2026 Zhike Lu: Molecular Biology Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Molecular Biology	53	2351	2116	1163	1035	71	41535

Overview

Zhike Lu is affiliated with the University of Chicago in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, with a significant focus on molecular biology within that domain. The scientist's work also touches on infectious diseases, cancer research, epidemiology, and electrical and electronic engineering as subfields of study.

The main topics addressed in Zhike Lu's research include:

CRISPR and Genetic Engineering
RNA and protein synthesis mechanisms
RNA modifications and cancer
Advanced biosensing and bioanalysis techniques
Amoebic Infections and Treatments
Cancer-related molecular mechanisms research
Cytomegalovirus and herpesvirus research

Significant recent papers authored or coauthored by Zhike Lu feature the following titles, publication years, and venues:

"A metabolic labeling method detects m6A transcriptome-wide at single base resolution," 2020, Nature Chemical Biology
"m6A demethylase ALKBH5 is required for antibacterial innate defense by intrinsic motivation of neutrophil migration," 2022, Signal Transduction and Targeted Therapy
"The RNA m6A demethylase ALKBH5 drives emergency granulopoiesis and neutrophil mobilization by upregulating G-CSFR expression," 2023, Cellular and Molecular Immunology
"Direct-seq: programmed gRNA scaffold for streamlined scRNA-seq in CRISPR screen," 2020, Genome Biology
"Deep sampling of gRNA in the human genome and deep-learning-informed prediction of gRNA activities," 2023, Cell Discovery

Zhike Lu often collaborates with other researchers, frequently coauthoring papers with:

Lijia Ma
Yini Li
Zhenxing Yu
Yangfan Zhou
Ke Ni

Several publication venues have been notable in Zhike Lu's scholarly output. These include:

Zenodo (CERN European Organization for Nuclear Research)
Cell Reports
Scientific Reports
bioRxiv (Cold Spring Harbor Laboratory)
Nature Chemical Biology

Best Publications

N6-methyladenosine-dependent regulation of messenger RNA stability

Xiao Wang;Zhike Lu;Adrian Gomez;Gary C. Hon

3726
Citations
A METTL3-METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation

Jianzhao Liu;Yanan Yue;Dali Han;Xiao Wang

3392
Citations
ALKBH5 Is a Mammalian RNA Demethylase that Impacts RNA Metabolism and Mouse Fertility

Guanqun Zheng;John Arne Dahl;Yamei Niu;Peter Fedorcsak

3067
Citations
N6-methyladenosine Modulates Messenger RNA Translation Efficiency

Xiao Wang;Xiao Wang;Boxuan Simen Zhao;Boxuan Simen Zhao;Ian A. Roundtree;Ian A. Roundtree;Zhike Lu;Zhike Lu

2920
Citations
Identification of 67 Histone Marks and Histone Lysine Crotonylation as a New Type of Histone Modification

Minjia Tan;Hao Luo;Sangkyu Lee;Fulai Jin

1841
Citations
YTHDF3 facilitates translation and decay of N6-methyladenosine-modified RNA.

Hailing Shi;Xiao Wang;Xiao Wang;Zhike Lu;Zhike Lu;Boxuan S Zhao;Boxuan S Zhao

1509
Citations
m6A Demethylase ALKBH5 Maintains Tumorigenicity of Glioblastoma Stem-like Cells by Sustaining FOXM1 Expression and Cell Proliferation Program.

Sicong Zhang;Boxuan Simen Zhao;Aidong Zhou;Kangyu Lin

1270
Citations
The diploid genome sequence of an Asian individual.

Jun Wang;Wei Wang;Ruiqiang Li;Ruiqiang Li;Yingrui Li;Yingrui Li;Yingrui Li

1157
Citations
m6A RNA Methylation Regulates the Self-Renewal and Tumorigenesis of Glioblastoma Stem Cells

Qi Cui;Hailing Shi;Peng Ye;Li Li

1104
Citations
Ythdc2 is an N6-methyladenosine binding protein that regulates mammalian spermatogenesis.

Phillip J Hsu;Yunfei Zhu;Honghui Ma;Honghui Ma;Yueshuai Guo

830
Citations
METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and Promotes Leukemogenesis via mRNA m6A Modification

Hengyou Weng;Huilin Huang;Huizhe Wu;Xi Qin

818
Citations
RNA m6A methylation regulates the ultraviolet-induced DNA damage response.

Yang Xiang;Benoit Laurent;Benoit Laurent;Chih-Hung Hsu;Chih-Hung Hsu;Sigrid Nachtergaele

800
Citations
The first identification of lysine malonylation substrates and its regulatory enzyme

Chao Peng;Zhike Lu;Zhongyu Xie;Zhongyi Cheng

754
Citations
m 6 A mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer

Jun Liu;Jun Liu;Mark A Eckert;Bryan T Harada;Bryan T Harada;Song-Mei Liu

665
Citations
Structural basis for selective binding of m6A RNA by the YTHDC1 YTH domain

Chao Xu;Xiao Wang;Ke Liu;Ian A Roundtree

642
Citations
Differential m6A, m6Am, and m1A Demethylation Mediated by FTO in the Cell Nucleus and Cytoplasm

Jiangbo Wei;Jiangbo Wei;Fange Liu;Fange Liu;Zhike Lu;Zhike Lu;Zhike Lu;Qili Fei;Qili Fei

639
Citations
Deep RNA sequencing at single base-pair resolution reveals high complexity of the rice transcriptome

Guojie Zhang;Guangwu Guo;Xueda Hu;Yong Zhang

567
Citations
m6A mRNA demethylase FTO regulates melanoma tumorigenicity and response to anti-PD-1 blockade.

Seungwon Yang;Jiangbo Wei;Yan-Hong Cui;Gayoung Park

557
Citations
Histone H3 trimethylation at lysine 36 guides m 6 A RNA modification co-transcriptionally

Huilin Huang;Huilin Huang;Hengyou Weng;Hengyou Weng;Keren Zhou;Tong Wu

551
Citations
m6A-dependent maternal mRNA clearance facilitates zebrafish maternal-to-zygotic transition

Boxuan Simen Zhao;Xiao Wang;Xiao Wang;Alana V. Beadell;Zhike Lu;Zhike Lu

526
Citations

Frequent Co-Authors

Chuan He University of Chicago

Qing Dai University of Chicago

Yingming Zhao University of Chicago

Yang Shi University of Oxford

Guifang Jia Peking University

Guojie Zhang Zhejiang University

Arne Klungland Oslo University Hospital

Yue Chen University of Minnesota

Tao Pan Jinan University

Yujiang Geno Shi Harvard University

External Links

Personal website of Zhike Lu

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