World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
96
Citations
30417
World Ranking
1842
National Ranking
1013

Overview

Iannis Aifantis is affiliated with New York University in the United States. Their research primarily spans the fields of Biochemistry, Genetics, and Molecular Biology, as well as Medicine. Within these broad disciplines, Aifantis's work focuses on subfields including Molecular Biology, Immunology, Hematology, Oncology, and Cancer Research.

Their research addresses several main topics, notably:

  • Acute Myeloid Leukemia Research
  • CAR-T cell therapy research
  • Immune Cell Function and Interaction
  • Histone Deacetylase Inhibitors Research
  • Cancer-related molecular mechanisms research
  • RNA modifications and cancer
  • Acute Lymphoblastic Leukemia research

Aifantis has contributed to numerous scientific publications. Their recent papers include:

  • Molecular patterns of response and treatment failure after frontline venetoclax combinations in older patients with AML (2020) published in Blood
  • Epigenetic Silencing of CDR1as Drives IGF2BP3-Mediated Melanoma Invasion and Metastasis (2020) published in Cancer Cell
  • RNA Splicing and Cancer (2020) published in Trends in cancer
  • Three-dimensional chromatin landscapes in T cell acute lymphoblastic leukemia (2020) published in Nature Genetics
  • A RORγt+ cell instructs gut microbiota-specific Treg cell differentiation (2022) published in Nature

The frequent publication venues for Aifantis include:

  • Blood
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Immunology
  • Blood Cancer Discovery
  • Nature Communications

Aifantis often collaborates with several researchers, notably:

  • Aristotelis Tsirigos
  • Matthew T. Witkowski
  • Eric Wang
  • Xufeng Chen
  • Audrey Lasry

Best Publications

  • Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation.

    Kelly Moran-Crusio;Linsey Reavie;Alan Shih;Omar Abdel-Wahab

  • The bone marrow microenvironment at single-cell resolution.

    Anastasia N. Tikhonova;Igor Dolgalev;Hai Hu;Kishor K Sivaraj

  • ASXL1 mutations promote myeloid transformation through loss of PRC2-mediated gene repression.

    Omar Abdel-Wahab;Mazhar Adli;Lindsay M. LaFave;Jie Gao

  • Restoration of TET2 Function Blocks Aberrant Self-Renewal and Leukemia Progression

    Luisa Cimmino;Igor Dolgalev;Yubao Wang;Akihide Yoshimi

  • Genetic inactivation of the polycomb repressive complex 2 in T cell acute lymphoblastic leukemia

    Panagiotis Ntziachristos;Panagiotis Ntziachristos;Aristotelis Tsirigos;Pieter Van Vlierberghe;Jelena Nedjic

  • The SCFFBW7 ubiquitin ligase complex as a tumor suppressor in T cell leukemia

    Benjamin J. Thompson;Silvia Buonamici;Maria Luisa Sulis;Teresa Palomero

  • SRSF2 Mutations Contribute to Myelodysplasia by Mutant-Specific Effects on Exon Recognition

    Eunhee Kim;Janine O. Ilagan;Yang Liang;Gerrit M. Daubner

  • Molecular pathogenesis of T-cell leukaemia and lymphoma

    Iannis Aifantis;Elizabeth Raetz;Silvia Buonamici

  • Molecular patterns of response and treatment failure after frontline venetoclax combinations in older patients with AML.

    C. D. DiNardo;I. S. Tiong;I. S. Tiong;A. Quaglieri;S. MacRaild

  • γ-secretase inhibitors reverse glucocorticoid resistance in T cell acute lymphoblastic leukemia

    Pedro J Real;Valeria Tosello;Teresa Palomero;Teresa Palomero;Mireia Castillo

  • Targeting the NF-kappaB signaling pathway in Notch1-induced T-cell leukemia.

    Tomas Vilimas;Joaquina Mascarenhas;Teresa Palomero;Malay Mandal

  • Genomic analysis identifies new drivers and progression pathways in skin basal cell carcinoma

    Ximena Bonilla;Laurent Parmentier;Bryan King;Fedor Bezrukov;Fedor Bezrukov

  • Genome-wide Mapping and Characterization of Notch-Regulated Long Noncoding RNAs in Acute Leukemia

    Thomas Trimarchi;Thomas Trimarchi;Erhan Bilal;Panagiotis Ntziachristos;Panagiotis Ntziachristos;Giulia Fabbri

  • A novel tumour-suppressor function for the Notch pathway in myeloid leukaemia

    Apostolos Klinakis;Camille Lobry;Omar Abdel-Wahab;Philmo Oh

  • From Fly Wings to Targeted Cancer Therapies: A Centennial for Notch Signaling

    Panagiotis Ntziachristos;Jing Shan Lim;Julien Sage;Iannis Aifantis;Iannis Aifantis

  • Oncogenic and tumor suppressor functions of Notch in cancer: it’s NOTCH what you think

    Camille Lobry;Philmo Oh;Iannis Aifantis

  • Requirement for cyclin D3 in lymphocyte development and T cell leukemias.

    Ewa Sicinska;Iannis Aifantis;Laurent Le Cam;Wojciech Swat

  • Contrasting roles of histone 3 lysine 27 demethylases in acute lymphoblastic leukaemia

    Panagiotis Ntziachristos;Panagiotis Ntziachristos;Aristotelis Tsirigos;G. Grant Welstead;Thomas Trimarchi

  • Deletion of Asxl1 results in myelodysplasia and severe developmental defects in vivo

    Omar Abdel-Wahab;Jie Gao;Mazhar Adli;Anwesha Dey

  • Genome-wideMappingandCharacterization of Notch-Regulated Long Noncoding RNAs in Acute Leukemia

    Thomas Trimarchi;Erhan Bilal;Panagiotis Ntziachristos;Giulia Fabbri

Frequent Co-Authors

Aristotelis Tsirigos
Aristotelis Tsirigos New York University
Omar Abdel-Wahab
Omar Abdel-Wahab Memorial Sloan Kettering Cancer Center
Adolfo A. Ferrando
Adolfo A. Ferrando Columbia University
Ross L. Levine
Ross L. Levine Memorial Sloan Kettering Cancer Center
Harald von Boehmer
Harald von Boehmer Harvard University
Ari Melnick
Ari Melnick Cornell University
Fotini Gounari
Fotini Gounari University of Chicago
Ira J. Goldberg
Ira J. Goldberg New York University
Jane A. Skok
Jane A. Skok New York University
Charles G. Mullighan
Charles G. Mullighan St. Jude Children's Research Hospital

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

If you’re considering studying Biology or Biochemistry in the USA, there are many online degree and certificate programs to complement your career goals. An increasingly popular option is the cheapest online mba healthcare, which provides advanced knowledge in healthcare management and can open the door to leadership roles in biotech and medical organizations.

In terms of specialized career paths, medical coding and billing offer stable job prospects and flexibility. To advance, many professionals pursue a ccs certification, which qualifies you for higher salaries and more complex roles. If you’re curious about the earning potential, explore the latest data on medical.coder salary to see average incomes and growth opportunities in this field.

Considering a job in this area? It’s helpful to weigh all aspects. Discover whether is medical billing and coding a good career for your aspirations, as this field offers advantages like remote work and job security—alongside a few challenges to keep in mind.

Best Scientists Citing Iannis Aifantis

Trending Scientists