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Molecular Biology
Canada
2026

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Best Female Scientists

D-Index
116
Citations
61995
World Ranking
668
National Ranking
21

Molecular Biology

D-Index
119
Citations
64324
World Ranking
263
National Ranking
7

Research.com Recognitions

  • 2026 - Research.com Molecular Biology in Canada Leader Award
  • 2025 - Research.com Best Female Scientists Award
  • 2025 - Research.com Molecular Biology in Canada Leader Award
  • 2023 - Research.com Molecular Biology in Canada Leader Award
  • 2015 - Fellow of the Royal Society of Canada Academy of Science

Overview

Anne-Claude Gingras is affiliated with the Lunenfeld-Tanenbaum Research Institute in Canada. Their research spans several fields, predominantly Medicine and Biochemistry, Genetics, and Molecular Biology, with a strong focus on infectious diseases and molecular biology.

The scientist's work covers a range of subfields including Infectious Diseases, Molecular Biology, Cell Biology, Immunology, and Oncology. Their research topics highlight contributions to understanding SARS-CoV-2 and COVID-19, COVID-19 clinical research studies, detection and testing for SARS-CoV-2, biotin-related studies, cellular transport and secretion, RNA and protein synthesis mechanisms, and CRISPR and genetic engineering.

Notable recent papers authored by Anne-Claude Gingras include:

  • Persistence of serum and saliva antibody responses to SARS-CoV-2 spike antigens in COVID-19 patients, 2020, Science Immunology
  • A proximity-dependent biotinylation map of a human cell, 2021, Nature
  • Robust, reproducible and quantitative analysis of thousands of proteomes by micro-flow LC-MS/MS, 2020, Nature Communications
  • Rare driver mutations in head and neck squamous cell carcinomas converge on NOTCH signaling, 2020, Science
  • Systemic and mucosal IgA responses are variably induced in response to SARS-CoV-2 mRNA vaccination and are associated with protection against subsequent infection, 2022, Mucosal Immunology

Anne-Claude Gingras has frequently published in the following scientific venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Molecular Cell
  • The Journal of Immunology
  • SSRN Electronic Journal

Collaborations have been an important aspect of their career, with frequent coauthors including:

  • Karen Colwill (81 joint publications)
  • Allison McGeer (52 joint publications)
  • Kento T. Abe (46 joint publications)
  • Cassandra J. Wong (43 joint publications)
  • Bhavisha Rathod (35 joint publications)

In recognition of their contributions to science, Anne-Claude Gingras was awarded the title of Fellow of the Royal Society of Canada in 2015 by the Academy of Science.

Best Publications

  • eIF4 Initiation Factors: Effectors of mRNA Recruitment to Ribosomes and Regulators of Translation

    Anne-Claude Gingras;Brian Raught;Nahum Sonenberg

  • The genetic landscape of a cell.

    Michael Costanzo;Anastasia Baryshnikova;Jeremy Bellay;Yungil Kim

  • The CRAPome: a contaminant repository for affinity purification–mass spectrometry data

    Dattatreya Mellacheruvu;Zachary Wright;Amber L. Couzens;Jean Philippe Lambert

  • Regulation of translation initiation by FRAP/mTOR

    Anne-Claude Gingras;Brian Raught;Nahum Sonenberg

  • Histone recognition and large-scale structural analysis of the human bromodomain family.

    Panagis Filippakopoulos;Sarah Picaud;Maria Mangos;Tracy Keates

  • Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism

    Anne-Claude Gingras;Steven P. Gygi;Brian Raught;Roberto D. Polakiewicz

  • Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5'-cap function

    Arnim Pause;Graham J. Belsham;Anne Claude Gingras;Olivier Donzé

  • A global genetic interaction network maps a wiring diagram of cellular function

    Michael Costanzo;Benjamin VanderSluis;Elizabeth N. Koch;Anastasia Baryshnikova

  • 4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt(PKB) signaling pathway

    Anne Claude Gingras;Scott G. Kennedy;Maura A. O'Leary;Nahum Sonenberg

  • Hierarchical phosphorylation of the translation inhibitor 4E-BP1

    Anne-Claude Gingras;Brian Raught;Steven P. Gygi;Steven P. Gygi;Anna Niedzwiecka

  • The mRNA 5' cap-binding protein eIF4E and control of cell growth.

    Nahum Sonenberg;Anne-Claude Gingras

  • Analysis of protein complexes using mass spectrometry

    Anne-Claude Gingras;Anne-Claude Gingras;Matthias Gstaiger;Brian Raught;Brian Raught;Ruedi Aebersold

  • Rapamycin blocks the phosphorylation of 4E-BP1 and inhibits cap-dependent initiation of translation.

    Laura Beretta;Anne Claude Gingras;Yuri V. Svitkin;Michael N. Hall

  • A rapamycin-sensitive signaling pathway contributes to long-term synaptic plasticity in the hippocampus

    Shao Jun Tang;Gerald Reis;Hyejin Kang;Anne Claude Gingras

  • Persistence of serum and saliva antibody responses to SARS-CoV-2 spike antigens in COVID-19 patients.

    Baweleta Isho;Kento T. Abe;Kento T. Abe;Michelle Zuo;Alainna J. Jamal;Alainna J. Jamal

  • Cocrystal Structure of the Messenger RNA 5′ Cap-Binding Protein (eIF4E) Bound to 7-methyl-GDP

    Joseph Marcotrigiano;Anne-Claude Gingras;Nahum Sonenberg;Stephen K. Burley;Stephen K. Burley;Stephen K. Burley

  • Human eukaryotic translation initiation factor 4G (eIF4G) recruits Mnk1 to phosphorylate eIF4E

    Stéphane Pyronnet;Hiroaki Imataka;Anne‐Claude Gingras;Rikiro Fukunaga

  • SAINT: probabilistic scoring of affinity purification-mass spectrometry data

    Hyungwon Choi;Brett Larsen;Zhen Yuan Lin;Ashton Breitkreutz

  • The target of rapamycin (TOR) proteins

    Brian Raught;Anne-Claude Gingras;Nahum Sonenberg

  • A global protein kinase and phosphatase interaction network in yeast.

    Ashton Breitkreutz;Hyungwon Choi;Jeffrey R. Sharom;Lorrie Boucher

Frequent Co-Authors

Nahum Sonenberg
Nahum Sonenberg McGill University
Brian Raught
Brian Raught Princess Margaret Cancer Centre
Frank Sicheri
Frank Sicheri Lunenfeld-Tanenbaum Research Institute
Tony Pawson
Tony Pawson University of Toronto
Laurence Pelletier
Laurence Pelletier Lunenfeld-Tanenbaum Research Institute
Alexey I. Nesvizhskii
Alexey I. Nesvizhskii University of Michigan–Ann Arbor
Daniel Durocher
Daniel Durocher Lunenfeld-Tanenbaum Research Institute
Frederick P. Roth
Frederick P. Roth Lunenfeld-Tanenbaum Research Institute
Mike Tyers
Mike Tyers University of Montreal

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