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Deborah K. Dunn-Walters

Deborah K. Dunn-Walters

D-Index & Metrics

Immunology

D-Index
47
Citations
7561
World Ranking
4541
National Ranking
392

Overview

Deborah K. Dunn-Walters is affiliated with the University of Surrey in the United Kingdom, with a research focus primarily situated within the fields of Medicine, Immunology and Microbiology, and Biochemistry, Genetics and Molecular Biology.

Their work spans multiple subfields, notably Immunology, Molecular Biology, Infectious Diseases, Radiology, Nuclear Medicine and Imaging, and Dermatology. Key topics covered include T-cell and B-cell Immunology, COVID-19 Clinical Research Studies, Immune Cell Function and Interaction, Metabolomics and Mass Spectrometry Studies, Monoclonal and Polyclonal Antibodies Research, Single-cell and spatial transcriptomics, and Dermatological and COVID-19 studies.

Frequent publication venues for their work include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Zenodo (CERN European Organization for Nuclear Research)
  • Frontiers in Immunology
  • Scientific Reports
  • Cancer Research

Collaborations have regularly involved coauthors such as Joseph Ng, Franca Fraternali, Alexander Stewart, Katie Longman, and Cécile Frampas, indicating a network of partnerships with multiple researchers across related scientific areas.

Significant recent publications illustrate the breadth of their research interests and contributions. These include:

  • "Thioredoxin is a metabolic rheostat controlling regulatory B cells," 2024, Nature Immunology
  • "Single-Cell Transcriptomic Analyses Define Distinct Peripheral B Cell Subsets and Discrete Development Pathways," 2021, Frontiers in Immunology
  • "Tumor-Infiltrating B Lymphocyte Profiling Identifies IgG-Biased, Clonally Expanded Prognostic Phenotypes in Triple-Negative Breast Cancer," 2021, Cancer Research
  • "Inflammation-induced IgE promotes epithelial hyperplasia and tumour growth," 2020, eLife
  • "Vitamin D status, body mass index, ethnicity and COVID-19: Initial analysis of the first-reported UK Biobank COVID-19 positive cases (n 580) compared with negative controls (n 723)," 2020, bioRxiv (Cold Spring Harbor Laboratory)

The scientist's research reflects an engagement with immune cell profiling, infectious disease impact, cancer immunology, and metabolic regulation in immune contexts.

Best Publications

  • B-cell diversity decreases in old age and is correlated with poor health status

    Kate L. Gibson;Yu-Chang Wu;Yvonne Barnett;Orla Duggan

  • Analysis of mutations in immunoglobulin heavy chain variable region genes of microdissected marginal zone (MGZ) B cells suggests that the MGZ of human spleen is a reservoir of memory B cells.

    D K Dunn-Walters;P G Isaacson;J Spencer

  • High-throughput immunoglobulin repertoire analysis distinguishes between human IgM memory and switched memory B-cell populations

    Unknown

  • Redemption of autoantibodies on anergic B cells by variable-region glycosylation and mutation away from self-reactivity

    Zahra Sabouri;Peter Schofield;Keisuke Horikawa;Emily Spierings

  • B cells and aging: molecules and mechanisms

    Michael P. Cancro;Yi Hao;Jean L. Scholz;Richard L. Riley

  • The relationship between CD27 negative and positive B cell populations in human peripheral blood.

    Yu-Chang Bryan Wu;David Kipling;Deborah Kay Dunn-Walters

  • The ageing B cell population: composition and function.

    Alexander Ademokun;Yu-Chang Wu;Deborah Dunn-Walters

  • Vaccination-induced changes in human B-cell repertoire and pneumococcal IgM and IgA antibody at different ages

    Alexander Ademokun;Yu-Chang Wu;Victoria Martin;Rajive Mitra

  • Mechanisms of immunosenescence

    Calogero Caruso;Silvio Buffa;Giuseppina Candore;Giuseppina Colonna-Romano

  • Human marginal-zone B cells

    Jo Spencer;Marta E Perry;Deborah K Dunn-Walters

  • Single-Cell Transcriptomic Analyses Define Distinct Peripheral B Cell Subsets and Discrete Development Pathways

    Alexander Stewart;Joseph Chi Fung Ng;Gillian Wallis;Vasiliki Tsioligka

  • Age-Related Changes in Human Peripheral Blood IGH Repertoire Following Vaccination.

    Yu-Chang Bryan Wu;David Glyn Kipling;Deborah K. Dunn-Walters

  • B cell repertoire and ageing.

    Deborah K Dunn-Walters;Alexander A Ademokun

  • Hypermutation, diversity and dissemination of human intestinal lamina propria plasma cells.

    Deborah K. Dunn‐Walters;Laurent Boursier;Jo Spencer

  • B cells and immunosenescence: a focus on IgG+IgD-CD27- (DN) B cells in aged humans.

    Matteo Bulati;Silvio Buffa;Giuseppina Candore;Calogero Caruso

  • B cell immunosenescence: different features of naive and memory B cells in elderly

    Silvio Buffa;Matteo Bulati;Mariavaleria Pellicanò;Deborah K. Dunn-Walters

  • Sequence analysis of human IgVH genes indicates that ileal lamina propria plasma cells are derived from Peyer's patches

    Deborah K. Dunn-Walters;Peter G. Isaacson;Jo Spencer

  • A Reassessment of IgM Memory Subsets in Humans.

    Davide Bagnara;Margherita Squillario;David Kipling;Thierry Mora

  • Epithelial damage and tissue γδ T cells promote a unique tumor-protective IgE response

    Greg Crawford;Mark David Hayes;Rocio Castro Seoane;Sophie Ward

  • Age- and tissue-specific differences in human germinal center B cell selection revealed by analysis of IgVH gene hypermutation and lineage trees.

    Monica Banerjee;Ramit Mehr;Alex Belelovsky;Jo Spencer

  • Effect of somatic hypermutation on potential N-glycosylation sites in human immunoglobulin heavy chain variable regions.

    Deborah Dunn-Walters;Laurent Boursier;Jo Spencer

  • Ageing of the B-cell repertoire

    Victoria Georgina Martin;Yu-Chang Bryan Wu;David Kipling;Deborah Kay Dunn-Walters

Frequent Co-Authors

Jo Spencer
Jo Spencer King's College London
Iris Barshack
Iris Barshack Sheba Medical Center
Peter G. Isaacson
Peter G. Isaacson University College London
Qiang Pan-Hammarström
Qiang Pan-Hammarström Karolinska Institute
Lennart Hammarström
Lennart Hammarström Karolinska Institute
PG Isaacson
PG Isaacson The Royal Free Hospital
Giuseppina Candore
Giuseppina Candore University of Palermo
Sophia N. Karagiannis
Sophia N. Karagiannis King's College London
David Voehringer
David Voehringer University of Erlangen-Nuremberg
Roshini S. Abraham
Roshini S. Abraham Nationwide Children's Hospital

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