H-Index & Metrics Top Publications

H-Index & Metrics

Discipline name H-index Citations Publications World Ranking National Ranking
Genetics and Molecular Biology H-index 151 Citations 206,263 337 World Ranking 61 National Ranking 41

Research.com Recognitions

Awards & Achievements

2013 - Breakthrough Prize in Life Sciences for linkage mapping of Mendelian disease in humans using DNA polymorphisms.

2013 - Warren Alpert Foundation Prize For their seminal contributions to concepts and methods of creating a genetic map in the human, and of positional cloning, leading to the identification of thousands of human disease genes and ushering in the era of human genetics.

2010 - Albany Medical Center Prize in Medicine and Biomedical Research

2006 - Joseph Zubin Award, American Psychopathological Association

2003 - Gruber Prize in Genetics

1998 - Promega Biotechnology Research Award, American Society for Microbiology

1993 - Member of the National Academy of Medicine (NAM)

1989 - William Allan Award, the American Society of Human Genetics

1988 - Genetics Society of America Medal

1987 - Fellow of the American Association for the Advancement of Science (AAAS)

1985 - Fellow of the American Academy of Arts and Sciences

1981 - Member of the National Academy of Sciences

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Enzyme

His primary areas of investigation include Genetics, Gene, Gene expression profiling, Saccharomyces cerevisiae and Computational biology. His studies in Genome, Human genome, Restriction fragment length polymorphism, Gene mapping and Plasmid are all subfields of Genetics research. His Gene expression profiling research incorporates elements of Basal-Like Breast Carcinoma, Cancer research, International Prognostic Index and Bioinformatics.

His Saccharomyces cerevisiae study results in a more complete grasp of Yeast. The Computational biology study combines topics in areas such as Critical Assessment of Function Annotation, Microarray databases and Biological data. His DNA microarray research includes themes of Complementary DNA and Microarray.

His most cited work include:

  • Gene ontology: tool for the unification of biology. The Gene Ontology Consortium. (26033 citations)
  • Cluster analysis and display of genome-wide expression patterns (15022 citations)
  • Molecular portraits of human breast tumours (11695 citations)

What are the main themes of his work throughout his whole career to date?

His scientific interests lie mostly in Genetics, Gene, Saccharomyces cerevisiae, Molecular biology and Biochemistry. His research on Genetics often connects related areas such as Computational biology. Many of his studies on Gene apply to DNA as well.

His Saccharomyces cerevisiae study is associated with Yeast. His work investigates the relationship between Gene expression profiling and topics such as Cancer research that intersect with problems in Immunology. His Cell biology research focuses on subjects like Cytoskeleton, which are linked to Actin.

He most often published in these fields:

  • Genetics (48.89%)
  • Gene (39.03%)
  • Saccharomyces cerevisiae (24.35%)

What were the highlights of his more recent work (between 2004-2021)?

  • Genetics (48.89%)
  • Saccharomyces cerevisiae (24.35%)
  • Gene (39.03%)

In recent papers he was focusing on the following fields of study:

His main research concerns Genetics, Saccharomyces cerevisiae, Gene, Yeast and Biochemistry. His biological study deals with issues like Computational biology, which deal with fields such as Whole genome sequencing. His Saccharomyces cerevisiae research incorporates themes from Natural selection, Mutant, Mitochondrion and Sequence.

His study in Gene expression, DNA microarray, Regulation of gene expression, Gene expression profiling and Phenotype falls under the purview of Gene. His Yeast research is multidisciplinary, relying on both Cell cycle, Trehalose and Auxotrophy. In his research on the topic of Biochemistry, Bacteria and Fructose 1-phosphate is strongly related with Toxicity.

Between 2004 and 2021, his most popular works were:

  • The Gene Ontology project in 2008 (574 citations)
  • Coordination of Growth Rate, Cell Cycle, Stress Response, and Metabolic Activity in Yeast (462 citations)
  • Pervasive genetic hitchhiking and clonal interference in forty evolving yeast populations (433 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Enzyme

David Botstein mostly deals with Genetics, Saccharomyces cerevisiae, Gene, Biochemistry and Yeast. His study in Mutation, DNA microarray, Genome, Experimental evolution and Phenotype is carried out as part of his Genetics studies. David Botstein has researched Saccharomyces cerevisiae in several fields, including Biological network, Computational biology and Function.

His Gene study focuses mostly on Gene expression, Gene expression profiling, Gene regulatory network and Regulation of gene expression. His work in Gene expression profiling addresses issues such as Bioinformatics, which are connected to fields such as Glioma, Survival rate, Angiogenesis and Cancer research. His Yeast research integrates issues from Urea, Toxicity, Mutant and Ammonia.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Top Publications

Gene ontology: tool for the unification of biology. The Gene Ontology Consortium.

M Ashburner;C A Ball;J A Blake;D Botstein.
Nature Genetics (2000)

28161 Citations

Cluster analysis and display of genome-wide expression patterns

Michael B. Eisen;Paul T. Spellman;Patrick O. Brown;David Botstein.
Proceedings of the National Academy of Sciences of the United States of America (1998)

19747 Citations

Molecular portraits of human breast tumours

Charles M. Perou;Therese Sørlie;Michael B. Eisen;Matt van de Rijn.
Nature (2000)

17727 Citations

Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications

Therese Sørlie;Charles M. Perou;Robert Tibshirani;Turid Aas.
Proceedings of the National Academy of Sciences of the United States of America (2001)

11924 Citations

Construction of a genetic linkage map in man using restriction fragment length polymorphisms.

D Botstein;R L White;M Skolnick;R W Davis.
American Journal of Human Genetics (1980)

11894 Citations

Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling

Ash A. Alizadeh;Michael B. Eisen;R. Eric Davis;Izidore S. Lossos.
Nature (2000)

10864 Citations

MAPPING MENDELIAN FACTORS UNDERLYING QUANTITATIVE TRAITS USING RFLP LINKAGE MAPS

E S Lander;D Botstein.
Genetics (1989)

6358 Citations

Comprehensive Identification of Cell Cycle–regulated Genes of the Yeast Saccharomyces cerevisiae by Microarray Hybridization

Paul T. Spellman;Gavin Sherlock;Gavin Sherlock;Michael Q. Zhang;Vishwanath R. Iyer.
Molecular Biology of the Cell (1998)

6265 Citations

Repeated observation of breast tumor subtypes in independent gene expression data sets

Therese Sørlie;Robert Tibshirani;Joel Parker;Trevor Hastie.
Proceedings of the National Academy of Sciences of the United States of America (2003)

6052 Citations

Genomic expression programs in the response of yeast cells to environmental changes.

Audrey P. Gasch;Paul T. Spellman;Camilla M. Kao;Orna Carmel-Harel.
Molecular Biology of the Cell (2000)

5402 Citations

Profile was last updated on December 6th, 2021.
Research.com Ranking is based on data retrieved from the Microsoft Academic Graph (MAG).
The ranking h-index is inferred from publications deemed to belong to the considered discipline.

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