2014 - Fellow of the American Association for the Advancement of Science (AAAS)
2005 - Fellow of Alfred P. Sloan Foundation
His primary scientific interests are in RNA, Cell biology, Genetics, N6-Methyladenosine and Molecular biology. His studies deal with areas such as RNA methylation, Messenger RNA and Computational biology as well as RNA. His work carried out in the field of Cell biology brings together such families of science as Methylation, Protein biosynthesis, MRNA methylation, Translation and Regulation of gene expression.
His Regulation of gene expression study integrates concerns from other disciplines, such as Three prime untranslated region and Gene expression. Chuan He has included themes like Cancer research and MRNA modification in his N6-Methyladenosine study. In his study, which falls under the umbrella issue of DNA methylation, DNA demethylation is strongly linked to DNA.
Chuan He mostly deals with Cell biology, RNA, DNA, Biochemistry and Genetics. His research investigates the link between Cell biology and topics such as Regulation of gene expression that cross with problems in Transcription. His RNA research includes themes of RNA methylation, N6-Methyladenosine, Molecular biology, Messenger RNA and Computational biology.
His biological study spans a wide range of topics, including 5-Methylcytosine and Genome. His Genetics study focuses on DNA methylation in particular. As part of the same scientific family, Chuan He usually focuses on DNA methylation, concentrating on Epigenetics and intersecting with 5-Hydroxymethylcytosine, Histone and Cancer research.
RNA, Cell biology, DNA, Computational biology and Messenger RNA are his primary areas of study. His RNA research incorporates elements of RNA methylation, N6-Methyladenosine, Gene expression and Demethylase. His research in N6-Methyladenosine intersects with topics in Translation and Epitranscriptomics.
His Gene expression study combines topics from a wide range of disciplines, such as Interferon and Regulation of gene expression. The Cell biology study combines topics in areas such as Methylation, Transcription factor, MRNA modification, RNA polymerase II and Methyltransferase complex. His research in Messenger RNA tackles topics such as Epidermis which are related to areas like Long non-coding RNA.
Chuan He focuses on RNA, Cell biology, Transcription, DNA and Computational biology. His RNA research entails a greater understanding of Genetics. Chuan He interconnects CUL1, Gene expression, Demethylase, Cyclin-dependent kinase 1 and RNA-binding protein in the investigation of issues within Cell biology.
His studies deal with areas such as Regulation of gene expression and Methyltransferase complex as well as Gene expression. His Transcription course of study focuses on Chromatin and N6-Methyladenosine, Embryonic stem cell and Biophysics. His DNA research is multidisciplinary, incorporating perspectives in Mitochondrion, DNA methylation and Chromosome conformation capture.
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Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine
Shinsuke Ito;Li Shen;Qing Dai;Susan C. Wu.
Tet-Mediated Formation of 5-Carboxylcytosine and Its Excision by TDG in Mammalian DNA
Yu-Fei He;Bin-Zhong Li;Zheng Li;Peng Liu.
Gold-catalyzed organic transformations.
Zigang Li;Chad Brouwer;Chuan He.
Chemical Reviews (2008)
N6-methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO.
Guifang Jia;Ye Fu;Xu Zhao;Xu Zhao;Qing Dai.
Nature Chemical Biology (2011)
N6-methyladenosine-dependent regulation of messenger RNA stability
Xiao Wang;Zhike Lu;Adrian Gomez;Gary C. Hon.
ALKBH5 Is a Mammalian RNA Demethylase that Impacts RNA Metabolism and Mouse Fertility
Guanqun Zheng;John Arne Dahl;Yamei Niu;Peter Fedorcsak.
Molecular Cell (2013)
Global Epigenomic Reconfiguration During Mammalian Brain Development
Ryan Lister;Ryan Lister;Eran A. Mukamel;Joseph R. Nery;Mark Urich.
N6-methyladenosine Modulates Messenger RNA Translation Efficiency
Xiao Wang;Xiao Wang;Boxuan Simen Zhao;Boxuan Simen Zhao;Ian A. Roundtree;Ian A. Roundtree;Zhike Lu;Zhike Lu.
A METTL3-METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation
Jianzhao Liu;Yanan Yue;Dali Han;Xiao Wang.
Nature Chemical Biology (2014)
Tet2 Loss Leads to Increased Hematopoietic Stem Cell Self-Renewal and Myeloid Transformation
Kelly Moran-Crusio;Linsey Reavie;Alan Shih;Omar Abdel-Wahab.
Cancer Cell (2011)
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