His primary areas of study are Neuroscience, Pharmacology, Nucleus accumbens, Addiction and Endocrinology. His research on Neuroscience frequently links to adjacent areas such as Neurotransmission. His study looks at the relationship between Pharmacology and fields such as Endogenous opioid, as well as how they intersect with chemical problems.
His Nucleus accumbens study incorporates themes from NMDA receptor, Phencyclidine and Nicotine. His biological study spans a wide range of topics, including AMPA receptor, Epigenetics of cocaine addiction and Stimulant. His study looks at the relationship between Endocrinology and topics such as Dynorphin, which overlap with κ-opioid receptor, Behavioural despair test, CREB and Stimulation.
The scientist’s investigation covers issues in Neuroscience, Internal medicine, Endocrinology, Pharmacology and Nucleus accumbens. William A. Carlezon works mostly in the field of Neuroscience, limiting it down to topics relating to κ-opioid receptor and, in certain cases, Endogenous opioid, as a part of the same area of interest. His study explores the link between Internal medicine and topics such as Anxiety that cross with problems in Clinical psychology.
His research investigates the connection with Endocrinology and areas like Dynorphin which intersect with concerns in Behavioural despair test. His study looks at the intersection of Pharmacology and topics like Brain stimulation reward with Medial forebrain bundle. The Nucleus accumbens study combines topics in areas such as AMPA receptor, Striatum, CREB and Basal ganglia.
His primary scientific interests are in Neuroscience, Endocrinology, Internal medicine, Nucleus accumbens and Dopamine. His Neuroscience research incorporates themes from Synaptic plasticity, Transcriptome and Behavioral test. His Endocrinology study combines topics in areas such as Inflammation and Receptor.
The various areas that William A. Carlezon examines in his Internal medicine study include Offspring, Anxiety, Sleep in non-human animals, Autism spectrum disorder and Addiction. His research integrates issues of Glutamate receptor, Ventral tegmental area and Social defeat in his study of Nucleus accumbens. The concepts of his Dopamine study are interwoven with issues in Agonist, Methamphetamine, Stimulation and Sensitization.
William A. Carlezon spends much of his time researching Neuroscience, Nucleus accumbens, κ-opioid receptor, Social defeat and Amygdala. In his study, William A. Carlezon carries out multidisciplinary Neuroscience and Behavioral methods research. William A. Carlezon mostly deals with Brain stimulation reward in his studies of Nucleus accumbens.
His κ-opioid receptor research is multidisciplinary, relying on both Dynorphin, Neuron, Anhedonia and Circadian rhythm. His Anhedonia study frequently links to adjacent areas such as Internal medicine. William A. Carlezon interconnects Nociceptin receptor, Striatum, Ventral tegmental area, Curiosity and Anterior cingulate cortex in the investigation of issues within Social defeat.
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The Mesolimbic Dopamine Reward Circuit in Depression
Eric J. Nestler;William A. Carlezon.
Biological Psychiatry (2006)
The many faces of CREB
William A. Carlezon;Ronald S. Duman;Eric J. Nestler.
Trends in Neurosciences (2005)
Regulation of Cocaine Reward by CREB
William A. Carlezon;Johannes Thome;Valerie G. Olson;Sarah B. Lane-Ladd.
Science (1998)
Mania-like behavior induced by disruption of CLOCK.
Kole Roybal;David Theobold;Ami Graham;Jennifer A. DiNieri.
Proceedings of the National Academy of Sciences of the United States of America (2007)
Expression of the transcription factor ΔFosB in the brain controls sensitivity to cocaine
Max B. Kelz;Jingshan Chen;William A. Carlezon;William A. Carlezon;Kim Whisler.
Nature (1999)
GTP cyclohydrolase and tetrahydrobiopterin regulate pain sensitivity and persistence
Irmgard Tegeder;Irmgard Tegeder;Michael Costigan;Robert S Griffin;Andrea Abele.
Nature Medicine (2006)
Altered Responsiveness to Cocaine and Increased Immobility in the Forced Swim Test Associated with Elevated cAMP Response Element-Binding Protein Expression in Nucleus Accumbens
Andrea M. Pliakas;Richard R. Carlson;Rachael L. Neve;Christine Konradi.
The Journal of Neuroscience (2001)
Biological substrates of reward and aversion: a nucleus accumbens activity hypothesis.
William A. Carlezon;Mark J. Thomas.
Neuropharmacology (2009)
Antidepressant-Like Effects of κ-Opioid Receptor Antagonists in the Forced Swim Test in Rats
Stephen D. Mague;Andrea M. Pliakas;Mark S. Todtenkopf;Hilarie C. Tomasiewicz.
Journal of Pharmacology and Experimental Therapeutics (2003)
Long-term memory is facilitated by cAMP response element-binding protein overexpression in the amygdala.
Sheena A. Josselyn;Chanjun Shi;William A. Carlezon;William A. Carlezon;Rachael L. Neve.
The Journal of Neuroscience (2001)
Neuropsychopharmacology
(Impact Factor: 8.294)
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