Jaewon Lee

Overview

Best Publications

• Folic acid deficiency and homocysteine impair DNA repair in hippocampal neurons and sensitize them to amyloid toxicity in experimental models of Alzheimer's disease.

  Inna I. Kruman;T. S. Kumaravel;Althaf Lohani;Ward A. Pedersen

  900
  Citations

• Evidence that brain-derived neurotrophic factor is required for basal neurogenesis and mediates, in part, the enhancement of neurogenesis by dietary restriction in the hippocampus of adult mice

  Jaewon Lee;Wenzhen Duan;Mark P. Mattson;Mark P. Mattson;Mark P. Mattson

  900
  Citations

• Dietary restriction enhances neurotrophin expression and neurogenesis in the hippocampus of adult mice

  Jaewon Lee;Kim B. Seroogy;Mark P. Mattson;Mark P. Mattson;Mark P. Mattson

  562
  Citations

• Dietary restriction increases the number of newly generated neural cells, and induces BDNF expression, in the dentate gyrus of rats.

  Jaewon Lee;Wenzhen Duan;Jeffrey M. Long;Donald K. Ingram

  518
  Citations

• Redefining Chronic Inflammation in Aging and Age-Related Diseases: Proposal of the Senoinflammation Concept.

  Hae Young Chung;Dae Hyun Kim;Eun Kyeong Lee;Ki Wung Chung

  428
  Citations

• A high-fat diet impairs neurogenesis: involvement of lipid peroxidation and brain-derived neurotrophic factor.

  Hee Ra Park;Mikyung Park;Jehun Choi;Kun-Young Park

  417
  Citations

• Curcumin Stimulates Proliferation of Embryonic Neural Progenitor Cells and Neurogenesis in the Adult Hippocampus

  So Jung Kim;Tae Gen Son;Hee Ra Park;Mikyung Park

  409
  Citations

• Adenylyl cyclase-associated protein 1 is a receptor for human resistin and mediates inflammatory actions of human monocytes.

  Sahmin Lee;Sahmin Lee;Hyun Chae Lee;Yoo Wook Kwon;Sang Eun Lee

  282
  Citations

• Direct Inhibition of GSK3β by the Phosphorylated Cytoplasmic Domain of LRP6 in Wnt/β-Catenin Signaling

  Shunfu Piao;Sun Hye Lee;Hyunjoon Kim;Soohwan Yum

  264
  Citations

• Molecular Inflammation as an Underlying Mechanism of the Aging Process and Age-related Diseases

  H.Y. Chung;E.K. Lee;Y.J. Choi;J.M. Kim

  259
  Citations

• Suppression of brain aging and neurodegenerative disorders by dietary restriction and environmental enrichment: molecular mechanisms

  Mark P. Mattson;Wenzhen Duan;Jaewon Lee;Zhihong Guo

  232
  Citations

• Dietary restriction stimulates BDNF production in the brain and thereby protects neurons against excitotoxic injury.

  Wenzhen Duan;JaeWon Lee;JaeWon Lee;ZhiHong Guo;Mark P. Mattson;Mark P. Mattson;Mark P. Mattson

  228
  Citations

• 2-Deoxy-D-glucose protects hippocampal neurons against excitotoxic and oxidative injury: evidence for the involvement of stress proteins.

  Jaewon Lee;Annadora J. Bruce-Keller;Yuri Kruman;Sic L. Chan

  209
  Citations

• Neuroprotective and neurorestorative signal transduction mechanisms in brain aging: Modification by genes, diet and behavior

  Mark P Mattson;Mark P Mattson;Wenzhen Duan;Sic L Chan;Aiwu Cheng

  163
  Citations

• Sirtinol, a class III HDAC inhibitor, induces apoptotic and autophagic cell death in MCF-7 human breast cancer cells

  Jing Wang;Tae Hyung Kim;Mee Young Ahn;Jaewon Lee

  158
  Citations

• Adaptive Cellular Stress Pathways as Therapeutic Targets of Dietary Phytochemicals: Focus on the Nervous System

  Jaewon Lee;Dong Gyu Jo;Daeui Park;Hae Young Chung

  154
  Citations

• Herp stabilizes neuronal Ca2+ homeostasis and mitochondrial function during endoplasmic reticulum stress.

  Sic L. Chan;Weiming Fu;Peisu Zhang;Aiwu Cheng

  152
  Citations

• Molecular mechanism of SAHA on regulation of autophagic cell death in tamoxifen-resistant MCF-7 breast cancer cells.

  Young Ju Lee;A Jin Won;Jaewon Lee;Jee H. Jung

  147
  Citations

• Baicalein attenuates impaired hippocampal neurogenesis and the neurocognitive deficits induced by γ-ray radiation

  Shin Bi Oh;Hee Ra Park;Young Jung Jang;Seon Young Choi

  141
  Citations

• Suppression of age-related inflammatory NF-κB activation by cinnamaldehyde

  Dae Hyun Kim;Chul Hong Kim;Min-Sun Kim;Ji Young Kim

  141
  Citations