H-Index & Metrics Top Publications

H-Index & Metrics

Discipline name H-index Citations Publications World Ranking National Ranking
Immunology H-index 58 Citations 12,527 169 World Ranking 1850 National Ranking 67

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Cancer
  • Internal medicine

Jacques J.M. van Dongen mainly investigates Immunology, Molecular biology, Gene rearrangement, B cell and Minimal residual disease. His is doing research in Antigen, Antibody, CD19, Immunophenotyping and Immune system, both of which are found in Immunology. His Molecular biology research incorporates themes from Dendritic cell, Recombination-activating gene, RAG2 and Gene, Severe combined immunodeficiency.

The various areas that he examines in his Gene rearrangement study include Cellular differentiation, T cell, T-cell receptor, Regulation of gene expression and Polymerase chain reaction. His B cell research is multidisciplinary, incorporating elements of DNA and Immunoglobulin heavy chain. His study in Minimal residual disease is interdisciplinary in nature, drawing from both Flow cytometry, Acute lymphocytic leukemia and Oncology.

His most cited work include:

  • Prognostic value of minimal residual disease in acute lymphoblastic leukaemia in childhood (851 citations)
  • Immunophenotyping of blood lymphocytes in childhood: Reference values for lymphocyte subpopulations (594 citations)
  • Molecular response to treatment redefines all prognostic factors in children and adolescents with B-cell precursor acute lymphoblastic leukemia: results in 3184 patients of the AIEOP-BFM ALL 2000 study (509 citations)

What are the main themes of his work throughout his whole career to date?

Immunology, Molecular biology, Antibody, Internal medicine and Immunophenotyping are his primary areas of study. His work in B cell, Bone marrow, Immune system, EuroFlow and Antigen are all subfields of Immunology research. In his study, Polymerase chain reaction is inextricably linked to Gene rearrangement, which falls within the broad field of Molecular biology.

Jacques J.M. van Dongen has researched Internal medicine in several fields, including Surgery and Oncology. In Immunophenotyping, he works on issues like Leukemia, which are connected to Cancer research. The study incorporates disciplines such as Acute lymphocytic leukemia and Transplantation in addition to Minimal residual disease.

He most often published in these fields:

  • Immunology (42.63%)
  • Molecular biology (22.12%)
  • Antibody (19.23%)

What were the highlights of his more recent work (between 2017-2021)?

  • Immunophenotyping (17.95%)
  • Immunology (42.63%)
  • Flow cytometry (10.90%)

In recent papers he was focusing on the following fields of study:

His scientific interests lie mostly in Immunophenotyping, Immunology, Flow cytometry, EuroFlow and Antibody. His research integrates issues of Cancer research, Leukemia and Bone marrow in his study of Immunophenotyping. His Flow cytometry research is multidisciplinary, relying on both Myeloid, Pathology, Lymphocyte, Tissue damage and Multiple myeloma.

His research in EuroFlow intersects with topics in Orientation, Newborn screening and Acute leukemia. Jacques J.M. van Dongen specializes in Antibody, namely B cell. His B cell research integrates issues from Second line treatment, Chronic lymphocytic leukemia, Melphalan and Minimal residual disease.

Between 2017 and 2021, his most popular works were:

  • Age-associated distribution of normal B-cell and plasma cell subsets in peripheral blood (63 citations)
  • Standardized next-generation sequencing of immunoglobulin and T-cell receptor gene recombinations for MRD marker identification in acute lymphoblastic leukaemia; a EuroClonality-NGS validation study (55 citations)
  • Measurable Residual Disease by Next-Generation Flow Cytometry in Multiple Myeloma (44 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Cancer
  • Internal medicine

The scientist’s investigation covers issues in Internal medicine, Oncology, Minimal residual disease, EuroFlow and Flow cytometry. His Internal medicine study integrates concerns from other disciplines, such as Text mining and Fusion gene. His studies in Oncology integrate themes in fields like Survival rate, Clinical endpoint, Randomized controlled trial and Surrogate endpoint.

His Minimal residual disease research is multidisciplinary, incorporating perspectives in Progression-free survival, Chemoimmunotherapy, Primer, Computational biology and DNA sequencing. His work in Flow cytometry addresses subjects such as Cancer research, which are connected to disciplines such as Immunophenotyping. Jacques J.M. van Dongen integrates Viral pathogenesis with Immunology in his research.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Top Publications

Prognostic value of minimal residual disease in acute lymphoblastic leukaemia in childhood

Jacques Jm van Dongen;Taku Seriu;E Renate Panzer-Grümayer;Andrea Biondi.
The Lancet (1998)

1256 Citations

Immunophenotyping of blood lymphocytes in childhood: Reference values for lymphocyte subpopulations

W.Marieke Comans-Bitter;Ronald de Groot;René van den Beemd;Herman J. Neijens.
The Journal of Pediatrics (1997)

925 Citations

Molecular response to treatment redefines all prognostic factors in children and adolescents with B-cell precursor acute lymphoblastic leukemia: results in 3184 patients of the AIEOP-BFM ALL 2000 study

Valentino Conter;Claus R. Bartram;Maria Grazia Valsecchi;Andre Schrauder.
Blood (2010)

777 Citations

An antibody-deficiency syndrome due to mutations in the CD19 gene

Menno C van Zelm;Ismail Reisli;Mirjam van der Burg;Diana Castaño.
The New England Journal of Medicine (2006)

552 Citations

Final Report of the Efficacy and Safety of Gemtuzumab Ozogamicin (Mylotarg) in Patients With CD33-positive Acute Myeloid Leukemia in First Recurrence

Richard A. Larson;Eric L. Sievers;Eric L. Sievers;Edward A. Stadtmauer;Bob Löwenberg.
Cancer (2005)

484 Citations

Increased cell division but not thymic dysfunction rapidly affects the T-cell receptor excision circle content of the naive T cell population in HIV-1 infection.

Mette D. Hazenberg;Sigrid A. Otto;James W.T. Cohen Stuart;Martie C.M. Verschuren.
Nature Medicine (2000)

444 Citations

Targeting of the CD33-calicheamicin immunoconjugate Mylotarg (CMA-676) in acute myeloid leukemia: in vivo and in vitro saturation and internalization by leukemic and normal myeloid cells.

Vincent H. J. van der Velden;Jeroen G. te Marvelde;Patricia G. Hoogeveen;Irwin D. Bernstein.
Blood (2001)

429 Citations

Minimal residual disease diagnostics in acute lymphoblastic leukemia: need for sensitive, fast, and standardized technologies

Jacques J. M. van Dongen;Vincent H. J. van der Velden;Monika Brüggemann;Alberto Orfao.
Blood (2015)

405 Citations

T cell receptor excision circles as markers for recent thymic emigrants: basic aspects, technical approach, and guidelines for interpretation.

Mette D. Hazenberg;Martie C. M. Verschuren;Dörte Hamann;Frank Miedema.
Journal of Molecular Medicine (2001)

401 Citations

New insights on human T cell development by quantitative T cell receptor gene rearrangement studies and gene expression profiling

Willem A. Dik;Karin Pike-Overzet;Floor Weerkamp;Dick de Ridder;Dick de Ridder.
Journal of Experimental Medicine (2005)

390 Citations

Profile was last updated on December 6th, 2021.
Research.com Ranking is based on data retrieved from the Microsoft Academic Graph (MAG).
The ranking h-index is inferred from publications deemed to belong to the considered discipline.

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