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D-Index & Metrics

Neuroscience

D-Index
90
Citations
31660
World Ranking
1105
National Ranking
573

Medicine

D-Index
90
Citations
31660
World Ranking
12160
National Ranking
6237

Overview

Douglas G. Walker is affiliated with Arizona State University in the United States. Their research spans various fields within medicine and biochemistry, genetics, and molecular biology, with a notable focus on neurology, physiology, molecular biology, and rheumatology.

The main topics addressed in Walker's work include:

  • Alzheimer's disease research and treatments
  • Neuroinflammation and neurodegeneration mechanisms
  • Redox biology and oxidative stress
  • Neurological disease mechanisms and treatments
  • Endoplasmic reticulum stress and disease
  • Health, environment, cognitive aging
  • Nutritional studies and diet

Walker's recent published papers reflect these research interests. Notable publications include:

  • "Patterns of Expression of Purinergic Receptor P2RY12, a Putative Marker for Non-Activated Microglia, in Aged and Alzheimer's Disease Brains," 2020, International Journal of Molecular Sciences
  • "Defining activation states of microglia in human brain tissue: an unresolved issue for Alzheimer's disease," 2020, Neuroimmunology and Neuroinflammation
  • "Thioredoxin-Interacting Protein (TXNIP) with Focus on Brain and Neurodegenerative Diseases," 2020, International Journal of Molecular Sciences
  • "Characterization of a Conformation-Restricted Amyloid β Peptide and Immunoreactivity of Its Antibody in Human AD brain," 2021, ACS Chemical Neuroscience
  • "High-Resolution Mass Spectrometry for Human Exposomics: Expanding Chemical Space Coverage," 2024, Environmental Science & Technology

Publication venues that frequently feature Walker's work include:

  • International Journal of Molecular Sciences
  • Lara D. Veeken
  • Environmental Science & Technology
  • Neuroimmunology and Neuroinflammation
  • Neuroscience Letters

Walker has collaborated regularly with several coauthors, including:

  • Ikuo Tooyama
  • Thomas G. Beach
  • Geidy E. Serrano
  • Anarmaa Mendsaikhan
  • Lucia I. Sue

The scientist's work spans multiple subfields and contributes to ongoing research in understanding complex neurodegenerative diseases such as Alzheimer's disease, the molecular mechanisms underlying neuroinflammation, and biological stress responses.

Best Publications

  • Inflammation and Alzheimer's disease.

    H Akiyama;S Barger;S Barnum;B Bradt

  • ABAD Directly Links Aß to Mitochondrial Toxicity in Alzheimer's Disease

    Joyce W. Lustbader;Maurizio Cirilli;Chang Lin;Hong Wei Xu;Hong Wei Xu

  • Multi-organ distribution of phosphorylated α-synuclein histopathology in subjects with Lewy body disorders

    Thomas G. Beach;Charles H. Adler;Lucia I. Sue;Linda Vedders

  • Microglia in degenerative neurological disease

    Patrick L. McGeer;Toshio Kawamata;Douglas G. Walker;Haruhiko Akiyama

  • A high-density whole-genome association study reveals that APOE is the major susceptibility gene for sporadic late-onset Alzheimer's disease

    Keith D. Coon;Amanda J. Myers;David W. Craig;Jennifer A. Webster

  • Unified Staging System for Lewy Body Disorders: Correlation with Nigrostriatal Degeneration, Cognitive Impairment and Motor Dysfunction

    Thomas G. Beach;Charles H. Adler;LihFen F. Lue;Lucia I. Sue

  • Inflammation and Alzheimer's disease pathogenesis.

    Joseph Rogers;Joseph Rogers;Scott Webster;Scott Webster;Lih-Fen Lue;Lih-Fen Lue;Libuse Brachova;Libuse Brachova

  • Immune phenotypes of microglia in human neurodegenerative disease: challenges to detecting microglial polarization in human brains.

    Douglas G. Walker;Lih-Fen Lue

  • Involvement of microglial receptor for advanced glycation endproducts (RAGE) in Alzheimer's disease: identification of a cellular activation mechanism.

    Lih-Fen Lue;Douglas G. Walker;Libuse Brachova;Thomas G. Beach

  • Inflammatory repertoire of Alzheimer's disease and nondemented elderly microglia in vitro.

    Lih Fen Lue;Russell Rydel;Elizabeth F. Brigham;Li Bang Yang

  • Arizona Study of Aging and Neurodegenerative Disorders and Brain and Body Donation Program

    Thomas G. Beach;Charles H. Adler;Lucia I. Sue;Geidy Serrano

  • RAGE potentiates Aβ-induced perturbation of neuronal function in transgenic mice

    Ottavio Arancio;Hui Ping Zhang;Xi Chen;Chang Lin

  • RAGE-dependent signaling in microglia contributes to neuroinflammation, Aβ accumulation, and impaired learning/memory in a mouse model of Alzheimer’s disease

    Fang Fang;Lih-Fen Lue;Shiqiang Yan;Hongwei Xu;Hongwei Xu

  • Molecular and Cellular Characterization of the Membrane Attack Complex, C5b-9, in Alzheimer’s Disease

    S Webster;L.-F Lue;L Brachova;A.J Tenner

  • Decreased expression of CD200 and CD200 receptor in Alzheimer's disease: A potential mechanism leading to chronic inflammation

    Douglas G. Walker;Jessica E. Dalsing-Hernandez;Nicole A. Campbell;Lih-Fen Lue

  • Gene expression profiles in anatomically and functionally distinct regions of the normal aged human brain

    Winnie S. Liang;Travis Dunckley;Thomas G. Beach;Andrew Grover

  • The Sun Health Research Institute Brain Donation Program: description and experience, 1987-2007.

    Thomas G. Beach;Lucia I. Sue;Douglas G. Walker;Alex E. Roher

  • Complement and cytokine gene expression in cultured microglial derived from postmortem human brains.

    D. G. Walker;S. U. Kim;P. L. McGeer

  • Upregulated Expression of Purinergic P2X7 Receptor in Alzheimer Disease and Amyloid-β Peptide-Treated Microglia and in Peptide-Injected Rat Hippocampus

    James G. McLarnon;Jae K. Ryu;Douglas G. Walker;Hyun B. Choi

  • Increased Aβ Peptides and Reduced Cholesterol and Myelin Proteins Characterize White Matter Degeneration in Alzheimer's Disease†

    Alex E. Roher;Nicole Weiss;Tyler A. Kokjohn;Yu Min Kuo

Frequent Co-Authors

Thomas G. Beach
Thomas G. Beach Banner Health
Marwan N. Sabbagh
Marwan N. Sabbagh Lou Ruvo Brain Institute
Charles H. Adler
Charles H. Adler Mayo Clinic
Patrick L. McGeer
Patrick L. McGeer University of British Columbia
Alex E. Roher
Alex E. Roher Banner Health
John N. Caviness
John N. Caviness Mayo Clinic
Holly A. Shill
Holly A. Shill Barrow Neurological Institute
Ikuo Tooyama
Ikuo Tooyama Shiga University of Medical Science
Edith G. McGeer
Edith G. McGeer University of British Columbia
Eric M. Reiman
Eric M. Reiman Arizona State University

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