Anthony A. Sauve

Overview

Best Publications

• The NAD+ precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet induced obesity

  Carles Cantó;Riekelt H. Houtkooper;Eija Pirinen;Eija Pirinen;Dou Y. Youn

  1308
  Citations

• Nutrient-Sensitive Mitochondrial NAD+ Levels Dictate Cell Survival

  Hongying Yang;Tianle Yang;Joseph A. Baur;Evelyn Perez

  1090
  Citations

• The Biochemistry of Sirtuins

  Anthony A. Sauve;Cynthia Wolberger;Vern L. Schramm;Jef D. Boeke

  930
  Citations

• Glucose Restriction Inhibits Skeletal Myoblast Differentiation by Activating SIRT1 through AMPK-Mediated Regulation of Nampt

  Marcella Fulco;Yana Cen;Po Zhao;Eric P. Hoffman

  882
  Citations

• PARP-1 inhibition increases mitochondrial metabolism through SIRT1 activation

  Péter Bai;Péter Bai;Carles Cantó;Hugues Oudart;Attila Brunyánszki

  848
  Citations

• Neuronal SIRT1 Activation as a Novel Mechanism Underlying the Prevention of Alzheimer Disease Amyloid Neuropathology by Calorie Restriction

  Weiping Qin;Tianle Yang;Lap Ho;Lap Ho;Zhong Zhao

  726
  Citations

• Nicotinamide N -methyltransferase knockdown protects against diet-induced obesity

  Daniel Kraus;Qin Yang;Dong Kong;Alexander S. Banks

  461
  Citations

• Nicotinamide riboside restores cognition through an upregulation of proliferator-activated receptor-γ coactivator 1α regulated β-secretase 1 degradation and mitochondrial gene expression in Alzheimer's mouse models

  Bing Gong;Yong Pan;Prashant Vempati;Wei Zhao

  427
  Citations

• NAD(+) metabolism: Bioenergetics, signaling and manipulation for therapy.

  Yue Yang;Anthony A. Sauve

  424
  Citations

• SIRT1 deacetylation and repression of p300 involves lysine residues 1020/1024 within the cell cycle regulatory domain 1.

  Toula Bouras;Maofu Fu;Anthony A. Sauve;Fang Wang

  422
  Citations

• NAD+ and Vitamin B3: From metabolism to therapies

  Anthony A. Sauve

  385
  Citations

• Chemistry of gene silencing: the mechanism of NAD+-dependent deacetylation reactions.

  Anthony A. Sauve;Ivana Celic;Jose Avalos;Haiteng Deng

  382
  Citations

• Eliciting the mitochondrial unfolded protein response by nicotinamide adenine dinucleotide repletion reverses fatty liver disease in mice

  Karim Gariani;Keir J. Menzies;Dongryeol Ryu;Casey J. Wegner

  364
  Citations

• NAD+-Dependent Activation of Sirt1 Corrects the Phenotype in a Mouse Model of Mitochondrial Disease

  Raffaele Cerutti;Eija Pirinen;Eija Pirinen;Costanza Lamperti;Silvia Marchet

  362
  Citations

• Sir2 Regulation by Nicotinamide Results from Switching between Base Exchange and Deacetylation Chemistry

  Anthony A. Sauve;Vern L. Schramm

  306
  Citations

• Nicotinamide Improves Aspects of Healthspan, but Not Lifespan, in Mice

  Sarah J. Mitchell;Michel Bernier;Miguel A. Aon;Sonia Cortassa

  295
  Citations

• Hormonal Control of Androgen Receptor Function through SIRT1

  Maofu Fu;Manran Liu;Anthony A. Sauve;Xuanmao Jiao

  294
  Citations

• Lethal Cardiomyopathy in Mice Lacking Transferrin Receptor in the Heart

  Wenjing Xu;Tomasa Barrientos;Lan Mao;Howard A. Rockman

  293
  Citations

• PARP-2 Regulates SIRT1 Expression and Whole-Body Energy Expenditure

  Péter Bai;Péter Bai;Carles Canto;Attila Brunyánszki;Aline Huber

  291
  Citations

• Activation of SIRT3 by the NAD+ Precursor Nicotinamide Riboside Protects from Noise-Induced Hearing Loss

  Kevin D. Brown;Sadia Maqsood;Jing Yi Huang;Yong Pan

  285
  Citations