What is he best known for?
The fields of study he is best known for:
D. James Surmeier spends much of his time researching Neuroscience, Dopamine, Medium spiny neuron, Striatum and Dopaminergic.
The various areas that D. James Surmeier examines in his Neuroscience study include Synaptic plasticity and Neurodegeneration.
His studies deal with areas such as Central nervous system and Anatomy as well as Dopamine.
His work deals with themes such as Glutamatergic, Patch clamp, Postsynaptic potential and Excitatory postsynaptic potential, which intersect with Medium spiny neuron.
His Striatum research includes themes of Electrophysiology and Dopamine receptor D1.
His study looks at the intersection of Dopaminergic and topics like Cell biology with Biochemistry.
His most cited work include:
- Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson’s disease (1210 citations)
- Modulation of Striatal Projection Systems by Dopamine (979 citations)
- D1 and D2 dopamine-receptor modulation of striatal glutamatergic signaling in striatal medium spiny neurons (876 citations)
What are the main themes of his work throughout his whole career to date?
Neuroscience, Medium spiny neuron, Dopamine, Parkinson's disease and Dopaminergic are his primary areas of study.
His is involved in several facets of Neuroscience study, as is seen by his studies on Striatum, Basal ganglia, Substantia nigra, Electrophysiology and Neuron.
His Striatum study incorporates themes from Dendritic spine and Cholinergic.
His studies deal with areas such as Synaptic plasticity, Indirect pathway of movement, Glutamatergic, Excitatory postsynaptic potential and Patch clamp as well as Medium spiny neuron.
The concepts of his Parkinson's disease study are interwoven with issues in Voltage-dependent calcium channel, Neurodegeneration, Mitochondrion and Neuroprotection.
D. James Surmeier has researched Dopaminergic in several fields, including Biochemistry and Cell biology.
He most often published in these fields:
- Neuroscience (78.10%)
- Medium spiny neuron (23.81%)
- Dopamine (22.38%)
What were the highlights of his more recent work (between 2017-2021)?
- Neuroscience (78.10%)
- Parkinson's disease (20.48%)
- Dopaminergic (18.57%)
In recent papers he was focusing on the following fields of study:
D. James Surmeier focuses on Neuroscience, Parkinson's disease, Dopaminergic, Medium spiny neuron and Striatum.
His Neuroscience study combines topics from a wide range of disciplines, such as Electron transport chain and Neurotransmission.
D. James Surmeier has included themes like NMDA receptor, Mitochondrion, Optogenetics and Human brain in his Parkinson's disease study.
His Dopaminergic research incorporates elements of Secretion, Neurodegeneration, Alpha-synuclein and Cell biology.
His biological study spans a wide range of topics, including Ventral tegmental area, Nucleus accumbens, Nerve injury, Basolateral amygdala and Huntingtin.
His Dopamine research integrates issues from Dyskinesia and Levodopa-induced dyskinesia.
Between 2017 and 2021, his most popular works were:
- Striatal synapses, circuits, and Parkinson's disease. (56 citations)
- Negative feedback control of neuronal activity by microglia. (51 citations)
- Allele-selective transcriptional repression of mutant HTT for the treatment of Huntington’s disease (49 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Neuron
- Neurotransmitter
His primary areas of investigation include Parkinson's disease, Neuroscience, Dopaminergic, Cell biology and Striatum.
D. James Surmeier interconnects Cholinergic, Downregulation and upregulation, Transient receptor potential channel, Intracellular and Medium spiny neuron in the investigation of issues within Parkinson's disease.
When carried out as part of a general Neuroscience research project, his work on Dopamine is frequently linked to work in Intermembrane space, therefore connecting diverse disciplines of study.
His Dopaminergic study combines topics in areas such as Isradipine, Pharmacology and In vivo.
His Cell biology research incorporates themes from CASK, Gene knockdown and Synucleinopathies.
His studies in Striatum integrate themes in fields like Synaptic plasticity, Dyskinesia, Levodopa-induced dyskinesia, Brain circuitry and Basal ganglia.
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