World's Best Scientists 2026 revealed!

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Medicine

D-Index
94
Citations
32274
World Ranking
10493
National Ranking
5401

Overview

Giulio Maria Pasinetti is affiliated with the Icahn School of Medicine at Mount Sinai in the United States. Their research intersects multiple disciplines, primarily focusing on medicine, neuroscience, and biochemistry, genetics, and molecular biology. The subfields of their work include molecular biology, neurology, biological psychiatry, physiology, and behavioral neuroscience.

The scientist's main topics of study encompass tryptophan and brain disorders, neuroinflammation and neurodegeneration mechanisms, gut microbiota and health, Alzheimer's disease research and treatments, stress responses and cortisol, inflammasome and immune disorders, and diet and metabolism studies.

Key recent publications include:

  • "Potential Novel Role of COVID-19 in Alzheimer's Disease and Preventative Mitigation Strategies" (2020) published in Journal of Alzheimer s Disease
  • "Microbiota metabolites modulate the T helper 17 to regulatory T cell (Th17/Treg) imbalance promoting resilience to stress-induced anxiety- and depressive-like behaviors" (2020) in Brain Behavior and Immunity
  • "Chronic Stress-Induced Depression and Anxiety Priming Modulated by Gut-Brain-Axis Immunity" (2021) in Frontiers in Immunology
  • "Recent Advances in Research on Polyphenols: Effects on Microbiota, Metabolism, and Health" (2021) in Molecular Nutrition & Food Research
  • "The NLRP3 Inflammasome as a Critical Actor in the Inflammaging Process" (2020) in Cells

Frequent publication venues for the scientist include:

  • Current Developments in Nutrition (14 publications)
  • Alzheimer s & Dementia (12 publications)
  • Journal of Alzheimer s Disease (6 publications)
  • Molecular Nutrition & Food Research (5 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (4 publications)

Collaborations have been an integral part of their work. Frequent co-authors include:

  • Kyle J. Trageser (21 joint publications)
  • Eun-Jeong Yang (16 joint publications)
  • Sean X. Naughton (13 joint publications)
  • Urdhva Raval (11 joint publications)
  • Susan Westfall (11 joint publications)

Best Publications

  • Inflammation and Alzheimer's disease.

    H Akiyama;S Barger;S Barnum;B Bradt

  • Diet-induced insulin resistance promotes amyloidosis in a transgenic mouse model of Alzheimer’s disease

    Lap Ho;Weiping Qin;Patrick N. Pompl;Zhongmin Xiang

  • Neuronal SIRT1 Activation as a Novel Mechanism Underlying the Prevention of Alzheimer Disease Amyloid Neuropathology by Calorie Restriction

    Weiping Qin;Tianle Yang;Lap Ho;Lap Ho;Zhong Zhao

  • Cyclooxygenase-2 expression is increased in frontal cortex of Alzheimer's disease brain

    G.M Pasinetti;P.S Aisen

  • Clusterin (apoJ) alters the aggregation of amyloid β-peptide (Aβ1-42) and forms slowly sedimenting Aβ complexes that cause oxidative stress

    Oda T;Wals P;Osterburg Hh;Johnson Sa

  • Grape-derived polyphenolics prevent Abeta oligomerization and attenuate cognitive deterioration in a mouse model of Alzheimer's disease.

    Jun Wang;Lap Ho;Wei Zhao;Kenjiro Ono

  • Nicotinamide riboside restores cognition through an upregulation of proliferator-activated receptor-γ coactivator 1α regulated β-secretase 1 degradation and mitochondrial gene expression in Alzheimer's mouse models

    Bing Gong;Yong Pan;Prashant Vempati;Wei Zhao

  • PGC-1α Expression Decreases in the Alzheimer Disease Brain as a Function of Dementia

    Weiping Qin;Vahram Haroutunian;Pavel Katsel;Christopher P. Cardozo

  • Moderate consumption of Cabernet Sauvignon attenuates Abeta neuropathology in a mouse model of Alzheimer's disease.

    Jun Wang;Lap Ho;Zhong Zhao;Ilana Seror

  • Valsartan lowers brain β-amyloid protein levels and improves spatial learning in a mouse model of Alzheimer disease

    Jun Wang;Lap Ho;Linghong Chen;Zhong Zhao

  • Caloric restriction attenuates β-amyloid neuropathology in a mouse model of Alzheimer’s disease

    Jun Wang;Lap Ho;Weiping Qin;Anne B. Rocher

  • Flavonoids and Isoflavonoids: From Plant Biology to Agriculture and Neuroscience

    Richard A. Dixon;Giulio M. Pasinetti

  • A ketogenic diet as a potential novel therapeutic intervention in amyotrophic lateral sclerosis

    Zhong Zhao;Dale J Lange;Andrei Voustianiouk;Donal MacGrogan

  • Protective roles of intestinal microbiota derived short chain fatty acids in Alzheimer’s disease-type beta-amyloid neuropathological mechanisms

    Lap Ho;Kenjiro Ono;Mayumi Tsuji;Paolo Mazzola

  • Bioavailability of Gallic Acid and Catechins from Grape Seed Polyphenol Extract is Improved by Repeated Dosing in Rats: Implications for Treatment in Alzheimer's Disease

    Mario G. Ferruzzi;Jessica K. Lobo;Elsa M. Janle;Bruce Cooper

  • REGIONAL DISTRIBUTION OF CYCLOOXYGENASE-2 IN THE HIPPOCAMPAL FORMATION IN ALZHEIMER'S DISEASE

    Lap Ho;Cristiana Pieroni;David Winger;Dushyant P. Purohit

  • Association of apolipoprotein E genotype with brain levels of apolipoprotein E and apolipoprotein J (clusterin) in Alzheimer disease

    Philippe Bertrand;Judes Poirier;Tomiichiro Oda;Caleb E. Finch

  • Potentiation of excitotoxicity in transgenic mice overexpressing neuronal cyclooxygenase-2.

    Kevin A. Kelley;Lap Ho;David Winger;Jose Freire-Moar

  • Roles of Resveratrol and Other Grape-Derived Polyphenols in Alzheimer’s Disease Prevention and Treatment

    Giulio Maria Pasinetti;Jun Wang;Lap Ho;Lap Ho;Wei Zhao;Wei Zhao

  • Dietary composition modulates brain mass and solubilizable Aβ levels in a mouse model of aggressive Alzheimer's amyloid pathology

    Steve Pedrini;Carlos Thomas;Carlos Thomas;Hannah Brautigam;Hannah Brautigam;James Schmeidler

Frequent Co-Authors

Lap Ho
Lap Ho Icahn School of Medicine at Mount Sinai
Caleb E. Finch
Caleb E. Finch University of Southern California
Paul S. Aisen
Paul S. Aisen University of Southern California
Mario G. Ferruzzi
Mario G. Ferruzzi North Carolina State University
James E. Simon
James E. Simon Rutgers, The State University of New Jersey
Bing Gong
Bing Gong University at Buffalo, State University of New York
Vahram Haroutunian
Vahram Haroutunian Icahn School of Medicine at Mount Sinai
Stefano Govoni
Stefano Govoni University of Pavia
Weiping Qin
Weiping Qin Jilin University
Richard A. Dixon
Richard A. Dixon University of North Texas

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