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Biology and Biochemistry

D-Index
46
Citations
8841
World Ranking
18902
National Ranking
7719

Overview

Lap Ho is a researcher affiliated with the Icahn School of Medicine at Mount Sinai in the United States. Their work spans several areas within medicine, with a focus on neurology, psychiatry and mental health, nutrition and dietetics, molecular biology, and physiology.

The scientist has contributed to topics including:

  • Fibromyalgia and Chronic Fatigue Syndrome Research
  • Vitamin C and Antioxidants Research
  • Medicinal Plants and Bioactive Compounds
  • Parkinson's Disease Mechanisms and Treatments
  • Botulinum Toxin and Related Neurological Disorders
  • Alzheimer's Disease Research and Treatments

Recent publications by Lap Ho include:

  • "Gut Microbiome-Modified Polyphenolic Compounds Inhibit α-Synuclein Seeding and Spreading in α-Synucleinopathies," 2020, Frontiers in Neuroscience
  • "Safety, Tolerability and Efficacy of Dietary Supplementation with Concord Grape Juice in Gulf War Veterans with Gulf War Illness: A Phase I/IIA, Randomized, Double-Blind, Placebo-Controlled Trial," 2020, International Journal of Environmental Research and Public Health
  • "Densities and Fertilizer Dosages based Study on the Development and Yield of Solanum procumbens Lour. in the Central Vietnam," 2024, Indian Journal of Agricultural Research
  • "Evaluation of propagation methods using seeds and cuttings in Solanum procumbens (Lour.)," 2025, Research on Crops

The regular publication venues for their work include the International Journal of Environmental Research and Public Health, Frontiers in Neuroscience, Indian Journal of Agricultural Research, and Research on Crops.

Lap Ho frequently collaborates with several co-authors such as:

  • Giulio Maria Pasinetti
  • Hoan Nguyen Van
  • Dang-Vu Thi Thanh
  • Drew A. Helmer
  • William W. Van Doren

Best Publications

  • Diet-induced insulin resistance promotes amyloidosis in a transgenic mouse model of Alzheimer’s disease

    Lap Ho;Weiping Qin;Patrick N. Pompl;Zhongmin Xiang

  • Neuronal SIRT1 Activation as a Novel Mechanism Underlying the Prevention of Alzheimer Disease Amyloid Neuropathology by Calorie Restriction

    Weiping Qin;Tianle Yang;Lap Ho;Lap Ho;Zhong Zhao

  • Grape-derived polyphenolics prevent Abeta oligomerization and attenuate cognitive deterioration in a mouse model of Alzheimer's disease.

    Jun Wang;Lap Ho;Wei Zhao;Kenjiro Ono

  • Nicotinamide riboside restores cognition through an upregulation of proliferator-activated receptor-γ coactivator 1α regulated β-secretase 1 degradation and mitochondrial gene expression in Alzheimer's mouse models

    Bing Gong;Yong Pan;Prashant Vempati;Wei Zhao

  • PGC-1α Expression Decreases in the Alzheimer Disease Brain as a Function of Dementia

    Weiping Qin;Vahram Haroutunian;Pavel Katsel;Christopher P. Cardozo

  • Moderate consumption of Cabernet Sauvignon attenuates Abeta neuropathology in a mouse model of Alzheimer's disease.

    Jun Wang;Lap Ho;Zhong Zhao;Ilana Seror

  • Valsartan lowers brain β-amyloid protein levels and improves spatial learning in a mouse model of Alzheimer disease

    Jun Wang;Lap Ho;Linghong Chen;Zhong Zhao

  • Caloric restriction attenuates β-amyloid neuropathology in a mouse model of Alzheimer’s disease

    Jun Wang;Lap Ho;Weiping Qin;Anne B. Rocher

  • A ketogenic diet as a potential novel therapeutic intervention in amyotrophic lateral sclerosis

    Zhong Zhao;Dale J Lange;Andrei Voustianiouk;Donal MacGrogan

  • Protective roles of intestinal microbiota derived short chain fatty acids in Alzheimer’s disease-type beta-amyloid neuropathological mechanisms

    Lap Ho;Kenjiro Ono;Mayumi Tsuji;Paolo Mazzola

  • Bioavailability of Gallic Acid and Catechins from Grape Seed Polyphenol Extract is Improved by Repeated Dosing in Rats: Implications for Treatment in Alzheimer's Disease

    Mario G. Ferruzzi;Jessica K. Lobo;Elsa M. Janle;Bruce Cooper

  • REGIONAL DISTRIBUTION OF CYCLOOXYGENASE-2 IN THE HIPPOCAMPAL FORMATION IN ALZHEIMER'S DISEASE

    Lap Ho;Cristiana Pieroni;David Winger;Dushyant P. Purohit

  • Potentiation of excitotoxicity in transgenic mice overexpressing neuronal cyclooxygenase-2.

    Kevin A. Kelley;Lap Ho;David Winger;Jose Freire-Moar

  • Roles of Resveratrol and Other Grape-Derived Polyphenols in Alzheimer’s Disease Prevention and Treatment

    Giulio Maria Pasinetti;Jun Wang;Lap Ho;Lap Ho;Wei Zhao;Wei Zhao

  • Cytokine gene expression as a function of the clinical progression of Alzheimer disease dementia.

    James D. Luterman;Vahram Haroutunian;Shrishailam Yemul;Lap Ho

  • Identification of brain-targeted bioactive dietary quercetin-3-O-glucuronide as a novel intervention for Alzheimer's disease

    Lap Ho;Mario G. Ferruzzi;Elsa M. Janle;Jun Wang

  • Identification of potential CSF biomarkers in ALS

    G. M. Pasinetti;L. H. Ungar;D. J. Lange;S. Yemul

  • Brain-Targeted Proanthocyanidin Metabolites for Alzheimer's Disease Treatment

    Jun Wang;Mario G. Ferruzzi;Lap Ho;Lap Ho;Jack Blount

  • Role of intestinal microbiota in the generation of polyphenol-derived phenolic acid mediated attenuation of Alzheimer's disease β-amyloid oligomerization

    Dongjie Wang;Lap Ho;Jeremiah Faith;Kenjiro Ono

  • Dietary composition modulates brain mass and solubilizable Aβ levels in a mouse model of aggressive Alzheimer's amyloid pathology

    Steve Pedrini;Carlos Thomas;Carlos Thomas;Hannah Brautigam;Hannah Brautigam;James Schmeidler

Frequent Co-Authors

Giulio Maria Pasinetti
Giulio Maria Pasinetti Icahn School of Medicine at Mount Sinai
Mario G. Ferruzzi
Mario G. Ferruzzi North Carolina State University
James E. Simon
James E. Simon Rutgers, The State University of New Jersey
Vahram Haroutunian
Vahram Haroutunian Icahn School of Medicine at Mount Sinai
Bing Gong
Bing Gong University at Buffalo, State University of New York
Sam Gandy
Sam Gandy Icahn School of Medicine at Mount Sinai
David B. Teplow
David B. Teplow University of California, Los Angeles
Paul S. Aisen
Paul S. Aisen University of Southern California
Stephen T. Talcott
Stephen T. Talcott Texas A&M University
Patrick R. Hof
Patrick R. Hof Icahn School of Medicine at Mount Sinai

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