His scientific interests lie mostly in Neuroscience, Nucleus accumbens, Silent synapse, Dopamine and Receptor. His work in the fields of Neuroscience, such as Excitatory postsynaptic potential, overlaps with other areas such as Prefrontal cortex. His Excitatory postsynaptic potential research is multidisciplinary, incorporating perspectives in Synaptic plasticity and Metaplasticity.
The various areas that Yan Dong examines in his Nucleus accumbens study include Patch clamp and CREB. His Silent synapse research focuses on Neuroplasticity and how it relates to Glutamatergic. His study looks at the relationship between Dopamine and topics such as Addiction, which overlap with Drug, Pharmacology and Dopamine receptor D2.
Yan Dong mainly focuses on Neuroscience, Nucleus accumbens, Excitatory postsynaptic potential, Addiction and Silent synapse. His research in Neuroscience is mostly concerned with Neuroplasticity. His Nucleus accumbens study integrates concerns from other disciplines, such as NMDA receptor, Glutamate receptor and Basolateral amygdala, Amygdala.
In his research, Adenylyl cyclase and Dopamine receptor D2 is intimately related to Membrane potential, which falls under the overarching field of Excitatory postsynaptic potential. He interconnects Drug taking, Drug, Abstinence and Lateral habenula in the investigation of issues within Addiction. The study incorporates disciplines such as Dendritic spine and Developmental maturation in addition to Silent synapse.
His main research concerns Neuroscience, Nucleus accumbens, Glutamatergic, AMPA receptor and Silent synapse. His research integrates issues of Glutamate receptor and Neurotransmission in his study of Neuroscience. The concepts of his Neurotransmission study are interwoven with issues in Synaptic plasticity, Postsynaptic potential and Cell biology.
His Nucleus accumbens research integrates issues from Self-administration, Basolateral amygdala and Excitatory postsynaptic potential. His AMPA receptor research is multidisciplinary, relying on both Developmental maturation, Glutamatergic synapse and Synapse maturation. His Silent synapse study integrates concerns from other disciplines, such as Synapse, Gene knockdown and Synaptogenesis.
Yan Dong mainly investigates Neuroscience, AMPA receptor, Nucleus accumbens, Silent synapse and Addiction. His Neuroscience study combines topics in areas such as Histone methyltransferase, Transcription, Transcription factor, Zinc finger and Regulator. His work investigates the relationship between AMPA receptor and topics such as Excitatory postsynaptic potential that intersect with problems in Homeostatic plasticity, Downregulation and upregulation and NMDA receptor.
His work deals with themes such as Addictive behavior, Reward system, Biological neural network, Opioid and Neuroplasticity, which intersect with Nucleus accumbens. His Silent synapse research is multidisciplinary, incorporating perspectives in Developmental maturation, Cocaine seeking, Synapse maturation and Postsynaptic density. His Addiction research is multidisciplinary, incorporating elements of Glutamate receptor, Reward learning, Affect and Lateral habenula.
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Drugs of abuse and stress trigger a common synaptic adaptation in dopamine neurons.
Daniel Saal;Yan Dong;Antonello Bonci;Robert C Malenka.
Neuron (2003)
Transient neuronal inhibition reveals opposing roles of indirect and direct pathways in sensitization
Susan M Ferguson;Daniel Eskenazi;Masago Ishikawa;Matthew J Wanat.
Nature Neuroscience (2011)
CREB modulates excitability of nucleus accumbens neurons
Yan Dong;Thomas Green;Daniel Saal;Helene Marie.
Nature Neuroscience (2006)
Sex-specific transcriptional signatures in human depression.
Benoit Labonté;Olivia Engmann;Immanuel Purushothaman;Caroline Menard.
Nature Medicine (2017)
Activation of intestinal CFTR Cl- channel by heat-stable enterotoxin and guanylin via cAMP-dependent protein kinase.
A.C. Chao;F.J. de Sauvage;Y.J. Dong;J.A. Wagner.
The EMBO Journal (1994)
In vivo Cocaine Experience Generates Silent Synapses
Yanhua H. Huang;Ying Lin;Ping Mu;Brian R. Lee.
Neuron (2009)
Bidirectional Modulation of Incubation of Cocaine Craving by Silent Synapse-Based Remodeling of Prefrontal Cortex to Accumbens Projections
Yao Ying Ma;Brian R. Lee;Xiusong Wang;Changyong Guo.
Neuron (2014)
Maturation of silent synapses in amygdala-accumbens projection contributes to incubation of cocaine craving
Brian R. Lee;Yao Ying Ma;Yanhua H. Huang;Xiusong Wang.
Nature Neuroscience (2013)
A schizophrenia-related sensorimotor deficit links α3-containing GABAA receptors to a dopamine hyperfunction
B. K. Yee;R. Keist;L. Von Boehmer;R. Studer.
Proceedings of the National Academy of Sciences of the United States of America (2005)
Cocaine-induced potentiation of synaptic strength in dopamine neurons: Behavioral correlates in GluRA(–/–) mice
Y. Dong;D. Saal;M. Thomas;R. Faust.
Proceedings of the National Academy of Sciences of the United States of America (2004)
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