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D-Index & Metrics

Biology and Biochemistry

D-Index
55
Citations
23910
World Ranking
14742
National Ranking
269

Overview

Carles Cantó is affiliated with Nestlé (Switzerland) and has contributed extensively to biomedical research with a focus on molecular mechanisms related to aging, metabolism, and muscle physiology.

Their research spans several fields including Medicine and Biochemistry, Genetics and Molecular Biology. Subfields prominently represented in their work include Physiology, Geriatrics and Gerontology, Molecular Biology, Oncology, and Biological Psychiatry.

Key topics explored by Carles Cantó encompass:

  • Sirtuins and Resveratrol in Medicine
  • Calcium signaling and nucleotide metabolism
  • PARP inhibition in cancer therapy
  • Adipose Tissue and Metabolism
  • Muscle Physiology and Disorders
  • Tryptophan and brain disorders
  • Nutrition and Health in Aging

Carles Cantó has authored multiple papers, including:

  • Trigonelline is an NAD+ precursor that improves muscle function during ageing and is reduced in human sarcopenia, 2024, Nature Metabolism
  • Reduced nicotinamide mononucleotide is a new and potent NAD+ precursor in mammalian cells and mice, 2021, The FASEB Journal
  • Crosstalk between Drp1 phosphorylation sites during mitochondrial remodeling and their impact on metabolic adaptation, 2021, Cell Reports
  • A bioluminescent-based probe for in vivo non-invasive monitoring of nicotinamide riboside uptake reveals a link between metastasis and NAD+ metabolism, 2022, Biosensors and Bioelectronics
  • Balancing NAD+ deficits with nicotinamide riboside: therapeutic possibilities and limitations, 2022, Cellular and Molecular Life Sciences

The scientist frequently publishes in notable scientific journals such as Nature Metabolism, The FASEB Journal, Cell Reports, Biosensors and Bioelectronics, and Cellular and Molecular Life Sciences.

Collaboration is a significant aspect of Carles Cantó's work. Frequent co-authors include José Luis Sánchez, Maria Pilar Giner, Sofia Moco, Magali Joffraud, and Marie E. Migaud, indicating a network of scientific partnerships often centered around metabolic and molecular biology research themes.

Best Publications

  • AMPK regulates energy expenditure by modulating NAD + metabolism and SIRT1 activity

    Carles Cantó;Zachary Gerhart-Hines;Jerome N. Feige;Marie Lagouge

  • PGC-1alpha, SIRT1 and AMPK, an energy sensing network that controls energy expenditure.

    Carles Cantó;Johan Auwerx

  • NAD(+) Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus.

    Carles Cantó;Keir J. Menzies;Johan Auwerx

  • The NAD+ precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet induced obesity

    Carles Cantó;Riekelt H. Houtkooper;Eija Pirinen;Eija Pirinen;Dou Y. Youn

  • The NAD+/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling

    Laurent Mouchiroud;Riekelt H. Houtkooper;Norman Moullan;Elena Katsyuba

  • Interdependence of AMPK and SIRT1 for Metabolic Adaptation to Fasting and Exercise in Skeletal Muscle

    Carles Cantó;Lake Q. Jiang;Atul S. Deshmukh;Chikage Mataki

  • The secret life of NAD+: an old metabolite controlling new metabolic signaling pathways.

    Riekelt H. Houtkooper;Carles Cantó;Ronald J. Wanders;Johan Auwerx

  • Specific SIRT1 Activation Mimics Low Energy Levels and Protects against Diet-Induced Metabolic Disorders by Enhancing Fat Oxidation

    Jérôme N. Feige;Marie Lagouge;Carles Canto;Axelle Strehle

  • PARP-1 inhibition increases mitochondrial metabolism through SIRT1 activation

    Péter Bai;Péter Bai;Carles Cantó;Hugues Oudart;Attila Brunyánszki

  • The metabolic footprint of aging in mice

    Riekelt H. Houtkooper;Carmen Argmann;Sander M. Houten;Carles Cantó

  • Caloric restriction, SIRT1 and longevity.

    Carles Cantó;Johan Auwerx

  • AMP-activated protein kinase and its downstream transcriptional pathways.

    Carles Cantó;Johan Auwerx

  • The Molecular Targets of Resveratrol

    Sameer S. Kulkarni;Carles Cantó

  • Targeting Sirtuin 1 to Improve Metabolism: All You Need Is NAD+?

    Carles Cantó;Johan Auwerx

  • Calorie restriction: is AMPK a key sensor and effector?

    Carles Cantó;Johan Auwerx

  • NRK1 controls nicotinamide mononucleotide and nicotinamide riboside metabolism in mammalian cells

    Joanna Ratajczak;Magali Joffraud;Samuel A. J. Trammell;Rosa Ras

  • The role of PARP-1 and PARP-2 enzymes in metabolic regulation and disease.

    Péter Bai;Carles Cantó

  • SRT1720 improves survival and healthspan of obese mice

    Robin K. Minor;Joseph A. Baur;Ana P. Gomes;Theresa M. Ward

  • Deficient Endoplasmic Reticulum-Mitochondrial Phosphatidylserine Transfer Causes Liver Disease

    María Isabel Hernández-Alvarez;David Sebastián;David Sebastián;Sara Vives;Saška Ivanova;Saška Ivanova

  • NCoR1 Is a Conserved Physiological Modulator of Muscle Mass and Oxidative Function

    Hiroyasu Yamamoto;Evan G. Williams;Laurent Mouchiroud;Carles Cantó

Frequent Co-Authors

Johan Auwerx
Johan Auwerx École Polytechnique Fédérale de Lausanne
Riekelt H. Houtkooper
Riekelt H. Houtkooper University of Amsterdam
Kristina Schoonjans
Kristina Schoonjans École Polytechnique Fédérale de Lausanne
Anthony A. Sauve
Anthony A. Sauve Cornell University
Antonio Zorzano
Antonio Zorzano University of Barcelona
Manuel Palacín
Manuel Palacín Institute for Research in Biomedicine
Sander M. Houten
Sander M. Houten Icahn School of Medicine at Mount Sinai
Tatiana V. Petrova
Tatiana V. Petrova University of Lausanne
Carmen Sandi
Carmen Sandi École Polytechnique Fédérale de Lausanne
Hubert Vidal
Hubert Vidal Claude Bernard University Lyon 1

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