World's Best Scientists 2026 revealed!

D-Index & Metrics

Neuroscience

D-Index
58
Citations
11799
World Ranking
4173
National Ranking
120

Ikuo Tooyama publication distribution in Neuroscience in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Neuroscience in 2026. The highlighted bar marks where Ikuo Tooyama sits on this spectrum.

38–47 publications: 18 scientists 48–57 publications: 79 scientists 58–67 publications: 193 scientists 68–77 publications: 323 scientists 78–87 publications: 406 scientists 88–97 publications: 452 scientists 98–107 publications: 539 scientists 108–117 publications: 505 scientists 118–127 publications: 522 scientists 128–137 publications: 469 scientists 138–147 publications: 456 scientists 148–157 publications: 459 scientists 158–167 publications: 397 scientists 168–177 publications: 383 scientists 178–187 publications: 350 scientists 188–197 publications: 302 scientists 198–207 publications: 306 scientists 208–217 publications: 262 scientists 218–227 publications: 242 scientists 228–237 publications: 220 scientists 238–247 publications: 203 scientists 248–257 publications: 174 scientists 258–267 publications: 176 scientists 268–277 publications: 175 scientists 278–287 publications: 125 scientists 288–297 publications: 116 scientists 298–307 publications: 127 scientists 308–317 publications: 128 scientists 318–327 publications: 99 scientists 328–337 publications: 89 scientists 338–347 publications: 78 scientists 348–357 publications: 96 scientists 358–367 publications: 66 scientists 368–377 publications: 59 scientists 378–387 publications: 65 scientists 388–397 publications: 54 scientists 398–407 publications: 48 scientists 408–417 publications: 49 scientists 418–427 publications: 34 scientists 428–437 publications: 31 scientists 438–447 publications: 30 scientists 448–457 publications: 31 scientists 458–467 publications: 36 scientists 468–477 publications: 40 scientists 478–487 publications: 35 scientists 488–497 publications: 30 scientists 498–507 publications: 23 scientists 508–517 publications: 26 scientists 518–527 publications: 20 scientists 528–537 publications: 23 scientists 538–547 publications: 20 scientists 548–557 publications: 20 scientists 558–567 publications: 17 scientists 568–577 publications: 14 scientists 578–587 publications: 20 scientists 588–597 publications: 20 scientists 598–607 publications: 19 scientists 608–617 publications: 18 scientists 618–627 publications: 17 scientists 628–637 publications: 11 scientists 638–647 publications: 11 scientists 648–657 publications: 11 scientists 658–667 publications: 8 scientists 668–677 publications: 7 scientists 678–687 publications: 11 scientists 688–697 publications: 10 scientists 698–707 publications: 4 scientists 708–717 publications: 6 scientists 718–727 publications: 5 scientists 728–737 publications: 5 scientists 738–747 publications: 9 scientists 748–757 publications: 9 scientists 758–767 publications: 3 scientists 768–777 publications: 7 scientists 778–787 publications: 7 scientists 788–797 publications: 6 scientists 798–807 publications: 2 scientists 808–817 publications: 2 scientists 818–827 publications: 7 scientists 828–837 publications: 0 scientists 838–847 publications: 9 scientists 848–857 publications: 3 scientists 858–867 publications: 1 scientists 868–877 publications: 3 scientists 878–886 publications: 6 scientists 887+ publications: 100 scientists
38 publications 887+

This scientist: 409 publications — 91st percentile

91% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 887 publications or more.

Ikuo Tooyama D-index placement in Neuroscience in 2026

The chart shows the D-index (discipline H-index) distribution of Neuroscience scientists ranked by Research.com in 2026. The highlighted bar marks where Ikuo Tooyama sits on this spectrum.

30–31 D-Index: 42 scientists 32–33 D-Index: 172 scientists 34–35 D-Index: 296 scientists 36–37 D-Index: 435 scientists 38–39 D-Index: 459 scientists 40–41 D-Index: 456 scientists 42–43 D-Index: 467 scientists 44–45 D-Index: 478 scientists 46–47 D-Index: 512 scientists 48–49 D-Index: 435 scientists 50–51 D-Index: 425 scientists 52–53 D-Index: 418 scientists 54–55 D-Index: 392 scientists 56–57 D-Index: 357 scientists 58–59 D-Index: 334 scientists 60–61 D-Index: 328 scientists 62–63 D-Index: 260 scientists 64–65 D-Index: 278 scientists 66–67 D-Index: 239 scientists 68–69 D-Index: 250 scientists 70–71 D-Index: 210 scientists 72–73 D-Index: 200 scientists 74–75 D-Index: 189 scientists 76–77 D-Index: 170 scientists 78–79 D-Index: 146 scientists 80–81 D-Index: 113 scientists 82–83 D-Index: 126 scientists 84–85 D-Index: 100 scientists 86–87 D-Index: 84 scientists 88–89 D-Index: 99 scientists 90–91 D-Index: 84 scientists 92–93 D-Index: 85 scientists 94–95 D-Index: 72 scientists 96–97 D-Index: 76 scientists 98–99 D-Index: 45 scientists 100–101 D-Index: 49 scientists 102–103 D-Index: 43 scientists 104–105 D-Index: 32 scientists 106–107 D-Index: 45 scientists 108–109 D-Index: 50 scientists 110–111 D-Index: 32 scientists 112–113 D-Index: 39 scientists 114–115 D-Index: 32 scientists 116–117 D-Index: 29 scientists 118–119 D-Index: 27 scientists 120–121 D-Index: 19 scientists 122–123 D-Index: 23 scientists 124–125 D-Index: 27 scientists 126–127 D-Index: 16 scientists 128–129 D-Index: 24 scientists 130–131 D-Index: 13 scientists 132–133 D-Index: 21 scientists 134–135 D-Index: 17 scientists 136–137 D-Index: 14 scientists 138–139 D-Index: 15 scientists 140–141 D-Index: 10 scientists 142–143 D-Index: 10 scientists 144–145 D-Index: 13 scientists 146–147 D-Index: 9 scientists 148–149 D-Index: 8 scientists 150–151 D-Index: 6 scientists 152–153 D-Index: 6 scientists 154–155 D-Index: 7 scientists 156–157 D-Index: 7 scientists 158–159 D-Index: 10 scientists 160–161 D-Index: 4 scientists 162 D-Index: 8 scientists 163+ D-Index: 100 scientists
30 D-Index 163+

This scientist: 58 D-Index — 57th percentile

57% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 163 D-Index or more.

Overview

Ikuo Tooyama is affiliated with Shiga University of Medical Science in Japan. Their research spans multiple fields, with a primary focus on medicine and biochemistry, genetics, and molecular biology. Within these broad areas, Tooyama has contributed notably to physiology, molecular biology, and neurology, while also engaging in studies related to nutrition and dietetics and cell biology.

Tooyama's work addresses several main topics including Alzheimer's disease research and treatments, neuroinflammation and neurodegeneration mechanisms, redox biology and oxidative stress, drug transport and resistance mechanisms, prion diseases and protein misfolding, Parkinson's disease mechanisms and treatments, and endoplasmic reticulum stress and disease.

Frequent publication venues for Tooyama include the International Journal of Molecular Sciences and ACTA HISTOCHEMICA ET CYTOCHEMICA, each hosting five of their papers. Additional journals where Tooyama has published multiple times include Molecules, ACS Chemical Neuroscience, and Biochemical and Biophysical Research Communications.

Notable recent papers authored or co-authored by Tooyama feature titles such as:

  • Thioredoxin-Interacting Protein (TXNIP) with Focus on Brain and Neurodegenerative Diseases, 2020, International Journal of Molecular Sciences
  • Patterns of Expression of Purinergic Receptor P2RY12, a Putative Marker for Non-Activated Microglia, in Aged and Alzheimer's Disease Brains, 2020, International Journal of Molecular Sciences
  • An insight into the neuroprotective and anti-neuroinflammatory effects and mechanisms of Moringa oleifera, 2023, Frontiers in Pharmacology
  • A Mechanistic Evaluation of Antioxidant Nutraceuticals on Their Potential against Age-Associated Neurodegenerative Diseases, 2020, Antioxidants
  • Generation of Transgenic Cynomolgus Monkeys Overexpressing the Gene for Amyloid-β Precursor Protein, 2020, Journal of Alzheimer s Disease

Tooyama has collaborated frequently with colleagues in their field. Among the most common co-authors are Daijiro Yanagisawa, with 28 joint works; Zulzikry Hafiz Abu Bakar, with 10; Tomoko Kato, with 9; Douglas G. Walker, with 8; and Aya Kadota, also with 8 joint publications.

Best Publications

  • Microglia in degenerative neurological disease

    Patrick L. McGeer;Toshio Kawamata;Douglas G. Walker;Haruhiko Akiyama

  • Human positron emission tomographic [18F]Fluorodopa studies correlate with dopamine cell counts and levels

    B. J. Snow;I. Tooyama;I. Tooyama;E. G. McGeer;T. Yamada

  • Reduced Neuron-Specific Expression of the TAF1 Gene Is Associated with X-Linked Dystonia-Parkinsonism

    Satoshi Makino;Satoshi Makino;Ryuji Kaji;Satoshi Ando;Satoshi Ando;Maiko Tomizawa

  • Enhancement of progenitor cell division in the dentate gyrus triggered by initial limbic seizures in rat models of epilepsy.

    Eiji Nakagawa;Yoshinari Aimi;Osamu Yasuhara;Ikuo Tooyama

  • Reactive microglia express class I and class II major histocompatibility complex antigens in Alzheimer's disease

    I. Tooyama;H. Kimura;H. Akiyama;P.L. McGeer

  • Lactotransferrin immunocytochemistry in Alzheimer and normal human brain.

    T Kawamata;I Tooyama;T Yamada;D G Walker

  • Loss of insulin receptor immunoreactivity from the substantia nigra pars compacta neurons in Parkinson's disease.

    I. Moroo;T. Yamada;H. Makino;I. Tooyama

  • Expression of intercellular adhesion molecule (ICAM)-1 by a subset of astrocytes in Alzheimer disease and some other degenerative neurological disorders

    Haruhiko Akiyama;Toshio Kawamata;Tatsuo Yamada;Ikuo Tooyama

  • Functional anatomy of the basal ganglia in X-linked recessive dystonia-parkinsonism

    Satoshi Goto;Lillian V. Lee;Edwin L. Munoz;Ikuo Tooyama

  • Relationship between the tautomeric structures of curcumin derivatives and their Aβ-binding activities in the context of therapies for Alzheimer's disease.

    Daijiro Yanagisawa;Nobuaki Shirai;Tomone Amatsubo;Hiroyasu Taguchi

  • Insulin receptor mRNA in the substantia nigra in Parkinson's disease

    Mitsuo Takahashi;Tatsuo Yamada;Ikuo Tooyama;Iku Moroo

  • Loss of basic fibroblast growth factor in substantia nigra neurons in Parkinson's disease

    I. Tooyama;T. Kawamata;D. Walker;T. Yamada

  • Early response of brain resident microglia to kainic acid-induced hippocampal lesions

    Haruhiko Akiyama;Ikuo Tooyama;Hiromi Kondo;Kenji Ikeda

  • Human neural stem cells over-expressing choline acetyltransferase restore cognition in rat model of cognitive dysfunction.

    Dongsun Park;Hong Jun Lee;Hong Jun Lee;Seong Soo Joo;Dae-Kwon Bae

  • Morphological diversities of CD44 positive astrocytes in the cerebral cortex of normal subjects and patients with Alzheimer's disease

    Haruhiko Akiyama;Ikuo Tooyama;Toshio Kawamata;Kenji Ikeda

  • A protein encoded by an alternative splice variant of choline acetyltransferase mRNA is localized preferentially in peripheral nerve cells and fibers.

    Ikuo Tooyama;Hiroshi Kimura

  • Microglial transplantation increases amyloid-β clearance in Alzheimer model rats

    Kazuyuki Takata;Yoshihisa Kitamura;Daijiro Yanagisawa;Shigehiro Morikawa

  • DJ-1 Protects against Neurodegeneration Caused by Focal Cerebral Ischemia and Reperfusion in Rats

    Daijiro Yanagisawa;Yoshihisa Kitamura;Masatoshi Inden;Kazuyuki Takata

  • Hydrogen peroxide-induced apoptosis mediated by p53 protein in glial cells

    Yoshihisa Kitamura;Takashi Ota;Yasuji Matsuoka;Ikuo Tooyama

  • Synergistic effect between proteasome and autophagosome in the clearance of polyubiquitinated TDP-43.

    Makoto Urushitani;Takashi Sato;Takashi Sato;Hitoshi Bamba;Yasuo Hisa

  • Thioredoxin-Interacting Protein (TXNIP) with Focus on Brain and Neurodegenerative Diseases.

    Haruka Tsubaki;Ikuo Tooyama;Douglas Gordon Walker

Frequent Co-Authors

Hiroshi Kimura
Hiroshi Kimura Tokyo Institute of Technology
Yutaka Oomura
Yutaka Oomura Kyushu University
Patrick L. McGeer
Patrick L. McGeer University of British Columbia
Kazuo Sasaki
Kazuo Sasaki University of Toyama
Douglas G. Walker
Douglas G. Walker Arizona State University
Shun Shimohama
Shun Shimohama Sapporo Medical University
Edith G. McGeer
Edith G. McGeer University of British Columbia
Masaki Mori
Masaki Mori Kyushu University
Katsuyuki Miura
Katsuyuki Miura Shiga University of Medical Science
Yasuyuki Nomura
Yasuyuki Nomura Kurume University

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Finally, advancing your expertise with an online masters psychology degree can open doors to diverse, high-impact career pathways. These programs equip students with the research and clinical skills necessary for a variety of roles in healthcare, education, and beyond.

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