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Genetics

D-Index
51
Citations
10299
World Ranking
3863
National Ranking
1671

Research.com Recognitions

  • 2011 - Fellow of Alfred P. Sloan Foundation

Overview

Michael M. Desai is affiliated with Harvard University in the United States. Their research primarily spans the fields of biochemistry, genetics, and molecular biology, with a total of 84 publications. Additionally, they have contributed to the field of medicine through 34 publications.

The main subfields of study for their work include genetics, molecular biology, sociology and political science, plant science, and public health, environmental, and occupational health. Their research topics encompass evolution and genetic dynamics, evolutionary game theory and cooperation, genetic diversity and population structure, mathematical and theoretical epidemiology and ecology models, bioinformatics and genomic networks, influenza virus research studies, and monoclonal and polyclonal antibodies research.

Michael M. Desai's recent papers include the following:

  • Compensatory epistasis maintains ACE2 affinity in SARS-CoV-2 Omicron BA.1 (2022, Nature Communications)
  • Phenotypic and molecular evolution across 10,000 generations in laboratory budding yeast populations (2021, eLife)
  • Global epistasis emerges from a generic model of a complex trait (2021, eLife)
  • Epistasis and evolution: recent advances and an outlook for prediction (2023, BMC Biology)
  • Chance and necessity in the pleiotropic consequences of adaptation for budding yeast (2020, Nature Ecology & Evolution)

Frequent coauthors collaborating with Michael M. Desai include:

  • Angela M. Phillips (18 publications)
  • Thomas Dupic (12 publications)
  • Alex N. Nguyen Ba (12 publications)
  • Alief Moulana (11 publications)
  • Milo S. Johnson (10 publications)

The primary venues for their work consist of bioRxiv (Cold Spring Harbor Laboratory) with 25 publications, eLife with 9 publications, Genetics with 4 publications, Nature Communications with 2 publications, and Frontiers in Virology with 2 publications.

Michael M. Desai was awarded the title of Fellow of the Alfred P. Sloan Foundation in 2011.

Best Publications

  • The dynamics of molecular evolution over 60,000 generations

    Benjamin H. Good;Michael J. McDonald;Michael J. McDonald;Jeffrey E. Barrick;Richard E. Lenski

  • Inexpensive Multiplexed Library Preparation for Megabase-Sized Genomes

    Michael Baym;Sergey Kryazhimskiy;Tami D. Lieberman;Hattie Chung

  • Beneficial Mutation-Selection Balance and the Effect of Linkage on Positive Selection

    Michael M. Desai;Daniel S. Fisher

  • Pervasive genetic hitchhiking and clonal interference in forty evolving yeast populations

    Gregory I. Lang;Daniel P. Rice;Mark J. Hickman;Erica Sodergren

  • The repertoire and dynamics of evolutionary adaptations to controlled nutrient-limited environments in yeast.

    David Gresham;Michael M. Desai;Cheryl M. Tucker;Harry T. Jenq

  • Global Epistasis Makes Adaptation Predictable Despite Sequence-Level Stochasticity

    Sergey Kryazhimskiy;Daniel P. Rice;Elizabeth R. Jerison;Michael M. Desai

  • Sex speeds adaptation by altering the dynamics of molecular evolution

    Michael J. McDonald;Daniel P. Rice;Michael M. Desai

  • The speed of evolution and maintenance of variation in asexual populations.

    Michael M. Desai;Daniel S. Fisher;Andrew W. Murray

  • The rate at which asexual populations cross fitness valleys.

    Daniel B. Weissman;Michael M. Desai;Daniel S. Fisher;Marcus W. Feldman

  • Distribution of fixed beneficial mutations and the rate of adaptation in asexual populations

    Benjamin H. Good;Igor M. Rouzine;Daniel J. Balick;Oskar Hallatschek

  • Genetic Variation and the Fate of Beneficial Mutations in Asexual Populations

    Gregory I. Lang;David Botstein;Michael M. Desai

  • The Effect of Strong Purifying Selection on Genetic Diversity.

    Ivana Cvijović;Ivana Cvijović;Benjamin H Good;Benjamin H Good;Michael M Desai;Michael M Desai

  • High-resolution lineage tracking reveals travelling wave of adaptation in laboratory yeast

    Alex N. Nguyen Ba;Ivana Cvijović;José I. Rojas Echenique;Katherine R. Lawrence;Katherine R. Lawrence

  • Clonal Interference, Multiple Mutations, and Adaptation in Large Asexual Populations

    Craig A. Fogle;James L. Nagle;Michael M. Desai

  • Fate of a mutation in a fluctuating environment.

    Ivana Cvijovic;Benjamin Harmar Good;Elizabeth Jerison;Michael Manish Desai

  • Genetic Diversity and the Structure of Genealogies in Rapidly Adapting Populations

    Michael Manish Desai;Aleksandra M. Walczak;Daniel S. Fisher

  • Genetic Diversity in the Interference Selection Limit

    Benjamin H. Good;Aleksandra M. Walczak;Richard A. Neher;Michael M. Desai

  • Dynamic mutation-selection balance as an evolutionary attractor

    Sidhartha Goyal;Daniel J. Balick;Elizabeth R. Jerison;Richard A. Neher

  • Ploidy Controls the Success of Mutators and Nature of Mutations during Budding Yeast Evolution

    Dawn A. Thompson;Michael M. Desai;Andrew W. Murray

  • Global epistasis emerges from a generic model of a complex trait

    Gautam Reddy;Michael M Desai

Frequent Co-Authors

Joshua B. Plotkin
Joshua B. Plotkin University of Pennsylvania
Daniel S. Fisher
Daniel S. Fisher Stanford University
Richard A. Neher
Richard A. Neher University of Basel
George M. Church
George M. Church Harvard University
Markus Ralser
Markus Ralser Charité - University Medicine Berlin
Jonathan Dushoff
Jonathan Dushoff McMaster University
Roy Kishony
Roy Kishony Technion – Israel Institute of Technology
Leonid Kruglyak
Leonid Kruglyak University of California, Los Angeles
David Botstein
David Botstein Princeton University
Hunter B. Fraser
Hunter B. Fraser Stanford University

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