Expression of lymphocyte-endothelial receptor-ligand pairs, α4β7/MAdCAM-1 and OX40/OX40 ligand in the colon and jejunum of patients with inflammatory bowel disease

    H S Souza;C C S Elia;J Spencer;T T MacDonald

  • CXCL13, CCL21, and CXCL12 expression in salivary glands of patients with Sjögren's syndrome and MALT lymphoma: Association with reactive and malignant areas of lymphoid organization

    Francesca Barone;Michele Bombardieri;Manuela Maria Rosado;Peter Roger Morgan

  • The human gut contains a novel population of B lymphocytes which resemble marginal zone cells.

    J Spencer;T Finn;K A Pulford;D Y Mason

  • Primary B-cell gastric lymphoma

    Peter G. Isaacson;Jo Spencer;Teresa Finn

  • Mouse and human intestinal immunity: same ballpark, different players; different rules, same score

    D L Gibbons;D L Gibbons;J Spencer

  • Activation-Induced Cytidine Deaminase Expression in Follicular Dendritic Cell Networks and Interfollicular Large B Cells Supports Functionality of Ectopic Lymphoid Neogenesis in Autoimmune Sialoadenitis and MALT Lymphoma in Sjögren’s Syndrome

    Michele Bombardieri;Francesca Barone;Frances Humby;Stephen Kelly

  • Changes in intraepithelial lymphocyte subpopulations in coeliac disease and enteropathy associated T cell lymphoma (malignant histiocytosis of the intestine).

    J Spencer;T T MacDonald;T C Diss;J A Walker-Smith

  • The development of gut associated lymphoid tissue in the terminal ileum of fetal human intestine.

    J Spencer;T T MacDonald;T Finn;P G Isaacson

  • Human Peyer's patches: an immunohistochemical study.

    J. O. Spencer;T. Finn;P. G. Isaacson

  • Gamma/delta T cells and the diagnosis of coeliac disease

    J Spencer;P G Isaacson;T T MacDonald;A J Thomas

  • Human marginal-zone B cells

    Jo Spencer;Marta E Perry;Deborah K Dunn-Walters

Frequent Co-Authors

Deborah K. Dunn-Walters
Deborah K. Dunn-Walters University of Surrey
Peter G. Isaacson
Peter G. Isaacson University College London
Jeremy D. Sanderson
Jeremy D. Sanderson Guy's and St Thomas' NHS Foundation Trust
Thomas T. MacDonald
Thomas T. MacDonald University of Southampton
Stephen Challacombe
Stephen Challacombe King's College London
Mervyn Singer
Mervyn Singer University College London
Tracy Hussell
Tracy Hussell University of Manchester
Ahmet Dogan
Ahmet Dogan Memorial Sloan Kettering Cancer Center
Michele Bombardieri
Michele Bombardieri Queen Mary University of London
Costantino Pitzalis
Costantino Pitzalis Queen Mary University of London

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