D-Index & Metrics Best Publications
Biology and Biochemistry
South Korea
2023

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 57 Citations 10,961 206 World Ranking 9415 National Ranking 89

Research.com Recognitions

Awards & Achievements

2023 - Research.com Biology and Biochemistry in South Korea Leader Award

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Internal medicine

His main research concerns Internal medicine, Endocrinology, Neural stem cell, Cell biology and Neurogenesis. His research on Internal medicine frequently connects to adjacent areas such as Mitochondrion. His Endocrinology study frequently links to adjacent areas such as Constitutive androstane receptor.

The concepts of his Neural stem cell study are interwoven with issues in Hippocampal formation, AMPK and Resveratrol. He combines subjects such as Apoptosis and Cell culture with his study of Cell biology. His Neurogenesis study combines topics in areas such as Dentate gyrus, Hippocampus and Brain-derived neurotrophic factor.

His most cited work include:

  • Evidence that brain-derived neurotrophic factor is required for basal neurogenesis and mediates, in part, the enhancement of neurogenesis by dietary restriction in the hippocampus of adult mice (760 citations)
  • Folic acid deficiency and homocysteine impair DNA repair in hippocampal neurons and sensitize them to amyloid toxicity in experimental models of Alzheimer's disease. (547 citations)
  • Dietary restriction enhances neurotrophin expression and neurogenesis in the hippocampus of adult mice (352 citations)

What are the main themes of his work throughout his whole career to date?

His primary scientific interests are in Internal medicine, Endocrinology, Cell biology, Hippocampal formation and Oxidative stress. His Internal medicine study incorporates themes from Immunology and MAPK/ERK pathway. His study in Endocrinology is interdisciplinary in nature, drawing from both Neurotrophic factors and Phthalate.

Jaewon Lee interconnects Apoptosis and Biochemistry in the investigation of issues within Cell biology. His Hippocampal formation research is multidisciplinary, incorporating perspectives in Glutamate receptor, Neuroprotection, Neurogenesis, Hippocampus and Neural stem cell. The study incorporates disciplines such as Dentate gyrus and Brain-derived neurotrophic factor in addition to Neurogenesis.

He most often published in these fields:

  • Internal medicine (26.29%)
  • Endocrinology (25.90%)
  • Cell biology (15.14%)

What were the highlights of his more recent work (between 2016-2021)?

  • Pharmacology (11.95%)
  • Neuroinflammation (5.58%)
  • Neuroscience (10.76%)

In recent papers he was focusing on the following fields of study:

Jaewon Lee mostly deals with Pharmacology, Neuroinflammation, Neuroscience, Neuroprotection and Nephrotoxicity. His Pharmacology course of study focuses on Oxidative stress and Cell biology, Metabolome and Taurine. The Neuroscience study combines topics in areas such as Chemokine and Disease.

His research on Neuroprotection also deals with topics like

  • MPTP and related Nigrostriatal pathway,
  • Parkinson's disease which intersects with area such as Brain damage. The subject of his Inflammation research is within the realm of Internal medicine. His studies in Reactive oxygen species integrate themes in fields like Hippocampal formation, Neurogenesis and Neural stem cell.

Between 2016 and 2021, his most popular works were:

  • Redefining Chronic Inflammation in Aging and Age-Related Diseases: Proposal of the Senoinflammation Concept. (96 citations)
  • Curcumin ameliorates cadmium-induced nephrotoxicity in Sprague-Dawley rats. (39 citations)
  • Significant roles of neuroinflammation in Parkinson's disease: therapeutic targets for PD prevention. (30 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Internal medicine

Jaewon Lee mainly focuses on Neuroscience, Pharmacology, Neuroinflammation, Parkinson's disease and Chemokine. The various areas that Jaewon Lee examines in his Neuroscience study include Neurotoxicity and Learning memory. Jaewon Lee works mostly in the field of Parkinson's disease, limiting it down to topics relating to Neuroprotection and, in certain cases, Dopaminergic, Neurodegeneration, MPTP, Mitochondrion and Oxidative stress, as a part of the same area of interest.

His research in Anti-inflammatory intersects with topics in Endocrinology and Internal medicine. His Hippocampal formation study in the realm of Endocrinology interacts with subjects such as Brominated flame retardant. His Internal medicine study typically links adjacent topics like Neural stem cell.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Folic acid deficiency and homocysteine impair DNA repair in hippocampal neurons and sensitize them to amyloid toxicity in experimental models of Alzheimer's disease.

Inna I. Kruman;T. S. Kumaravel;Althaf Lohani;Ward A. Pedersen.
The Journal of Neuroscience (2002)

862 Citations

Evidence that brain-derived neurotrophic factor is required for basal neurogenesis and mediates, in part, the enhancement of neurogenesis by dietary restriction in the hippocampus of adult mice

Jaewon Lee;Wenzhen Duan;Mark P. Mattson;Mark P. Mattson;Mark P. Mattson.
Journal of Neurochemistry (2002)

760 Citations

Dietary restriction enhances neurotrophin expression and neurogenesis in the hippocampus of adult mice

Jaewon Lee;Kim B. Seroogy;Mark P. Mattson;Mark P. Mattson;Mark P. Mattson.
Journal of Neurochemistry (2002)

516 Citations

Dietary restriction increases the number of newly generated neural cells, and induces BDNF expression, in the dentate gyrus of rats.

Jaewon Lee;Wenzhen Duan;Jeffrey M. Long;Donald K. Ingram.
Journal of Molecular Neuroscience (2000)

499 Citations

Curcumin Stimulates Proliferation of Embryonic Neural Progenitor Cells and Neurogenesis in the Adult Hippocampus

So Jung Kim;Tae Gen Son;Hee Ra Park;Mikyung Park.
Journal of Biological Chemistry (2008)

340 Citations

A high-fat diet impairs neurogenesis: involvement of lipid peroxidation and brain-derived neurotrophic factor.

Hee Ra Park;Mikyung Park;Jehun Choi;Kun-Young Park.
Neuroscience Letters (2010)

335 Citations

Direct Inhibition of GSK3β by the Phosphorylated Cytoplasmic Domain of LRP6 in Wnt/β-Catenin Signaling

Shunfu Piao;Sun Hye Lee;Hyunjoon Kim;Soohwan Yum.
PLOS ONE (2008)

235 Citations

Suppression of brain aging and neurodegenerative disorders by dietary restriction and environmental enrichment: molecular mechanisms

Mark P. Mattson;Wenzhen Duan;Jaewon Lee;Zhihong Guo.
Mechanisms of Ageing and Development (2001)

221 Citations

Dietary restriction stimulates BDNF production in the brain and thereby protects neurons against excitotoxic injury.

Wenzhen Duan;JaeWon Lee;JaeWon Lee;ZhiHong Guo;Mark P. Mattson;Mark P. Mattson;Mark P. Mattson.
Journal of Molecular Neuroscience (2001)

209 Citations

Molecular Inflammation as an Underlying Mechanism of the Aging Process and Age-related Diseases

H.Y. Chung;E.K. Lee;Y.J. Choi;J.M. Kim.
Journal of Dental Research (2011)

208 Citations

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