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Genetics
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2026

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Best Scientists

D-Index
205
Citations
183706
World Ranking
239
National Ranking
159

Genetics

D-Index
204
Citations
182223
World Ranking
21
National Ranking
15

Research.com Recognitions

  • 2026 - Research.com Genetics in United States Leader Award
  • 2025 - Research.com Best Scientists Award
  • 2025 - Research.com Genetics in United States Leader Award
  • 2024 - Research.com Genetics in United States Leader Award
  • 2024 - Research.com Genetics and Molecular Biology in United States Leader Award
  • 2023 - Research.com Genetics in United States Leader Award
  • 2012 - Member of the National Academy of Engineering For contributions to human genome sequencing technologies and DNA synthesis and assembly.
  • 2011 - Member of the National Academy of Sciences
  • 2011 - Benjamin Franklin Medal, Franklin Institute
  • 2009 - Promega Biotechnology Research Award, American Society for Microbiology
  • 1930 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

George M. Church is affiliated with Harvard University in the United States. Their research spans multiple fields within biochemistry, genetics, and molecular biology, contributing to a total of 478 publications in these areas. The primary subfields in their work include molecular biology, genetics, biomedical engineering, infectious diseases, and immunology.

The main research topics addressed by George M. Church include:

  • CRISPR and genetic engineering
  • RNA and protein synthesis mechanisms
  • Advanced biosensing and bioanalysis techniques
  • Pluripotent stem cells research
  • Single-cell and spatial transcriptomics
  • Virus-based gene therapy research
  • Genomics and phylogenetic studies

The scientist has published extensively in several prominent journals, with frequent contributions to:

  • bioRxiv (Cold Spring Harbor Laboratory), 82 publications
  • Nature Communications, 15 publications
  • Nature Biotechnology, 14 publications
  • Proceedings of the National Academy of Sciences, 9 publications
  • Nature, 7 publications

Recent notable papers authored by or involving George M. Church include:

  • "A Deep Learning Approach to Antibiotic Discovery," 2020, Cell
  • "Reprogramming to recover youthful epigenetic information and restore vision," 2020, Nature
  • "A robust benchmark for detection of germline large deletions and insertions," 2020, Nature Biotechnology
  • "Single-sequence protein structure prediction using a language model and deep learning," 2022, Nature Biotechnology
  • "Low-N protein engineering with data-efficient deep learning," 2021, Nature Methods

Frequent co-authors collaborating with George M. Church include:

  • Richie E. Kohman
  • Pranam Chatterjee
  • Christian Kramme
  • Elaine T. Lim
  • Yingleong Chan

George M. Church has received several awards recognizing contributions in the scientific community:

  • Member of the National Academy of Engineering (2012) for contributions to human genome sequencing technologies and DNA synthesis and assembly
  • Benjamin Franklin Medal, Franklin Institute (2011)
  • Member of the National Academy of Sciences (2011)
  • Promega Biotechnology Research Award, American Society for Microbiology (2009)
  • Fellow of the American Association for the Advancement of Science (AAAS) (year 1930)

Best Publications

  • RNA-Guided Human Genome Engineering via Cas9

    Prashant Mali;Luhan Yang;Kevin M. Esvelt;John Aach

  • Genomic sequencing

    G M Church;W Gilbert

  • The ENCODE (ENCyclopedia of DNA elements) Project

    E. A. Feingold;P. J. Good;M. S. Guyer;S. Kamholz

  • Systematic determination of genetic network architecture

    Saeed Tavazoie;Jason D. Hughes;Michael J. Campbell;Raymond J. Cho

  • Biclustering of Expression Data

    Yizong Cheng;George M. Church

  • CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering.

    Prashant Mali;John Aach;P Benjamin Stranges;Kevin M Esvelt

  • Accurate Multiplex Polony Sequencing of an Evolved Bacterial Genome

    Jay Shendure;Gregory J. Porreca;Nikos B. Reppas;Xiaoxia Lin

  • A Deep Learning Approach to Antibiotic Discovery

    Jonathan M. Stokes;Kevin Yang;Kyle Swanson;Wengong Jin

  • Genome engineering in Saccharomyces cerevisiae using CRISPR-Cas systems

    James E. DiCarlo;Julie E. Norville;Prashant Mali;Xavier Rios

  • Programming cells by multiplex genome engineering and accelerated evolution

    Harris H. Wang;Farren J. Isaacs;Peter A. Carr;Zachary Z. Sun

  • Highly efficient Cas9-mediated transcriptional programming

    Alejandro Chavez;Jonathan Scheiman;Suhani Vora;Benjamin W Pruitt

  • Multiplex and homologous recombination–mediated genome editing in Arabidopsis and Nicotiana benthamiana using guide RNA and Cas9

    Jian-Feng Li;Julie E Norville;John Aach;Matthew McCormack

  • Analysis of optimality in natural and perturbed metabolic networks

    Daniel Segrè;Dennis Vitkup;George M. Church

  • Assessing computational tools for the discovery of transcription factor binding sites.

    Martin Tompa;Nan Li;Timothy L. Bailey;George M. Church

  • Cas9 as a versatile tool for engineering biology

    Prashant Mali;Kevin M Esvelt;George M Church;George M Church

  • Human Genome Sequencing Using Unchained Base Reads on Self-Assembling DNA Nanoarrays

    Radoje Drmanac;Andrew B. Sparks;Matthew J. Callow;Aaron L. Halpern

  • Rapid prototyping of 3D DNA-origami shapes with caDNAno

    Shawn Michael Douglas;Adam H. Marblestone;Surat Teerapittayanon;Alejandro Vazquez

  • Next-Generation Digital Information Storage in DNA

    George M. Church;George M. Church;Yuan Gao;Sriram Kosuri;Sriram Kosuri

  • Computational identification of Cis -regulatory elements associated with groups of functionally related genes in Saccharomyces cerevisiae

    Jason D Hughes;Preston W Estep;Saeed Tavazoie;George M Church

  • Discrimination between Paralogs using Microarray Analysis: Application to the Yap1p and Yap2p Transcriptional Networks

    Barak A. Cohen;Yitzhak Pilpel;Robi D. Mitra;George M. Church

Frequent Co-Authors

Prashant Mali
Prashant Mali University of California, San Diego
Jay Shendure
Jay Shendure University of Washington
Harris H. Wang
Harris H. Wang Columbia University
Konrad P. Kording
Konrad P. Kording University of Pennsylvania
Kun Zhang
Kun Zhang University of California, San Diego
João Pedro de Magalhães
João Pedro de Magalhães University of Liverpool
Jin Billy Li
Jin Billy Li Stanford University

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