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Timothy K. Lu

Timothy K. Lu

D-Index & Metrics

Biology and Biochemistry

D-Index
78
Citations
24983
World Ranking
4499
National Ranking
2186

Overview

Timothy K. Lu is affiliated with the Massachusetts Institute of Technology (MIT) in the United States. Their research spans several interconnected areas within biochemistry, genetics, molecular biology, and medicine, focusing particularly on the application of synthetic biology and genetic engineering to develop novel therapeutic and diagnostic technologies.

The primary fields of study in Lu's work include Biochemistry, Genetics and Molecular Biology, with significant involvement in Medicine. Their subfields of expertise cover Molecular Biology, Oncology, Biomedical Engineering, Immunology, and Genetics.

Lu's research topics mainly center on CRISPR and genetic engineering techniques, CAR-T cell therapy research, antimicrobial peptides and activities, immune cell function and interaction, advanced biosensing and bioanalysis techniques, bacterial genetics and biotechnology, and biosensors and analytical detection.

Frequent co-authors collaborating with Lu include Yong Lai, Tzu-Chieh Tang, Russell M. Gordley, Jicong Cao, and Chen-Ting Lee. These partnerships reflect a multidisciplinary approach involving biochemical engineering, synthetic biology, and therapeutic development.

Lu's contributions have been published in various scientific venues, with frequent publications in bioRxiv (Cold Spring Harbor Laboratory), Regular and Young Investigator Award Abstracts, Nature Communications, Cancer Research, and Cell Systems. These journals and platforms indicate a balance between preprint dissemination and peer-reviewed research in high-impact journals related to biomedical science and cancer research.

Selected notable recent papers by Lu include:

  • Development and Challenges of Antimicrobial Peptides for Therapeutic Applications, 2020, Antibiotics
  • Materials design by synthetic biology, 2020, Nature Reviews Materials
  • Living materials with programmable functionalities grown from engineered microbial co-cultures, 2021, Nature Materials
  • Engineering living therapeutics with synthetic biology, 2021, Nature Reviews Drug Discovery
  • Hydrogel-based biocontainment of bacteria for continuous sensing and computation, 2021, Nature Chemical Biology

Best Publications

  • Dispersing biofilms with engineered enzymatic bacteriophage

    Timothy K. Lu;James J. Collins

  • Sequence-specific antimicrobials using efficiently delivered RNA-guided nucleases

    Robert J Citorik;Mark Mimee;Timothy K Lu

  • Synthetic gene networks that count.

    Ari E. Friedland;Timothy K. Lu;Timothy K. Lu;Xiao Wang;David Shi

  • Engineered bacteriophage targeting gene networks as adjuvants for antibiotic therapy.

    Timothy K. Lu;James J. Collins

  • Synthetic circuits integrating logic and memory in living cells

    Piro Siuti;John Yazbek;Timothy K Lu

  • Surface Charge-Switching Polymeric Nanoparticles for Bacterial Cell Wall-Targeted Delivery of Antibiotics

    Aleksandar F. Radovic-Moreno;Timothy K. Lu;Vlad A. Puscasu;Christopher J. Yoon

  • Synthetic analog computation in living cells

    Ramiz Daniel;Jacob R. Rubens;Rahul Sarpeshkar;Timothy K. Lu

  • Multiplexed and Programmable Regulation of Gene Networks with an Integrated RNA and CRISPR/Cas Toolkit in Human Cells

    Lior Nissim;Samuel D. Perli;Alexandra Fridkin;Pablo Perez-Pinera

  • An ingestible bacterial-electronic system to monitor gastrointestinal health.

    Mark Mimee;Phillip Nadeau;Alison Hayward;Sean Carim

  • Strong underwater adhesives made by self-assembling multi-protein nanofibres.

    Chao Zhong;Thomas Gurry;Allen A. Cheng;Jordan Downey

  • Genetically Engineered Phages: a Review of Advances over the Last Decade

    Diana P. Pires;Diana P. Pires;Sara Cleto;Sanna Sillankorva;Joana Azeredo

  • Development and Challenges of Antimicrobial Peptides for Therapeutic Applications

    Charles H. Chen;Timothy K. Lu

  • Next-generation synthetic gene networks

    Timothy K Lu;Ahmad S Khalil;James J Collins;James J Collins

  • Synthesis and patterning of tunable multiscale materials with engineered cells

    Allen Y. Chen;Zhengtao Deng;Amanda N. Billings;Urartu O. S. Seker

  • The next generation of bacteriophage therapy

    Timothy K Lu;Michael S Koeris

  • Tunable and Multifunctional Eukaryotic Transcription Factors Based on CRISPR/Cas

    Fahim Farzadfard;Samuel D. Perli;Timothy K. Lu

  • A Synthetic Biology Framework for Programming Eukaryotic Transcription Functions

    Ahmad S. Khalil;Timothy K. Lu;Caleb J. Bashor;Cherie L. Ramirez

  • 3D Printing of Living Responsive Materials and Devices.

    Xinyue Liu;Hyunwoo Yuk;Shaoting Lin;German Alberto Parada

  • Engineering Modular Viral Scaffolds for Targeted Bacterial Population Editing

    Hiroki Ando;Sebastien Lemire;Diana P. Pires;Timothy K. Lu

  • Peptide Design Principles for Antimicrobial Applications.

    Marcelo D.T. Torres;Shanmugapriya Sothiselvam;Timothy K. Lu;Cesar de la Fuente-Nunez

Frequent Co-Authors

Octavio L. Franco
Octavio L. Franco Universidade Católica de Brasília
Rahul Sarpeshkar
Rahul Sarpeshkar Dartmouth College
David J. Craik
David J. Craik University of Queensland
Chunhai Fan
Chunhai Fan Chinese Academy of Sciences
Zhengtao Deng
Zhengtao Deng Nanjing University

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