Ari Melnick

Research.com Recognitions

• Member of the Association of American Physicians
• Member of the Association of American Physicians
• Member of the Association of American Physicians
• Member of the Association of American Physicians
• Member of the Association of American Physicians

Overview

Best Publications

• Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation.

  Maria E. Figueroa;Omar Abdel-Wahab;Chao Lu;Patrick S. Ward

  3014
  Citations

• Prognostic relevance of integrated genetic profiling in acute myeloid leukemia

  Jay P. Patel;Mithat Gönen;Maria E. Figueroa;Hugo Fernandez

  2336
  Citations

• IDH mutation impairs histone demethylation and results in a block to cell differentiation

  Chao Lu;Patrick S. Ward;Patrick S. Ward;Gurpreet S. Kapoor;Dan Rohle;Dan Rohle

  2109
  Citations

• methylKit: a comprehensive R package for the analysis of genome-wide DNA methylation profiles

  Altuna Akalin;Matthias Kormaksson;Sheng Li;Francine E Garrett-Bakelman

  1912
  Citations

• Deconstructing a Disease: RAR, Its Fusion Partners, and Their Roles in the Pathogenesis of Acute Promyelocytic Leukemia

  Ari Melnick;Jonathan D. Licht

  1548
  Citations

• Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation.

  Kelly Moran-Crusio;Linsey Reavie;Alan Shih;Omar Abdel-Wahab

  1405
  Citations

• Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells

  Jose M. Polo;Susanna Liu;Maria Eugenia Figueroa;Warakorn Kulalert

  1379
  Citations

• The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight.

  Francine E. Garrett-Bakelman;Francine E. Garrett-Bakelman;Manjula Darshi;Stefan J. Green;Ruben C. Gur

  1121
  Citations

• The N 6 -methyladenosine (m 6 A)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells

  Ly P Vu;Brian F Pickering;Yuanming Cheng;Sara Zaccara

  1076
  Citations

• DNA Methylation Signatures Identify Biologically Distinct Subtypes in Acute Myeloid Leukemia

  Maria E. Figueroa;Sanne Lugthart;Yushan Li;Claudia Erpelinck-Verschueren

  1000
  Citations

• A Molecular Roadmap of Reprogramming Somatic Cells into iPS Cells

  Jose M. Polo;Endre Anderssen;Endre Anderssen;Ryan M. Walsh;Benjamin A. Schwarz

  985
  Citations

• EZH2 Is Required for Germinal Center Formation and Somatic EZH2 Mutations Promote Lymphoid Transformation

  Wendy Béguelin;Relja Popovic;Matt Teater;Yanwen Jiang

  967
  Citations

• Recurrent somatic TET2 mutations in normal elderly individuals with clonal hematopoiesis

  Lambert Busque;Jay P Patel;Maria E Figueroa;Aparna Vasanthakumar

  877
  Citations

• ASXL1 mutations promote myeloid transformation through loss of PRC2-mediated gene repression.

  Omar Abdel-Wahab;Mazhar Adli;Lindsay M. LaFave;Jie Gao

  668
  Citations

• IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics

  Masato Sasaki;Christiane B. Knobbe;Christiane B. Knobbe;Joshua C. Munger;Evan F. Lind

  619
  Citations

• DNMT1-interacting RNAs block gene-specific DNA methylation

  Annalisa Di Ruscio;Alexander K. Ebralidze;Touati Benoukraf;Giovanni Amabile

  573
  Citations

• Comparative isoschizomer profiling of cytosine methylation: The HELP assay

  Batbayar Khulan;Reid F. Thompson;Kenny Ye;Melissa J. Fazzari

  472
  Citations

• Outcome of Deferred Initial Therapy in Mantle-Cell Lymphoma

  Peter Martin;Amy Chadburn;Paul Christos;Karen Weil

  418
  Citations

• The histone lysine methyltransferase KMT2D sustains a gene expression program that represses B cell lymphoma development.

  Ana Ortega-Molina;Isaac W. Boss;Andres Canela;Heng Pan

  417
  Citations

• Distinct evolution and dynamics of epigenetic and genetic heterogeneity in acute myeloid leukemia

  Sheng Li;Francine E Garrett-Bakelman;Stephen S Chung;Mathijs A Sanders

  393
  Citations