World's Best Scientists 2026 revealed!

D-Index & Metrics

Neuroscience

D-Index
80
Citations
22598
World Ranking
1620
National Ranking
794

Biology and Biochemistry

D-Index
80
Citations
22361
World Ranking
4091
National Ranking
2010

Overview

Zhen Yan is affiliated with the University at Buffalo, State University of New York, in the United States. Their research primarily centers on the fields of Biochemistry, Genetics and Molecular Biology, and Neuroscience. The scientist's work spans multiple subfields including Molecular Biology, Genetics, Cellular and Molecular Neuroscience, Cognitive Neuroscience, and Physiology.

Their scholarly output includes significant contributions to topics such as Genetics and Neurodevelopmental Disorders, Epigenetics and DNA Methylation, Autism Spectrum Disorder Research, Alzheimer's Disease Research and Treatments, Neuroscience and Neuropharmacology Research, Neuroendocrine Regulation and Behavior, and Tryptophan and Brain Disorders.

Among their recent notable publications are:

  • Mechanisms of synaptic transmission dysregulation in the prefrontal cortex: pathophysiological implications (2021, Molecular Psychiatry)
  • Dopaminylation of histone H3 in ventral tegmental area regulates cocaine seeking (2020, Science)
  • A standardized social preference protocol for measuring social deficits in mouse models of autism (2020, Nature Protocols)
  • The stressed synapse 2.0: pathophysiological mechanisms in stress-related neuropsychiatric disorders (2021, Nature Reviews Neuroscience)
  • 16p11.2 Copy Number Variations and Neurodevelopmental Disorders (2020, Trends in Neurosciences)

Zhen Yan frequently collaborates with other researchers in their field. Notable frequent co-authors include:

  • Ping Zhong
  • Qing Cao
  • Benjamin Rein
  • Jamal B. Williams
  • Wei Wang

The scientist often publishes in specific venues, with several papers appearing in:

  • Molecular Psychiatry
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cerebral Cortex
  • Nature Communications
  • Neuropsychopharmacology

Best Publications

  • The stressed synapse: the impact of stress and glucocorticoids on glutamate transmission

    Maurizio Popoli;Zhen Yan;Bruce S. McEwen;Gerard Sanacora

  • Coordinated Expression of Dopamine Receptors in Neostriatal Medium Spiny Neurons

    D. James Surmeier;Wen Jie Song;Zhen Yan

  • Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons

    James A. Bibb;Gretchen L. Snyder;Akinori Nishi;Zhen Yan

  • Repeated Stress Causes Cognitive Impairment by Suppressing Glutamate Receptor Expression and Function in Prefrontal Cortex

    Eunice Y. Yuen;Jing Wei;Wenhua Liu;Ping Zhong

  • Acute stress enhances glutamatergic transmission in prefrontal cortex and facilitates working memory

    Eunice Y. Yuen;Wenhua Liu;Ilia N. Karatsoreos;Jian Feng

  • Effects of chronic exposure to cocaine are regulated by the neuronal protein Cdk5

    James A. Bibb;Jingshan Chen;Jane R. Taylor;Per Svenningsson

  • Disrupted-in-Schizophrenia 1 (DISC1) regulates spines of the glutamate synapse via Rac1

    Akiko Hayashi-Takagi;Manabu Takaki;Nick Graziane;Saurav Seshadri

  • Spinophilin regulates the formation and function of dendritic spines

    Jian Feng;Zhen Yan;Adriana B Ferreira;Kazuhito Tomizawa

  • Mechanisms for acute stress-induced enhancement of glutamatergic transmission and working memory.

    Eunice Y. Yuen;Wenhua Liu;Ilia N. Karatsoreos;Yong Ren

  • Protein phosphatase 1 modulation of neostriatal AMPA channels: regulation by DARPP-32 and spinophilin.

    Zhen Yan;Linda Hsieh-Wilson;Jian Feng;Kazuhito Tomizawa

  • Severe deficiencies in dopamine signaling in presymptomatic Huntington's disease mice

    James A. Bibb;Zhen Yan;Per Svenningsson;Gretchen L. Snyder

  • D2 Dopamine Receptors Reduce N-Type Ca2+ Currents in Rat Neostriatal Cholinergic Interneurons Through a Membrane-Delimited, Protein-Kinase-C-Insensitive Pathway

    Zhen Yan;Wen Jie Song;D. James Surmeier

  • Delivery of GABAARs to synapses is mediated by HAP1-KIF5 and disrupted by mutant huntingtin.

    Alison E. Twelvetrees;Eunice Y. Yuen;I. Lorena Arancibia-Carcamo;Andrew F. MacAskill

  • In vivo Cocaine Experience Generates Silent Synapses

    Yanhua H. Huang;Ying Lin;Ping Mu;Brian R. Lee

  • Autism-like Deficits in Shank3-Deficient Mice Are Rescued by Targeting Actin Regulators

    Lara J. Duffney;Ping Zhong;Jing Wei;Emmanuel Matas

  • Parkin controls dopamine utilization in human midbrain dopaminergic neurons derived from induced pluripotent stem cells.

    Houbo Jiang;Yong Ren;Eunice Y. Yuen;Ping Zhong

  • D2 dopamine receptors induce mitogen-activated protein kinase and cAMP response element-binding protein phosphorylation in neurons

    Zhen Yan;Jian Feng;Allen A. Fienberg;Paul Greengard

  • Serotonin receptors modulate GABA(A) receptor channels through activation of anchored protein kinase C in prefrontal cortical neurons.

    Jian Feng;Xiang Cai;Jinghui Zhao;Zhen Yan

  • Potentiation of NMDA receptor currents by dopamine D1 receptors in prefrontal cortex

    Guojun Chen;Paul Greengard;Zhen Yan

  • Regulation of NMDA Receptors by Neuregulin Signaling in Prefrontal Cortex

    Zhenglin Gu;Qian Jiang;Amy Kit Yu Fu;Nancy Yuk-Yu Ip

Frequent Co-Authors

Jian Feng
Jian Feng University at Buffalo, State University of New York
Paul Greengard
Paul Greengard Rockefeller University
Stephen J. Moss
Stephen J. Moss Tufts University
Josef T. Kittler
Josef T. Kittler University College London
Angus C. Nairn
Angus C. Nairn Yale University
D. James Surmeier
D. James Surmeier Northwestern University
Akinori Nishi
Akinori Nishi Kurume University
Akira Sawa
Akira Sawa Johns Hopkins University
Charles C. Ouimet
Charles C. Ouimet Florida State University
Allen A. Fienberg
Allen A. Fienberg Rockefeller University

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