Tom Taghon

Best Publications

• A cell atlas of human thymic development defines T cell repertoire formation.

  Jong-Eun Park;Rachel A. Botting;Cecilia Domínguez Conde;Dorin-Mirel Popescu

  824
  Citations

• Stellate Cells, Hepatocytes, and Endothelial Cells Imprint the Kupffer Cell Identity on Monocytes Colonizing the Liver Macrophage Niche

  Johnny Bonnardel;Wouter T’Jonck;Djoere Gaublomme;Robin Browaeys

  569
  Citations

• A novel tumour-suppressor function for the Notch pathway in myeloid leukaemia

  Apostolos Klinakis;Camille Lobry;Omar Abdel-Wahab;Philmo Oh

  443
  Citations

• Developmental and Molecular Characterization of Emerging β- and γδ-Selected Pre-T Cells in the Adult Mouse Thymus

  Tom Taghon;Mary A. Yui;Rashmi Pant;Rochelle A. Diamond

  416
  Citations

• Molecular Genetics of T Cell Development

  Ellen V. Rothenberg;Tom Taghon

  357
  Citations

• PHF6 mutations in T-cell acute lymphoblastic leukemia

  Pieter van Vlierberghe;Pieter van Vlierberghe;Pieter van Vlierberghe;Teresa Palomero;Hossein Khiabanian;Joni van der Meulen

  355
  Citations

• A cooperative microRNA-tumor suppressor gene network in acute T-cell lymphoblastic leukemia (T-ALL)

  Konstantinos J Mavrakis;Joni Van der Meulen;Andrew L Wolfe;Andrew L Wolfe;Xiaoping Liu

  337
  Citations

• ABT-199 mediated inhibition of BCL-2 as a novel therapeutic strategy in T-cell acute lymphoblastic leukemia

  Sofie Peirs;Filip Matthijssens;Steven Goossens;Inge Van de Walle

  291
  Citations

• Generation of T Cells from Human Embryonic Stem Cell-Derived Hematopoietic Zones

  Frank Timmermans;Imke Velghe;Lieve Vanwalleghem;Magda De Smedt

  254
  Citations

• Quantification of reverse transcriptase activity by real-time PCR as a fast and accurate method for titration of HIV, lenti- and retroviral vectors.

  Unknown

  239
  Citations

• Mast cell lineage diversion of T lineage precursors by the essential T cell transcription factor GATA-3

  Tom Taghon;Mary A Yui;Ellen V Rothenberg

  236
  Citations

• Delayed, asynchronous, and reversible T-lineage specification induced by Notch/Delta signaling

  Tom N. Taghon;Elizabeth-Sharon David;Juan Carlos Zúñiga-Pflücker;Ellen V. Rothenberg

  220
  Citations

• The H3K27me3 demethylase UTX is a gender-specific tumor suppressor in T-cell acute lymphoblastic leukemia

  Joni Van der Meulen;Viraj Sanghvi;Konstantinos Mavrakis;Kaat Durinck

  208
  Citations

• Active Form of Notch Imposes T Cell Fate in Human Progenitor Cells

  Magda De Smedt;Katia Reynvoet;Tessa Kerre;Tom Taghon

  147
  Citations

• An early decrease in Notch activation is required for human TCR-αβ lineage differentiation at the expense of TCR-γδ T cells

  Inge Van de Walle;Greet De Smet;Magda De Smedt;Bart Vandekerckhove

  146
  Citations

• A cell atlas of human thymic development defines T cell repertoire formation

  Jong-Eun Park;Rachel A. Botting;Cecilia Domínguez Conde;Dorin-Mirel Popescu

  137
  Citations

• Notch/Delta signaling constrains reengineering of pro-T cells by PU.1.

  Christopher B. Franco;Deirdre D. Scripture-Adams;Irina Proekt;Tom Taghon

  133
  Citations

• Specific Notch receptor–ligand interactions control human TCR-αβ/γδ development by inducing differential Notch signal strength

  Inge Van de Walle;Els Waegemans;Jelle De Medts;Greet De Smet

  128
  Citations

• Integrated scRNA-Seq Identifies Human Postnatal Thymus Seeding Progenitors and Regulatory Dynamics of Differentiating Immature Thymocytes.

  Marieke Lavaert;Kai Ling Liang;Niels Vandamme;Jong-Eun Park

  128
  Citations

• MicroRNA-193b-3p acts as a tumor suppressor by targeting the MYB oncogene in T-cell acute lymphoblastic leukemia

  E Mets;J Van der Meulen;G Van Peer;M Boice

  126
  Citations