D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 59 Citations 27,902 113 World Ranking 5831 National Ranking 2750

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Cancer

Raul Mostoslavsky spends much of his time researching Biochemistry, Cell biology, Histone deacetylase, Sirtuin 1 and Sirtuin. His work on Mitochondrion and Deacetylase activity as part of his general Biochemistry study is frequently connected to Fatty acylation, Myristoylation and Acylation, thereby bridging the divide between different branches of science. His work focuses on many connections between Cell biology and other disciplines, such as Transcription factor, that overlap with his field of interest in Protein deacetylase.

His Histone deacetylase study integrates concerns from other disciplines, such as Bioinformatics, Carcinogenesis, SIRT6, Chromatin and Anaerobic glycolysis. The various areas that he examines in his Sirtuin 1 study include Glutamine, Regulation of gene expression, Glutamate dehydrogenase and Metabolism. His Sirtuin research includes themes of Genomic Stability, Stress resistance, Computational biology and Cell fate determination.

His most cited work include:

  • Stress-Dependent Regulation of FOXO Transcription Factors by the SIRT1 Deacetylase (2503 citations)
  • Genomic Instability and Aging-like Phenotype in the Absence of Mammalian SIRT6 (1156 citations)
  • Recent progress in the biology and physiology of sirtuins (1061 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of investigation include Cell biology, Cancer research, SIRT6, Chromatin and Histone deacetylase. His studies deal with areas such as Sirtuin, DNA damage, Genome instability, Epigenetics and Metabolism as well as Cell biology. His work in Sirtuin tackles topics such as Inflammation which are related to areas like Tumor necrosis factor alpha.

SIRT6 is a subfield of Biochemistry that Raul Mostoslavsky explores. The Chromatin study combines topics in areas such as Calorie restriction, Histone, Cellular homeostasis and Disease. His Histone deacetylase research is multidisciplinary, incorporating elements of Histone H3 and microRNA.

He most often published in these fields:

  • Cell biology (46.84%)
  • Cancer research (31.65%)
  • SIRT6 (28.48%)

What were the highlights of his more recent work (between 2015-2021)?

  • Cell biology (46.84%)
  • Cancer research (31.65%)
  • Histone deacetylase (31.01%)

In recent papers he was focusing on the following fields of study:

Raul Mostoslavsky mostly deals with Cell biology, Cancer research, Histone deacetylase, SIRT6 and Epigenetics. His study in Cell biology is interdisciplinary in nature, drawing from both Chromatin, Histone methyltransferase, DNA damage, DNA repair and Cellular homeostasis. His DNA damage study contributes to a more complete understanding of Biochemistry.

His biological study spans a wide range of topics, including Histone H3 and Sirtuin. His SIRT6 research is multidisciplinary, incorporating perspectives in Cancer cell, Cancer, Neurodegeneration, Neuroprotection and Bone marrow. His research in Epigenetics intersects with topics in Histone, DNA methylation and Metabolism.

Between 2015 and 2021, his most popular works were:

  • Interplay between Metabolism and Epigenetics: A Nuclear Adaptation to Environmental Changes (188 citations)
  • Interplay between Metabolism and Epigenetics: A Nuclear Adaptation to Environmental Changes (188 citations)
  • SIRT6 Suppresses Pancreatic Cancer through Control of Lin28b (139 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Cancer

His primary areas of study are Cell biology, Epigenetics, Histone deacetylase, Cancer research and DNA methylation. His Cell biology study incorporates themes from Chromatin and Ubiquitin. His work carried out in the field of Epigenetics brings together such families of science as Histone and Human multitasking.

Histone deacetylase is closely attributed to SIRT6 in his research. His Cancer research research also works with subjects such as

  • Chromatin remodeling, microRNA, Bioinformatics, HMGA2 and Sirtuin most often made with reference to Carcinogenesis,
  • Stem cell, SOX2, Stomach, Progenitor cell and Cell growth most often made with reference to Immunology. His research on DNA methylation concerns the broader Genetics.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Stress-Dependent Regulation of FOXO Transcription Factors by the SIRT1 Deacetylase

Anne Brunet;Lora B. Sweeney;J. Fitzhugh Sturgill;Katrin F. Chua.
Science (2004)

3289 Citations

Genomic Instability and Aging-like Phenotype in the Absence of Mammalian SIRT6

Raul Mostoslavsky;Katrin F. Chua;Katrin F. Chua;David B. Lombard;Wendy W. Pang.
Cell (2006)

1497 Citations

Recent progress in the biology and physiology of sirtuins

Toren Finkel;Chu Xia Deng;Raul Mostoslavsky.
Nature (2009)

1408 Citations

Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC‐1α

Zachary Gerhart-Hines;Zachary Gerhart-Hines;Joseph T. Rodgers;Joseph T. Rodgers;Olivia Bare;Carles Lerin;Carles Lerin.
The EMBO Journal (2007)

1255 Citations

A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy

In Hye Lee;Liu Cao;Raul Mostoslavsky;David B. Lombard.
Proceedings of the National Academy of Sciences of the United States of America (2008)

1218 Citations

SIRT1 Regulates Circadian Clock Gene Expression through PER2 Deacetylation

Gad Asher;David Gatfield;Markus Stratmann;Hans Reinke.
Cell (2008)

1197 Citations

Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice

Hwei-Ling Cheng;Raul Mostoslavsky;Shin'ichi Saito;John P. Manis.
Proceedings of the National Academy of Sciences of the United States of America (2003)

1188 Citations

SIRT4 Inhibits Glutamate Dehydrogenase and Opposes the Effects of Calorie Restriction in Pancreatic β Cells

Marcia C. Haigis;Raul Mostoslavsky;Kevin M. Haigis;Kamau Fahie.
Cell (2006)

1149 Citations

Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation.

David B. Lombard;Frederick W. Alt;Hwei Ling Cheng;Jakob Bunkenborg.
Molecular and Cellular Biology (2007)

1140 Citations

DNA Repair, Genome Stability, and Aging

David B. Lombard;Katrin F. Chua;Raul Mostoslavsky;Sonia Franco.
Cell (2005)

944 Citations

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