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Sic L. Chan

D-Index & Metrics

Biology and Biochemistry

D-Index
56
Citations
15097
World Ranking
14231
National Ranking
6000

Sic L. Chan publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Sic L. Chan sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 99 publications — 5th percentile

5% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Sic L. Chan D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Sic L. Chan sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 56 D-Index — 28th percentile

28% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Sic L. Chan is affiliated with the University of Central Florida in the United States. Their research spans multiple fields within biochemistry, genetics, molecular biology, and medicine, with a particular concentration in molecular biology and physiology. Their work also covers diverse topics including ion transport and channel regulation, Alzheimer's disease research and treatments, aluminum toxicity and tolerance in plants and animals, cancer, hypoxia and metabolism, mitochondrial function and pathology, and adipose tissue and metabolism.

Their recent published papers include the following:

  • Neuronal Aquaporin 1 Inhibits Amyloidogenesis by Suppressing the Interaction Between Beta-Secretase and Amyloid Precursor Protein, 2020, The Journals of Gerontology Series A
  • Depletion of HIF-1α-mediated Mitochondrial Uncoupling Protein-4 (UCP4) Expression Sensitizes Temozolomide (TMZ)-Induced Apoptosis in Glioblastoma, 2020, The FASEB Journal
  • Correction to "A synthetic inhibitor of p53 protects neurons against death induced by ischemic and excitotoxic insults, and amyloid β-peptide", 2024, Journal of Neurochemistry

Frequent coauthors in their collaborations include:

  • Mark P. Mattson
  • Jinsu Park
  • Meenu Madan
  • Srinivasulu Chigurupati
  • Seung Hyun Baek

Their scholarly output has appeared in several notable venues, including:

  • The Journals of Gerontology Series A
  • The FASEB Journal
  • Journal of Neurochemistry

Best Publications

  • Gut-expressed gustducin and taste receptors regulate secretion of glucagon-like peptide-1

    Hyeung-Jin Jang;Zaza Kokrashvili;Michael J. Theodorakis;Olga D. Carlson

  • Homocysteine Elicits a DNA Damage Response in Neurons That Promotes Apoptosis and Hypersensitivity to Excitotoxicity

    Inna I. Kruman;Carsten Culmsee;Sic L. Chan;Yuri Kruman

  • Calcium signaling in the ER: its role in neuronal plasticity and neurodegenerative disorders

    Mark P Mattson;Frank M LaFerla;Sic L Chan;Malcolm A Leissring

  • Neuronal and glial calcium signaling in Alzheimer's disease.

    Mark P Mattson;Mark P Mattson;Sic L Chan

  • Caspase and calpain substrates: Roles in synaptic plasticity and cell death

    Sic L. Chan;Mark P. Mattson

  • Calcium orchestrates apoptosis.

    Mark P Mattson;Sic L Chan

  • Disruption of neurogenesis by amyloid β-peptide, and perturbed neural progenitor cell homeostasis, in models of Alzheimer's disease

    Norman J. Haughey;Avi Nath;Sic L. Chan;A. C. Borchard

  • Modification of Brain Aging and Neurodegenerative Disorders by Genes, Diet, and Behavior

    Mark P. Mattson;Sic L. Chan;Wenzhen Duan

  • DAPK1 Interaction with NMDA Receptor NR2B Subunits Mediates Brain Damage in Stroke

    Weihong Tu;Xin Xu;Lisheng Peng;Xiaofen Zhong

  • Cell Cycle Activation Linked to Neuronal Cell Death Initiated by DNA Damage

    Inna I Kruman;Robert P Wersto;Fernando Cardozo-Pelaez;Lubomir Smilenov

  • Presenilin-1 Mutations Increase Levels of Ryanodine Receptors and Calcium Release in PC12 Cells and Cortical Neurons

    Sic L. Chan;Michael Mayne;Clark P. Holden;Jonathan D. Geiger

  • Neutralization of transthyretin reverses the neuroprotective effects of secreted amyloid precursor protein (APP) in APPSW mice resulting in tau phosphorylation and loss of hippocampal neurons: support for the amyloid hypothesis.

    Thor D. Stein;Nicholas J. Anders;Charles DeCarli;Sic L. Chan

  • A synthetic inhibitor of p53 protects neurons against death induced by ischemic and excitotoxic insults, and amyloid beta-peptide.

    Carsten Culmsee;Xiaoxiang Zhu;Qian Sheng Yu;Sic L. Chan

  • Involvement of Notch signaling in hippocampal synaptic plasticity

    Yue Wang;Sic L. Chan;Lucio Miele;Pamela J. Yao

  • Gamma secretase–mediated Notch signaling worsens brain damage and functional outcome in ischemic stroke

    Thiruma V. Arumugam;Sic L. Chan;Dong Gyu Jo;Gokhan Yilmaz

  • Intravenous immunoglobulin (IVIG) protects the brain against experimental stroke by preventing complement-mediated neuronal cell death

    Thiruma V. Arumugam;Sung Chun Tang;Justin D. Lathia;Aiwu Cheng

  • Dysregulation of cellular calcium homeostasis in Alzheimer's disease: bad genes and bad habits.

    Mark P. Mattson;Sic L. Chan

  • Receptor channel TRPC6 is a key mediator of Notch-driven glioblastoma growth and invasiveness

    Srinivasulu Chigurupati;Rajarajeswari Venkataraman;Daniel Barrera;Anusha Naganathan

  • p38 MAP kinase mediates nitric oxide-induced apoptosis of neural progenitor cells.

    Aiwu Cheng;Sic L. Chan;Ollivier Milhavet;Shuqin Wang

  • 2-Deoxy-D-glucose protects hippocampal neurons against excitotoxic and oxidative injury: evidence for the involvement of stress proteins.

    Jaewon Lee;Annadora J. Bruce-Keller;Yuri Kruman;Sic L. Chan

Frequent Co-Authors

Mark P. Mattson
Mark P. Mattson Johns Hopkins University
Thiruma V. Arumugam
Thiruma V. Arumugam La Trobe University
Dong-Gyu Jo
Dong-Gyu Jo Sungkyunkwan University
Jaewon Lee
Jaewon Lee Pusan National University
Nigel H. Greig
Nigel H. Greig National Institutes of Health
Carsten Culmsee
Carsten Culmsee Philipp University of Marburg
Justin D. Lathia
Justin D. Lathia Cleveland Clinic Lerner College of Medicine
Norman J. Haughey
Norman J. Haughey Tulane University
Avindra Nath
Avindra Nath National Institutes of Health
Joseph D. Buxbaum
Joseph D. Buxbaum Icahn School of Medicine at Mount Sinai

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Best Scientists Citing Sic L. Chan

Mark P. Mattson

Mark P. Mattson

Johns Hopkins University

Publications: 328

Thiruma V. Arumugam

Thiruma V. Arumugam

La Trobe University

Publications: 81

Dong-Gyu Jo

Dong-Gyu Jo

Sungkyunkwan University

Publications: 39

Nigel H. Greig

Nigel H. Greig

National Institutes of Health

Publications: 36

George Perry

George Perry

The University of Texas at San Antonio

Publications: 34

Avindra Nath

Avindra Nath

National Institutes of Health

Publications: 26

Ilya Bezprozvanny

Ilya Bezprozvanny

The University of Texas Southwestern Medical Center

Publications: 26

Youming Lu

Youming Lu

Huazhong University of Science and Technology

Publications: 25

D. Allan Butterfield

D. Allan Butterfield

University of Kentucky

Publications: 25

Thomas B. Shea

Thomas B. Shea

University of Massachusetts Lowell

Publications: 24

Fiona M. Gribble

Fiona M. Gribble

University of Cambridge

Publications: 24

Alexei Verkhratsky

Alexei Verkhratsky

University of Manchester

Publications: 23

Frank Reimann

Frank Reimann

University of Cambridge

Publications: 22

Dale E. Bredesen

Dale E. Bredesen

University of California, Los Angeles

Publications: 22

Carsten Culmsee

Carsten Culmsee

Philipp University of Marburg

Publications: 22

Eliezer Masliah

Eliezer Masliah

National Institutes of Health

Publications: 20

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