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Medicine

D-Index
97
Citations
48642
World Ranking
9104
National Ranking
4695

Overview

Ana M. Gonzalez-Angulo is affiliated with The University of Texas MD Anderson Cancer Center in the United States. Their research primarily focuses on the biochemistry, genetics, and molecular biology fields, with significant contributions to medicine. Their work encompasses specialized subfields including cancer research, oncology, molecular biology, pulmonary and respiratory medicine, and pharmacology.

Their research addresses key topics such as HER2/EGFR in cancer research, breast cancer treatment studies, cancer treatment and pharmacology, cancer related to hypoxia and metabolism, metabolism in diabetes and cancer, cancer, lipids and metabolism, and cancer genomics and diagnostics.

Among their recent publications are:

  • Response to Neoadjuvant Therapy and Long-Term Survival in Patients With Triple-Negative Breast Cancer (2023, Journal of Clinical Oncology)
  • Oxidative Phosphorylation Is a Metabolic Vulnerability in Chemotherapy-Resistant Triple-Negative Breast Cancer (2021, Cancer Research)
  • Endocrine-Therapy-Resistant ESR1 Variants Revealed by Genomic Characterization of Breast-Cancer-Derived Xenografts (2020, UNC Libraries)
  • Genomic, Transcriptomic, and Proteomic Profiling of Metastatic Breast Cancer (2021, Clinical Cancer Research)
  • ADAMs contribute to triple negative breast cancer via mTORC1 pathway: targeting ADAM-mTOR axis improves efficacy (2025, Cancer Letters)

Frequent coauthors in collaboration with Ana M. Gonzalez-Angulo include:

  • Gordon B. Mills
  • Gabriel N. Hortobágyi
  • Argun Akçakanat
  • Funda Meric-Bernstam
  • Charles M. Perou

Their work appears regularly in a range of publication venues, such as:

  • UNC Libraries
  • Journal of Clinical Oncology
  • Cancer Research
  • Clinical Cancer Research
  • Cancer Letters

Best Publications

  • Comprehensive molecular portraits of human breast tumours

    Daniel C. Koboldt;Robert S. Fulton;Michael D. McLellan;Heather Schmidt

  • A functional genetic approach identifies the PI3K pathway as a major determinant of trastuzumab resistance in breast cancer.

    Katrien Berns;Hugo M. Horlings;Bryan T. Hennessy;Mandy Madiredjo

  • An integrative genomic and proteomic analysis of PIK3CA, PTEN, and AKT mutations in breast cancer.

    Katherine Stemke-Hale;Ana Maria Gonzalez-Angulo;Ana Lluch;Richard M. Neve

  • Overview of Resistance to Systemic Therapy in Patients with Breast Cancer

    Ana Maria Gonzalez-Angulo;Flavia Morales-Vasquez;Gabriel N. Hortobagyi

  • Metformin and Pathologic Complete Responses to Neoadjuvant Chemotherapy in Diabetic Patients With Breast Cancer

    Sao Jiralerspong;Shana L. Palla;Sharon Hermes Giordano;Funda Meric-Bernstam

  • Characterization of a naturally occurring breast cancer subset enriched in epithelial-to-mesenchymal transition and stem cell characteristics.

    Bryan T. Hennessy;Ana Maria Gonzalez-Angulo;Katherine Stemke-Hale;Michael Z. Gilcrease

  • Differential response to neoadjuvant chemotherapy among 7 triple-negative breast cancer molecular subtypes

    Hiroko Masuda;Keith A. Baggerly;Ying Wang;Ya Zhang

  • Targeting the mTOR Signaling Network for Cancer Therapy

    Funda Meric-Bernstam;Ana Maria Gonzalez-Angulo

  • Clinical and Pathologic Characteristics of Patients With BRCA-Positive and BRCA-Negative Breast Cancer

    Deann P. Atchley;Constance T. Albarracin;Adriana Lopez;Vicente Valero

  • Endocrine-therapy-resistant ESR1 variants revealed by genomic characterization of breast-cancer-derived xenografts.

    Shunqiang Li;Dong Shen;Jieya Shao;Robert Crowder

  • Incidence and Outcome of BRCA Mutations in Unselected Patients with Triple Receptor-Negative Breast Cancer

    Ana M. Gonzalez-Angulo;Kirsten M. Timms;Shuying Liu;Huiqin Chen

  • Emergence of constitutively active estrogen receptor-α mutations in pretreated advanced estrogen receptor positive breast cancer

    Rinath Jeselsohn;Roman Yelensky;Gilles Buchwalter;Gilles Buchwalter;Garrett Frampton

  • Hyperactivation of phosphatidylinositol-3 kinase promotes escape from hormone dependence in estrogen receptor–positive human breast cancer

    Todd W. Miller;Bryan T. Hennessy;Ana M. González-Angulo;Emily M. Fox

  • AKT-Independent Signaling Downstream of Oncogenic PIK3CA Mutations in Human Cancer

    Krishna M. Vasudevan;David A. Barbie;David A. Barbie;Michael A. Davies;Rosalia Rabinovsky

  • Beta-Blocker Use Is Associated With Improved Relapse-Free Survival in Patients With Triple-Negative Breast Cancer

    Amal Melhem-Bertrandt;Mariana Chavez-MacGregor;Xiudong Lei;Erika N. Brown

  • Perivascular M2 Macrophages Stimulate Tumor Relapse after Chemotherapy

    Russell Hughes;Bin-Zhi Qian;Charlotte Rowan;Munitta Muthana

  • Long-Term Cardiac Tolerability of Trastuzumab in Metastatic Breast Cancer: The M.D. Anderson Cancer Center Experience

    Valentina Guarneri;Daniel J. Lenihan;Vicente Valero;Jean Bernard Durand

  • Loss of Human Epidermal Growth Factor Receptor 2 (HER2) Expression in Metastatic Sites of HER2-Overexpressing Primary Breast Tumors

    Naoki Niikura;Jun Liu;Naoki Hayashi;Elizabeth Ann Mittendorf

  • Invasive Lobular Carcinoma Classic Type: Response to Primary Chemotherapy and Survival Outcomes

    Massimo Cristofanilli;Ana Gonzalez-Angulo;Nour Sneige;Shu Wan Kau

  • Use of Biomarkers to Guide Decisions on Systemic Therapy for Women With Metastatic Breast Cancer: American Society of Clinical Oncology Clinical Practice Guideline

    Catherine Van Poznak;Mark R. Somerfield;Robert C. Bast;Massimo Cristofanilli

Frequent Co-Authors

Gabriel N. Hortobagyi
Gabriel N. Hortobagyi The University of Texas MD Anderson Cancer Center
Funda Meric-Bernstam
Funda Meric-Bernstam The University of Texas MD Anderson Cancer Center
Gordon B. Mills
Gordon B. Mills Oregon Health & Science University
Vicente Valero
Vicente Valero The University of Texas MD Anderson Cancer Center
Aysegul A. Sahin
Aysegul A. Sahin The University of Texas MD Anderson Cancer Center
Bryan T. Hennessy
Bryan T. Hennessy Beaumont Hospital
Thomas A. Buchholz
Thomas A. Buchholz The University of Texas MD Anderson Cancer Center
Naoto T. Ueno
Naoto T. Ueno University of Hawaiʻi Cancer Center
Massimo Cristofanilli
Massimo Cristofanilli Cornell University
Elizabeth A. Mittendorf
Elizabeth A. Mittendorf Brigham and Women's Hospital

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