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Bryan T. Hennessy

Bryan T. Hennessy

D-Index & Metrics

Medicine

D-Index
77
Citations
37558
World Ranking
18247
National Ranking
50

Overview

Bryan T. Hennessy is affiliated with Beaumont Hospital in Ireland. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology. The work extensively covers subfields such as Oncology, Pulmonary and Respiratory Medicine, Cancer Research, Molecular Biology, and Pathology and Forensic Medicine.

The scientist's publications reflect significant contributions to cancer research and treatment, as well as respiratory and molecular biology studies. Key topics in their research include:

  • HER2/EGFR in Cancer Research
  • Cancer Treatment and Pharmacology
  • Cancer Genomics and Diagnostics
  • Advanced Breast Cancer Therapies
  • Breast Cancer Treatment Studies
  • Lung Cancer Treatments and Mutations
  • Chronic Lymphocytic Leukemia Research

Frequent publication venues for Bryan T. Hennessy's work are:

  • Journal of Clinical Oncology
  • Irish Journal of Medical Science (1971 -)
  • Cancer Research
  • Annals of Oncology
  • Neurology

Their recent notable papers include:

  • "Response to Neoadjuvant Therapy and Long-Term Survival in Patients With Triple-Negative Breast Cancer" (2023), Journal of Clinical Oncology
  • "Ponesimod Compared With Teriflunomide in Patients With Relapsing Multiple Sclerosis in the Active-Comparator Phase 3 OPTIMUM Study" (2021), JAMA Neurology
  • "Use of exhaled breath condensate (EBC) in the diagnosis of SARS-COV-2 (COVID-19)" (2020), Thorax
  • "Effects of HER Family-targeting Tyrosine Kinase Inhibitors on Antibody-dependent Cell-mediated Cytotoxicity in HER2-expressing Breast Cancer" (2020), Clinical Cancer Research
  • "BRCA1 Promoter Methylation and Clinical Outcomes in Ovarian Cancer: An Individual Patient Data Meta-Analysis" (2020), JNCI Journal of the National Cancer Institute

Hennessy's collaborative work includes frequent co-authors such as:

  • Patrick G. Morris
  • Sinéad Toomey
  • Oscar S. Breathnach
  • Liam Grogan
  • John Crown

Best Publications

  • Response to Neoadjuvant Therapy and Long-Term Survival in Patients With Triple-Negative Breast Cancer

    Cornelia Liedtke;Chafika Mazouni;Kenneth R. Hess;Fabrice André

  • Exploiting the PI3K/AKT Pathway for Cancer Drug Discovery

    Bryan T. Hennessy;Debra L. Smith;Prahlad T. Ram;Yiling Lu

  • A functional genetic approach identifies the PI3K pathway as a major determinant of trastuzumab resistance in breast cancer.

    Katrien Berns;Hugo M. Horlings;Bryan T. Hennessy;Mandy Madiredjo

  • The biology of ovarian cancer: new opportunities for translation

    Robert C. Bast;Bryan Hennessy;Gordon B. Mills

  • Measurement of Residual Breast Cancer Burden to Predict Survival After Neoadjuvant Chemotherapy

    W. Fraser Symmans;Florentia Peintinger;Christos Hatzis;Radhika Rajan

  • An integrative genomic and proteomic analysis of PIK3CA, PTEN, and AKT mutations in breast cancer.

    Katherine Stemke-Hale;Ana Maria Gonzalez-Angulo;Ana Lluch;Richard M. Neve

  • Characterization of a naturally occurring breast cancer subset enriched in epithelial-to-mesenchymal transition and stem cell characteristics.

    Bryan T. Hennessy;Ana Maria Gonzalez-Angulo;Katherine Stemke-Hale;Michael Z. Gilcrease

  • The Energy Sensing LKB1-AMPK Pathway Regulates p27kip1 Phosphorylation Mediating the Decision to Enter Autophagy or Apoptosis

    Jiyong Liang;Shan H. Shao;Shan H. Shao;Zhi Xiang Xu;Bryan Hennessy

  • Homologous Recombination Deficiency (HRD) Score Predicts Response to Platinum-Containing Neoadjuvant Chemotherapy in Patients with Triple-Negative Breast Cancer.

    Melinda L. Telli;Kirsten M. Timms;Julia Reid;Bryan Hennessy

  • Reverse phase protein array: validation of a novel proteomic technology and utility for analysis of primary leukemia specimens and hematopoietic stem cells

    Raoul Tibes;Yi Hua Qiu;Yiling Lu;Bryan Hennessy

  • Patterns of genomic loss of heterozygosity predict homologous recombination repair defects in epithelial ovarian cancer

    Victor Abkevich;Kirsten Timms;Bryan T. Hennessy;Jennifer Potter

  • Incidence and Outcome of BRCA Mutations in Unselected Patients with Triple Receptor-Negative Breast Cancer

    Ana M. Gonzalez-Angulo;Kirsten M. Timms;Shuying Liu;Huiqin Chen

  • Hyperactivation of phosphatidylinositol-3 kinase promotes escape from hormone dependence in estrogen receptor–positive human breast cancer

    Todd W. Miller;Bryan T. Hennessy;Ana M. González-Angulo;Emily M. Fox

  • Next-generation mTOR inhibitors in clinical oncology: how pathway complexity informs therapeutic strategy.

    Seth A. Wander;Bryan T. Hennessy;Joyce M. Slingerland

  • Subtype and pathway specific responses to anticancer compounds in breast cancer.

    Laura M. Heiser;Anguraj Sadanandam;Wen-Lin Kuo;Stephen C. Benz

  • Correlating transcriptional networks to breast cancer survival: a large-scale coexpression analysis

    Colin Clarke;Stephen F. Madden;Padraig Doolan;Sinead T. Aherne

  • Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer.

    Suzanne A. Eccles;Eric O. Aboagye;Simak Ali;Annie S. Anderson

  • High Frequency of PIK3R1 and PIK3R2 Mutations in Endometrial Cancer Elucidates a Novel Mechanism for Regulation of PTEN Protein Stability

    Lydia W.T. Cheung;Bryan T. Hennessy;Bryan T. Hennessy;Jie Li;Shuangxing Yu

  • Outcome After Pathologic Complete Eradication of Cytologically Proven Breast Cancer Axillary Node Metastases Following Primary Chemotherapy

    Bryan T. Hennessy;Gabriel N. Hortobagyi;Roman Rouzier;Henry Kuerer

  • Somatic Mutations in BRCA1 and BRCA2 Could Expand the Number of Patients That Benefit From Poly (ADP Ribose) Polymerase Inhibitors in Ovarian Cancer

    Bryan T.J. Hennessy;Kirsten M. Timms;Mark S. Carey;Alexander Gutin

Frequent Co-Authors

Gordon B. Mills
Gordon B. Mills Oregon Health & Science University
Ana M. Gonzalez-Angulo
Ana M. Gonzalez-Angulo The University of Texas MD Anderson Cancer Center
John Crown
John Crown Dublin City University
Yiling Lu
Yiling Lu The University of Texas MD Anderson Cancer Center
Jochen H. M. Prehn
Jochen H. M. Prehn Royal College of Surgeons in Ireland
Gabriel N. Hortobagyi
Gabriel N. Hortobagyi The University of Texas MD Anderson Cancer Center
Vicente Valero
Vicente Valero The University of Texas MD Anderson Cancer Center
Kenneth J. O'Byrne
Kenneth J. O'Byrne Queensland University of Technology
Karen H. Lu
Karen H. Lu The University of Texas MD Anderson Cancer Center
Ana Lluch
Ana Lluch University of Valencia

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