World's Best Scientists 2026 revealed!
William A. Carlezon

William A. Carlezon

D-Index & Metrics

Neuroscience

D-Index
84
Citations
28884
World Ranking
1380
National Ranking
696

Medicine

D-Index
84
Citations
28929
World Ranking
14996
National Ranking
7580

Overview

William A. Carlezon is affiliated with Harvard University in the United States. Their primary field of study is Neuroscience, with a focus on several subfields including Cognitive Neuroscience, Behavioral Neuroscience, Cellular and Molecular Neuroscience, Social Psychology, and Biological Psychiatry.

The main research topics covered by Carlezon's work include:

  • Stress Responses and Cortisol
  • Neuroendocrine Regulation and Behavior
  • Tryptophan and Brain Disorders
  • Sleep and Wakefulness Research
  • Memory and Neural Mechanisms
  • Neurotransmitter Receptor Influence on Behavior
  • Neuropeptides and Animal Physiology

Carlezon's recent publications demonstrate a focus on neuropsychiatric disorders, stress, and neural circuit mechanisms. These include:

  • "Post-traumatic stress disorder: clinical and translational neuroscience from cells to circuits," 2022, Nature Reviews Neurology
  • "Nucleus Accumbens Medium Spiny Neuron Subtypes Differentially Regulate Stress-Associated Alterations in Sleep Architecture," 2021, Biological Psychiatry
  • "Single-Nucleus Transcriptome Profiling of Dorsolateral Prefrontal Cortex: Mechanistic Roles for Neuronal Gene Expression, Including the 17q21.31 Locus, in PTSD Stress Response," 2023, American Journal of Psychiatry
  • "Genome-wide translational profiling of amygdala Crh-expressing neurons reveals role for CREB in fear extinction learning," 2020, Nature Communications
  • "Concordant neurophysiological signatures of cognitive control in humans and rats," 2021, Neuropsychopharmacology

Frequent co-authors working with Carlezon include:

  • Scott L. Rauch
  • Anissa Abi-Dargham
  • New York
  • Deanna M. Barch
  • St Louis

The scientist frequently publishes in venues such as:

  • Biological Psychiatry
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Neuropsychopharmacology
  • Nature Communications
  • Proceedings of the National Academy of Sciences

Best Publications

  • The Mesolimbic Dopamine Reward Circuit in Depression

    Eric J. Nestler;William A. Carlezon

  • The many faces of CREB

    William A. Carlezon;Ronald S. Duman;Eric J. Nestler

  • Regulation of Cocaine Reward by CREB

    William A. Carlezon;Johannes Thome;Valerie G. Olson;Sarah B. Lane-Ladd

  • Mania-like behavior induced by disruption of CLOCK.

    Kole Roybal;David Theobold;Ami Graham;Jennifer A. DiNieri

  • Expression of the transcription factor ΔFosB in the brain controls sensitivity to cocaine

    Max B. Kelz;Jingshan Chen;William A. Carlezon;William A. Carlezon;Kim Whisler

  • GTP cyclohydrolase and tetrahydrobiopterin regulate pain sensitivity and persistence

    Irmgard Tegeder;Michael Costigan;Robert S Griffin;Andrea Abele

  • Biological substrates of reward and aversion: a nucleus accumbens activity hypothesis.

    William A. Carlezon;Mark J. Thomas

  • Altered Responsiveness to Cocaine and Increased Immobility in the Forced Swim Test Associated with Elevated cAMP Response Element-Binding Protein Expression in Nucleus Accumbens

    Andrea M. Pliakas;Richard R. Carlson;Rachael L. Neve;Christine Konradi

  • Antidepressant-Like Effects of κ-Opioid Receptor Antagonists in the Forced Swim Test in Rats

    Stephen D. Mague;Andrea M. Pliakas;Mark S. Todtenkopf;Hilarie C. Tomasiewicz

  • Long-term memory is facilitated by cAMP response element-binding protein overexpression in the amygdala.

    Sheena A. Josselyn;Chanjun Shi;William A. Carlezon;William A. Carlezon;Rachael L. Neve

  • Dynorphin, stress, and depression

    Allison T. Knoll;William A. Carlezon

  • Post-traumatic stress disorder: clinical and translational neuroscience from cells to circuits

    Unknown

  • Depressive-Like Effects of the κ-Opioid Receptor Agonist Salvinorin A on Behavior and Neurochemistry in Rats

    William A. Carlezon;Cécile Béguin;Jennifer A. DiNieri;Michael H. Baumann

  • Rewarding Actions of Phencyclidine and Related Drugs in Nucleus Accumbens Shell and Frontal Cortex

    William A. Carlezon;Roy A. Wise

  • Intracranial self-stimulation (ICSS) in rodents to study the neurobiology of motivation.

    William A Carlezon;Elena H Chartoff

  • Fear Conditioning Occludes LTP-Induced Presynaptic Enhancement of Synaptic Transmission in the Cortical Pathway to the Lateral Amygdala

    Evgeny Tsvetkov;William A. Carlezon;Francine M. Benes;Eric R. Kandel

  • Elevated levels of GluR1 in the midbrain: a trigger for sensitization to drugs of abuse?

    William A. Carlezon;Eric J. Nestler

  • Anxiolytic-like effects of kappa-opioid receptor antagonists in models of unlearned and learned fear in rats.

    Allison T. Knoll;Edward G. Meloni;James B. Thomas;F. Ivy Carroll

  • Effects of κ-opioid receptor ligands on intracranial self-stimulation in rats

    Mark S. Todtenkopf;Jacqueline F. Marcus;Philip S. Portoghese;William A. Carlezon

  • Sensitization to morphine induced by viral-mediated gene transfer

    William A. Carlezon;Virginia A. Boundy;Virginia A. Boundy;Colin N. Haile;Colin N. Haile;Sarah B. Lane;Sarah B. Lane

  • Altered responsiveness to cocaine in rats exposed to methylphenidate during development.

    Susan L. Andersen;Andreas Arvanitogiannis;Andrea M. Pliakas;Celeste LeBlanc

Frequent Co-Authors

Bruce M. Cohen
Bruce M. Cohen Harvard University
Eric J. Nestler
Eric J. Nestler Icahn School of Medicine at Mount Sinai
Rachael L. Neve
Rachael L. Neve Harvard University
Lee-Yuan Liu-Chen
Lee-Yuan Liu-Chen Temple University
Christopher J. McDougle
Christopher J. McDougle Harvard University
Roy A. Wise
Roy A. Wise National Institute on Drug Abuse
F. Ivy Carroll
F. Ivy Carroll Research Triangle Park Foundation
Vadim Y. Bolshakov
Vadim Y. Bolshakov Harvard University
Kerry J. Ressler
Kerry J. Ressler Harvard University
Wei Xu
Wei Xu Shenzhen University

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