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Biology and Biochemistry

D-Index
66
Citations
23872
World Ranking
8473
National Ranking
72

Overview

Keiryn L. Bennett is a researcher affiliated with the Medical University of Vienna in Austria. Their academic work spans several fields within the life sciences, with a focus on molecular biology and physiology as subfields, alongside contributions in epidemiology, genetics, and neurology.

Their main areas of study include biochemistry, genetics, and molecular biology, complemented by medical research. Bennett's research topics cover mitochondrial function and pathology, ATP synthase and ATPases, Alzheimer's disease research and treatments, autophagy in disease and therapy, genetics and neurodevelopmental disorders, bioinformatics and genomic networks, and neuroinflammation and neurodegeneration mechanisms.

The scientist has published several papers exploring mitochondrial dynamics and neurodegenerative conditions. Notable recent publications include:

  • "<scp>TMBIM5</scp> is the Ca 2+ /H + antiporter of mammalian mitochondria," 2022, EMBO Reports
  • "MICS1 is the Ca2+/H+ antiporter of mammalian mitochondria," 2021, bioRxiv (Cold Spring Harbor Laboratory)
  • "Modelling AD-relevant pathophysiology in neurons, astrocytes and microglia from two complete sets of isogenic iPSC lines generated by the ADAPTED project," 2020, Alzheimer s & Dementia
  • "Cross-omics studies of the role of apolipoprotein E in Alzheimer's disease and dementia: Searching common pathways in patients, populations and cellular models," 2020, Alzheimer s & Dementia
  • "MICS1/TIMBIM5, but not LETM1, is the mitochondrial Ca2+/H+ exchanger," 2022, Biochimica et Biophysica Acta (BBA) - Bioenergetics

Bennett frequently collaborates with a number of co-authors, among whom are Shane Austin, Ronald Mekis, Sami E.M. Mohammed, Mariafrancesca Scalise, and Michele Galluccio. Each has co-authored multiple publications with Bennett, indicating ongoing collaborative research efforts.

The venues in which Bennett publishes include Alzheimer s & Dementia, EMBO Reports, bioRxiv (Cold Spring Harbor Laboratory), Biochimica et Biophysica Acta (BBA) - Bioenergetics, and the Journal of Veterinary Pharmacology and Therapeutics. This range demonstrates a multidisciplinary approach covering both fundamental molecular studies and applications to neurological diseases.

Best Publications

  • Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry

    Yuen Ho;Albrecht Gruhler;Adrian Heilbut;Gary D Bader;Gary D Bader

  • The CRAPome: a contaminant repository for affinity purification–mass spectrometry data

    Dattatreya Mellacheruvu;Zachary Wright;Amber L. Couzens;Jean Philippe Lambert

  • An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome

    Tilmann Bürckstümmer;Christoph Baumann;Stephan Blüml;Stephan Blüml;Evelyn Dixit

  • Gene essentiality and synthetic lethality in haploid human cells

    Vincent A. Blomen;Peter Májek;Lucas T. Jae;Johannes W. Bigenzahn

  • Chemical proteomic profiles of the BCR-ABL inhibitors imatinib, nilotinib, and dasatinib reveal novel kinase and nonkinase targets

    Uwe Rix;Oliver Hantschel;Gerhard Dürnberger;Lily L. Remsing Rix

  • SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1

    Manuele Rebsamen;Lorena Pochini;Taras Stasyk;Mariana E. G. de Araújo

  • RNase P without RNA: Identification and Functional Reconstitution of the Human Mitochondrial tRNA Processing Enzyme

    Johann Holzmann;Peter Frank;Esther Löffler;Keiryn L. Bennett

  • Complement factor H binds malondialdehyde epitopes and protects from oxidative stress

    David Weismann;Karsten Hartvigsen;Karsten Hartvigsen;Karsten Hartvigsen;Nadine Lauer;Keiryn L. Bennett

  • IFIT1 is an antiviral protein that recognizes 5′-triphosphate RNA

    Andreas Pichlmair;Caroline Lassnig;Carol-Ann Eberle;Maria W Górna

  • An efficient tandem affinity purification procedure for interaction proteomics in mammalian cells

    Tilmann Bürckstümmer;Keiryn L Bennett;Adrijana Preradovic;Gregor Schütze

  • Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy

    Kilian V. M. Huber;Eidarus Salah;Branka Radic;Manuela Gridling

  • Artemisinins Target GABAA Receptor Signaling and Impair α Cell Identity

    Jin Li;Tamara Casteels;Thomas Frogne;Camilla Ingvorsen

  • The DEAD-box helicase DDX3X is a critical component of the TANK-binding kinase 1-dependent innate immune response

    Didier Soulat;Tilmann Bürckstümmer;Sandra Westermayer;Adriana Goncalves

  • The Btk tyrosine kinase is a major target of the Bcr-Abl inhibitor dasatinib

    Oliver Hantschel;Uwe Rix;Uwe Schmidt;Tilmann Bürckstümmer

  • Global target profile of the kinase inhibitor bosutinib in primary chronic myeloid leukemia cells

    L L Remsing Rix;U Rix;J Colinge;O Hantschel

  • A chemical and phosphoproteomic characterization of dasatinib action in lung cancer.

    Jiannong Li;Uwe Rix;Bin Fang;Yun Bai

  • Viral immune modulators perturb the human molecular network by common and unique strategies

    Andreas Pichlmair;Kumaran Kandasamy;Gualtiero Alvisi;Orla Mulhern

  • CD14 is a coreceptor of Toll-like receptors 7 and 9

    Christoph L. Baumann;Irene M. Aspalter;Omar Sharif;Andreas Pichlmair

  • Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia

    Florian Grebien;Masoud Vedadi;Masoud Vedadi;Matthäus Getlik;Roberto Giambruno

  • The DEAD-box helicase DDX3X is a critical component of the TANK-binding kinase 1-dependent innate immune response This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits distribution, and reproduction in any medium, provided the original author and source are credited. This license does not permit commercial exploitation or the creation of derivative works without specific permission.

    Didier Soulat;Sandra Westermayer;Adriana Goncalves;Angela Bauch

Frequent Co-Authors

Giulio Superti-Furga
Giulio Superti-Furga Medical University of Vienna
Jacques Colinge
Jacques Colinge University of Montpellier
Christoph Bock
Christoph Bock Austrian Academy of Sciences
Peter Valent
Peter Valent Medical University of Vienna
Sylvia Knapp
Sylvia Knapp Medical University of Vienna
Johannes Zuber
Johannes Zuber Research Institute of Molecular Pathology
Matthias Mann
Matthias Mann Max Planck Institute of Biochemistry
Gert Lubec
Gert Lubec Paracelsus Medical University
Eric B. Haura
Eric B. Haura University of South Florida
Thijn R. Brummelkamp
Thijn R. Brummelkamp Antoni van Leeuwenhoek Hospital

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