His scientific interests lie mostly in MRNA methylation, Cell biology, N6-Methyladenosine, Molecular biology and RNA. Much of his study explores MRNA methylation relationship to Epitranscriptomics. His study in Cell biology is interdisciplinary in nature, drawing from both Regulation of gene expression, Gene expression and Protein biosynthesis.
His biological study spans a wide range of topics, including RNA-binding protein and MRNA modification. His research investigates the connection with Molecular biology and areas like Demethylase which intersect with concerns in Gene silencing, Transcription factor, Transcriptome, Messenger RNA and RNA interference. Cell nucleus, Methyltransferase complex and RNA-Directed DNA Methylation is closely connected to RNA methylation in his research, which is encompassed under the umbrella topic of RNA.
His primary areas of study are Cell biology, RNA, Messenger RNA, Genetics and N6-Methyladenosine. His Cell biology study combines topics from a wide range of disciplines, such as Protein biosynthesis, MRNA methylation, Translation, Regulation of gene expression and Methyltransferase complex. His MRNA methylation research is multidisciplinary, incorporating perspectives in RNA methylation, Transcriptome and Demethylase.
He works mostly in the field of RNA, limiting it down to concerns involving Methylation and, occasionally, Ribosomal RNA. His work deals with themes such as Epigenetics, Computational biology and Binding site, which intersect with Messenger RNA. His N6-Methyladenosine research includes elements of Molecular biology and MRNA modification.
The scientist’s investigation covers issues in Methylation, Messenger RNA, Cell biology, Methyltransferase and RNA. His Messenger RNA study also includes
In his study, which falls under the umbrella issue of MRNA modification, Gene expression is strongly linked to RNA-binding protein. The study incorporates disciplines such as Translation, Tumor progression, Transfer RNA and Small nuclear RNA in addition to Protein biosynthesis. The RNA study combines topics in areas such as Complementary DNA, Transcriptome, N6-Methyladenosine and HEK 293 cells.
Zhike Lu mainly focuses on Cell biology, Gene knockdown, Methylation, RNA and Ribosomal RNA. His Cell biology study incorporates themes from Regulation of gene expression, Histone H3, Transcription and MRNA modification. Zhike Lu combines subjects such as Carcinogenesis, Melanoma and Demethylase with his study of Gene knockdown.
His Methylation study integrates concerns from other disciplines, such as Protein biosynthesis, Translation, Messenger RNA and Small nuclear RNA.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
N6-methyladenosine-dependent regulation of messenger RNA stability
Xiao Wang;Zhike Lu;Adrian Gomez;Gary C. Hon.
Nature (2014)
ALKBH5 Is a Mammalian RNA Demethylase that Impacts RNA Metabolism and Mouse Fertility
Guanqun Zheng;John Arne Dahl;Yamei Niu;Peter Fedorcsak.
Molecular Cell (2013)
Identification of 67 Histone Marks and Histone Lysine Crotonylation as a New Type of Histone Modification
Minjia Tan;Hao Luo;Sangkyu Lee;Fulai Jin.
Cell (2011)
N6-methyladenosine Modulates Messenger RNA Translation Efficiency
Xiao Wang;Xiao Wang;Boxuan Simen Zhao;Boxuan Simen Zhao;Ian A. Roundtree;Ian A. Roundtree;Zhike Lu;Zhike Lu.
Cell (2015)
A METTL3-METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation
Jianzhao Liu;Yanan Yue;Dali Han;Xiao Wang.
Nature Chemical Biology (2014)
The diploid genome sequence of an Asian individual.
Jun Wang;Wei Wang;Ruiqiang Li;Ruiqiang Li;Yingrui Li;Yingrui Li;Yingrui Li.
Nature (2008)
m6A Demethylase ALKBH5 Maintains Tumorigenicity of Glioblastoma Stem-like Cells by Sustaining FOXM1 Expression and Cell Proliferation Program.
Sicong Zhang;Boxuan Simen Zhao;Boxuan Simen Zhao;Aidong Zhou;Kangyu Lin.
Cancer Cell (2017)
The first identification of lysine malonylation substrates and its regulatory enzyme
Chao Peng;Zhike Lu;Zhongyu Xie;Zhongyi Cheng.
Molecular & Cellular Proteomics (2011)
YTHDF3 facilitates translation and decay of N6-methyladenosine-modified RNA.
Hailing Shi;Xiao Wang;Xiao Wang;Zhike Lu;Zhike Lu;Boxuan S Zhao;Boxuan S Zhao.
Cell Research (2017)
m6A RNA Methylation Regulates the Self-Renewal and Tumorigenesis of Glioblastoma Stem Cells.
Qi Cui;Hailing Shi;Peng Ye;Li Li.
Cell Reports (2017)
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