Sic L. Chan

Overview

Best Publications

• Gut-expressed gustducin and taste receptors regulate secretion of glucagon-like peptide-1

  Hyeung-Jin Jang;Zaza Kokrashvili;Michael J. Theodorakis;Olga D. Carlson

  1131
  Citations

• Homocysteine Elicits a DNA Damage Response in Neurons That Promotes Apoptosis and Hypersensitivity to Excitotoxicity

  Inna I. Kruman;Carsten Culmsee;Sic L. Chan;Yuri Kruman

  1025
  Citations

• Calcium signaling in the ER: its role in neuronal plasticity and neurodegenerative disorders

  Mark P Mattson;Frank M LaFerla;Sic L Chan;Malcolm A Leissring

  643
  Citations

• Neuronal and glial calcium signaling in Alzheimer's disease.

  Mark P Mattson;Mark P Mattson;Sic L Chan

  641
  Citations

• Caspase and calpain substrates: Roles in synaptic plasticity and cell death

  Sic L. Chan;Mark P. Mattson

  622
  Citations

• Calcium orchestrates apoptosis.

  Mark P Mattson;Sic L Chan

  620
  Citations

• Disruption of neurogenesis by amyloid β-peptide, and perturbed neural progenitor cell homeostasis, in models of Alzheimer's disease

  Norman J. Haughey;Avi Nath;Sic L. Chan;A. C. Borchard

  606
  Citations

• Modification of Brain Aging and Neurodegenerative Disorders by Genes, Diet, and Behavior

  Mark P. Mattson;Sic L. Chan;Wenzhen Duan

  587
  Citations

• DAPK1 Interaction with NMDA Receptor NR2B Subunits Mediates Brain Damage in Stroke

  Weihong Tu;Xin Xu;Lisheng Peng;Xiaofen Zhong

  565
  Citations

• Cell Cycle Activation Linked to Neuronal Cell Death Initiated by DNA Damage

  Inna I Kruman;Robert P Wersto;Fernando Cardozo-Pelaez;Lubomir Smilenov

  454
  Citations

• Presenilin-1 Mutations Increase Levels of Ryanodine Receptors and Calcium Release in PC12 Cells and Cortical Neurons

  Sic L. Chan;Michael Mayne;Clark P. Holden;Jonathan D. Geiger

  449
  Citations

• Neutralization of transthyretin reverses the neuroprotective effects of secreted amyloid precursor protein (APP) in APPSW mice resulting in tau phosphorylation and loss of hippocampal neurons: support for the amyloid hypothesis.

  Thor D. Stein;Nicholas J. Anders;Charles DeCarli;Sic L. Chan

  417
  Citations

• A synthetic inhibitor of p53 protects neurons against death induced by ischemic and excitotoxic insults, and amyloid beta-peptide.

  Carsten Culmsee;Xiaoxiang Zhu;Qian Sheng Yu;Sic L. Chan

  384
  Citations

• Involvement of Notch signaling in hippocampal synaptic plasticity

  Yue Wang;Sic L. Chan;Lucio Miele;Pamela J. Yao

  328
  Citations

• Gamma secretase–mediated Notch signaling worsens brain damage and functional outcome in ischemic stroke

  Thiruma V. Arumugam;Sic L. Chan;Dong Gyu Jo;Gokhan Yilmaz

  297
  Citations

• Intravenous immunoglobulin (IVIG) protects the brain against experimental stroke by preventing complement-mediated neuronal cell death

  Thiruma V. Arumugam;Sung Chun Tang;Justin D. Lathia;Aiwu Cheng

  253
  Citations

• Dysregulation of cellular calcium homeostasis in Alzheimer's disease: bad genes and bad habits.

  Mark P. Mattson;Sic L. Chan

  246
  Citations

• Receptor channel TRPC6 is a key mediator of Notch-driven glioblastoma growth and invasiveness

  Srinivasulu Chigurupati;Rajarajeswari Venkataraman;Daniel Barrera;Anusha Naganathan

  221
  Citations

• p38 MAP kinase mediates nitric oxide-induced apoptosis of neural progenitor cells.

  Aiwu Cheng;Sic L. Chan;Ollivier Milhavet;Shuqin Wang

  217
  Citations

• 2-Deoxy-D-glucose protects hippocampal neurons against excitotoxic and oxidative injury: evidence for the involvement of stress proteins.

  Jaewon Lee;Annadora J. Bruce-Keller;Yuri Kruman;Sic L. Chan

  209
  Citations