World's Best Scientists 2026 revealed!
Ann M. Graybiel

Ann M. Graybiel

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Best Female Scientists
2025

D-Index & Metrics

Best Female Scientists

D-Index
138
Citations
71228
World Ranking
258
National Ranking
163

Neuroscience

D-Index
140
Citations
72534
World Ranking
197
National Ranking
128

Research.com Recognitions

  • 2025 - Research.com Best Female Scientists Award
  • 2018 - Gruber Prize in Neuroscience, Society for Neuroscience
  • 2012 - Kavli Prize, The Kavli Foundation for elucidating basic neuronal mechanisms underlying perception and decision
  • 2001 - US President's National Medal of Science "For her pioneering contributions to the understanding of the anatomy and physiology of the brain, including the structure, chemistry, and function of the pathways subserving thought and movement.", Presented by President George W. Bush in a White House East Room ceremony on June 12, 2002.
  • 1994 - Member of the National Academy of Medicine (NAM)
  • 1991 - Fellow of the American Academy of Arts and Sciences
  • 1988 - Member of the National Academy of Sciences
  • 1986 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Ann M. Graybiel is affiliated with MIT in the United States and has a significant body of work in the fields of neuroscience and medicine. Their research focuses primarily on cellular and molecular neuroscience, cognitive neuroscience, neurology, molecular biology, and biomedical engineering.

The scientist has contributed to various main topics, including:

  • Neural dynamics and brain function
  • Neurological disorders and treatments
  • Neuroscience and neuropharmacology research
  • Neuroscience and neural engineering
  • Neurotransmitter receptor influence on behavior
  • Genetic neurodegenerative diseases
  • Receptor mechanisms and signaling

Ann M. Graybiel has published extensively, with recent papers covering significant advances in understanding brain function and related disorders. Selected recent publications include:

  • The Role of the Dorsal-Lateral Prefrontal Cortex in Reward Sensitivity During Approach-Avoidance Conflict, 2021, Cerebral Cortex
  • Computational Phenotyping of Brain-Behavior Dynamics Underlying Approach-Avoidance Conflict in Major Depressive Disorder, 2021, PLoS Computational Biology
  • Striosomes Mediate Value-Based Learning Vulnerable in Age and a Huntington's Disease Model, 2020, Cell
  • Transcriptional Vulnerabilities of Striatal Neurons in Human and Rodent Models of Huntington's Disease, 2023, Nature Communications
  • Dopamine and Beta-Band Oscillations Differentially Link to Striatal Value and Motor Control, 2020, Science Advances

The scientist frequently publishes in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Cell Reports
  • Science Advances
  • The Journal of Comparative Neurology

Ann M. Graybiel has collaborated extensively with other researchers, including frequent coauthors:

  • Tomoko Yoshida
  • Jill R. Crittenden
  • Ken-ichi Amemori
  • Michael J. Cima
  • Helen N. Schwerdt

Throughout their career, the scientist has received multiple awards and honors, such as:

  • Gruber Prize in Neuroscience, Society for Neuroscience, 2018
  • Kavli Prize, The Kavli Foundation, 2012, for elucidating basic neuronal mechanisms underlying perception and decision
  • US President's National Medal of Science, 2001, cited for pioneering contributions to brain anatomy and physiology, presented by President George W. Bush in 2002
  • Member of the National Academy of Medicine, 1994
  • Fellow of the American Academy of Arts and Sciences, 1991
  • Member of the National Academy of Sciences, 1988
  • Fellow of the American Association for the Advancement of Science (AAAS), 1986

Best Publications

  • The substantia nigra of the human brain. II. Patterns of loss of dopamine-containing neurons in Parkinson's disease.

    P. Damier;E. C. Hirsch;Y. Agid;A. M. Graybiel

  • Neurotransmitters and neuromodulators in the basal ganglia

    Ann M. Graybiel

  • Habits, Rituals, and the Evaluative Brain

    Ann M. Graybiel

  • Melanized dopaminergic neurons are differentially susceptible to degeneration in Parkinson's disease

    Etienne Hirsch;Ann M. Graybiel;Yves A. Agid

  • The basal ganglia.

    Ann M. Graybiel

  • A family of cAMP-binding proteins that directly activate Rap1.

    Hiroaki Kawasaki;Gregory M. Springett;Naoki Mochizuki;Shinichiro Toki

  • The basal ganglia and adaptive motor control

    Ann M. Graybiel;Toshihiko Aosaki;Alice W. Flaherty;Minoru Kimura

  • The basal ganglia and chunking of action repertoires.

    Ann M. Graybiel

  • Building neural representations of habits.

    Mandar S. Jog;Yasuo Kubota;Christopher I. Connolly;Viveka Hillegaart

  • Amphetamine and cocaine induce drug-specific activation of the c-fos gene in striosome-matrix compartments and limbic subdivisions of the striatum

    Ann M. Graybiel;Rosario Moratalla;Harold A. Robertson

  • Toward a Neurobiology of Obsessive-Compulsive Disorder

    Ann M Graybiel;Scott L Rauch

  • Dynamic cross-frequency couplings of local field potential oscillations in rat striatum and hippocampus during performance of a T-maze task

    Adriano B. L. Tort;Mark A. Kramer;Catherine Thorn;Daniel J. Gibson

  • The basal ganglia: learning new tricks and loving it.

    Ann M Graybiel

  • Histochemically distinct compartments in the striatum of human, monkeys, and cat demonstrated by acetylthiocholinesterase staining.

    Ann M. Graybiel;Clifton W. Ragsdale

  • Neurobiology of rodent self-grooming and its value for translational neuroscience.

    Allan V. Kalueff;Adam Michael Stewart;Cai Song;Cai Song;Cai Song;Kent C. Berridge

  • Responses of tonically active neurons in the primate's striatum undergo systematic changes during behavioral sensorimotor conditioning

    Toshihiko Aosaki;Hiroshi Tsubokawa;Akihiro Ishida;Katsushige Watanabe

  • The substantia nigra of the human brain. I. Nigrosomes and the nigral matrix, a compartmental organization based on calbindin D(28K) immunohistochemistry.

    P. Damier;E. C. Hirsch;Y. Agid;A. M. Graybiel

  • Activity of striatal neurons reflects dynamic encoding and recoding of procedural memories

    Terra D. Barnes;Yasuo Kubota;Dan Hu;Dezhe Z. Jin;Dezhe Z. Jin

  • Building action repertoires: memory and learning functions of the basal ganglia.

    Ann M Graybiel

  • Neuronal loss in the pedunculopontine tegmental nucleus in Parkinson disease and in progressive supranuclear palsy

    E C Hirsch;A M Graybiel;C Duyckaerts;F Javoy-Agid

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