World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
65
Citations
19246
World Ranking
9020
National Ranking
4009

Overview

Hening Lin is affiliated with the Howard Hughes Medical Institute in the United States. Their research focuses on biochemistry, genetics, and molecular biology, with significant contributions to medicine. The scientist's work primarily explores subfields such as molecular biology, physiology, geriatrics and gerontology, oncology, and epidemiology.

The main topics covered in Lin's research include:

  • Sirtuins and Resveratrol in Medicine
  • Ubiquitin and proteasome pathways
  • Histone Deacetylase Inhibitors Research
  • Calcium signaling and nucleotide metabolism
  • Peptidase Inhibition and Analysis
  • Autophagy in Disease and Therapy
  • PARP inhibition in cancer therapy

Lin has published extensively in notable scientific venues. The most frequent publication venues are:

  • ACS Chemical Biology
  • Proceedings of the National Academy of Sciences
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of the American Chemical Society
  • Biochemistry

Recent publications demonstrate the scope and themes of Lin's work:

  • "A STAT3 palmitoylation cycle promotes TH17 differentiation and colitis", 2020, Nature
  • "Understanding the Function of Mammalian Sirtuins and Protein Lysine Acylation", 2021, Annual Review of Biochemistry
  • "TiPARP forms nuclear condensates to degrade HIF-1α and suppress tumorigenesis", 2020, Proceedings of the National Academy of Sciences
  • "NMT1 and NMT2 are lysine myristoyltransferases regulating the ARF6 GTPase cycle", 2020, Nature Communications
  • "Altered succinylation of mitochondrial proteins, APP and tau in Alzheimer's disease", 2022, Nature Communications

Among frequent collaborators, Lin has coauthored multiple works with:

  • Jun Young Hong
  • Min Yang
  • Xuan Lü
  • Sadhan Jana
  • Garrison Komaniecki

Best Publications

  • Succinate is an inflammatory signal that induces IL-1β through HIF-1α

    G. M. Tannahill;A. M. Curtis;J. Adamik;E. M. Palsson-McDermott

  • Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase.

    Jintang Du;Yeyun Zhou;Xiaoyang Su;Jiu Jiu Yu

  • SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysine

    Hong Jiang;Saba Khan;Yi Wang;Guillaume Charron

  • Protein Lipidation: Occurrence, Mechanisms, Biological Functions, and Enabling Technologies.

    Hong Jiang;Xiaoyu Zhang;Xiao Chen;Pornpun Aramsangtienchai

  • The pathogen-associated iroA gene cluster mediates bacterial evasion of lipocalin 2

    Michael A. Fischbach;Hening Lin;Lu Zhou;Yang Yu

  • How pathogenic bacteria evade mammalian sabotage in the battle for iron.

    Michael A Fischbach;Hening Lin;David R Liu;Christopher T Walsh

  • Chemical genetic discovery of PARP targets reveals a role for PARP-1 in transcription elongation

    Bryan A. Gibson;Yajie Zhang;Hong Jiang;Kristine M. Hussey

  • Programming peptidomimetic syntheses by translating genetic codes designed de novo

    Anthony C. Forster;Zhongping Tan;Madhavi N. L. Nalam;Hening Lin

  • Metabolomics-assisted proteomics identifies succinylation and SIRT5 as important regulators of cardiac function.

    Sushabhan Sadhukhan;Xiaojing Liu;Dongryeol Ryu;Ornella D. Nelson

  • Sirtuins in Epigenetic Regulation

    Hui Jing;Hening Lin

  • The Substrate Specificity of Sirtuins

    Poonam Bheda;Hui Jing;Cynthia Wolberger;Hening Lin;Hening Lin

  • Identification of lysine succinylation substrates and the succinylation regulatory enzyme CobB in Escherichia coli.

    Gozde Colak;Zhongyu Xie;Anita Y. Zhu;Lunzhi Dai

  • Sirt6 Regulates Tnf-Alpha Secretion Through Hydrolysis of Long-Chain Fatty Acyl Lysine

    H Jiang;S Khan;Y Wang;G Charron

  • A SIRT2-Selective Inhibitor Promotes c-Myc Oncoprotein Degradation and Exhibits Broad Anticancer Activity

    Hui Jing;Jing Hu;Bin He;Yashira L. Negrón Abril

  • Protein lysine acylation and cysteine succination by intermediates of energy metabolism

    Hening Lin;Xiaoyang Su;Bin He

  • Screening and selection methods for large-scale analysis of protein function.

    Hening Lin;Virginia W. Cornish

  • Diphthamide biosynthesis requires an organic radical generated by an iron–sulphur enzyme

    Yang Zhang;Xuling Zhu;Andrew T. Torelli;Michael Lee

  • Investigating the ADP-ribosyltransferase Activity of Sirtuins with NAD Analogues and 32P-NAD†

    Jintang Du;Hong Jiang;Hening Lin

  • A chemoenzymatic approach to glycopeptide antibiotics.

    Hening Lin;Christopher T Walsh

  • In Vitro Characterization of Salmochelin and Enterobactin Trilactone Hydrolases IroD, IroE, and Fes

    Hening Lin;Michael A. Fischbach;David R. Liu;Christopher T. Walsh

Frequent Co-Authors

Hong Jiang
Hong Jiang Nanjing Tech University
Quan Hao
Quan Hao University of Hong Kong
Hui Jing
Hui Jing Hunan Normal University
Virginia W. Cornish
Virginia W. Cornish Columbia University
Christopher T. Walsh
Christopher T. Walsh Stanford University
Michael A. Fischbach
Michael A. Fischbach Stanford University
Richard A. Cerione
Richard A. Cerione Cornell University
Sheng Zhang
Sheng Zhang Cornell University
Jack H. Freed
Jack H. Freed Cornell University
David R. Liu
David R. Liu Broad Institute

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring a career in Biology and Biochemistry opens doors to various pathways in healthcare and research. Many students keen to enter the medical field consider starting as medical assistants. Flexible options like financial aid for medical assistant programs make entry more accessible, allowing you to study online with lower upfront costs.

For those seeking to advance, bridge programs are popular. You can transition to licensed practical nursing through cma to lpn bridge programs online, building on your existing credentials while working. If your goal is a deeper understanding of biological sciences, enrolling in an online biology degree offers flexibility and specialization opportunities.

Nursing is another rewarding field for biology graduates. Programs such as online asn programs can help fast-track your entry into professional nursing roles. Overall, these options provide multiple online pathways for advancing your education and shaping a career in healthcare or scientific research.

Best Scientists Citing Hening Lin

Trending Scientists