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Ikuo Tooyama

D-Index & Metrics

Discipline name D-Index World Ranking Current World Ranking National Ranking Current National Ranking Publications Citations
Neuroscience 58 4173 3827 120 115 409 11799

Ikuo Tooyama publications per year

The chart shows the history of publications by Ikuo Tooyama between 1989 and 2025, highlighting the no. of papers published in each year and offering an overview of the publication velocity of this scholar. Ikuo Tooyama published across 37 years, from 1989 to 2025, averaging 11.4 papers a year. Output peaked at 21 publications in 1994. 13 of the 420 publications appeared in the last two years.

No. of publications
5 10 15 20
Bar chart. Horizontal axis: year, 1989 to 2025. Vertical axis: number of publications, 0 to 21. Peak 21 publications in 1994. 1989: 1 publication 1990: 8 publications 1991: 12 publications 1992: 7 publications 1993: 17 publications 1994: 21 publications 1995: 13 publications 1996: 14 publications 1997: 13 publications 1998: 12 publications 1999: 12 publications 2000: 7 publications 2001: 8 publications 2002: 2 publications 2003: 6 publications 2004: 7 publications 2005: 9 publications 2006: 10 publications 2007: 9 publications 2008: 10 publications 2009: 15 publications 2010: 12 publications 2011: 19 publications 2012: 20 publications 2013: 16 publications 2014: 11 publications 2015: 10 publications 2016: 15 publications 2017: 13 publications 2018: 16 publications 2019: 12 publications 2020: 16 publications 2021: 16 publications 2022: 8 publications 2023: 10 publications 2024: 8 publications 2025: 5 publications
1989 2025

420 publications in total across all disciplines

View publications per year as a table
Ikuo Tooyama: publications per year, 1989 to 2025
Year Publications
1989 1
1990 8
1991 12
1992 7
1993 17
1994 21
1995 13
1996 14
1997 13
1998 12
1999 12
2000 7
2001 8
2002 2
2003 6
2004 7
2005 9
2006 10
2007 9
2008 10
2009 15
2010 12
2011 19
2012 20
2013 16
2014 11
2015 10
2016 15
2017 13
2018 16
2019 12
2020 16
2021 16
2022 8
2023 10
2024 8
2025 5
Total 420
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Ikuo Tooyama publication distribution in Neuroscience in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Neuroscience in 2026. The highlighted bar marks where Ikuo Tooyama sits on this spectrum.

No. of scientists
100 200 300 400 500
Bar chart with 86 bars. Horizontal axis: publications, 38–47 to 887+. Vertical axis: number of scientists, 0 to 539. Most scientists, 539, have 98–107 publications. The last bar groups every scientist with 887 publications or more. The highlighted bar, 408–417 publications, is where this scientist sits. 38–47 publications: 18 scientists 48–57 publications: 79 scientists 58–67 publications: 193 scientists 68–77 publications: 323 scientists 78–87 publications: 406 scientists 88–97 publications: 452 scientists 98–107 publications: 539 scientists 108–117 publications: 505 scientists 118–127 publications: 522 scientists 128–137 publications: 469 scientists 138–147 publications: 456 scientists 148–157 publications: 459 scientists 158–167 publications: 397 scientists 168–177 publications: 383 scientists 178–187 publications: 350 scientists 188–197 publications: 302 scientists 198–207 publications: 306 scientists 208–217 publications: 262 scientists 218–227 publications: 242 scientists 228–237 publications: 220 scientists 238–247 publications: 203 scientists 248–257 publications: 174 scientists 258–267 publications: 176 scientists 268–277 publications: 175 scientists 278–287 publications: 125 scientists 288–297 publications: 116 scientists 298–307 publications: 127 scientists 308–317 publications: 128 scientists 318–327 publications: 99 scientists 328–337 publications: 89 scientists 338–347 publications: 78 scientists 348–357 publications: 96 scientists 358–367 publications: 66 scientists 368–377 publications: 59 scientists 378–387 publications: 65 scientists 388–397 publications: 54 scientists 398–407 publications: 48 scientists 408–417 publications: 49 scientists 418–427 publications: 34 scientists 428–437 publications: 31 scientists 438–447 publications: 30 scientists 448–457 publications: 31 scientists 458–467 publications: 36 scientists 468–477 publications: 40 scientists 478–487 publications: 35 scientists 488–497 publications: 30 scientists 498–507 publications: 23 scientists 508–517 publications: 26 scientists 518–527 publications: 20 scientists 528–537 publications: 23 scientists 538–547 publications: 20 scientists 548–557 publications: 20 scientists 558–567 publications: 17 scientists 568–577 publications: 14 scientists 578–587 publications: 20 scientists 588–597 publications: 20 scientists 598–607 publications: 19 scientists 608–617 publications: 18 scientists 618–627 publications: 17 scientists 628–637 publications: 11 scientists 638–647 publications: 11 scientists 648–657 publications: 11 scientists 658–667 publications: 8 scientists 668–677 publications: 7 scientists 678–687 publications: 11 scientists 688–697 publications: 10 scientists 698–707 publications: 4 scientists 708–717 publications: 6 scientists 718–727 publications: 5 scientists 728–737 publications: 5 scientists 738–747 publications: 9 scientists 748–757 publications: 9 scientists 758–767 publications: 3 scientists 768–777 publications: 7 scientists 778–787 publications: 7 scientists 788–797 publications: 6 scientists 798–807 publications: 2 scientists 808–817 publications: 2 scientists 818–827 publications: 7 scientists 828–837 publications: 0 scientists 838–847 publications: 9 scientists 848–857 publications: 3 scientists 858–867 publications: 1 scientist 868–877 publications: 3 scientists 878–886 publications: 6 scientists 887+ publications: 100 scientists
38–47 publications 887+

This scientist: 409 publications — 91st percentile

91% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 887 publications or more.

View publications distribution as a table
Number of Neuroscience scientists by publication count, Research.com 2026 ranking edition. Based on 9,597 ranked scientists.
Publications Scientists This scientist
38–47 18
48–57 79
58–67 193
68–77 323
78–87 406
88–97 452
98–107 539
108–117 505
118–127 522
128–137 469
138–147 456
148–157 459
158–167 397
168–177 383
178–187 350
188–197 302
198–207 306
208–217 262
218–227 242
228–237 220
238–247 203
248–257 174
258–267 176
268–277 175
278–287 125
288–297 116
298–307 127
308–317 128
318–327 99
328–337 89
338–347 78
348–357 96
358–367 66
368–377 59
378–387 65
388–397 54
398–407 48
408–417 49 409
418–427 34
428–437 31
438–447 30
448–457 31
458–467 36
468–477 40
478–487 35
488–497 30
498–507 23
508–517 26
518–527 20
528–537 23
538–547 20
548–557 20
558–567 17
568–577 14
578–587 20
588–597 20
598–607 19
608–617 18
618–627 17
628–637 11
638–647 11
648–657 11
658–667 8
668–677 7
678–687 11
688–697 10
698–707 4
708–717 6
718–727 5
728–737 5
738–747 9
748–757 9
758–767 3
768–777 7
778–787 7
788–797 6
798–807 2
808–817 2
818–827 7
828–837 0
838–847 9
848–857 3
858–867 1
868–877 3
878–886 6
887+ 100
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Ikuo Tooyama D-index placement in Neuroscience in 2026

The chart shows the D-index (discipline H-index) distribution of Neuroscience scientists ranked by Research.com in 2026. The highlighted bar marks where Ikuo Tooyama sits on this spectrum.

No. of scientists
100 200 300 400 500
Bar chart with 68 bars. Horizontal axis: D-Index, 30–31 to 163+. Vertical axis: number of scientists, 0 to 512. Most scientists, 512, have 46–47 D-Index. The last bar groups every scientist with 163 D-Index or more. The highlighted bar, 58–59 D-Index, is where this scientist sits. 30–31 D-Index: 42 scientists 32–33 D-Index: 172 scientists 34–35 D-Index: 296 scientists 36–37 D-Index: 435 scientists 38–39 D-Index: 459 scientists 40–41 D-Index: 456 scientists 42–43 D-Index: 467 scientists 44–45 D-Index: 478 scientists 46–47 D-Index: 512 scientists 48–49 D-Index: 435 scientists 50–51 D-Index: 425 scientists 52–53 D-Index: 418 scientists 54–55 D-Index: 392 scientists 56–57 D-Index: 357 scientists 58–59 D-Index: 334 scientists 60–61 D-Index: 328 scientists 62–63 D-Index: 260 scientists 64–65 D-Index: 278 scientists 66–67 D-Index: 239 scientists 68–69 D-Index: 250 scientists 70–71 D-Index: 210 scientists 72–73 D-Index: 200 scientists 74–75 D-Index: 189 scientists 76–77 D-Index: 170 scientists 78–79 D-Index: 146 scientists 80–81 D-Index: 113 scientists 82–83 D-Index: 126 scientists 84–85 D-Index: 100 scientists 86–87 D-Index: 84 scientists 88–89 D-Index: 99 scientists 90–91 D-Index: 84 scientists 92–93 D-Index: 85 scientists 94–95 D-Index: 72 scientists 96–97 D-Index: 76 scientists 98–99 D-Index: 45 scientists 100–101 D-Index: 49 scientists 102–103 D-Index: 43 scientists 104–105 D-Index: 32 scientists 106–107 D-Index: 45 scientists 108–109 D-Index: 50 scientists 110–111 D-Index: 32 scientists 112–113 D-Index: 39 scientists 114–115 D-Index: 32 scientists 116–117 D-Index: 29 scientists 118–119 D-Index: 27 scientists 120–121 D-Index: 19 scientists 122–123 D-Index: 23 scientists 124–125 D-Index: 27 scientists 126–127 D-Index: 16 scientists 128–129 D-Index: 24 scientists 130–131 D-Index: 13 scientists 132–133 D-Index: 21 scientists 134–135 D-Index: 17 scientists 136–137 D-Index: 14 scientists 138–139 D-Index: 15 scientists 140–141 D-Index: 10 scientists 142–143 D-Index: 10 scientists 144–145 D-Index: 13 scientists 146–147 D-Index: 9 scientists 148–149 D-Index: 8 scientists 150–151 D-Index: 6 scientists 152–153 D-Index: 6 scientists 154–155 D-Index: 7 scientists 156–157 D-Index: 7 scientists 158–159 D-Index: 10 scientists 160–161 D-Index: 4 scientists 162 D-Index: 8 scientists 163+ D-Index: 100 scientists
30–31 D-Index 163+

This scientist: 58 D-Index — 57th percentile

57% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 163 D-Index or more.

View D-Index distribution as a table
Number of Neuroscience scientists by D-index, Research.com 2026 ranking edition. Based on 9,597 ranked scientists.
D-Index Scientists This scientist
30–31 42
32–33 172
34–35 296
36–37 435
38–39 459
40–41 456
42–43 467
44–45 478
46–47 512
48–49 435
50–51 425
52–53 418
54–55 392
56–57 357
58–59 334 58
60–61 328
62–63 260
64–65 278
66–67 239
68–69 250
70–71 210
72–73 200
74–75 189
76–77 170
78–79 146
80–81 113
82–83 126
84–85 100
86–87 84
88–89 99
90–91 84
92–93 85
94–95 72
96–97 76
98–99 45
100–101 49
102–103 43
104–105 32
106–107 45
108–109 50
110–111 32
112–113 39
114–115 32
116–117 29
118–119 27
120–121 19
122–123 23
124–125 27
126–127 16
128–129 24
130–131 13
132–133 21
134–135 17
136–137 14
138–139 15
140–141 10
142–143 10
144–145 13
146–147 9
148–149 8
150–151 6
152–153 6
154–155 7
156–157 7
158–159 10
160–161 4
162 8
163+ 100
Download as CSV

Overview

Ikuo Tooyama is affiliated with Shiga University of Medical Science in Japan. Their research spans multiple fields, with a primary focus on medicine and biochemistry, genetics, and molecular biology. Within these broad areas, Tooyama has contributed notably to physiology, molecular biology, and neurology, while also engaging in studies related to nutrition and dietetics and cell biology.

Tooyama's work addresses several main topics including Alzheimer's disease research and treatments, neuroinflammation and neurodegeneration mechanisms, redox biology and oxidative stress, drug transport and resistance mechanisms, prion diseases and protein misfolding, Parkinson's disease mechanisms and treatments, and endoplasmic reticulum stress and disease.

Frequent publication venues for Tooyama include the International Journal of Molecular Sciences and ACTA HISTOCHEMICA ET CYTOCHEMICA, each hosting five of their papers. Additional journals where Tooyama has published multiple times include Molecules, ACS Chemical Neuroscience, and Biochemical and Biophysical Research Communications.

Notable recent papers authored or co-authored by Tooyama feature titles such as:

  • Thioredoxin-Interacting Protein (TXNIP) with Focus on Brain and Neurodegenerative Diseases, 2020, International Journal of Molecular Sciences
  • Patterns of Expression of Purinergic Receptor P2RY12, a Putative Marker for Non-Activated Microglia, in Aged and Alzheimer's Disease Brains, 2020, International Journal of Molecular Sciences
  • An insight into the neuroprotective and anti-neuroinflammatory effects and mechanisms of Moringa oleifera, 2023, Frontiers in Pharmacology
  • A Mechanistic Evaluation of Antioxidant Nutraceuticals on Their Potential against Age-Associated Neurodegenerative Diseases, 2020, Antioxidants
  • Generation of Transgenic Cynomolgus Monkeys Overexpressing the Gene for Amyloid-β Precursor Protein, 2020, Journal of Alzheimer s Disease

Tooyama has collaborated frequently with colleagues in their field. Among the most common co-authors are Daijiro Yanagisawa, with 28 joint works; Zulzikry Hafiz Abu Bakar, with 10; Tomoko Kato, with 9; Douglas G. Walker, with 8; and Aya Kadota, also with 8 joint publications.

Best Publications

  • Microglia in degenerative neurological disease

    Patrick L. McGeer;Toshio Kawamata;Douglas G. Walker;Haruhiko Akiyama

  • Human positron emission tomographic [18F]Fluorodopa studies correlate with dopamine cell counts and levels

    B. J. Snow;I. Tooyama;I. Tooyama;E. G. McGeer;T. Yamada

  • Reduced Neuron-Specific Expression of the TAF1 Gene Is Associated with X-Linked Dystonia-Parkinsonism

    Satoshi Makino;Satoshi Makino;Ryuji Kaji;Satoshi Ando;Satoshi Ando;Maiko Tomizawa

  • Enhancement of progenitor cell division in the dentate gyrus triggered by initial limbic seizures in rat models of epilepsy.

    Eiji Nakagawa;Yoshinari Aimi;Osamu Yasuhara;Ikuo Tooyama

  • Reactive microglia express class I and class II major histocompatibility complex antigens in Alzheimer's disease

    I. Tooyama;H. Kimura;H. Akiyama;P.L. McGeer

  • Lactotransferrin immunocytochemistry in Alzheimer and normal human brain.

    T Kawamata;I Tooyama;T Yamada;D G Walker

  • Loss of insulin receptor immunoreactivity from the substantia nigra pars compacta neurons in Parkinson's disease.

    I. Moroo;T. Yamada;H. Makino;I. Tooyama

  • Expression of intercellular adhesion molecule (ICAM)-1 by a subset of astrocytes in Alzheimer disease and some other degenerative neurological disorders

    Haruhiko Akiyama;Toshio Kawamata;Tatsuo Yamada;Ikuo Tooyama

  • Functional anatomy of the basal ganglia in X-linked recessive dystonia-parkinsonism

    Satoshi Goto;Lillian V. Lee;Edwin L. Munoz;Ikuo Tooyama

  • Relationship between the tautomeric structures of curcumin derivatives and their Aβ-binding activities in the context of therapies for Alzheimer's disease.

    Daijiro Yanagisawa;Nobuaki Shirai;Tomone Amatsubo;Hiroyasu Taguchi

  • Insulin receptor mRNA in the substantia nigra in Parkinson's disease

    Mitsuo Takahashi;Tatsuo Yamada;Ikuo Tooyama;Iku Moroo

  • Loss of basic fibroblast growth factor in substantia nigra neurons in Parkinson's disease

    I. Tooyama;T. Kawamata;D. Walker;T. Yamada

  • Early response of brain resident microglia to kainic acid-induced hippocampal lesions

    Haruhiko Akiyama;Ikuo Tooyama;Hiromi Kondo;Kenji Ikeda

  • Human neural stem cells over-expressing choline acetyltransferase restore cognition in rat model of cognitive dysfunction.

    Dongsun Park;Hong Jun Lee;Hong Jun Lee;Seong Soo Joo;Dae-Kwon Bae

  • Morphological diversities of CD44 positive astrocytes in the cerebral cortex of normal subjects and patients with Alzheimer's disease

    Haruhiko Akiyama;Ikuo Tooyama;Toshio Kawamata;Kenji Ikeda

  • A protein encoded by an alternative splice variant of choline acetyltransferase mRNA is localized preferentially in peripheral nerve cells and fibers.

    Ikuo Tooyama;Hiroshi Kimura

  • Microglial transplantation increases amyloid-β clearance in Alzheimer model rats

    Kazuyuki Takata;Yoshihisa Kitamura;Daijiro Yanagisawa;Shigehiro Morikawa

  • DJ-1 Protects against Neurodegeneration Caused by Focal Cerebral Ischemia and Reperfusion in Rats

    Daijiro Yanagisawa;Yoshihisa Kitamura;Masatoshi Inden;Kazuyuki Takata

  • Hydrogen peroxide-induced apoptosis mediated by p53 protein in glial cells

    Yoshihisa Kitamura;Takashi Ota;Yasuji Matsuoka;Ikuo Tooyama

  • Synergistic effect between proteasome and autophagosome in the clearance of polyubiquitinated TDP-43.

    Makoto Urushitani;Takashi Sato;Takashi Sato;Hitoshi Bamba;Yasuo Hisa

  • Thioredoxin-Interacting Protein (TXNIP) with Focus on Brain and Neurodegenerative Diseases.

    Haruka Tsubaki;Ikuo Tooyama;Douglas Gordon Walker

Frequent Co-Authors

Hiroshi Kimura
Hiroshi Kimura Tokyo Institute of Technology
Yutaka Oomura
Yutaka Oomura Kyushu University
Patrick L. McGeer
Patrick L. McGeer University of British Columbia
Kazuo Sasaki
Kazuo Sasaki University of Toyama
Douglas G. Walker
Douglas G. Walker Arizona State University
Shun Shimohama
Shun Shimohama Sapporo Medical University
Edith G. McGeer
Edith G. McGeer University of British Columbia
Masaki Mori
Masaki Mori Kyushu University
Katsuyuki Miura
Katsuyuki Miura Shiga University of Medical Science
Yasuyuki Nomura
Yasuyuki Nomura Kurume University

External Links

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Best Scientists Citing Ikuo Tooyama

Patrick L. McGeer

Patrick L. McGeer

University of British Columbia

Publications: 41

Christine Klein

Christine Klein

University of Lübeck

Publications: 38

David J. Brooks

David J. Brooks

Newcastle University

Publications: 35

Douglas G. Walker

Douglas G. Walker

Arizona State University

Publications: 25

Christian Hölscher

Christian Hölscher

Henan University

Publications: 24

Edith G. McGeer

Edith G. McGeer

University of British Columbia

Publications: 24

Seung U. Kim

Seung U. Kim

University of British Columbia

Publications: 23

Yutaka Oomura

Yutaka Oomura

Kyushu University

Publications: 21

A. Jon Stoessl

A. Jon Stoessl

University of British Columbia

Publications: 21

George Perry

George Perry

The University of Texas at San Antonio

Publications: 18

Laurie J. Ozelius

Laurie J. Ozelius

Harvard University

Publications: 18

Ashok K. Shetty

Ashok K. Shetty

Texas A&M University

Publications: 17

Julie D. Atkin

Julie D. Atkin

Macquarie University

Publications: 15

Ann M. Graybiel

Ann M. Graybiel

MIT

Publications: 15

Michael T. Heneka

Michael T. Heneka

University Hospital Bonn

Publications: 15

John Q. Trojanowski

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Publications: 15

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