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Neuroscience

D-Index
38
Citations
6722
World Ranking
8519
National Ranking
3630

Overview

Xiu-Ti Hu is affiliated with Rush University Medical Center in the United States. Their research primarily focuses on neuroscience, with particular emphasis on cellular and molecular neuroscience, cognitive neuroscience, physiology, neurology, and molecular biology.

Their work covers a range of topics including:

  • Neuroscience and Neuropharmacology Research
  • Neurotransmitter Receptor Influence on Behavior
  • Alzheimer's disease research and treatments
  • Memory and Neural Mechanisms
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Neural dynamics and brain function
  • Forensic Toxicology and Drug Analysis

The scientist has contributed to multiple publications, with notable papers such as:

  • Ca2+ channel blockade reduces cocaine's vasoconstriction and neurotoxicity in the prefrontal cortex, 2021, Translational Psychiatry
  • Hyperactivity of medial prefrontal cortex pyramidal neurons occurs in a mouse model of early-stage Alzheimer's disease without β-amyloid accumulation, 2023, Frontiers in Pharmacology
  • Memantine Attenuates Cocaine and neuroHIV Neurotoxicity in the Medial Prefrontal Cortex, 2022, Frontiers in Pharmacology
  • Triumeq Increases Excitability of Pyramidal Neurons in the Medial Prefrontal Cortex by Facilitating Voltage-Gated Ca2+ Channel Function, 2021, Frontiers in Pharmacology
  • HIV-Induced Hyperactivity of Striatal Neurons Is Associated with Dysfunction of Voltage-Gated Calcium and Potassium Channels at Middle Age, 2022, Membranes

Frequent coauthors in their research include:

  • Lena Al-Harthi
  • Lihua Chen
  • Congwu Du
  • Kicheon Park
  • Craig P. Allen

Xiu-Ti Hu's publications are most often found in the following venues:

  • Frontiers in Pharmacology
  • Translational Psychiatry
  • Membranes
  • Alzheimer's & Dementia

Overall, the body of work by Xiu-Ti Hu emphasizes neuropharmacological mechanisms and neural dynamics, particularly in relation to disease states such as Alzheimer's disease and neurotoxicity linked to substance use and HIV.

Best Publications

  • Elimination of cocaine-induced hyperactivity and dopamine-mediated neurophysiological effects in dopamine D1 receptor mutant mice

    Ming Xu;Xiu-Ti Hu;Donald C. Cooper;Rosario Moratalla

  • Dopamine D3 Receptor Mutant Mice Exhibit Increased Behavioral Sensitivity to Concurrent Stimulation of D1 and D2 Receptors

    Ming Xu;Timothy E Koeltzow;Giovanni Tirado Santiago;Rosario Moratalla

  • REPEATED ADMINISTRATION OF COCAINE OR AMPHETAMINE ALTERS NEURONAL RESPONSES TO GLUTAMATE IN THE MESOACCUMBENS DOPAMINE SYSTEM

    F. J. White;Xiu-Ti Hu;Xu-Feng Zhang;M. E. Wolf

  • Effects of lesions of prefrontal cortex, amygdala, or fornix on behavioral sensitization to amphetamine: Comparison with N-methyl-d-aspartate antagonists

    M.E. Wolf;S.L. Dahlin;X.-T. Hu;C.-J. Xue

  • Increased Responsiveness of Ventral Tegmental Area Dopamine Neurons to Glutamate after Repeated Administration of Cocaine or Amphetamine Is Transient and Selectively Involves AMPA Receptors

    Xu Feng Zhang;Xiu Ti Hu;Francis J. White;Marina E. Wolf

  • Loss of autoreceptor functions in mice lacking the dopamine transporter

    Sara R. Jones;Sara R. Jones;Raul R. Gainetdinov;Raul R. Gainetdinov;Xiu Ti Hu;Donald C. Cooper

  • Alterations in Dopamine Release But Not Dopamine Autoreceptor Function in Dopamine D3 Receptor Mutant Mice

    Timothy E. Koeltzow;Ming Xu;Donald C. Cooper;Xiu Ti Hu

  • MK-801 prevents alterations in the mesoaccumbens dopamine system associated with behavioral sensitization to amphetamine

    Marina E. Wolf;Francis J. White;Xiu Ti Hu

  • Whole-Cell Plasticity in Cocaine Withdrawal: Reduced Sodium Currents in Nucleus Accumbens Neurons

    Xu-Feng Zhang;Xiu-Ti Hu;Francis J. White

  • Both glutamate receptor antagonists and prefrontal cortex lesions prevent induction of cocaine sensitization and associated neuroadaptations.

    Yong Li;Xiu Ti Hu;Timothy G. Berney;A. John Vartanian

  • Excitability of Dopamine Neurons: Modulation and Physiological Consequences

    Michela "Micky" Marinelli;C. N. Rudick;X. T. Hu;F. J. White

  • D1 dopamine receptor stimulation enables the postsynaptic, but not autoreceptor, effects of D2 dopamine agonists in nigrostriatal and mesoaccumbens dopamine systems

    Stephen R. Wachtel;Xiu‐Ti Hu;Matthew P. Galloway;Francis J. White

  • Lesions of the nigrostriatal dopamine projection increase the inhibitory effects of D1 and D2 dopamine agonists on caudate-putamen neurons and relieve D2 receptors from the necessity of D1 receptor stimulation.

    Xiu-Ti Hu;S. R. Wachtel;M. P. Galloway;F. J. White

  • Comparison of effects of D-1 and D-2 dopamine receptor agonists on neurons in the rat caudate putamen: an electrophysiological study

    Xiu-Ti Hu;Rex Y. Wang

  • Dopamine receptor antagonists fail to prevent induction of cocaine sensitization.

    Francis J White;Amit Joshi;Timothy E Koeltzow;Xiu-Ti Hu

  • Dopamine D2 Receptor Modulation of K+ Channel Activity Regulates Excitability of Nucleus Accumbens Neurons at Different Membrane Potentials

    Mariela F. Perez;Francis J. White;Xiu-Ti Hu

  • Cocaine-induced plasticity of intrinsic membrane properties in prefrontal cortex pyramidal neurons: adaptations in potassium currents.

    Yan Dong;Fernando J. Nasif;Jennifer J. Tsui;William Y. Ju

  • Differential effects of acute clozapine and haloperidol on the activity of ventral tegmental (A10) and nigrostriatal (A9) dopamine neurons

    Timothy H. Hand;Xiu-Ti Hu;Rex Y. Wang

  • Homeostatic synapse-driven membrane plasticity in nucleus accumbens neurons.

    Masago Ishikawa;Ping Mu;Jason T. Moyer;John A. Wolf

  • Dopamine enhances glutamate-induced excitation of rat striatal neurons by cooperative activation of D1 and D2 class receptors

    Xiu-Ti Hu;Francis J White

  • Adaptations in the mesoaccumbens dopamine system resulting from repeated administration of dopamine D1 and D2 receptor-selective agonists : relevance to cocaine sensitization

    Henry Dj;Hu Xt;White Fj

Frequent Co-Authors

Marina E. Wolf
Marina E. Wolf Oregon Health & Science University
Donald C. Cooper
Donald C. Cooper University of Colorado Boulder
T. Celeste Napier
T. Celeste Napier Rush University Medical Center
Yan Dong
Yan Dong University of Pittsburgh
Sara R. Jones
Sara R. Jones Wake Forest University
Rosario Moratalla
Rosario Moratalla Spanish National Research Council
Fatah Kashanchi
Fatah Kashanchi George Mason University
Nora D. Volkow
Nora D. Volkow National Institutes of Health

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