What is he best known for?
The fields of study he is best known for:
Iannis Aifantis mainly focuses on Cancer research, Haematopoiesis, Leukemia, Immunology and Signal transduction.
His research in Cancer research intersects with topics in PRC2, Mutation, Progenitor cell, Histone and Hematopoietic stem cell.
His Haematopoiesis study is concerned with Stem cell in general.
He has included themes like Oncogene and Myeloid leukemia in his Leukemia study.
His study on Signal transduction is covered under Cell biology.
His studies deal with areas such as T cell and Molecular biology as well as T-cell leukemia.
His most cited work include:
- Tet2 Loss Leads to Increased Hematopoietic Stem Cell Self-Renewal and Myeloid Transformation (814 citations)
- The SCFFBW7 ubiquitin ligase complex as a tumor suppressor in T cell leukemia (394 citations)
- ASXL1 mutations promote myeloid transformation through loss of PRC2-mediated gene repression. (384 citations)
What are the main themes of his work throughout his whole career to date?
His scientific interests lie mostly in Cancer research, Cell biology, Immunology, Leukemia and Haematopoiesis.
His work deals with themes such as Mutation, Epigenetics and Notch signaling pathway, which intersect with Cancer research.
His Cell biology research incorporates elements of T cell, Ubiquitin, Ubiquitin ligase and Cellular differentiation.
His Immunology study frequently links to other fields, such as Progenitor cell.
His Leukemia research includes themes of Molecular biology and Oncogene.
His Haematopoiesis study deals with the bigger picture of Stem cell.
He most often published in these fields:
- Cancer research (45.83%)
- Cell biology (36.57%)
- Immunology (24.07%)
What were the highlights of his more recent work (between 2017-2021)?
- Cancer research (45.83%)
- Cell biology (36.57%)
- Leukemia (24.07%)
In recent papers he was focusing on the following fields of study:
His main research concerns Cancer research, Cell biology, Leukemia, Cancer and Myeloid leukemia.
His Cancer research study incorporates themes from T cell, Downregulation and upregulation, Germinal center, B cell and Bone marrow.
His research in Cell biology is mostly focused on Stem cell.
His biological study focuses on Haematopoiesis.
The study incorporates disciplines such as Myeloid and Innate immune system in addition to Haematopoiesis.
His studies in Leukemia integrate themes in fields like Precursor cell and DISEASE RELAPSE.
Between 2017 and 2021, his most popular works were:
- The bone marrow microenvironment at single-cell resolution. (221 citations)
- Targeting an RNA-Binding Protein Network in Acute Myeloid Leukemia (79 citations)
- Notch ligand Dll1 mediates cross-talk between mammary stem cells and the macrophageal niche (78 citations)
In his most recent research, the most cited papers focused on:
Iannis Aifantis mainly investigates Cell biology, Cancer research, Stem cell, Epigenetics and Leukemia.
Iannis Aifantis studies Signal transduction, a branch of Cell biology.
He does research in Cancer research, focusing on Melanoma specifically.
His Stem cell research integrates issues from Regulation of gene expression, Transcriptome, Cellular differentiation and Single-cell analysis.
His Epigenetics study combines topics in areas such as Chromatin, CTCF, DNA methylation and Acute leukemia.
His work carried out in the field of Leukemia brings together such families of science as Azacitidine, Mitochondrion and CLPB.
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