World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
73
Citations
18785
World Ranking
5945
National Ranking
150

Overview

Anton W. Langerak is a researcher affiliated with Erasmus University Rotterdam in the Netherlands, active in the field of Medicine with a strong focus on genetics, immunology, and pathology. The body of work encompasses a significant number of publications centered on chronic lymphocytic leukemia (CLL) and related hematological malignancies.

The scientist's research primarily addresses the complex mechanisms underlying CLL as well as lymphoma diagnosis and treatment. Other important topics include immunodeficiency and autoimmune disorders, immune cell function and interaction, acute lymphoblastic leukemia research, cancer genomics and diagnostics, and T-cell and B-cell immunology.

Key publication venues where their work is frequently published include:

  • Blood
  • Leukemia
  • Frontiers in Oncology
  • Blood Cancer Journal
  • Journal of Molecular Diagnostics

Prominent papers authored by or involving Anton W. Langerak include:

  • "Higher-order connections between stereotyped subsets: implications for improved patient classification in CLL" (2020, Blood)
  • "Immunoglobulin gene sequence analysis in chronic lymphocytic leukemia: the 2022 update of the recommendations by ERIC, the European Research Initiative on CLL" (2022, Leukemia)
  • "ACVIM consensus statement guidelines on diagnosing and distinguishing low-grade neoplastic from inflammatory lymphocytic chronic enteropathies in cats" (2023, Journal of Veterinary Internal Medicine)
  • "Next-Generation Sequencing-Based Clonality Assessment of Ig Gene Rearrangements" (2021, Journal of Molecular Diagnostics)
  • "Immunoglobulin gene analysis in chronic lymphocytic leukemia in the era of next generation sequencing" (2020, Leukemia)

Frequent collaborators in research projects and publications include:

  • P. Martijn Kolijn
  • Arnon P. Kater
  • Paul J. Hengeveld
  • Frédéric Davi
  • Mark-David Levin

Their subfields of study span genetics, immunology, pathology and forensic medicine, oncology, and molecular biology, reflecting a broad expertise within biomedical research related to hematology and immunology.

Best Publications

  • Obinutuzumab plus Chlorambucil in Patients with CLL and Coexisting Conditions

    Valentin Goede;Kirsten Fischer;Raymonde Busch;Anja Engelke

  • EuroClonality/BIOMED-2 guidelines for interpretation and reporting of Ig/TCR clonality testing in suspected lymphoproliferations

    A. W. Langerak;P. J. T. A. Groenen;M. Brüggemann;K. Beldjord

  • Stereotyped B-cell receptors in one-third of chronic lymphocytic leukemia: a molecular classification with implications for targeted therapies

    Andreas Agathangelidis;Nikos Darzentas;Anastasia Hadzidimitriou;Xavier Brochet

  • New insights on human T cell development by quantitative T cell receptor gene rearrangement studies and gene expression profiling

    Willem A. Dik;Karin Pike-Overzet;Floor Weerkamp;Dick de Ridder;Dick de Ridder

  • Integrated Transcript and Genome Analyses Reveal NKX2-1 and MEF2C as Potential Oncogenes in T Cell Acute Lymphoblastic Leukemia

    Irene Homminga;Rob Pieters;Anton W. Langerak;Johan J. de Rooi

  • The C-MYB locus is involved in chromosomal translocation and genomic duplications in human T-cell acute leukemia (T-ALL) - the translocation defining a new T-ALL subtype in very young children

    Emmanuelle Clappier;Wendy Cuccuini;Anna Kalota;Antoine Crinquette

  • PHF6 mutations in T-cell acute lymphoblastic leukemia

    Pieter van Vlierberghe;Pieter van Vlierberghe;Pieter van Vlierberghe;Teresa Palomero;Hossein Khiabanian;Joni van der Meulen

  • Molecular and flow cytometric analysis of the Vβ repertoire for clonality assessment in mature TCRαβ T-cell proliferations

    Anton W. Langerak;René van den Beemd;Ingrid L. M. Wolvers-Tettero;Patrick P. C. Boor

  • E2A and EBF act in synergy with the V(D)J recombinase to generate a diverse immunoglobulin repertoire in nonlymphoid cells.

    William J Romanow;Anton W Langerak;Peter Goebel;Ingrid L.M Wolvers-Tettero

  • Improved reliability of lymphoma diagnostics via PCR-based clonality testing: report of the BIOMED-2 Concerted Action BHM4-CT98-3936.

    J H J M van Krieken;A W Langerak;E A Macintyre;M Kneba

  • Fixed Duration of Venetoclax-Rituximab in Relapsed/Refractory Chronic Lymphocytic Leukemia Eradicates Minimal Residual Disease and Prolongs Survival: Post-Treatment Follow-Up of the MURANO Phase III Study

    Arnon P Kater;John F Seymour;Peter Hillmen;Barbara Eichhorst

  • Immunoglobulin gene rearrangements and the pathogenesis of multiple myeloma

    David Gonzalez;Mirjam van der Burg;Ramon Garcia-Sanz;James A. Fenton

  • Selective retention of herpes simplex virus-specific T cells in latently infected human trigeminal ganglia.

    Georges M. G. M. Verjans;Rogier Q. Hintzen;Jessica M. van Dun;Angelique Poot

  • Powerful strategy for polymerase chain reaction-based clonality assessment in T-cell malignancies Report of the BIOMED-2 Concerted Action BHM4 CT98-3936.

    M. Brüggemann;H. White;P. Gaulard;R. Garcia-Sanz

  • Flow cytometric analysis of the Vbeta repertoire in healthy controls.

    René van den Beemd;Patrick P.C. Boor;Ellen G. van Lochem;Wim C.J. Hop

  • Generation of T Cells from Human Embryonic Stem Cell-Derived Hematopoietic Zones

    Frank Timmermans;Imke Velghe;Lieve Vanwalleghem;Magda De Smedt

  • Standardized next-generation sequencing of immunoglobulin and T-cell receptor gene recombinations for MRD marker identification in acute lymphoblastic leukaemia; a EuroClonality-NGS validation study

    Monika Brüggemann;Michaela Kotrová;Henrik Knecht;Jack Bartram

  • Premature aging of circulating T cells in patients with end-stage renal disease

    Michiel G.H. Betjes;Anton W. Langerak;Ashley van der Spek;Elly A. de Wit

  • Distinct gene expression profiles of acute myeloid/T-lymphoid leukemia with silenced CEBPA and mutations in NOTCH1

    Bas J. Wouters;Meritxell Alberich Jordà;Karen Keeshan;Irene Louwers

  • Estimating human age from T-cell DNA rearrangements

    D. Zubakov;F. Liu;M.C. van Zelm;J. Vermeulen

Frequent Co-Authors

Jacques J.M. van Dongen
Jacques J.M. van Dongen Leiden University Medical Center
Frederic Davi
Frederic Davi Assistance Publique – Hôpitaux de Paris
Kostas Stamatopoulos
Kostas Stamatopoulos Centre for Research and Technology Hellas
Richard Rosenquist
Richard Rosenquist Karolinska Institute
Paolo Ghia
Paolo Ghia Vita-Salute San Raffaele University
Šárka Pospíšilová
Šárka Pospíšilová Masaryk University
Michael Hallek
Michael Hallek University of Cologne
Nicholas Chiorazzi
Nicholas Chiorazzi Feinstein Institute for Medical Research
David Oscier
David Oscier Royal Bournemouth Hospital
Stephan Stilgenbauer
Stephan Stilgenbauer University of Ulm

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing Anton W. Langerak

Trending Scientists

Recently Published Articles