What is he best known for?
The fields of study he is best known for:
His primary areas of investigation include Biochemistry, Sirtuin, SIRT3, SIRT5 and Mitochondrion.
His Acetylation and NAD+ kinase study are his primary interests in Biochemistry.
His NAD+ kinase study incorporates themes from Histone, Transcriptional regulation and Kidney metabolism.
His Sirtuin study integrates concerns from other disciplines, such as Lysine and Metabolism.
His studies in SIRT3 integrate themes in fields like Calorie restriction, Oxidative stress, Reactive oxygen species, Cell biology and Insulin resistance.
His studies deal with areas such as Apoptosis and Model organism as well as Cell biology.
His most cited work include:
- SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation (1093 citations)
- Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation. (884 citations)
- Calorie Restriction Reduces Oxidative Stress by SIRT3-Mediated SOD2 Activation (878 citations)
What are the main themes of his work throughout his whole career to date?
His main research concerns Biochemistry, Mitochondrion, Sirtuin, SIRT3 and Cell biology.
His research in NAD+ kinase, Acetylation, SIRT5, Lysine and Metabolism are components of Biochemistry.
His work in Mitochondrion addresses subjects such as Oxidative phosphorylation, which are connected to disciplines such as Metabolite.
He works mostly in the field of Sirtuin, limiting it down to concerns involving Pharmacology and, occasionally, Nicotinamide mononucleotide.
His SIRT3 research integrates issues from Calorie restriction, Internal medicine, Endocrinology, Frataxin and Deacetylase activity.
His biological study spans a wide range of topics, including Beta oxidation, Caenorhabditis elegans, Metabolic pathway and Longevity.
He most often published in these fields:
- Biochemistry (50.98%)
- Mitochondrion (38.24%)
- Sirtuin (33.33%)
What were the highlights of his more recent work (between 2019-2021)?
- Cell biology (27.45%)
- Breast cancer (6.86%)
- Cancer research (8.82%)
In recent papers he was focusing on the following fields of study:
The scientist’s investigation covers issues in Cell biology, Breast cancer, Cancer research, Caenorhabditis elegans and Context.
Matthew D. Hirschey interconnects Amino acid, Cell, Saccharomyces cerevisiae and Longevity in the investigation of issues within Cell biology.
His Breast cancer research includes themes of Oxidative stress, In vitro and Downregulation and upregulation.
The study incorporates disciplines such as Transcription factor, In vitro toxicology, Mammary tumor and Oncogene in addition to Cancer research.
His research in Caenorhabditis elegans intersects with topics in Reactive oxygen species, Nuclear DNA, Mitochondrial DNA, Metabolic pathway and Mitochondrion.
Reactive oxygen species and Bioenergetics are commonly linked in his work.
Between 2019 and 2021, his most popular works were:
- NRF2 activation promotes the recurrence of dormant tumour cells through regulation of redox and nucleotide metabolism (13 citations)
- NRF2 activation promotes the recurrence of dormant tumour cells through regulation of redox and nucleotide metabolism (13 citations)
- A cell-nonautonomous mechanism of yeast chronological aging regulated by caloric restriction and one-carbon metabolism. (1 citations)
In his most recent research, the most cited papers focused on:
Cell biology, Longevity, Yeast, Growth medium and Saccharomyces cerevisiae are his primary areas of study.
Matthew D. Hirschey integrates Cell biology and Mechanism in his research.
As part of his studies on Longevity, Matthew D. Hirschey often connects relevant subjects like AMP-activated protein kinase.
This overview was generated by a machine learning system which analysed the scientist’s
body of work. If you have any feedback, you can
contact us
here.
