D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 53 Citations 11,663 146 World Ranking 8685 National Ranking 3887

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Gene
  • DNA

His primary areas of investigation include Biochemistry, NAD+ kinase, Nicotinamide adenine dinucleotide, Enzyme and Succinylation. His research in Sirtuin, Escherichia coli, Acetylation, Enzyme kinetics and Histone are components of Biochemistry. His Sirtuin research incorporates elements of Histone H4 and Epigenetics.

Hening Lin regularly links together related areas like Cell biology in his NAD+ kinase studies. His work in Nicotinamide adenine dinucleotide tackles topics such as Myristoylation which are related to areas like Acylation, Fatty acylation and SIRT2. His Enzyme research integrates issues from Siderophore and Enterobactin.

His most cited work include:

  • Succinate is an inflammatory signal that induces IL-1β through HIF-1α (1591 citations)
  • Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase. (809 citations)
  • SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysine (420 citations)

What are the main themes of his work throughout his whole career to date?

His scientific interests lie mostly in Biochemistry, Sirtuin, Enzyme, NAD+ kinase and Cell biology. His Biochemistry research focuses on Fatty acylation, Deacetylase activity, Acetylation, Acylation and Small molecule. His research in Sirtuin focuses on subjects like Cancer, which are connected to Sirtuin 1 and Cytotoxicity.

His Enzyme research incorporates themes from Stereochemistry and Escherichia coli. His NAD+ kinase study combines topics in areas such as Adenosine diphosphate ribose and DNA repair. Hening Lin studied Cell biology and Histone that intersect with Chromatin.

He most often published in these fields:

  • Biochemistry (76.11%)
  • Sirtuin (41.11%)
  • Enzyme (36.11%)

What were the highlights of his more recent work (between 2018-2021)?

  • Sirtuin (41.11%)
  • Biochemistry (76.11%)
  • Cell biology (23.33%)

In recent papers he was focusing on the following fields of study:

His primary scientific interests are in Sirtuin, Biochemistry, Cell biology, Fatty acylation and NAD+ kinase. His work carried out in the field of Sirtuin brings together such families of science as Cancer and Cancer research. Enzyme, Deacetylase activity, Cysteine, Histone and Nicotinamide adenine dinucleotide are among the areas of Biochemistry where the researcher is concentrating his efforts.

His Cell biology research is multidisciplinary, incorporating elements of HEK 293 cells, Transcription and Palmitoylation. His studies deal with areas such as HDAC11, In vitro and Acylation as well as Fatty acylation. As a member of one scientific family, Hening Lin mostly works in the field of NAD+ kinase, focusing on GTPase and, on occasion, RALB, Myristoylation and Transferase.

Between 2018 and 2021, his most popular works were:

  • HDAC11 regulates type I interferon signaling through defatty-acylation of SHMT2 (55 citations)
  • HDAC11 regulates type I interferon signaling through defatty-acylation of SHMT2 (55 citations)
  • Loss of Sirtuin 1 Alters the Secretome of Breast Cancer Cells by Impairing Lysosomal Integrity (47 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Gene
  • DNA

The scientist’s investigation covers issues in Sirtuin, Biochemistry, NAD+ kinase, Cell biology and Fatty acylation. His Sirtuin study combines topics from a wide range of disciplines, such as Cancer, Cancer research and Structure–activity relationship. Specifically, his work in Biochemistry is concerned with the study of HDAC11.

His Cell biology research focuses on Transcription and how it connects with Epigenetics, DNA repair, Signal transduction, Transcription factor and Estrogen receptor. The various areas that Hening Lin examines in his Epigenetics study include Histone deacetylase and Enzyme. His research in Fatty acylation intersects with topics in Ubiquitin, Interferon, Histone deacetylase 5, Histone deacetylase 2 and Deacetylase activity.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Succinate is an inflammatory signal that induces IL-1β through HIF-1α

G. M. Tannahill;A. M. Curtis;J. Adamik;E. M. Palsson-McDermott.
Nature (2013)

1950 Citations

Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase.

Jintang Du;Yeyun Zhou;Xiaoyang Su;Jiu Jiu Yu.
Science (2011)

1005 Citations

SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysine

Hong Jiang;Saba Khan;Yi Wang;Guillaume Charron.
Nature (2013)

557 Citations

Programming peptidomimetic syntheses by translating genetic codes designed de novo

Anthony C. Forster;Zhongping Tan;Madhavi N. L. Nalam;Hening Lin.
Proceedings of the National Academy of Sciences of the United States of America (2003)

329 Citations

How pathogenic bacteria evade mammalian sabotage in the battle for iron.

Michael A Fischbach;Michael A Fischbach;Hening Lin;David R Liu;Christopher T Walsh.
Nature Chemical Biology (2006)

328 Citations

The pathogen-associated iroA gene cluster mediates bacterial evasion of lipocalin 2

Michael A. Fischbach;Hening Lin;Lu Zhou;Yang Yu.
Proceedings of the National Academy of Sciences of the United States of America (2006)

325 Citations

Sirt6 Regulates Tnf-Alpha Secretion Through Hydrolysis of Long-Chain Fatty Acyl Lysine

H Jiang;S Khan;Y Wang;G Charron.
Nature (2013)

233 Citations

Chemical genetic discovery of PARP targets reveals a role for PARP-1 in transcription elongation

Bryan A. Gibson;Yajie Zhang;Hong Jiang;Kristine M. Hussey.
Science (2016)

219 Citations

Screening and selection methods for large-scale analysis of protein function.

Hening Lin;Virginia W. Cornish.
Angewandte Chemie (2002)

211 Citations

A chemoenzymatic approach to glycopeptide antibiotics.

Hening Lin;Christopher T Walsh.
Journal of the American Chemical Society (2004)

196 Citations

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