Jacques J.M. van Dongen mainly investigates Immunology, Molecular biology, Gene rearrangement, B cell and Minimal residual disease. His is doing research in Antigen, Antibody, CD19, Immunophenotyping and Immune system, both of which are found in Immunology. His Molecular biology research incorporates themes from Dendritic cell, Recombination-activating gene, RAG2 and Gene, Severe combined immunodeficiency.
The various areas that he examines in his Gene rearrangement study include Cellular differentiation, T cell, T-cell receptor, Regulation of gene expression and Polymerase chain reaction. His B cell research is multidisciplinary, incorporating elements of DNA and Immunoglobulin heavy chain. His study in Minimal residual disease is interdisciplinary in nature, drawing from both Flow cytometry, Acute lymphocytic leukemia and Oncology.
Immunology, Molecular biology, Antibody, Internal medicine and Immunophenotyping are his primary areas of study. His work in B cell, Bone marrow, Immune system, EuroFlow and Antigen are all subfields of Immunology research. In his study, Polymerase chain reaction is inextricably linked to Gene rearrangement, which falls within the broad field of Molecular biology.
Jacques J.M. van Dongen has researched Internal medicine in several fields, including Surgery and Oncology. In Immunophenotyping, he works on issues like Leukemia, which are connected to Cancer research. The study incorporates disciplines such as Acute lymphocytic leukemia and Transplantation in addition to Minimal residual disease.
His scientific interests lie mostly in Immunophenotyping, Immunology, Flow cytometry, EuroFlow and Antibody. His research integrates issues of Cancer research, Leukemia and Bone marrow in his study of Immunophenotyping. His Flow cytometry research is multidisciplinary, relying on both Myeloid, Pathology, Lymphocyte, Tissue damage and Multiple myeloma.
His research in EuroFlow intersects with topics in Orientation, Newborn screening and Acute leukemia. Jacques J.M. van Dongen specializes in Antibody, namely B cell. His B cell research integrates issues from Second line treatment, Chronic lymphocytic leukemia, Melphalan and Minimal residual disease.
The scientist’s investigation covers issues in Internal medicine, Oncology, Minimal residual disease, EuroFlow and Flow cytometry. His Internal medicine study integrates concerns from other disciplines, such as Text mining and Fusion gene. His studies in Oncology integrate themes in fields like Survival rate, Clinical endpoint, Randomized controlled trial and Surrogate endpoint.
His Minimal residual disease research is multidisciplinary, incorporating perspectives in Progression-free survival, Chemoimmunotherapy, Primer, Computational biology and DNA sequencing. His work in Flow cytometry addresses subjects such as Cancer research, which are connected to disciplines such as Immunophenotyping. Jacques J.M. van Dongen integrates Viral pathogenesis with Immunology in his research.
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Prognostic value of minimal residual disease in acute lymphoblastic leukaemia in childhood
Jacques Jm van Dongen;Taku Seriu;E Renate Panzer-Grümayer;Andrea Biondi.
The Lancet (1998)
Immunophenotyping of blood lymphocytes in childhood: Reference values for lymphocyte subpopulations
W.Marieke Comans-Bitter;Ronald de Groot;René van den Beemd;Herman J. Neijens.
The Journal of Pediatrics (1997)
Molecular response to treatment redefines all prognostic factors in children and adolescents with B-cell precursor acute lymphoblastic leukemia: results in 3184 patients of the AIEOP-BFM ALL 2000 study
Valentino Conter;Claus R. Bartram;Maria Grazia Valsecchi;Andre Schrauder.
Blood (2010)
An antibody-deficiency syndrome due to mutations in the CD19 gene
Menno C van Zelm;Ismail Reisli;Mirjam van der Burg;Diana Castaño.
The New England Journal of Medicine (2006)
Final Report of the Efficacy and Safety of Gemtuzumab Ozogamicin (Mylotarg) in Patients With CD33-positive Acute Myeloid Leukemia in First Recurrence
Richard A. Larson;Eric L. Sievers;Eric L. Sievers;Edward A. Stadtmauer;Bob Löwenberg.
Cancer (2005)
Increased cell division but not thymic dysfunction rapidly affects the T-cell receptor excision circle content of the naive T cell population in HIV-1 infection.
Mette D. Hazenberg;Sigrid A. Otto;James W.T. Cohen Stuart;Martie C.M. Verschuren.
Nature Medicine (2000)
Targeting of the CD33-calicheamicin immunoconjugate Mylotarg (CMA-676) in acute myeloid leukemia: in vivo and in vitro saturation and internalization by leukemic and normal myeloid cells.
Vincent H. J. van der Velden;Jeroen G. te Marvelde;Patricia G. Hoogeveen;Irwin D. Bernstein.
Blood (2001)
Minimal residual disease diagnostics in acute lymphoblastic leukemia: need for sensitive, fast, and standardized technologies
Jacques J. M. van Dongen;Vincent H. J. van der Velden;Monika Brüggemann;Alberto Orfao.
Blood (2015)
T cell receptor excision circles as markers for recent thymic emigrants: basic aspects, technical approach, and guidelines for interpretation.
Mette D. Hazenberg;Martie C. M. Verschuren;Dörte Hamann;Frank Miedema.
Journal of Molecular Medicine (2001)
New insights on human T cell development by quantitative T cell receptor gene rearrangement studies and gene expression profiling
Willem A. Dik;Karin Pike-Overzet;Floor Weerkamp;Dick de Ridder;Dick de Ridder.
Journal of Experimental Medicine (2005)
Profile was last updated on December 6th, 2021.
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